Clinical trials: In Vitro Fertilization
Diminished Ovarian Reserve, IVF
Study of G-CSF for DOR in Patients Undergoing IVF
Diminished ovarian reserve (DOR) is defined by reduced follicle counts in women, associated with decreased fertility and lower success rates with In Vitro Fertilization (IVF).
- Conditions
- Diminished Ovarian Reserve, IVF, G-CSF, Granulocyte Colony Stimulating Factor
- Trial name
- NCT07871825
- Testing
- Neupogen 300 μg subcutaneous injection, Subcutaneous injections of a saline solution
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Center for Human Reproduction
Fertilization in Vitro, Pregnancy Loss
IVF Failure and Pregnancy Loss on Couples' Psychological Stress
The goal of this observational study is to learn about The purpose of this study was to compare the psychological differences between couples after IVF transplant failure and IVF pregnancy loss, including the differences in…
- Conditions
- Fertilization in Vitro, Pregnancy Loss, Psychological Stress, Post-traumatic Stress
- Trial name
- NCT06385444
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The First Hospital of Jilin University
Infertility
Individualization of Ovarian Stimulation Using AMH Maximizes the Benefits and Minimizes Complications and Risks
The purpose oh the study is to determine the usefulness of anti-Mullerian hormone (AMH) to identify women at risk of excessive and poor response in controlled ovarian stimulation (COS) for in vitro fertilization (IVF), and the…
- Trial name
- NCT01887652
- Testing
- conventional ovarian stimulation, individualized ovarian stimulation
- Where
- Brazil
- Volunteers
- 250 people
- Sponsor
- ANDROFERT - Clinica de Andrologia e Reproducao Humana
Poor Ovarian Response, Accupuncture
Acupuncture for Treatment of Patients With Poor Ovarian Response
This prospective randomized controlled trial is designed to investigate the effect of acupuncture on IVF/ICSI outcome in women with poor ovarian response.
- Trial name
- NCT04013984
- Testing
- Accupuncture
- Where
- Iran
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Early Abortion, Pregnancy Loss, Early
Comparison of Surgical Management of Early Pregnancy Loss by Suction Curettage Versus Hysteroscopy in Patients Undergoing In-vitro Fertilization (IVF)
Early pregnancy loss occurs in ~15% of pregnancies. The treatment options include surgical uterine evacuation by suction curettage, medical management with misoprostol, or conservative management without interventions.
- Trial name
- NCT07143578
- Testing
- Operative hysteroscopy using tissue removal device, suction curettage
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Infertility
Next Generation Sequencing Screening for Embryonic Ploidy Status
To evaluate the benefits of using next generation sequencing to assess embryonic aneuploidy. All viable blastocysts will be biopsied and cryopreserved for future transfer.
- Trial name
- nexgen (NCT02032264)
- Testing
- Comprehensive Chromosome Screening, Morphologically Best
- Where
- United States
- Volunteers
- 309 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
Subfertility
Prognostic Value of Progesterone for In Vitro Fertilization (IVF) Outcome
This observational study attempts to investigate the potential role of serum progesterone levels on the day of hCG administration (thus, the end of the follicular phase) on the probability of pregnancy, in patients undergoing IVF…
- Trial name
- PROG2 (NCT01067664)
- Where
- Greece
- Volunteers
- 130 people
- Sponsor
- Aristotle University Of Thessaloniki
Obesity, Infertility, Female
Improved Fertility After Exercise in Overweight/Obese Women
Overweight/obesity is associated with sub-fertility. The investigators will assess if regular exercise training prior to assisted fertilization will improve pregnancy rate in overweight/obese women referred to assisted…
- Trial name
- FertilEX (NCT01933633)
- Testing
- Exercise
- Where
- 2 sites in Norway
- Volunteers
- 18 people
- Sponsor
- Norwegian University of Science and Technology
Infertility
Phase III Study Comparing Efficacy and Safety of AFOLIA vs Gonal-f® RFF in Women (35 to 42) Undergoing IVF
The purpose of this study is to show that AFOLIA, a recombinant manufactured human follicle stimulating hormone (r-hFSH) has a similar efficacy and safety profile compared to Gonal-f® RFF.
- Trial name
- NCT01687712
- Testing
- AFOLIA, Gonal-f® RFF
- Where
- 22 sites in United States
- Volunteers
- 1,100 people
- Sponsor
- Fertility Biotech AG
Infertility
Use of Nitric Oxide Metabolites for Predicting Embryo Quality in In-Vitro Fertilization (IVF)
Improvements in In-Vitro Fertilization (IVF) outcomes have largely been due to the generation of excess embryos allowing for multiple embryo transfer.
- Trial name
- NCT00788619
- Testing
- Transfer of embryos on day 3 or day 5 after fertilization., Day 5 transfer
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Controlled Ovarian Stimulation
Trial to Assess the Pattern of Use of REKOVELLE® in Women Undergoing In Vitro Fertilisation (IVF) or Intracytoplasmic Sperm Injection (ICSI) Procedures in Routine Clinical Practice
Study designed to observe the usage patterns, efficacy and safety of REKOVELLE® in women naive to IVF and ICSI, undergoing their first Controlled Ovarian Stimulation (COS) treatment cycle with REKOVELLE® in routine clinical…
- Trial name
- NORSOS (NCT05499052)
- Testing
- REKOVELLE®
- Where
- 9 sites in Denmark, Norway and 2 more
- Volunteers
- 201 people
- Sponsor
- Ferring Pharmaceuticals
Infertility Implantation Failure
A Multicentre, Randomised, Double-blind, Placebo-controlled Proof of Concept Study to Compare the Efficacy and Safety of r-hLIF (Emfilermin) for Improving Embryo Implantation Following in Vitro Fertilization (IVF) and Embryo Transfer (ET) in Women With Recurrent Implantation Failure
The primary objective of the study was to provide further clinical and statistical evidence of the efficacy of r-hLIF, in comparison with placebo, administered during the luteal phase after IVF and ET for improving embryo…
- Trial name
- NCT00504608
- Testing
- Emfilermin, recombinant human leukemia inhibitory factor (r-hLIF)
- Volunteers
- 150 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Infertility
The Influence of Different Concentrations of Glucose in Culture Media on In Vitro Fertilization (IVF) Outcome of Sibling Oocytes
The importance of glucose in culture media on fertilization and embryo development is still controversial. Although it has been reported that glucose is essential for fertilization process and biosynthesis of membrane lipid and…
- Trial name
- NCT02066584
- Testing
- Sibling oocyte incubation
- Where
- Israel
- Volunteers
- 600 people
- Sponsor
- Hillel Yaffe Medical Center
Infertility, In Vitro Fertilization
Exploring the Effect of Footbaths on Increasing the Success Rates in Vitro Fertilization
To evaluate the effectiveness of warm-water footbaths in enhancing pregnancy rates during IVF and to explore the underlying mechanisms involved.
- Trial name
- NCT06624683
- Testing
- Intelligent footbath basin
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Infertility, Female, Endometrial Diseases
Effect of Different Ovarian Stimulation Protocols on Endometrial Receptivity
This study will assess the change in endometrial gene expression signature on the day of embryo transfer according to the type of exogenous gonadotropins administered.
- Trial name
- NCT03755973
- Testing
- CFA, rFSH, Fixed daily rFSH dosing protocol of 200-300 IU
- Where
- Portugal
- Volunteers
- 24 people
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Polycystic Ovary Syndrome IVF
OVERWEIGHT AND OBESITY ADVERSELY AFFECT IVF OUTCOMES IN WOMEN WITH PCOS
The effect of overweight and obesity on IVF outcomes is still questionable. The purpose of this study was to determine if overweight/obesity in women with PCOS were associated with an adverse IVF outcome compared to those with…
- Trial name
- NCT03120286
- Volunteers
- 146 people
- Sponsor
- Assiut University
Fertilization in Vitro
Plasticizers and in Vitro Fertilization Outcomes
To investigate the effect of Plasticizer metabolites concentration on the in vitro fertilization outcomes
- Trial name
- NCT03733912
- Testing
- Phthalate metabolites measurement
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Patients for In Vitro Fertilization(IVF)Treatment
Time-lapse Evaluation of Embryo Development After Stimulation With One of Two Different Gonadotrophins.
The primary purpose of the investigation is to identify differences in embryo development after follicle stimulation with two different gonadotrophins.
- Trial name
- NCT01345812
- Testing
- HP-HMG, recombinant FSH
- Where
- Denmark
- Volunteers
- 291 people
- Sponsor
- University of Aarhus
Infertility
What Embryoselection for What Chance of Success ? EmbryoSelect Study
The aim of the research is to evaluate the results of the first in vitro fertilization (IVF) attempt according to the type of embryo culture.
- Trial name
- EmbryoSelect (NCT04484181)
- Testing
- Embryo culture in time lapse technology (TLT), Embryo culture in conventional incubator
- Where
- 2 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Bordeaux
In Vitro Fertilization
Transvaginal vs Transabdominal Ultrasound Guided Embryo Transfer
Embryo transfer is the last step in the IVF process. it is now recognized that this step should be done carefully and that it affects success rates. in recent years, sonographic guidance appears to increase success rates.
- Trial name
- TVUSET (NCT00826332)
- Testing
- transabdominal ultrasound, transvaginal ultrasound
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Hadassah Medical Organization