Clinical trials: Implementation Research, active
Stroke, Stroke Rehabilitation
Volunteer Facilitated Discharge Assistance and Supports at Home (DASH) for People With Stroke
The goal of this clinical trial is to learn if a home visit by a trained volunteer can improve stroke recovery after a stroke survivor is discharged home from the hospital. The main questions it aims to answer are: 1.
- Conditions
- Stroke, Stroke Rehabilitation, Transitional Care
- Trial name
- DASH (NCT07590076)
- Testing
- Discharge Assistance and Supports at Home (DASH)
- Where
- 6 sites in Canada
- Volunteers
- 840 people
- Sponsor
- Bruyère Health Research Institute.
MASH, MASLD
Global Research Initiative for Patients Screening on MASH
GRIPonMASH will assist (primary) health care providers clinicians to implement the latest patient care pathway, as described by the European Association for the Study of the Liver (EASL), to identify patients at risk of severe…
- Conditions
- MASH, MASLD, MASH With Fibrosis, Fibrosis, Liver
- Trial name
- GRIPonMASH (NCT05651724)
- Where
- 13 sites in Belgium, Czechia and 8 more
- Volunteers
- 10,000 people
- Sponsor
- Julius Clinical
Pediatric Cancer
Multisite Implementation of COMPRENDO
COMPRENDO (ChildhOod Malignancy Peer Research NavigatiOn) is a multi-site randomized clinical trial (RCT) that uses a Hybrid Type 1 design, to test the effects of a clinical intervention on patient-level outcomes, while exploring…
- Trial name
- COMPRENDO (NCT06055296)
- Testing
- COMPRENDO Peer Navigation Intervention
- Where
- 4 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Psychiatric Problem, Child Neglect
Implementing Dyadic Developmental Psychotherapy (DDP) - Evaluation Research
The objective of this study is to evaluate the implementation and use of Dyadic Developmental Psychotherapy (DDP) in three centra, with particular focus on its potential effects on the quality of the observable caregiver-child…
- Conditions
- Psychiatric Problem, Child Neglect, Maltreatment, Child Behavior Problem
- Trial name
- NCT04763720
- Testing
- Dyadic Developmental Psychotherapy
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Sykehuset Telemark
Surgery, Geriatric Assessment
Implementation Pilot of Preoperative CGA Before Major Surgery
The goal of this clinical trial is to test whether a new implementation package can help older adults prepare for major surgery.
- Conditions
- Surgery, Geriatric Assessment, Health Services Research, Implementation Science
- Trial name
- NCT06184724
- Testing
- Implementation Package for CGA, Routine Clinical Care
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Breast Cancer
Clinical Breast Examination and Patient Navigation Intervention in Sub-Saharan Africa
Brief summery Prolonged presentation, along with diagnostic and treatment delays, remain significant problems for breast cancer care in sub-Saharan Africa , primarily due to low health-seeking behaviour, lack of access, long…
- Trial name
- NCT07023198
- Testing
- Clinical breast examination and Navigation
- Where
- Ethiopia
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Addis Ababa University
Infusions, Intravenous, Implementation Science
Validation of the Effectiveness of the CFIR - ERIC Matching Tool in Implementation Research
The goal of this implementation study is to learn if the CFIR-ERIC matching tool is effective indeveloping implementation strategies for pediatric nurse.
- Trial name
- NCT07184489
- Testing
- implementation strategies
- Where
- China
- Volunteers
- 394 people
- Sponsor
- Children's Hospital of Fudan University
HIV Antiretroviral Therapy (ART) Adherence, Alcohol Consumption
Pilot of an Intervention to Reduce Alcohol Use and Improve ART Adherence Among Men Living With HIV With Pregnant Partners in Uganda.
Hazardous alcohol use, which is common among men in Uganda, is a primary driver of both HIV risk and intimate partner violence (IPV) in this setting.
- Trial name
- Kisoboka Amaka (NCT06900634)
- Testing
- Kisoboka Amaka, Screening and Referral
- Where
- Uganda
- Volunteers
- 60 people
- Sponsor
- San Diego State University
Coverage of Vitamin A Supplementation, Coverage of Immunization
OPTIMIZING ROUTINE DELIVERY OF ESSENTIAL CHILD HEALTH AND NUTRITION PACKAGE THROUGH PRIMARY HEALTH CARE CONTACTS
The primary objective of the study is to assess whether optimization of an essential package of health and nutrition services for children under five years of age using vitamin A supplementation touch points (i.e., the…
- Conditions
- Coverage of Vitamin A Supplementation, Coverage of Immunization, Feasibility and Fidelity of Implementation
- Trial name
- NCT06949930
- Testing
- Optimized package of child essential health and nutrition services, Standard package of essential child and nutrition services
- Where
- 2 sites in Kenya, Senegal
- Volunteers
- 1,928 people, healthy volunteers welcome
- Sponsor
- Nutrition International
Opioid Use Disorder, HIV Infections
Buprenorphine Integration Research and Community Health
The goal of this clinical trial is to evaluate an intervention strategy in introducing screen/evaluate/treat (SET) procedures for HIV/ hepatitis C/ and Opioid Use Disorder in Primary Care Clinics in West Virginia.
