Clinical trials: Impulse-Control Disorders
Pathologic Skin Picking, Neurotic Excoriation
N-Acetyl Cysteine in Pathologic Skin Picking
The goal of the proposed study is to evaluate the comparative efficacy of N-acetyl cysteine to placebo in pathologic skin picking.
- Conditions
- Pathologic Skin Picking, Neurotic Excoriation, Psychogenic Excoriation, Dermatillomania
- Trial name
- NCT01063348
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Chicago
Pathological Gambling
Topiramate in the Treatment of Pathological Gambling
This study will assess the efficacy of topiramate in the treatment of pathological gambling. Pathological gambling (PG) is a debilitating disorder, generally leading to severe personal, familial, financial, social, and…
- Trial name
- NCT00245583
- Testing
- Topiramate
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Trichotillomania
N-Acetyl Cysteine in Trichotillomania
This is a 12-week, double-blind study of N-Acetyl Cysteine in the treatment of trichotillomania
- Trial name
- NCT00354770
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Chicago
Impulse Control Disorder, Parkinson Disease
Naltrexone for Impulse Control Disorders in Parkinson's Disease
This study will evaluate the effectiveness of naltrexone in reducing ICD symptoms in Parkinson's disease patients taking a dopamine agonist.
- Trial name
- NCT01052831
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Pathological Gambling, Gambling Disorder
Milk Thistle in Pathological Gambling
The goal of the proposed study is to evaluate the efficacy and safety of silymarin in individuals with gambling disorder. The hypothesis to be tested is that silymarin will be more effective and well tolerated in subjects with…
- Trial name
- NCT02337634
- Testing
- Milk Thistle
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Chicago
Trichotillomania, Obsessive Compulsive Disorder
Marinol in Trichotillomania or Obsessive Compulsive Disorder
The goal of the proposed study is to evaluate the efficacy and safety of dronabinol in individuals with obsessive-compulsive disorder (OCD) or the obsessive-compulsive spectrum disorders, trichotillomania (TTM) or pathological…
- Trial name
- NCT01093976
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Chicago
Intermittent Explosive Disorder
Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Intermittent Explosive Disorder
This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate AVP-786 for the treatment of Intermittent Explosive Disorder (IED).
- Trial name
- NCT03420222
- Testing
- AVP-786
- Where
- 9 sites in United States
- Volunteers
- 10 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder)
Epidiolex in Obsessive Compulsive Disorder and Related Disorders
The primary objective of the proposed study is to evaluate the safety and efficacy of Epidiolex (cannabidiol) in adults with obsessive compulsive and related disorders (OCRDs).
- Conditions
- Obsessive-Compulsive Disorder, Trichotillomania (Hair-Pulling Disorder), Tourette Syndrome, Hoarding Disorder
- Trial name
- NCT04978428
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Chicago
Trichotillomania
Feasibility Study for Treating Trichotillomania With Wearable Device and App System
Trichotillomania is characterized by recurrent hair pulling resulting in hair loss causing significant distress and impairment which persists despite repeated attempts to stop.
- Trial name
- NCT04241120
- Testing
- Device and app system designed for participant to self-administer Habit Reversal Training, Reminder bracelet control condition
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- HabitAware Inc.
Atrial Fibrillation
Topera C-FIRM Registry
This is a control registry to the E-FIRM registry to track conventional atrial fibrillation (AF) procedures in terms of clinical usage, handling, and the safety and effectiveness for the treatment of symptomatic atrial…
- Trial name
- NCT02407249
- Where
- 9 sites in Germany, Netherlands
- Volunteers
- 73 people
- Sponsor
- Abbott Medical Devices
Pathological Gambling
Dopamine Responsivity in Gamblers
This study deals with how people decide between rewards of different value. The investigators want to understand how the brain's dopamine system impacts this kind of decision making.
- Trial name
- NCT02772978
- Testing
- Tolcapone
- Volunteers
- 19 people
- Sponsor
- University of California, San Francisco
Pathological Gambling
Acamprosate in the Treatment of Pathological Gambling
The purpose of this study is to see whether acamprosate (Campral) will curb the desire to gamble in people with pathological gambling disorder.
- Trial name
- NCT00571103
- Testing
- acamprosate
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Intermittent Explosive Disorder, Childhood Aggression
Intuniv vs Placebo in the Treatment of Childhood Intermittent Explosive Disorder
Children with explosive aggression are often rejected by their peers, placed in special classroom, and contribute to family discord. When psychotherapy and family therapy is unsuccessful, medications are often used.
- Conditions
- Intermittent Explosive Disorder, Childhood Aggression, Oppositional Defiant Disorder, Attention Deficit Disorder
- Trial name
- NCT02048241
- Testing
- Parent Management Training, Intuniv
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- New York State Psychiatric Institute
Pathological Gambling
Investigation of Naltrexone for Pathological Gambling
The investigators plan to investigate the safety, tolerability, and efficacy of the opioid antagonist naltrexone in Pathological Gambling.
- Trial name
- NCT01057862
- Testing
- Naltrexone
- Where
- 3 sites in United States
- Volunteers
- 9 people
- Sponsor
- Yale University
Compulsive Buying
Memantine Treatment of Compulsive Buying
This is an 8-week, open-labe study of memantine in the treatment of compulsive buying.
- Trial name
- NCT00830375
- Testing
- Memantine
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Minnesota
Trichotillomania
Awareness Enhancement and Monitoring Device for Treatment of Trichotillomania
The goals of the study are to further design, develop, and test an awareness enhancement and monitoring device, which will be used in the self-awareness training and general treatment of patients with compulsive hair-pulling…
- Trial name
- NCT01654523
- Testing
- Awareness Enhancement and Monitoring Device for Treatment of Trichotillomania
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Michigan
Modified DECIDE Intervention, Treatment as Usual Care Group
The DECIDE Parent-Provider Intervention
The DECIDE Parent-Provider Intervention is designed to support parents caring for adolescents who are receiving treatment for Disruptive, Impulse-Control, and Conduct disorders.
- Trial name
- NCT04445155
- Testing
- Modified DECIDE Parent and Provider Intervention
- Where
- 5 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Indiana University
Obsessive Compulsive Disorder, Trichotillomania
Developing Effective Response Inhibition Training for Symptom Relief in OCD and Trichotillomania
Obsessive-compulsive disorder (OCD) and its related disorders (e.g., trichotillomania) are characterized by the marked difficulty in inhibiting unwanted or inappropriate responses.
- Trial name
- NCT02059980
- Testing
- Response inhibition training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Wisconsin, Milwaukee
Pathological Gambling
Testing Resources: Manual and Webinar Guided Treatment vs. Manual Guided Treatment
Research specific to women's gambling treatment needs is limited but suggests a critical need for women sensitive options and reduced barriers to access.
- Trial name
- NCT01743092
- Testing
- Webinar, Tutuorial workbook
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- Centre for Addiction and Mental Health
Delayed Sleep Phase
Delayed Sleep Timing in Teens Study
This study will (1) comprehensively characterize the substance use disorder (SUD) risk profile associated with adolescent Delayed Sleep Phase (DSP), and (2) probe whether SUD risk is diminished by altering sleep/circadian timing.
- Trial name
- NCT03806296
- Testing
- Increase morning bright light, Decrease evening blue light, Sleep scheduling
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh