Clinical trials: Improve Physical Activity
Asthma in Children, Obesity, Childhood
Reducing Exercise-induced Bronchoconstriction in Children With Asthma and Obesity
Guidelines from the American Thoracic Society strongly recommend interval warm-up exercise before planned exercise to reduce exercise-induced bronchoconstriction severity.
- Conditions
- Asthma in Children, Obesity, Childhood, Exercise Induced Bronchospasm
- Trial name
- NCT03586544
- Testing
- Albuterol Sulfate, Interval Warm-up exercise
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Impulse Control Disorders
Restoring Cognitive Control (ReCon) in Acute Nicotine Withdrawal
The purpose of this study is to explore the safety, tolerability and activity of SXC-2023 or placebo when dosed for 5 days in adults with tobacco use disorder who voluntarily abstain from the use of cigarettes.
- Trial name
- NCT03887429
- Testing
- SXC-2023
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Promentis Pharmaceuticals, Inc.
Healthy Participants
Strategic Daytime Napping Enhances Agility and Lowers Perceived Exertion
This study investigates how short daytime naps affect physical performance and perceived exertion in competitive male soccer players.
- Trial name
- NCT07264777
- Testing
- Strategic Napping Protocol, No Nap Condition (N0)
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Princess Nourah Bint Abdulrahman University
Colorectal Cancer, Chemotherapeutic Toxicity
Aerobic Fitness or Muscle Mass Training to Improve Colorectal Cancer Outcome
Evidence from randomized controlled trials shows that exercise during cancer treatment benefits physical fitness, fatigue and quality of life.
- Conditions
- Colorectal Cancer, Chemotherapeutic Toxicity, Survivorship, Lifestyle
- Trial name
- AMICO (NCT04754672)
- Testing
- Continuous aerobic and resistance exercise intervention, Continuous aerobic and aerobic interval exercise intervention
- Where
- 13 sites in Netherlands
- Volunteers
- 228 people
- Sponsor
- Radboud University Medical Center
Type 2 Diabetes Mellitus, Coronary Artery Disease
Exercise Training Improves Coronary Endothelial Dysfunction in Diabetes Mellitus Type 2 and Coronary Artery Disease
Patients with type 2 diabetes mellitus suffer from accelerated coronary artery disease. We will assess the effects of exercise training on coronary endothelial function, vascular structure, and inflammation both in serum and…
- Trial name
- NCT00693537
- Testing
- Exercise training
- Where
- Austria
- Sponsor
- Paracelsus Medical University
Metabolic Syndrome, Exercise
Time Restricted Eating (TRE) and High-Intensity Interval Training (HIIT) to Improve Health in Patients With Metabolic Syndrome (METS)
Studies in mice provide compelling evidence that feeding/fasting cycles can be altered to produce beneficial effects on weight loss and cardiometabolic health markers in the absence of caloric restriction.
- Conditions
- Metabolic Syndrome, Exercise, Weight Loss, Obesity
- Trial name
- TRE-HIIT-METS (NCT06501001)
- Testing
- High-Intensity Interval Training, Experimental: Time-Restricted Eating
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- University of Castilla-La Mancha
Peripheral Artery Disease
Telmisartan Plus Exercise to Improve Functioning in Peripheral Artery Disease
The TELEX trial will establish whether telmisartan alone improves walking performance in people with peripheral artery disease (PAD).
- Trial name
- TELEX (NCT02593110)
- Testing
- Supervised Treadmill Exercise Therapy, Telmisartan, "No exercise" control group
- Where
- 3 sites in United States
- Volunteers
- 114 people
- Sponsor
- Northwestern University
Osteoporosis, Osteoporotic Fracture of Vertebra
Development and Evaluation of an Exercise Intervention for Prevention of Vertebral Osteoporosis and Deformity in Postmenopausal Women
Osteoporotic fractures of the vertebrae (bones in the back) cause substantial pain and disability. Exercise could help to prevent these fractures by increasing bone strength and improving posture.
- Conditions
- Osteoporosis, Osteoporotic Fracture of Vertebra, Postural, Thoracic Kyphosis
- Trial name
- NCT04660825
- Testing
- A resistance band exercise programme, Control
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Amputation
Early Active Finger Exercises in Replanted Fingers
A controlled randomized trial, including patients undergoing finger replantation surgery. The Control Group will receive a standardized post operative rehabilitation regime, whilst the Intervention Group will receive a…
- Trial name
- NCT03383640
- Testing
- Active exercises
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Prehabilitation
Multimodal Prehabilitation Program That Combines Physical Exercise, Psychological Intervention and Nutritional Support to Improve the Response to Neoadjuvant Chemoterhapy in Early Breast Cancer Patients
The aim of this clinical trial is to evaluate whether following a multimodal prehabilitation program including physical exercise, nutritional support and psychological intervention during neoadjuvant chemotherapy in breast cancer…
- Trial name
- DIANA (NCT07107594)
- Testing
- Multimodal prehabilitation
- Where
- Spain
- Volunteers
- 214 people
- Sponsor
- Hospital Clinic of Barcelona
Cancer
Does Prehabilitation Improve Exercise Performance and Insulin Resistance After Surgery for Oesophago-gastric Cancer?
The purpose of this study is to evaluate the effect of a multimodal pre-operative prehabilitation programme during neo-adjuvant therapy on cardiopulmonary exercise performance and insulin resistance prior to resection for…
- Trial name
- NCT02950324
- Testing
- Prehabilitation, Standard care
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Improve Quality of Life
Exercise Program After Total Hip and Knee Replacement: a Randomized Controlled Trial
Randomized controlled trial. Patients will be enrolled at the moment of the pre-surgery assessment after verifying the inclusion/exclusion criteria and signing written informed consent.
- Trial name
- PAIR (NCT04761367)
- Testing
- Physical activity. Physical Activity program is performed in a group in a gym
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Istituto Ortopedico Rizzoli
Stroke
SPiRE Maestro Hand Exoskeleton for Rehabilitation Post Stroke
The research team will develop a novel training tool to improve finger joint coordination, to address the unmet need in the current rehabilitation, thereby enhancing hand function and contributing to improved independence and…
- Trial name
- NCT04978467
- Testing
- Exoskeleton
- Where
- United States
- Sponsor
- VA Office of Research and Development
Advanced Lung Non-Small Cell Carcinoma
Tai-Chi and Aerobic Exercise to Improve Emotional Symptom Cluster in Late-stage Lung Cancer Patients
The goal of this randomized controlled trial is to investigate the effects of Tai-Chi and aerobic exercise on the emotional symptom cluster, and the underlying mechanism of that cluster, in late-stage lung cancer patients.
- Trial name
- NCT05778708
- Testing
- Tai-Chi intervention, Aerobic exercise intervention
- Where
- Hong Kong
- Volunteers
- 318 people
- Sponsor
- The University of Hong Kong
Problematic Internet Use
Group-based IMPROVE Therapy for Problematic Internet Use in University Students
Problematic internet use (PIU) is a growing behavioral health concern among university students. This study aims to evaluate the effectiveness and psychological mechanisms of "IMPROVE," a manualized, multimodal group-based…
- Trial name
- IMPROVE-PIU (NCT07434778)
- Testing
- IMPROVE Program, Digital Psychoeducation Newsletters
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Sir Run Run Shaw Hospital
Ovarian Cancer
Targeted Physical Activity to Improve Mobility and Falls Risk in Women Living With Ovarian Cancer
This study will explore the feasibility (suitability), efficacy (research-setting outcomes), and participant satisfaction of a virtually-supervised 12-week exercise and diet intervention for women with ovarian cancer.
- Trial name
- BE-BALANCED (NCT04911114)
- Testing
- Be-Balanced
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Patent Foramen Ovale
Does Patent Foramen Ovale Closure Improve Exercise Capacity & Prevent Blood Flow Through Intrapulmonary Shunt
The overarching goal of this study is to examine cardiopulmonary and respiratory physiology pre and post PFO/ASD closure in patients who are undergoing surgical closure of their PFO/ASD.
- Trial name
- PFO CLOSE (NCT03904290)
- Testing
- PFO Closure
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Oregon
Lymphoblastic Leukemia, Cancer Survivors
Exercise Training and NR Supplementation Trial to Improve Fitness in AYA HCT Survivors
This will be a randomized, placebo-controlled trial with a 2x2 factorial design testing the effects of an NAD+ precursor (NR) and exercise on skeletal muscle quality and VO2max in AYA HCT survivors.
- Conditions
- Lymphoblastic Leukemia, Cancer Survivors, Aplastic Anemia, Myelodysplastic Syndromes
- Trial name
- IAMFIT (NCT05194397)
- Testing
- Nicotinamide Riboside, Exercise Intervention
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Children's Hospital of Philadelphia
Stroke Patients, Stroke
Feasibility of a Physiotherapy Programme, With Integrated telerehabIlitation to Increase Rehabilitation Time and Improve Motor Function
About two thirds of people after stroke have some level of disability. Rehabilitation helps to reduce disability and supports people to return to a meaningful life.
- Trial name
- PRACTISE (NCT06871878)
- Testing
- PRACTISE Physiotherapy Intervention
- Where
- 4 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Glasgow Caledonian University
Sedentary Lifestyle
Way to Be Active III (Framing Incentives)
Employers are increasingly looking for opportunities to motivate sedentary employees to become more physically active. Workplace walking programs have had mixed success and typically show most improvement among participants that…
- Trial name
- NCT02030119
- Testing
- Financial Incentives, Daily feedback
- Where
- United States
- Volunteers
- 281 people
- Sponsor
- University of Pennsylvania