Clinical trials: In-Vitro Fertilization
Infertility
Automated Sperm Selection
Intracytoplasmic sperm injection (ICSI) is one of the standard clinical treatments for infertility. ICSI involves the injection of a single sperm into an oocyte with a sharp micropipette.
- Trial name
- NCT05240469
- Testing
- Automated sperm selection software
- Where
- Canada
- Volunteers
- 330 people
- Sponsor
- Create Fertility Center
Repeated IVF Failure, Microbiota
The Role of the Physiological Endometrial Microbiota in Assisted Reproduction Outcomes
The goal of this observational study is to investigate the influence and contribution of the normal composition and balance of the endometrial microbiota on the achievement of embryo implantation and the maintenance of pregnancy…
- Trial name
- no exist (NCT07606053)
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Assisting Nature
Infertility, Frozen Embryo Transfer
Natural Cycle vs Programmed Cycle Frozen Embryo Transfer
The goal of this[ type of study: randomized controlled trial]is to compare Preeclampsia following Natural vs. Artificial Cycle in patients undergoing frozen embryo transfer.
- Conditions
- Infertility, Frozen Embryo Transfer, Preeclampsia and Eclampsia
- Trial name
- NCT05716139
- Testing
- Natural Cycle, Artificial Cycle
- Where
- India
- Volunteers
- 172 people
- Sponsor
- Indira IVF Hospital Pvt Ltd
Infertility
Predictors of Pregnancy Rate in Assisted Reproductive Technology According to Actual Guidelines
Goals: To explore the association of probability of pregnancy with certain prognostic factors in patients undergoing assisted reproductive technology in Russian population according to international and national guidelines.
- Trial name
- IRIS (NCT04249297)
- Testing
- Duphaston® (Dydrogesteron)
- Where
- 52 sites in Kazakhstan, Russia
- Volunteers
- 1,150 people
- Sponsor
- Abbott
Implantation Failure, Infertility
Endometrial Biopsy Prior to IVF in Those Patients With Prior Implantation Failure
This proposed research is a single center, prospective, single-blinded, randomized controlled trial, designed to evaluate IVF pregnancy outcomes following endometrial injury in 254 patients with implantation failure.
- Trial name
- EMBX/IVF (NCT01800513)
- Testing
- Endometrial Biopsy
- Where
- United States
- Volunteers
- 254 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Infertility, Recurrent Miscarriage
Effect of Influenza Vaccination on Donor Egg Recipient Outcomes
In this study the investigators propose a randomized controlled trial to evaluate the effect of influenza vaccination on clinical pregnancy rates among women undergoing in vitro fertilization as donor egg recipients.
- Trial name
- DE-FluVac (NCT02946177)
- Testing
- Influenza Vaccine, Sterile Saline
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Endometriosis, Infertility
Impact of Complete Surgery of Colorectal Deep Infiltrating Endometriosis on Fertility
The ENDOFERT Study is an open, multicenter, randomized, parallel-group, controlled trial. This study includes patients presenting colorectal DIE and infertility.
- Trial name
- ENDOFERT (NCT02948972)
- Testing
- complete surgery, In vitro fertilization without surgery
- Where
- 5 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Lille
Infertility
Synchronization of Ovarian Stimulation for in Vitro Fertilization With Follicular Wave Emergence
Ovarian stimulation is an important phase of in vitro fertilization (IVF) treatments. The harvest of a larger number of viable eggs per cycle compensate eventual laboratory difficulties and allow for the selection of embryos with…
- Trial name
- NCT01668056
- Testing
- Ovulation induction with choriogonadotropin alfa, Aspiration of the dominant follicle, Control
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Infertility, Poor Ovarian Reserve
Ovarian PRP Injections for Improved Embryo Quality Using Embryo Quality Score
Patients will have ovarian PRP treatments and embryo development will be observed using time-lapse imaging and AI software.
- Conditions
- Infertility, Poor Ovarian Reserve, Embryo Growth Disorder, in Vitro Fertilization
- Trial name
- NCT07020546
- Testing
- Ovarian Platelet-rich plasma (PRP) injections
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Generation Next Fertility
Primary Infertility Unspecified, Infertility
Routine Hysteroscopy in IVF/ICSI Cycles in Patients With Primary Unexplained Infertility
The aim of the present study is to evaluate the impact of hysteroscopy prior to starting the IVF (in vitro fertilisation) cycle on treatment outcome in women with unexplained primary infertility.
- Conditions
- Primary Infertility Unspecified, Infertility, Ovarian Hyperstimulation, Pregnancy
- Trial name
- NCT02416596
- Testing
- Hysteroscopy, Hysteroscope
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Infertility, Female, Pain, Postoperative
Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Control for Oocyte Retrieval
In this research study we want to learn more about how effective certain medications are at reducing pain after oocyte (egg) retrieval surgery and how effective they are at reducing the time between the retrieval and discharge…
- Trial name
- NCT03073980
- Testing
- IV Acetaminophen, PO Acetaminophen
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
In Vitro Fertilization, Infertility Assisted Reproductive Technology
Assessment of Reproductive Outcomes in Non-Male Factor Infertility Patients: Conventional in Vitro Fertilisation Versus Intracytoplasmic Sperm Injection
The aim of this clinical trial is to evaluate the efficiency of two fertilization techniques used in Assisted Reproduction: conventional In Vitro fertilization (cIVF) and Intracytoplasmic Sperm Injection (ICSI), in terms of…
- Trial name
- NCT06670586
- Testing
- conventional in vitro fertilization, intracytoplasmic sperm injection (ICSI)
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Maria Dolores Cuquerella Fernandez-Vazquez
Infertility
The Impact of the SPIKES Protocol With IVF Patients
The purpose of this study is to determine if the utilization of the SPIKES protocol for delivering bad news is perceived to be more compassionate and effective than the current standard of care for IVF patients receiving negative…
- Trial name
- NCT04917445
- Testing
- Spikes-focused bad news protocol
- Where
- 2 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Vitamin D Status
The Impact of Vitamin D Status on in Vitro Fertilization (IVF) Outcomes
Infertility is a common and psychologically devastating problem for 20% of Canadian couples. Approximately, 20% of infertile couples are diagnosed with unexplained infertility and left without an explanation for their inability…
- Trial name
- NCT01348594
- Where
- Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Endometrioma, Infertility
Ethanol Sclerotherapy Prior to ART
The goal of this randomized controlled trial is to assess the impact of ethanol sclerotherapy on ART cycle outcomes. The main questions it aims to answer are: 1.
- Conditions
- Endometrioma, Infertility, Sclerotherapy, ART
- Trial name
- START (NCT05962775)
- Testing
- Ethanol Sclerotherapy for Endometrioma
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ankara University
Infertility, Female
Prospective Assessment of Impact of Personalized Dosing of Low-dose Human Chorionic Gonadotropin (hCG) on in Vitro Fertilization (IVF) Outcomes
The purpose of the study is to determine the effect of tailoring dosage of low-dose hCG secondary to serum hCG levels during IVF ovarian stimulation on sustained implantation rates of preimplantation genetically tested euploid…
- Trial name
- NCT04852029
- Testing
- Low dose hCG
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
In Vitro Fertilisation Outcome
Triple-arm pH Comparison
The culturing human embryo in vitro is a process of myriad contributing elements. From these factors is the pH of embryo culture media, which is crucial for embryo development.
- Trial name
- Tri-pH (NCT02896777)
- Testing
- Transfer embryo from pH 7.20±0.02 on either Day 3 or day 5/6, Transfer embryo from pH 7.3±0.02 either Day 3 or day 5/6, Transfer embryo from pH of 7.4±0.02 on either Day 3 or day 5/6
- Where
- 6 sites in Egypt
- Volunteers
- 2,273 people
- Sponsor
- Ibn Sina Hospital
Fertility Disorders
Performance of CHLOE Algorithm on the Prediction of Blastocyst Formation
This is an observational, prospective, single-arm, multi-center, clinical study to evaluate the performance of CHLOE, an Artificial Intelligence (AI)-based software application, as adjunct information to support identifying…
- Trial name
- CHLOE (NCT05455281)
- Testing
- CHLOE
- Where
- 3 sites in United States, Israel
- Volunteers
- 55 people
- Sponsor
- Fairtility
Sub Fertility, Female, Fertility Disorders
Effects of Fasting on Success Rates of Assisted Reproductive Techologies
This exploratory study investigates fasting as a potential supportive therapy for infertility treatment in women undergoing in-vitro-fertilization (IVF) / intracystoplamsatic sperm injection (ICSI)
- Conditions
- Sub Fertility, Female, Fertility Disorders, Fertility Issues, Sub-fertility
- Trial name
- KiWuC (NCT04998591)
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Charite University, Berlin, Germany
IVF, In Vitro Fertilization
The Effect of a Four-Week Hatha Yoga Intervention to Improve Quality of Life, Anxiety, and Depressive Symptoms in Individuals Undergoing Assisted Reproductive Technology (ART) Treatment
The goal of this clinical trial is to learn if a four-week yoga program works to improve quality of life in people undergoing IVF (In Vitro Fertilization).
- Conditions
- IVF, In Vitro Fertilization, Quality of Life (QOL), Anxiety
- Trial name
- NCT07415850
- Testing
- Yoga
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Villanova University