Clinical trials: Implementation Science, active
Bronchiolitis, Clinical Phenotype
Short-Term Enteral Nutrition for Infants With Bronchiolitis in Pediatric Emergency Departments
Bronchiolitis is a common viral infection of the small airways that affects infants, particularly during respiratory syncytial virus epidemics.
- Conditions
- Bronchiolitis, Clinical Phenotype, Nutritionnal Impairment, Short-Term Enteral Nutrition
- Trial name
- STENP-PER (NCT07901400)
- Testing
- Usual inpatient bronchiolitis care, STENP-PER care pathway
- Where
- 8 sites in France
- Volunteers
- 448 people
- Sponsor
- Hospices Civils de Lyon
Breast Cancer, Ovarian Cancer
Navigation Intervention for Adolescent and Young Adult Cancer Survivors
The investigators propose to: 1) Adapt an evidence-based cancer-focused patient navigation (PN) program for the Adolescent and Young Adult (AYA) cancer survivor population; and 2) Plan and conduct an effectiveness-implementation…
- Conditions
- Breast Cancer, Ovarian Cancer, Cervical Cancer, Testicular Cancer
- Trial name
- NCT07406087
- Testing
- Adapted patient navigation program targeting adolescent and young adult cancer survivors
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Kaiser Permanente
Insomnia Disorder, Mild Traumatic Brain Injury
Sleep MAPP in the Polytrauma/TBI System of Care
This pilot implementation trial will evaluate the Sleep Disorder Management Assistance for Providers and Patients (Sleep MAPP) Care Pathway in one Veterans Health Administration Polytrauma/TBI System of Care clinic.
- Trial name
- Sleep MAPP (NCT07886398)
- Testing
- Sleep MAPP Care Pathway
- Where
- 2 sites in United States
- Volunteers
- 900 people
- Sponsor
- VA Office of Research and Development
Breast Cancer
Developing a Comprehensive Exercise Service for Breast Cancer Process
"Moving Together" (Juntas en Movimiento) is a hospital-based, comprehensive, and personalized exercise service designed for women diagnosed with breast cancer.
- Trial name
- NCT07380971
- Testing
- Supervised in-person exercise training, Supervised Online Exercise Training, Home-Based Autonomous Exercise Program
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- GO fit Lab- Ingesport
Inappropriate Prescribing, Implementation Science
Reduction of Low-value Prescribing Through Audit and Feedback
The objective is to estimate the effect attributable to a primary care pharmacist-led audit and feedback (AF) strategy compared to the currently used AF strategy as a management tool to evaluate healthcare performance focusing on…
- Conditions
- Inappropriate Prescribing, Implementation Science, Behavioral Sciences
- Trial name
- AFFAP (NCT07336550)
- Testing
- Usual AF, Facilitated AF
- Where
- Spain
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Knee Osteoarthritis
Implementing a Group Physical Therapy Program for Veterans (GroupPT): Function QUERI 3.0
Implementing Group Physical Therapy for Veterans with Knee Osteoarthritis (Group PT): Function QUERI 3.0 aims to compare two implementation approaches for implementing Group PT in 20 VA facilities using a type III…
- Trial name
- GroupPT (NCT07215572)
- Testing
- Implementation Strategy: Foundational Arm, Implementation Strategy: REACH Arm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Suicide, Primary Care
Implementing Suicide Prevention Into Primary Care in Nepal
Suicide remains a major contributor to global mortality, with particularly high and persistent rates in low-resourced settings such as South Asia.
- Trial name
- NCT07362056
- Testing
- Suicide Prevention Package (PSuPP)
- Where
- Nepal
- Volunteers
- 147 people
- Sponsor
- Yale University
Alzheimer Disease, Dementia
CONSTELLATIONS Living Lab: Improving the Care Transitions of Older Adults Living with Neurocognitive Disorders
The prevalence of major neurocognitive disorders (MNCDs), particularly Alzheimer's disease, among older adults is increasing. These individuals and their caregivers often face challenges due to inefficient and poorly coordinated…
- Conditions
- Alzheimer Disease, Dementia, Neurocognitive Decline
- Trial name
- NCT06608589
- Testing
- CoMPAS+ MNCDs Program - Quality improvement program targeting the care transitions of patients living with a major neurocognitive disorder and their caregivers
- Where
- Canada
- Volunteers
- 700 people
- Sponsor
- Laval University
HIV, Substance Use Disorder (SUD)
Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs
The goal of this study is to determine the feasibility and impact of delivering long-acting injectable cabotegravir HIV pre-exposure prophylaxis and suite of support services to adults who inject non-prescription drugs who are…
- Conditions
- HIV, Substance Use Disorder (SUD), Injection Drug Use
- Trial name
- ASCEND (NCT07199335)
- Testing
- APRETUDE (cabotegravir)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Ventilator-Associated Pneumonia (VAP), Neonatal, Bronchopulmonary Dysplasia (BPD)
National Surveillance and Prevention of Neonatal VAP
The goal of this observational study is to improve how hospital-acquired lung infections (called ventilator-associated pneumonia, or VAP) are diagnosed, treated and prevented in very low birth weight (VLBW) infants, babies born…
- Conditions
- Ventilator-Associated Pneumonia (VAP), Neonatal, Bronchopulmonary Dysplasia (BPD), Antibiotic-Resistant Organisms (AROs), Health-Care Associated Infection (HAI)
- Trial name
- NCT07109791
- Where
- Canada
- Volunteers
- 1,500 people
- Sponsor
- University of Alberta
Physical Inactivity, Dyslipidemia
Implementation Facilitation of Exercise is Medicine Greenville
A public health priority exists for the U.S. healthcare sector to integrate physical activity (PA) as a part of the patient care model.
