Clinical trials: In Vitro Fertilisation Outcome, active
Subclinical Hypothyroidism, Infertility
Levothyroxine Treatment and IVF Outcomes in Women With Subclinical Hypothyroidism: A Target Trial Emulation
Subclinical hypothyroidism (SCH) is defined by elevated thyroid-stimulating hormone (TSH) with normal free thyroxine (fT4) levels.
- Conditions
- Subclinical Hypothyroidism, Infertility, Assisted Reproductive Technology, In Vitro Fertilization (IVF)
- Trial name
- LESI (NCT07257250)
- Where
- 2 sites in Vietnam
- Volunteers
- 900 people
- Sponsor
- Mỹ Đức Hospital
Infertility
In Vitro Fertilisation Versus Intracytoplasmic Sperm Injection in Patients Without Severe Male Factor Infertility
Over recent decades, the use of intracytoplasmic sperm injection (ICSI) has increased, even among patients without severe male factor infertility.
- Trial name
- INVICSI (NCT04128904)
- Testing
- IVF, ICSI
- Where
- 6 sites in Denmark
- Volunteers
- 824 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
IVF
Ubiquinone vs. Ubiquinol Supplementation
The objective of this study is to determine if ubiquinol will result in improved reproductive outcomes in older women at a reduced oral dose compared to current standard treatment with ubiquinone.
- Trial name
- NCT06555575
- Testing
- Ubiquinone 200 Mg Oral Capsule, Ubiquinol 100 MG Oral Capsule
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trio Fertility
Frozen Embryo Transfer (FET), Assisted Reproductive Techniques
Direct Warming Frozen Embryo Transfer Outcomes in Assisted Reproductive Technology
The goal of this clinical trial is to evaluate whether the direct warming method for frozen embryo transfers (FET) can improve live birth and pregnancy outcomes in women aged 18-45 undergoing IVF treatments.
- Conditions
- Frozen Embryo Transfer (FET), Assisted Reproductive Techniques, In Vitro Fertilization (IVF), Cryopreservation of Embryos
- Trial name
- DW-FET-RCT (NCT06741748)
- Testing
- Direct Warming Method, Conventional Multi-step Thawing Method
- Where
- 3 sites in Hong Kong, United Kingdom
- Volunteers
- 578 people
- Sponsor
- Chinese University of Hong Kong
IVF Outcome
Trigger Timing in Ovarian Stimulations
The gonadotrophin-releasing hormone (GnRH) antagonist protocol is widely used in in vitro fertilisation (IVF) for its flexibility and ability to reduce the risk of ovarian hyperstimulation syndrome (OHSS).
- Trial name
- NCT04163133
- Testing
- 1-2 days later trigger than regular timing
- Where
- China
- Volunteers
- 834 people
- Sponsor
- Peking University Third Hospital
Autoimmune Diseases
Research of Predictive Factors of in Vitro Fertilization (IVF) Outcome AI-IVF Study
Infertility is the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected intercourse, while subfertility means a delay in achieving pregnancy.
- Trial name
- AI-IVF (NCT06872294)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Polygenic Score
Polygenic Embryo Selection
This study will evaluate whether IVF success rates after PRS-based embryo selection differ from those after morphology-based embryo selection, and whether polygenic disease risk correlates with embryo morphology.
- Trial name
- NCT07841769
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Nucleus Genomics Inc.
Ovarian Aging, In Vitro Fertilisation (IVF) Treatment
Follicular Fluid microRNAs in Ovarian Aging and Reproduction
The purpose of this study is to investigate the role of exosomal microRNAs (miRNAs) in follicular fluid (FF) as biomarkers of ovarian aging and predictors of in vitro fertilization (IVF) outcomes.
- Conditions
- Ovarian Aging, In Vitro Fertilisation (IVF) Treatment, InVitro Fertilization, In Vitro Fertilization Outcome
- Trial name
- NCT07214246
- Testing
- No Interventions
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Central Florida
Preterm Birth, Gestational Diabetes Mellitus (GDM)
Evaluation of Maternal and Neonatal Outcomes in Women Are Conceived Through Assisted Reproductive Technology Compared to Other Fertility Treatments and Naturally Conceived Women: It is a Retrospective Cohort Study Conducted Over a 5-year Period at a Fertility Center in a Lebanese Hospital
Background: The number of couples experiencing difficulties conceiving and seeking treatment for infertility has increased dramatically over time.
- Conditions
- Preterm Birth, Gestational Diabetes Mellitus (GDM), Gestational Hypertension
- Trial name
- non (NCT06836843)
- Testing
- Since this is an observational study rather than an interventional study, the exposure type refers to all potential factors influencing pregnancy both before and during pregnancy
- Where
- Lebanon
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Lebanese University
Infertility, Assisted Reproductive Technology Outcomes
The Impact of Having a Tattoo on Fertility Treatment Outcome
Tattoos are increasingly common among women of reproductive age, yet their potential systemic inflammatory effects and impact on fertility treatment outcomes are unknown.
- Trial name
- NCT07405879
- Where
- Canada
- Volunteers
- 328 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre