Clinical trials: In-Vitro Fertilization
Pregnancy
Pregnancy and Neonatal Follow-up of Ongoing Pregnancies Established During Phase II Clinical Trials of Org 36286 (Study 38817)(P06054)(COMPLETED)
The objective of this trial was to evaluate whether Org 36286 treatment in any Phase IIa clinical development trial of Org 36286 for OI or COH in assisted reproductive treatment programs was safe for pregnant subjects and their…
- Trial name
- NCT00702195
- Testing
- Org 36286 (corifollitropin alfa), recFSH
- Volunteers
- 29 people
- Sponsor
- Organon and Co
Infertility
NuvaRing Versus Marvelon in the Coordination of In Vitro Fertilization Cycles
Presently, a long protocol in an In Vitro Fertilization (IVF) cycle, patients need to take Marvelon, a drug that inhibits the follicular development at the beginning of the cycle in order to better control and also plan the onset…
- Trial name
- NCT01638767
- Testing
- Contraceptives, Oral, Contraceptive, Vaginal ring
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- Clinique Ovo
Polycystic Ovary Syndrome
Study to Assess the Effect of Metformin Supplementation on IVF Outcome in Patients With Polycystic Ovarian Syndrome.
This study was performed to investigate the effects of metformin on controlled ovarian stimulation (COS), in vitro fertilization (IVF) outcomes, pregnancy outcomes, and comparison of serum and follicular fluid cytokines and…
- Trial name
- NCT03086005
- Testing
- Metformin
- Where
- South Korea
- Volunteers
- 24 people
- Sponsor
- Chung-Hoon Kim
Ovulation Induction, Infertility
An Open Label, Canadian Phase IIIb Study With Ovidrel in Ovulation Induction (OI) and Assisted Reproductive Technique (ART)
With the development of the recombinant gonadotrophins, the use of human source proteins for the production of hormones has become unnecessary.
- Trial name
- NCT01152866
- Testing
- Choriogonadotropin alpha (r-hCG)
- Volunteers
- 3 people
- Sponsor
- EMD Serono
Infertility
Antimullerian Hormone Versus Antral Follicle Count for Determination of Gonadotrophin Dosing in IVF
This is a prospective randomized trial to compare the use of AFC and serum AMH as the basis for gonadotrophin dosing in in-vitro fertilization treatment.
- Trial name
- NCT02739269
- Testing
- Serum AMH measurement, AFC measurement
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Infertility, Infertility (IVF Patients)
Growth Hormone and Dehydroepiandrosterone Role in Vitro Fertilization
The goal of this study is to evaluate the role of Somatropin and Dehydroepiandrosterone (DHEA) on ovarian reserve parameters and intracytoplasmic sperm injection (ICSI) outcome in poor ovarian responder.
- Trial name
- NCT07323329
- Testing
- Somatropin (4IU for 1 month) plus, folic acid 400 mcg per day., DHEA plus folic acid 400mcg per day, control group
- Where
- Egypt
- Volunteers
- 165 people
- Sponsor
- Beni-Suef University
Female Infertility
Impact of Clomiphene Citrate Administration During the Early Luteal Phase on Endocrine Profile in IVF Cycles
The purpose of this study is to evaluate the effect on LH levels of the 5-day CC administration during luteal phase in oocyte donors, to investigate whether the CC corrects the suppressed LH levels in the luteal phase and whether…
- Trial name
- CLOFA (NCT01791751)
- Testing
- Clomifene Citrate
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fundació Privada Eugin
In Vitro Fertilization
Immune Modulators and IVF
Exploring the immune mediators of early pregnancy prospectively may help to identify new early interventions that will increase the likelihood of success and help women make informed decisions regarding their pregnancies.
- Trial name
- NCT02626702
- Testing
- Observational
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Weill Medical College of Cornell University
Infertility, Poor Ovarian Reserve
Growth Hormone for Poor Responders in in Vitro Fertilization (IVF)
The purpose of this study is to determine if growth hormone given 4 weeks before as well as during a cycle of in vitro fertilization will improve outcomes in women who have had previous failure with IVF treatment cycles using…
- Trial name
- NCT01204840
- Testing
- Growth Hormone, Patch protocol
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ottawa Fertility Centre
Infertility, Recurrent Implantation Failure
Effect of Reproductive Tract Microbiota on Pregnancy Outcome in IVF/ICSI
A single center，observational cohort study to explore the relationship between reproductive tract microbiota and pregnancy outcome in the patients accepted IVF/ICSI.