- Conditions
- Opioid Use Disorder, HIV Infections, Hepatitis C
- Trial name
- BIRCH (NCT05668780)
- Testing
- NIATx Coaching
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Acute Heart Failure (AHF), Implementation Research
Implementation of Acute Heart Failure Checklist
Patients with acute heart failure (AHF) commonly present to the emergency department (ED) with difficulty breathing and often have poor outcomes or death.
- Trial name
- NCT07727304
- Testing
- CAEP Acute Heart Failure (AHF) Best Practices Checklist Implementation, Usual care
- Where
- Canada
- Volunteers
- 5,040 people
- Sponsor
- Ottawa Hospital Research Institute
HIV Infections
A Systems Analysis and Improvement Approach for Optimizing HIV Service Delivery in Syringe Services Programs
The goal of this clinical trial is to assess the effectiveness of an evidence-based, organizational-level implementation strategy, the Systems Analysis and Improvement Approach, in improving HIV service delivery (SAIA-SSP-HIV) in…
- Trial name
- SAIA-SSP-HIV (NCT06025435)
- Testing
- SAIA-HIV-SSP
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Prostate Cancer, Risk Assessment
PROstate Cancer Risk Calculator for ACTionable Clinical Decision-making in Nigeria
This study is a pilot trial that builds on findings from the validation of prostate cancer risk calculators in Nigerian men. The goal of the overall study is to improve the early detection of prostate cancer in a high-risk…
- Conditions
- Prostate Cancer, Risk Assessment, Clinical Decision Support Systems, Predictive Value of Tests
- Trial name
- PROACT (NCT07733440)
- Testing
- (a) Training and (b) Supported risk assessment
- Where
- Nigeria
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University
Cancer, Latin America and the Caribbean Code Against Cancer (LAC Code)
Feasibility Study to Actively Disseminate the Latin America and the Caribbean Code Against Cancer in Primary Healthcare Centers
Phase II non-randomized four-arm study (before/after pragmatic trial) that will test 2 different implementation strategies either combined or separately for the dissemination of the Latin America and the Caribbean Code Against…
- Trial name
- FLACC-Brazil (NCT06965608)
- Testing
- WhatsApp-Based Cancer Prevention Messaging, Online Cancer Prevention Workshop for Healthcare Professionals, Combined WhatsApp Messaging and Online Workshop
- Where
- Brazil
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Physical Activity, Health Promotion
YoPA - A Youth-centred Participatory Action
Background A vast majority of adolescents do not meet guidelines for healthy physical activity, sedentary behaviour, and sleep, posing major risks for developing multiple non-communicable diseases.
- Conditions
- Physical Activity, Health Promotion, Sleep, Screen Use
- Trial name
- YoPA (NCT06181162)
- Testing
- Social and/or physical environmental interventions
- Where
- 4 sites in Denmark, Netherlands and 2 more
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Melanoma
MElanoma Research Lymph Node Prediction Implementation National_001
MERLIN_001 is a prospective registry study of a primary melanoma gene-signature to predict sentinel node (SN) status and to determine its prognostic value for more accurate staging of SN-negative melanoma patients.
- Trial name
- MERLIN_001 (NCT04759781)
- Where
- 9 sites in United States
- Volunteers
- 1,820 people
- Sponsor
- SkylineDx
Mixed Method Implementation Study, Nursing
The Effect of SBAR Communication Program on Nursing Students' Perceptions of Clinical Decision Making and Medical Error Prevention Levels: A Mixed Methods Study
In clinical settings, teamwork plays a vital role in improving patient care outcomes. Effective and structured communication within the team ensures that a holistic service is provided to patients.
- Conditions
- Mixed Method Implementation Study, Nursing, Nursing Students, Nursing Education Research
- Trial name
- NCT06978634
- Testing
- SBAR training with cases
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aytap DİNCER
TBI (Traumatic Brain Injury), Implementation Research
Emergency Department Implementation of the i-STAT Alinity Traumatic Brain Injury Whole Blood Test
The objective of this study is to identify determinants for implementing the i-STAT Alinity whole blood traumatic brain injury (TBI) test for its Food and Drug Administration (FDA)-indicated use and to evaluate other potential…
- Trial name
- EDI (NCT07373509)
- Testing
- i-STAT Alinity TBI test
- Where
- United States
- Volunteers
- 340 people
- Sponsor
- Shawn Eagle
Implementation Research
Implementation of Naturalistic Developmental Behavioral Intervention (NDBI) Through Coaching Caregivers of Young Autistic Children
Naturalistic developmental behavioral interventions (NDBIs) are a newer class of evidence-based interventions for young autistic children to promote their positive developmental or behavioral outcomes.
- Trial name
- NCT06923553
- Testing
- NDBIs
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Texas at Austin
Urinary Retention, Hip Fractures
Onset PrevenTIon of Urinary Retention in Orthopaedic Nursing and Rehabilitation
Urinary retention (UR) is a common problem in older people undergoing hip surgery. Untreated UR can lead to bladder distention and a permanent damage of the bladder, which can cause both physical and psychical suffering as well…
- Conditions
- Urinary Retention, Hip Fractures, Hip Arthritis
- Trial name
- OPTION (NCT04700969)
- Testing
- : A support program to facilitate implementation of evidence-based practice for postoperative urinary retention
- Where
- 17 sites in Sweden
- Volunteers
- 20 people
- Sponsor
- Örebro University, Sweden