Clinical trials: Improvement in Function
Asthma
Efficacy and Safety of CHF 1535 200/6µg in Not Adequately Controlled Asthmatic Patients
Primary objective To show the superiority of CHF 1535 (BDP/FF) pMDI (800/24 μg per day) over BDP HFA pMDI (800 μg per day) in terms of change from baseline to the entire treatment period in average pre-dose morning peak…
- Trial name
- FORCE (NCT01577082)
- Testing
- CHF1535 200/6 µg pMDI, BDP HFA 100 µg pMDI
- Where
- 66 sites in Bulgaria, Czechia and 7 more
- Volunteers
- 542 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Schizophrenia
Safety and Efficacy Study of Paliperidone Extended Release (ER) Among Thai Schizophrenia Participants
The purpose of this study is to evaluate the effectiveness and safety of paliperidone extended release (ER) treatment in Thai schizophrenia (psychiatric disorder with symptoms of emotional instability, detachment from reality…
- Trial name
- PRESENT (NCT01387542)
- Testing
- Paliperidone extended release (ER)
- Where
- 2 sites in Thailand
- Volunteers
- 40 people
- Sponsor
- Janssen-Cilag Ltd.,Thailand
Vision, Low
eSight Eyewear Quality of Life and Efficacy Study
The "eSight Quality of Life and Efficacy Study" (eQUEST) is a prospective cohort study intended to demonstrate the functional vision and Quality of Life (QoL) improvement provided by eSight Eyewear to persons with significant…
- Trial name
- eQUEST (NCT02616900)
- Testing
- eSight Eyewear
- Where
- 6 sites in United States, Canada
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- eSight Corporation
Neuromuscular Diseases
Effectiveness of Respiratory Physiotherapy in Children With Neuromuscular Disease
The main objective of this study is to determine whether the Respiratory Physiotherapy allows improvement or maintenance of respiratory function in children with Neuromuscular Diseases, against respiratory deterioration that…
- Trial name
- NCT02743702
- Testing
- RESPIRATORY PHYSIOTHERAPY, USUAL THERAPIES
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- University of Seville
Obesity, Heart Failure, Diastolic
Improving Metabolic Health in Patients With Diastolic Dysfunction
The purpose of this study is to determine whether 1 year of supervised exercise training in obese individuals at high risk for developing HF, incorporating high intensity interval training (HIIT) two to three times per week in…
- Conditions
- Obesity, Heart Failure, Diastolic, Metabolic Syndrome
- Trial name
- MTG (NCT03448185)
- Testing
- High intensity exercise, Omega-3 fish oil, Yoga
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Psychogenic Dyspepsia
Clinical Improvement and in Quality of Life-Functional Dyspepsia-
Functional dyspepsia (FD)is defined as the presence of symptoms thought to originate in the gastroduodenal region with no evidence of structural disease that is likely to explain the symptoms.
- Trial name
- NCT01802710
- Testing
- Psychological support, No intervention
- Where
- Spain
- Volunteers
- 158 people
- Sponsor
- Hospital Galdakao-Usansolo
Subacromial Bursitis, Shoulder Pain
Relationship to Dose of Triamcinolone Acetonide and Methylyprednisolone to Improvement in Subacromial Bursitis
It is currently unknown whether or not the improvement in pain and function related to a "steroid shot" for shoulder pain due to subacromial bursitis is important.
- Trial name
- NCT02242630
- Testing
- Methylprednisolone, 20 mg, Methylprednisolone, 40 mg, Triamcinolone, 20 mg
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Keesler Air Force Base Medical Center
Minimal Hepatic Encephalopathy
Study of Lactulose in Children With Chronic Liver Disease
Pediatric patients with chronic liver disease may have Minimal Hepatic Encephalopathy(MHE)which can cause changes in behavior,intelligence and neurological function.By utilizing cognitive and developmental testing we will…
- Trial name
- MHE (NCT00811434)
- Testing
- Lactulose
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Indiana University
Emphysema
Pulmonx Endobronchial Valves Used in Treatment of Emphysema (LIBERATE Study)
The purpose of this research is to study an investigational medical device that is designed to produce lung volume reduction in diseased areas of the lungs in patients with severe emphysema.