- Conditions
- Infertility, Recurrent Implantation Failure, Recurrent Miscarriage
- Trial name
- NCT04293068
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
IVF Outcomes, Stress Levels
Virtual Reality Use in Assisted Reproductive Technology
The study will examine the effect of exposure to virtual reality on stress levels and pregnancy rates, in infertile women undergoing in vitro fertilization embryo transfer
- Trial name
- NCT04394962
- Testing
- Virtual reality
- Where
- Canada
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Dr cliff Librach
Pain
A Randomized Controlled Trial of Oral Acetaminophen for Analgesic Control After Transvaginal Oocyte Retrieval
Current standard of care is no pretreatment medications before the egg retrieval, and the investigators would like to evaluate if preoperative Tylenol improves procedure and post procedure pain control over the current practice…
- Trial name
- NCT02418182
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Infertility
The Impact of the SPIKES Protocol With IVF Patients
The purpose of this study is to determine if the utilization of the SPIKES protocol for delivering bad news is perceived to be more compassionate and effective than the current standard of care for IVF patients receiving negative…
- Trial name
- NCT04917445
- Testing
- Spikes-focused bad news protocol
- Where
- 2 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Boston IVF
PCOS, IVF
IVM Versus IVF in High Antral Follicle Count Patients
In vitro maturation (IVM) is postulated to be an alternative to conventional in vitro fertilization (IVF) to avoid ovarian hyperstimulation syndrome.
- Conditions
- PCOS, IVF, IVM
- Trial name
- NCT03405701
- Testing
- IVM, IVF
- Where
- Vietnam
- Volunteers
- 546 people
- Sponsor
- Mỹ Đức Hospital
Infertility
PREVenting-ENvIronment-Reprotoxic Exposures Before In Vitro Fertilization (PREVENIR-FIV)
The objective is to evaluate the effectiveness of an innovative personalized management strategy adapted to the level of environmental risk, in a population of infertile couples, eligible for assisted reproductive treatment (ART)…
- Trial name
- PREVENIR-FIV (NCT06100523)
- Testing
- Visioconsulation, self-assessment questionnaire, hair sampling
- Where
- France
- Volunteers
- 4,224 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
in Vitro Fertilization, Single Embryo Transfer
eSET or eDET Associated to PGT in IVF
In vitro fertilization (IVF) techniques have been improving performance recently and, nowadays, provide a live birth rate of around 25%.
- Conditions
- in Vitro Fertilization, Single Embryo Transfer, Preimplantation Genetic Diagnosis, Pregnancy
- Trial name
- SetDetPgt (NCT03758833)
- Testing
- preimplantation genetic test of embryo by new generation sequencing (NGS), Single embryo transfer, Double embryo tranfer
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo General Hospital
In Vitro Fertilization, Postoperative Recovery
Estrogen Levels and Postoperative Recovery in IVF Patients
This prospective observational study aims to evaluate the relationship between supraphysiologic serum estrogen levels and postoperative recovery quality in patients undergoing IVF procedures under general anesthesia.
- Conditions
- In Vitro Fertilization, Postoperative Recovery, Estrogens, Anesthesia Recovery Period
- Trial name
- NCT06925633
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Konya City Hospital
Obesity, Infertility, Female
Improved Fertility After Exercise in Overweight/Obese Women
Overweight/obesity is associated with sub-fertility. The investigators will assess if regular exercise training prior to assisted fertilization will improve pregnancy rate in overweight/obese women referred to assisted…
- Trial name
- FertilEX (NCT01933633)
- Testing
- Exercise
- Where
- 2 sites in Norway
- Volunteers
- 18 people
- Sponsor
- Norwegian University of Science and Technology
Virtual Reality Therapy, Fertilization in Vitro
Effectiveness of Hypnosis Via Virtual Reality During Oocyte Retrieval
This study compares hypnosis via virtual reality to sedation with commonly used intravenous anesthetic agents (propofol and remifentanil) during oocyte retrieval.
- Conditions
- Virtual Reality Therapy, Fertilization in Vitro, Propofol, Remifentanil
- Trial name
- NCT05244538
- Testing
- Virtual reality distraction, Propofol-remifentanil sedation
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Erasme University Hospital
Administration of Increased Dose of GnRH Antagonist for Coasting for Decreasing the Risk for Ovarian Hyperstimulation Syndrome( OHSS)
Administration of Increased Dose of GnRH Antagonist for Coasting for Decreasing the Risk for Ovarian Hyperstimulation Syndrome( OHSS)
Coasting is one of the means to reduce the risk of OHSS for patients at risk for severe OHSS. During coasting gonadotrophin administration is withheld until serum E2 levels drop to a range considered safe.
- Trial name
- NCT01109888
- Testing
- Cetrotide
- Sponsor
- Wolfson Medical Center