- Conditions
- Physical Inactivity, Dyslipidemia, Obesity and Overweight, Hypertension
- Trial name
- NCT07340580
- Testing
- Clinic Implementation Facilitation
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Suicide
Implementing A Secure Firearm Storage Program in Illinois Health Centers in Partnership With AllianceChicago and the Illinois Primary Health Care Association (COMMUNITY ASPIRE)
This randomized controlled trial will take place in up to 15 community health centers across the state of Illinois. Researchers will be studying S.A.F.E.
- Trial name
- NCT06886776
- Testing
- Implementation package (training and facilitation)
- Where
- United States
- Volunteers
- 1,086 people
- Sponsor
- Northwestern University
Substance Use Disorder, Mental Health Disorder
Employing Peer Outreach and Whole Health in Recovery for Homeless-Experienced Veterans
Homelessness is a national crisis in the United States, particularly in the veteran population. Due to multiple chronic conditions, homeless individuals frequently become hospitalized or are treated in emergency departments.
- Conditions
- Substance Use Disorder, Mental Health Disorder, Homelessness
- Trial name
- EMPOWER (NCT07309224)
- Testing
- Employing Peer Outreach and Whole Health in Recovery (EMPOWER)
- Where
- United States
- Volunteers
- 278 people
- Sponsor
- VA Office of Research and Development
Alcohol-Related Disorders, Substance-Related Disorders
Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years
The goal of this clinical trial is to test the effectiveness of evidence-based Screening, Brief Intervention, and Referral to Treatment (SBIRT) among adult patients who screen positive to one or more risky alcohol or substance…
- Conditions
- Alcohol-Related Disorders, Substance-Related Disorders, Mental Health, Reproductive Health
- Trial name
- NCT05910580
- Testing
- Screening, Brief Intervention, and Referral to Treatment (SBIRT)
- Where
- 4 sites in United States
- Volunteers
- 400 people
- Sponsor
- Emory University
Type 1 Diabetes Mellitus (T1DM), Diabetes Distress
GlycoQuest: An AI-Adaptive CGM-Integrated Serious Game for Pediatric Type 1 Diabetes
Type 1 diabetes diagnosed in childhood requires rapid acquisition of complex self-management skills while children and caregivers are also adapting emotionally and socially to a chronic condition.
- Conditions
- Type 1 Diabetes Mellitus (T1DM), Diabetes Distress, Hypoglycemia (Diabetic), Family Conflict
- Trial name
- GlycoQuest (NCT07726680)
- Testing
- GlycoQuest Digital Therapeutic, Enhanced Digital Psychoeducation
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Shifa International Hospital
Hypertension
Implementation of a Beauty Salon-Based Strategy for Blood Pressure Management Among Women
CROWN is a two-arm, cluster-randomized pilot trial testing the feasibility and preliminary efficacy of a salon-based cardiovascular intervention - training stylists as Heart Health Stylists to conduct in-salon blood pressure…
- Trial name
- CROWN (NCT07042386)
- Testing
- CROWN Intervention, Enhanced Usual Care
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Alcohol Misuse
Bridging Opportunities for Substance Use Screening and Treatment for Teens With Chronic Illness
Adolescents with a chronic medical condition (A-CMC) are more likely to misuse and initiate alcohol and other drugs (AOD) at younger ages compared to adolescents without CMCs.
- Trial name
- BOSSTT (NCT07446075)
- Testing
- Screening, Brief Intervention, and Referral to Treatment (SBIRT)
- Volunteers
- 50 people
- Sponsor
- Faith Summersett Williams
ICU Patients, Surgical
Implementation of Clinical Nutrition Practice Guidelines in Surgical ICUs
The goal of this interventional clinical trial is to evaluate whether the implementation of an evidence-based, context-adapted clinical nutrition practice guideline can improve clinical nutrition management in surgical intensive…
- Conditions
- ICU Patients, Surgical, Nutrition Intervention, Enteral Nutrition
- Trial name
- NCT07337798
- Testing
- Guideline Implementation
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
ASCVD, LDL-C
Test 2 Treat: Can we Improve the Testing and Treatment of High Cholesterol in Patients Who Have Been Hospitalized for a Cardiac Event by Providing Education to Doctors and Patients?
The goal of this implementation trial is to learn if providing education to doctors and patients who have had a heart event works to prevent future heart problems. The main questions it aims to answer are: 1.
- Trial name
- T2T (NCT06471036)
- Testing
- Care Champion Intervention
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Duke University
Maternal Mortality Disparities, Maternal Morbidity Disparities
Scaling up Maternal Health Equity Best Practices
This study works with prenatal and postnatal care providers in 12 Michigan counties to scale up best practices for maternal health equity.
- Trial name
- NCT06541951
- Testing
- Services as usual, Scale-up implementation approach
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Michigan State University