- Trial name
- LIBERATE (NCT01796392)
- Testing
- EBV, Optimal Medical Management
- Where
- 23 sites in United States, Brazil and 2 more
- Volunteers
- 190 people
- Sponsor
- Pulmonx Corporation
Back Pain Lower Back
Improvement in Pain,Function and HRQoL ( Health Related Quality of Life) in Subacute Low Back Pain: A Controlled Clinical Trial of Exercise vs NSAIDs (Nonsteroidal Antiinflammatory)
Our clinical trial has the purpose to evaluate the effectiveness in reducing pain and improving function and quality of life during a 6-months follow-up of a therapeutic exercise program compared to pharmacological treatment with…
- Trial name
- DLSEA (NCT01374269)
- Testing
- Exercise program, NSAID (Nonsteroidal anti-inflammatory drugs)
- Where
- 2 sites in Colombia
- Volunteers
- 90 people
- Sponsor
- Grupo Rehabilitacion en Salud
Osteoarthritis
Time-dependent Improvement of Functional Outcome Following Oxford Medial Unicondylar Knee Replacement
The objective of this prospective study is to determine (1) the time course of patient-relevant functional outcome evaluated by the Knee injury and Osteoarthritis Outcome Score (KOOS) and (2) the time course of range of motion…
- Trial name
- NCT01032538
- Where
- 3 sites in Norway
- Volunteers
- 99 people
- Sponsor
- Vestre Viken Hospital Trust
Alzheimer's Disease
Endothelial Facilitation in Alzheimer's Disease
Purpose of the study: Patients with mild Alzheimer's Disease will be given three different drugs over a 4-month period to try to increase the blood flow to their brains, and improve blood vessel and brain function.
- Trial name
- NCT01439555
- Testing
- Simvastatin, L-Arginine, Tetrahydrobiopterin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Massachusetts, Worcester
Healthy Adults With Subjective Memory Complaints
Effects of HX106 on Improvement in Cognitive-Bio-Markers of Memory Function
The objectives of the current study are to evaluate the efficacy and safety of HX106 in healthy adults with subjective memory complaints for improving cognitive and neurobiolgoical markers of memory.
- Trial name
- NCT01956097
- Testing
- HX106 590mg, HX106 1180mg
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Hypogonadism, Male
Anastrazole and Clomiphene to Evaluate Hypogonadal Symptoms and Erectile Function
This study evaluates anastrazole and clomiphene in the improvement in hypogonadal symptoms and erectile function. Each subject will receive Anastrazole 1 mg/day, clomiphene 25 mg/day and placebo in randomized schedule of 8 week…
- Trial name
- CAP (NCT03933618)
- Testing
- Anastrozole 1mg, Clomiphene Citrate 25mg
- Volunteers
- 24 people
- Sponsor
- Albany Medical College
Hematologic Disease, Hemophilia A
BAY14-2222 Prophylaxis and Joint Function Improvement (Adults)
The purpose of the study is to evaluate the effect of prophylactic treatment on the number of joint bleeds and quality of life in severe hemophilia A subjects compared to on-demand treatment in a one-group two-treatment schedule…
- Trial name
- NCT00586521
- Testing
- Kogenate (BAY14-2222)
- Where
- 11 sites in United States, France and 3 more
- Volunteers
- 20 people
- Sponsor
- Bayer
Sarcoma
Progressive Resistance Training for the Improvement of Physical Function
This trial studies how well progressive resistance training works in improving the physical function of sarcoma survivors. Treatments for sarcoma can cause side effects such as fatigue, muscle loss, and weakness, which can…
- Trial name
- NCT04247425
- Testing
- Exercise Counseling, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- OHSU Knight Cancer Institute