Clinical trials: Improvement in Function
Relapsing-Remitting Multiple Sclerosis
A fMRI(Functional Magnetic Resonance Imaging) Research Study to Learn More About Multiple Sclerosis and Individuals Potentially Experiencing Memory Difficulties
The purpose of this study is to determine if medication designed to improve memory will help patients with Multiple Sclerosis (MS) who are experiencing memory problems using fMRI to track brain activity.
- Trial name
- NCT00315367
- Testing
- Donepezil HCI (drug)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Neurognostics
Dry Eye Disease (DED)
Randomized Single Center Study to Evaluate Tolerability, Symptoms, and Visual Functional Outcomes With the Use of OTC Lubricating Eye Drops in Subjects With Dry Eye Disease
A study to evaluate the effect of over- the- counter (OTC) lubricating eye drops on tolerability, symptoms and visual outcomes in patients with dry eye disease (DED)
- Trial name
- NCT07676084
- Testing
- Preservative Free Polyethylene glycol 400 0.25%, Propylene Glycol (0.6%), Carboxymethylcellulose sodium 0.5%, Glycerin 1.0%, Polysorbate 80 0.5%
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Andover Research Eye Institute
Emphysema
Pulmonx Endobronchial Valves Used in Treatment of Emphysema (LIBERATE Study)
The purpose of this research is to study an investigational medical device that is designed to produce lung volume reduction in diseased areas of the lungs in patients with severe emphysema.
- Trial name
- LIBERATE (NCT01796392)
- Testing
- EBV, Optimal Medical Management
- Where
- 23 sites in United States, Brazil and 2 more
- Volunteers
- 190 people
- Sponsor
- Pulmonx Corporation
Prostatic Hyperplasia
Male Sexual Health Questionnaire (MSHQ) - Sexual Function Study
Primary: To assess improvement in ejaculation from baseline to the end of treatment (Week 12 or premature withdrawal) with Alfuzosin 10mg OD, using MSHQ score.
- Trial name
- NCT00427882
- Testing
- ALFUZOSIN
- Where
- South Korea
- Volunteers
- 125 people
- Sponsor
- Handok Inc.
People Aged 55-70 Years
The Effect of Probiotics on the Improvement of Digestive Function and Well-being in the Elderly
To evaluate the effectiveness and safety of the use of probiotics as food supplements compared to placebo in improving digestive function and well-being in older adults.
- Trial name
- NCT06648590
- Testing
- Probiotic
- Where
- China
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Osteoarthritis
The Assessment of TCI633 Probiotics on Pain Relief and Functional Improvement in Osteoarthritis
To assess TCI633 probiotics on pain relief and functional improvement in osteoarthritis
- Trial name
- NCT04267432
- Testing
- TCI633, Type 2 collagen
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- TCI Co., Ltd.
Protruded Disk
CLARIX™ 100 & CLARIX CORD 1K for Discectomy Patients
The purpose of the study is to evaluate the efficacy of CLARIX™ 100 and CLARIX™ CORD 1K as a tissue barrier when used as an annular patch in discectomy patients with low back \& leg pain when compared to traditional discectomy…
- Trial name
- NCT03113786
- Testing
- CLARIX™100, CLARIX CORD 1K
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Amniox Medical, Inc.
Hematologic Disease, Hemophilia A
BAY14-2222 Prophylaxis and Joint Function Improvement (Adults)
The purpose of the study is to evaluate the effect of prophylactic treatment on the number of joint bleeds and quality of life in severe hemophilia A subjects compared to on-demand treatment in a one-group two-treatment schedule…
- Trial name
- NCT00586521
- Testing
- Kogenate (BAY14-2222)
- Where
- 11 sites in United States, France and 3 more
- Volunteers
- 20 people
- Sponsor
- Bayer
Healthy
A Study to Assess Safety and Improvement in Skin Barrier After Using 2 Facial Sunscreens in Adults With Sensitive Skin
The purpose of this trial is to evaluate 1) the dermatological tolerability of 2 facial sunscreens after 21 (+2) days of use under normal conditions on the half face by adult subjects with sensitive skin, 2) Compare the efficacy…
- Trial name
- NCT06243627
- Testing
- Sunscreen C Color 2.0 SPF 70, Sunscreen C Color 3.0 SPF 70, Sunscreen M Very Light SPF 50
- Where
- Brazil
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Chronic Obstructive Pulmonary Disease
Evaluation of Symbicort® Turbuhaler® (Budesonide/Formoterol) in Chronic Obstructive Pulmonary Disease (COPD)
This non-interventional study is to analyse the therapeutic effectiveness in patients with severe COPD following a generally accepted 12-week treatment period with Symbicort Turbuhaler, which could anyhow be shortened or extended…
- Trial name
- NCT00837629
- Volunteers
- 743 people
- Sponsor
- AstraZeneca
Gastrointestinal Function
Probiotics and Non-Organic Gastrointestinal Improvement
To verify the improvement of gastrointestinal function in patients with non-organic gastrointestinal dysfunction after 4 weeks of intervention with compound probiotics.
