Clinical trials: Implementation Science
Hernia, Inguinal, Hernia, Femoral
Recover@Home Postoperative Follow-up Study
This proposal describes a human subjects research study evaluating mHealth Ambulatory Surgery with Follow-up Nurse (Recovery@Home), as an alternative postoperative care pathway for selected low-acuity surgical procedures in…
- Conditions
- Hernia, Inguinal, Hernia, Femoral, Hernia, Umbilical, Hernia, Ventral
- Trial name
- NCT07714343
- Testing
- Recovery@home
- Where
- 4 sites in Uganda
- Volunteers
- 194 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cancer
Cancer Prevention and Early Detection Among the Homeless Population: The Health Navigator Model
Prevention and early detection are key for the decrease of cancer-related mortality. However, socially deprived population groups don't have the privilege of unburdened access to the healthcare system.
- Trial name
- CANCERLESS (NCT05406687)
- Testing
- Health Navigator Model
- Where
- 18 sites in Austria, Greece and 2 more
- Volunteers
- 654 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Substance Abuse
Efficacy of Centervention-ATOD: An Implementation Tool for Dissemination of Evidence-based Programs for Substance Abuse
The pilot test of Centervention-ATOD, a customizable suite of online tools specifically designed to support quality implementation and sustainability of any ATOD-EBP within real-world service settings, will evaluate whether the…
- Trial name
- CV-ATOD (NCT03084406)
- Testing
- Centervention-ATOD (CV-ATOD)
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- 3-C Institute for Social Development
Dementia, Cognitive Dysfunction
Preventing Loss of Independence Through Exercise in Community Living Centers
Approximately 40,000 older Veterans with complex care needs receive long-term care in VA Community Living Centers (CLCs). Many CLC staff have limited specialized training to engage Veterans with dementia.
- Trial name
- PLIE-CLC (NCT06972004)
- Testing
- Preventing Loss of Independence through Exercise (PLIE)
- Where
- United States
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Human Papilloma Virus Infection, Carcinoma in Situ of Uterine Cervix
Community-Driven Cervical Cancer Prevention in Western Kenya
There are many challenges to implementation of cervical cancer prevention in resource-limited countries, despite evidence based screening and treatment strategies.
- Trial name
- NCT02124252
- Testing
- Community-based testing with standard linkage to care, Community-based HPV testing with enhanced linkage to care
- Where
- Kenya
- Volunteers
- 7,200 people, healthy volunteers welcome
- Sponsor
- Duke University
Colo-rectal Cancer
Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot Study
The investigators will use a mixed methods study i.e. focus groups involving CHC staff as well as quantitative study which involves analyzing data that is available from the EHR and DRVS population management platform.
- Trial name
- NCT05524428
- Testing
- Implementation Science Strategy
- Where
- 4 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Stress, Postpartum Depressive Disorder
Powerly - Science-based Digital Intervention Preventing Postpartum Depression and Anxiety
The goal of this clinical trial is to determine if the Powerly app can help prevent postpartum depression and anxiety in healthy pregnant women.
- Conditions
- Stress, Postpartum Depressive Disorder, Postpartum Anxiety
- Trial name
- POWERLY app (NCT06610552)
- Testing
- Powerly
- Where
- Switzerland
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Marta Marciniak
Maternal Mortality Disparities, Maternal Morbidity Disparities
Scaling up Maternal Health Equity Best Practices
This study works with prenatal and postnatal care providers in 12 Michigan counties to scale up best practices for maternal health equity.
- Trial name
- NCT06541951
- Testing
- Services as usual, Scale-up implementation approach
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Michigan State University
HIV
CHWs, mHealth, and Combination HIV Prevention
Kasensero, a fishing community on Lake Victoria in Uganda, is a representative HIV "hotspot" with extremely high HIV prevalence (44.3%) and incidence (~3.9/100py), yet low HIV service utilization.
- Trial name
- mLAKE (NCT02556957)
- Testing
- HealthScouts, Standard of Care
- Where
- Uganda
- Volunteers
- 3,773 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Psychotic Disorders
Implementation of Family Involvement for Persons With Psychotic Disorders.
This study will develop and evaluate a complex intervention to implement guidelines on family involvement for patients with psychotic disorders (F20-29 in International Classification of Diseases ICD-10) in community mental…
- Trial name
- IFIP (NCT03869177)
- Testing
- Implementation support program
- Where
- 15 sites in Norway
- Volunteers
- 460 people
- Sponsor
- University of Oslo
HPV Vaccine
Effectiveness of Vaccine Chatbot on HPV Vaccine Awareness and Vaccination in China
This interventional study targets female students in junior middle school. It goal is to evaluate the effectiveness of a vaccine chatbot on HPV vaccine awareness and vaccination. The main questions it aims to answer are: 1.
- Trial name
- NCT06227689
- Testing
- Vaccine chatbot that offering HPV vaccine-related information
- Where
- 2 sites in China
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Fudan University
Tuberculosis, Pulmonary, Rifampicin Resistant Tuberculosis
GeneXpert Performance Evaluation for Linkage to Tuberculosis Care
The investigators' overall objective is to assess the effectiveness, implementation and costs of a streamlined TB diagnostic evaluation strategy based around rapid, onsite molecular testing.
- Trial name
- XPEL-TB (NCT03044158)
- Testing
- GeneXpert I, Process re-design, Performance Feedback
- Where
- 20 sites in Uganda
- Volunteers
- 10,644 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cancer
Implementation of a Health System Intervention to Improve Quality of Cancer Care for Rural Patients
The purpose of this study is to implement and evaluate the recently developed Iowa Cancer Affiliate Network (ICAN) intervention.
- Trial name
- NCT05645328
- Testing
- Iowa Cancer Affiliate Network (ICAN)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Mary Charlton
Sickle Cell Disease
Integration of mHEALTH Into the Care of Patients With Sickle Cell Disease to Increase Hydroxyurea Utilization
This project proposes to develop, test and evaluate targeted interventions to improve clinical provider prescribing of and patient adherence to hydroxyurea (HU).
- Trial name
- NCT04080167
- Testing
- InCharge Health mobile application, HU Toolbox mobile application
- Where
- 7 sites in United States
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Cardiovascular Health Status, Smoking Status
Effectiveness and Implementation Evaluation of NeoMayor for Improving Cardiovascular Health in Chilean Older Adults
This study aims to evaluate the effectiveness and implementation of NeoMayor, a mobile health (mHealth) intervention designed to improve cardiovascular health among older adults at elevated cardiovascular risk in Chile.
- Conditions
- Cardiovascular Health Status, Smoking Status, Physical Activity, Diet Quality
- Trial name
- NEOMAYOR (NCT07633392)
- Testing
- NeoMayor App, Wearable Device Support, Human Health Coach Support
- Where
- 2 sites in Chile
- Volunteers
- 240 people
- Sponsor
- University of Chile
Implementation Science, Informed Consent
Implementing a Novel Consent Process for Biospecimen Research After Newborn Screening
The purpose of this study is to implement an electronic consent education process for the retention and research use of residual dried bloodspots at four hospitals in Michigan and assess the impact of the new education, both on…
- Conditions
- Implementation Science, Informed Consent, Neonatal Screening
- Trial name
- MICI (NCT06192511)
- Testing
- Educational Website and Video
- Where
- 2 sites in United States
- Volunteers
- 5,980 people, healthy volunteers welcome
- Sponsor
- Erin Rothwell
Psychological Trauma, Mental Health
Collaborative Organizational Approach to Selecting and Tailoring Implementation Strategies
The purpose of this study is to partner with the North Carolina Child Treatment Program (NC CTP) and the SAMHSA-funded National Child Traumatic Stress Network (NCTSN) to develop and pilot the Collaborative Organizational Approach…
- Trial name
- COAST-IS (NCT03799432)
- Testing
- COAST-IS, TF-CBT Learning Collaborative
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Migraine Headache
TelemEdiciNe-bAsed Cognitive TherapY for Migraines
The goal of this pilot study is to evaluate a bundle of implementation strategies at three Veteran Affairs Medical Centers (VAMCs) to facilitate the referral and adoption of a telehealth based, cognitive behavioral therapy…
- Trial name
- TENACITY (NCT04613362)
- Testing
- TENACITY Telehealth Cognitive Behavioral Therapy for Migraine, Behavioral Usual Care
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- VA Office of Research and Development
HIV/AIDS
Biomedical HIV/AIDS Prevention Program Yunnan
B-HAPPY is an implementation project to study the process by which pre-exposure prophylaxis (PrEP) is introduced and integrated into a specific international health system facing high rates of HIV incidence among men who have sex…
- Trial name
- B-HAPPY (NCT03992274)
- Testing
- Enhanced implementation of PrEP
- Where
- China
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Columbia University
Quality of Life
A Hybrid Effectiveness-Implementation and Cost-Utility Evaluation of a Support Programme for Informal Carers of People With Dementia in Primary Care (EsCuidar2)
The aim of this study is to evaluate whether the School of Caring programme improves quality of life and reduces caregiver burden among informal carers of people living with dementia.
- Trial name
- EsCuidar2 (NCT07861789)
- Testing
- School of Caring Programme
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina