Clinical trials: Implementation, open to volunteers
Sleep, Postpartum Depression
The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers
Insufficient and disrupted sleep are rarely addressed in expectant and new mothers, despite evidence that disturbed sleep is a modifiable risk factor for negative health outcomes for mothers and their children.
- Conditions
- Sleep, Postpartum Depression, Pregnancy Related, Insomnia
- Trial name
- NCT06737055
- Testing
- Education about behavioral strategies to improve sleep
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Hematologic Cancer, Acute Myeloid Leukaemia (AML)
Home-based Intravenous Cytarabine Treatment for Acute Myeloid Leukemia: a National Danish Study of Feasibility, Costs, and Implementation
The goal of this observational multicenter feasibility and implementation study is to evaluate home-based treatment with intravenous Cytarabine for patients with acute myeloid leukemia in Denmark.
- Conditions
- Hematologic Cancer, Acute Myeloid Leukaemia (AML), Hospital At Home, Home-based Chemotherapy
- Trial name
- HOME-CALM (NCT07802015)
- Volunteers
- 80 people
- Sponsor
- Zealand University Hospital
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Consumption
Pilot of an Intervention to Reduce Alcohol Use and Improve ART Adherence Among Men Living With HIV With Pregnant Partners in Uganda.
Hazardous alcohol use, which is common among men in Uganda, is a primary driver of both HIV risk and intimate partner violence (IPV) in this setting.
- Trial name
- Kisoboka Amaka (NCT06900634)
- Testing
- Kisoboka Amaka, Screening and Referral
- Where
- Uganda
- Volunteers
- 60 people
- Sponsor
- San Diego State University
Rotator Cuff Related Shoulder Pain
Implementation of Shoulder School in Albania
Shoulder pain is a common musculoskeletal condition that can cause pain, movement limitations, disability, and difficulties performing daily and occupational activities.
- Trial name
- NCT07885878
- Testing
- Shoulder school, Standard Care (in control arm)
- Volunteers
- 50 people
- Sponsor
- University of Valladolid
Delivery of Health Care, HIV Infections
Differentiated Service Delivery (DSD) for People Living with HIV (PLHIV) and Comorbidities
This is an implementation study evaluating differentiated service delivery model for the care of comorbidities for people living with HIV (PLWH).
- Trial name
- NCT06738134
- Where
- Hong Kong
- Volunteers
- 300 people
- Sponsor
- Chinese University of Hong Kong
Binge Alcohol Consumption, Binge Drinking
Peer-Led Intervention To Reduce Alcohol Binge Drinking Among University Students In Romania
The goal of this clinical trial is to learn if a behavioural intervention to change binge drinking habits in university students in Romania is feasible.
- Trial name
- NCT07193030
- Testing
- Peer-led Alcohol Brief Intervention (identification + advice)
- Volunteers
- 120 people
- Sponsor
- International Agency for Research on Cancer
Neurologic Disorder
Tele-reha Versus Paper-based Aftercare Programme Following Inpatient Rehabilitation
The goal of this three-armed, observer-blinded, randomised controlled trial is to (i) to implement a telerehabilitation intervention in routine care after an inpatient rehabilitation stay for people insured with the Social…
- Trial name
- NCT05940584
- Testing
- Tele-Reha provided with EvoPads, Paper-based exercises with option to do tele-reha afterwards, Only paper-based exercises
- Where
- Austria
- Volunteers
- 285 people
- Sponsor
- Medical University of Vienna
Colorectal Cancer Screening, Diabetes Mellitus, Type 2
Aim 3, Optimizing CRC Screening in Patients With Diabetes in Safety-net Primary Care Settings
This mixed methods study evaluates the effectiveness and feasibility of a multi-level (patient, team, organizations) intervention to optimize CRC screening for patients with diabetes in primary care safety-net settings.
- Trial name
- NCT05785780
- Testing
- Targeted CRC Screening Toolkit
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Alcohol Use Disorder, Alcohol-related Liver Disease
Implementation of Mobile-based Programs for Alcohol Cessation in Treatment of Alcohol-associated Liver Disease
This protocol describes a randomized controlled trial testing the effectiveness and implementability of the CHESS Health Connections smartphone application among patients with alcohol-associated liver disease (ALD) at two medical…
- Trial name
- IMPACT-ALD (NCT06305624)
- Testing
- Connections App
- Where
- 3 sites in United States
- Volunteers
- 298 people
- Sponsor
- University of Wisconsin, Madison
Nausea With Vomiting Chemotherapy-Induced, Depression, Reactive
Implementation of Personalized Medicine for Optimal Drug Therapy in Cancer
A prospective longitudinal cohort study that will assess the effect of a Personalized Medicine (PM) clinic recommendations on pharmacogenetic variation and/or interacting drugs on plasma drug exposure, effectiveness or toxicity…
- Conditions
- Nausea With Vomiting Chemotherapy-Induced, Depression, Reactive, Cancer Pain
- Trial name
- NCT05830279
- Testing
- Pharmacogenetic testing, Drug-Drug interaction analysis
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Cervical Cancer Screening, Gynecologic Cancers
Compliance to Cervical Cancer Chemoradiation Guidelines: A Multicentric Implementation Audit and Resource Assessment Initiative of National Cancer Grid of India
This is a combination of retrospective and prospective observational study that will be performed across NCG and other participating centers to report compliance to chemoradiation for cervical cancer.