- Trial name
- NCT07081100
- Testing
- Probiotic group
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Ischemic Stroke
A Study to Evaluate the Efficacy and Safety of TF0023 Spray on Subjects With Ischemic Strokes
This is a phase 2, multicenter, randomized, double-blind (within dose), placebo controlled, parallel-group, dose-range finding study to evaluate the efficacy and safety of TF0023 spray versus placebo in functional improvement of…
- Trial name
- TF0023 (NCT02785120)
- Testing
- TF0023
- Where
- 24 sites in United States
- Volunteers
- 225 people
- Sponsor
- Techfields Inc
Osteoarthritis
Gait and Functional Improvement in Total Knee Arthroplasty With the Use of Verasense for Soft Tissue Balancing
The primary objectives of this study are to understand the effects of soft-tissue balancing on Gait, function and rehabilitation potential after sensor-assisted Total Knee Arthroplasty and correlate Intra-operative subjective…
- Trial name
- NCT02290119
- Testing
- Sensor-assisted TKR (Verasense), Control - Without the use of Verasense
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Orthosensor, Inc.
Schizophrenia
NIS to Observe Improvement in Global Assessment of Functioning in Patients With Schizophrenia
The purpose of the study is to monitor the general functional changes among patients with schizophrenia, treated with atypical antipsychotics dosed once daily for a period of 6 months.The primary study objective is to compare…
- Trial name
- NCT00833456
- Where
- 14 sites in Slovenia
- Volunteers
- 106 people
- Sponsor
- AstraZeneca
Abdominal Pain/ Discomfort, Slightly Constipation
Effect of Perilla Extract on Improvement on Gastrointestinal Discomfort
In the current study the effects of proprietary Perilla frutescens leaf extract in comparison to Maltodextrin, a fully digestible carbohydrate (placebo control), on gastrointestinal discomfort and bowel function were…
- Trial name
- NCT01931930
- Testing
- Perilla extract, Maltodextrin
- Where
- Germany
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Amino Up Chemicals Co., Ltd.
Mild Dementia
The Efficacy and Safety of tDCS in Patients With Mild Dementia
This study evaluated the effectiveness and safety of improving Mild Dementia by applying tDCS for 26 weeks to patients with Mild Dementia.
- Trial name
- NCT05495113
- Testing
- YMS-201B (Device: Mind STIM)
- Where
- 2 sites in South Korea
- Volunteers
- 118 people
- Sponsor
- Ybrain Inc.
Irritable Bowel Syndrome
IQP-CL-101 in IBS Management
After 2 weeks of run-in period, subjects are randomized to either IQP-CL-101 or a matching placebo. Over 8 weeks, the subjects are monitored for improvements in IBS symptoms
- Trial name
- NCT01774825
- Testing
- IQP-CL-101
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Degenerative Sacroiliitis, Sacroiliac Disorder
Sacroiliac Joint Fusion Intervention For Mobility, Pain Relief, and Lasting Improvement in Functional Recovery "SIMPLIFY"
The purpose of this study is to determine the clinical efficacy of The Trellis SI Joint Fusion System in unilateral sacroiliac (SI) joint fusion surgeries.
- Trial name
- SIMPLIFY (NCT07849244)
- Testing
- TRELLIS SI Joint Fusion System
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- OrthoFundamentals, LLC
Gastrointestinal Microbiome
Effects of Vigiis 101-LAB on a Healthy Populations' Gut Microflora
This clinical trial was conducted as part of the "Methods for Evaluating the Improvement of Gastrointestinal Function in Health Food" announced by the Department of Health, DOH (currently known as Ministry of Health and Welfare…
- Trial name
- NCT04088474
- Testing
- Vigiis 101-LAB
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- SunWay Biotech Co., LTD.
Deglutition Disorders
Clinical Trial on the Safety and Efficacy of Optimized Transcranial Direct Current Stimulation for the Swallowing Function in Patients With Post-Stroke Dysphagia
The goal of this clinical trial is to evaluate whether the application of optimized transcranial direct current stimulation is more effective compared to sham stimulation for temporary improvement of swallowing function in…
- Trial name
- NCT06305949
- Testing
- Optimized transcranial Direct Current Stimulation
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- NEUROPHET