- Conditions
- Cervical Cancer Screening, Gynecologic Cancers, Treatment Compliance, Chemoradiotherapy
- Trial name
- NCG-Compliance (NCT07290972)
- Testing
- Not applicable- observational study
- Where
- 2 sites in India
- Volunteers
- 618 people
- Sponsor
- Tata Memorial Hospital
Spinal Cord Injuries, Aging
Exercise and Nutrition Education for Older Adults With Spinal Cord Injury: A Pilot Randomized Controlled Trial
Older adults living with a spinal cord injury (SCI) experience an increased burden of secondary health conditions than, coupled with age-related complications, may negatively affect physical and mental health, as well as…
- Trial name
- NCT07845851
- Testing
- Individualized Exercise Training, Nutrition Education, Behavioral Support
- Volunteers
- 24 people
- Sponsor
- Wayne State University
Implementation Science
Leveraging Telepsychology and Behavioral Economics to Increase Fidelity to CBT
The goal of this study is to develop and test a telehealth tool intended to support community mental health clinicians to deliver cognitive behavioral therapy (CBT). The main aims of the study are to: 1.
- Trial name
- BENEFITS (NCT06601062)
- Testing
- Tele-BE
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Digital Health Intervention, Remote Consultation, Teleconsultation
Evaluation and Implementation of Digital Health Ecosystem in Academic Health Center
Mobile health technologies, such as smartwatches, wearable sensors, and digital applications, have the potential to support healthier lifestyles and improve the management of health conditions.
- Conditions
- Digital Health Intervention, Remote Consultation, Teleconsultation, Lifestyle Factors, Stress
- Trial name
- e-IDEA (NCT07831837)
- Testing
- Integrated Digital Health Ecosystem, Usual Primary Care
- Where
- 2 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Laval University
Heart Failure, Care Givers
Heart Failure Carer Support Programme: Implementation Testing in the UK.
Background: Heart failure (HF) is widespread in the United Kingdom (UK). Many of these patients rely on support from family carers who are ill-prepared and supported for this role.
- Conditions
- Heart Failure, Care Givers, Self Management
- Trial name
- HELP (NCT07373041)
- Testing
- HEart faiLure carer support Programme (HELP)
- Where
- 5 sites in United Kingdom
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Colorectal Cancer, Premalignant Colon Lesions
A Mobile Application to Improve the Quality of Colonoscopy in Colorectal Cancer Screening Program (PrepColon APP)
Colonoscopy is the gold standard for the diagnosis and resection of preneoplastic lesions, allowing the prevention of colon cancer.
- Trial name
- PREPCOLON (NCT06314022)
- Testing
- Mobile application for colonoscopy preparation instructions
- Where
- 2 sites in Spain
- Volunteers
- 470 people
- Sponsor
- Hospital del Rio Hortega
Stroke, Acute, Ischemic Stroke, Acute
Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition
Most stroke patients are initially evaluated at the closest hospital but some need to be transferred to a hospital that can provide more advanced care.
- Conditions
- Stroke, Acute, Ischemic Stroke, Acute, Hemorrhagic Stroke
- Trial name
- HI-SPEED (NCT06094478)
- Testing
- HI-SPEED Protocol
- Where
- 8 sites in United States
- Volunteers
- 900 people
- Sponsor
- University of Chicago
Acquired Brain Injury, Mental Health
Occupational Therapy for Mental Health and Engagement in Neurorehabilitation
Changes in mental health are common after acquired brain injury (ABI), defined as any traumatic or non-traumatic injury to the brain after birth, affecting approximately 1 in 3 adults with ABI.
- Conditions
- Acquired Brain Injury, Mental Health, Depressive Symptoms, Anxiety Symptoms
- Trial name
- OT for ME (NCT07375485)
- Testing
- Multifaceted implementation program
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Pediatric ALL, Sepsis
Evaluation of Pediatric eCART Implementation
This is a study comparing 3 years of retrospective data (pre-implementation) to 2 years of prospective data after the implementation of a pediatric version of Electronic Cardiac Arrest Risk Triage (pediatric eCART), a clinical…
- Trial name
- NCT06771830
- Testing
- Pediatric eCART
- Where
- United States
- Volunteers
- 30,000 people
- Sponsor
- University of Wisconsin, Madison
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A
This Study will comprehensively evaluate a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartA (NCT06223867)
- Testing
- Jaspr App + JAH, ETAU
- Where
- United States
- Volunteers
- 670 people
- Sponsor
- University of Massachusetts, Worcester
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