Clinical trials: In-hospital Cardiac Arrest
Cardiac Arrest
Prospective Study of 3 Phone Assistance Strategies to Achieve a Continuous Cardiac Massage
This study must evaluate the benefit of a continuous audio guidance on the effectiveness of MCE directed by a volunteer. The evaluation of the MCE for this study is based on both quantitative criteria (based on the…
- Trial name
- TeleMacc (NCT01936597)
- Testing
- Therapeutic and preventive strategies
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Sudden Cardiac Arrest, Out-of-hospital Cardiac Arrest (OHCA)
FEMART-1 Pilot Study
The FEMART-1 Pilot Study is focused on evaluating the feasibility, safety, and procedural timing of prehospital femoral arterial sheath placement in patients with non-traumatic out-of-hospital cardiac arrest (OHCA), both during…
- Conditions
- Sudden Cardiac Arrest, Out-of-hospital Cardiac Arrest (OHCA), Cardiogenic Shock Acute
- Trial name
- FEMART-1 (NCT07596446)
- Testing
- Prehospital Ultrasound-Guided Femoral Arterial Sheath Placement
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Emergency Medical Service, Prague
Trauma, Cardiac Arrest
Airway Management Study in Physician Manned Helicopter Emergency Medical Services
An international airway management expert group has recently developed an Utstein-style template for uniform reporting of data from prehospital advanced airway management.
- Conditions
- Trauma, Cardiac Arrest, Emergencies
- Trial name
- AIRPORT (NCT01502111)
- Where
- Norway
- Volunteers
- 2,333 people
- Sponsor
- Norwegian Air Ambulance Foundation
Cardiac Arrest, Out-Of-Hospital, Hypothermia, Induced
Pediatric Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients (P-ICECAP)
This is a multicenter trial to establish the efficacy of cooling and the optimal duration of induced hypothermia for neuroprotection in pediatric comatose survivors of cardiac arrest.
- Conditions
- Cardiac Arrest, Out-Of-Hospital, Hypothermia, Induced, Hypoxia-Ischemia, Brain
- Trial name
- NCT05376267
- Testing
- Therapeutic Hypothermia
- Where
- 65 sites in United States, Australia and 3 more
- Volunteers
- 900 people
- Sponsor
- University of Michigan
Out-of-Hospital Cardiac Arrest
Arizona Prehospital CPR Quality Improvement Project
The quality of cardiopulmonary resuscitation (CPR) provided to patients with out-of-hospital cardiac arrest (OHCA) is often suboptimal.
- Trial name
- NCT01258244
- Testing
- Audiovisual Feedback
- Where
- 2 sites in United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Valleywise Health
Cardiac Arrest, Out-Of-Hospital
Gathering Evidence on Best Practices for Lay Rescuer CPR Training
The goal of this prospective trial is to compare CPR skill and attitudes in lay rescuers. The main question[s] it aims to answer are: What is the optimal training timing, duration, and frequency for lay rescuers that leads to CPR…
- Trial name
- NCT05908500
- Testing
- CPR Training, CPR Manikin Type
- Where
- United States
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno
Out-of-Hospital Cardiac Arrest (Simulated)
Simulation and Feasibility Study of Drone-Delivered AED for Out-of-Hospital Cardiac Arrest
Background: Survival after out-of-hospital cardiac arrest (OHCA) depends heavily on early defibrillation. Reducing the time from cardiac arrest to defibrillation is a key factor in improving survival.
- Trial name
- NCT07508774
- Testing
- Drone-Based AED Delivery System, Standard Ground Ambulance Response Pathway Simulation
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ye Sheng
Out-of-hospital Cardiac Arrest (OHCA)
Ketamine Sedation As Neuroprotective Agent Following Out-of-hospital Cardiac Arrest
OHCA is a critical medical emergency with significant mortality and morbidity primarily due to hypoxic-ischemic brain injury (HIBI).
- Trial name
- KETOHCA (NCT06744361)
- Testing
- esketamine hydrochloride, propofol
- Where
- 2 sites in Denmark
- Volunteers
- 282 people
- Sponsor
- Christian Hassager
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest
Emergency Resuscitative Endovascular Balloon Occlusion of the Aorta in Out of Hospital Cardiac Arrest
This study will assess the feasibility of performing pre-hospital resuscitative endovascular balloon occlusion of the aorta (REBOA) as an adjunct to conventional Advanced Life Support (ALS) in patients suffering from…
- Conditions
- Out-Of-Hospital Cardiac Arrest, Cardiac Arrest, Cardiac Arrhythmia, Ventricular Fibrillation
- Trial name
- ERICA-ARREST (NCT06071910)
- Testing
- ER-REBOA catheter
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Queen Mary University of London
Pediatric, Cardiac Arrest
Pediatric Out-of-hospital Cardiopulmonary Arrest
The objective of this observational and retrospective study is to determine the predictive factors of in-hospital mortality following an out-of-hospital cardiopulmonary arrest (CPA) in the population under 18 years old.
- Conditions
- Pediatric, Cardiac Arrest, Out-Of-Hospital Cardiac Arrest
- Trial name
- Ped-CPA (NCT05474131)
- Where
- France
- Volunteers
- 137 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Sudden Cardiac Arrest, Seizures
EEG in Resuscitated In-hospital Patients
In Kuopio University Hospital Department of Clinical Neurophysiology there have been designed a fast EEG electrode, that is suitable for acute emergency use.
- Trial name
- NCT02349087
- Testing
- Acute EEG with fast applicable EEG electrode
- Where
- Finland
- Volunteers
- 1 people
- Sponsor
- Kuopio University Hospital
Cardiac Arrest
Evaluation of the Heart's Respiratory Quotient as Predictive Value After Extra-hospital Cardiac Arrest
It has been shown that elevation of the heart's respiratory quotient after cardiac surgery is predictive of the complications occurrence.
- Trial name
- QUANTIC (NCT04211207)
- Testing
- non invasive monitoring value
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Grenoble
Heart Arrest, Arrhythmias, Cardiac
Cardiac Arrest Post-Discharge ECG Monitoring
The primary aim is to conduct a prospective observational cohort study to analyze the incidence of serious arrhythmic events that occur within 14 days after hospital discharge in patients who had been hospitalized for cardiac…
- Conditions
- Heart Arrest, Arrhythmias, Cardiac, Electrocardiography
- Trial name
- CArPEM (NCT05337371)
- Testing
- ECG patch (Philips ePatch® 2.0)
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Extracorporeal Membrane Oxygenation, Cardiac Arrest
ON-SCENE Initiation of Extracorporeal CardioPulmonary Resuscitation During Refractory Out-of-Hospital Cardiac Arrest
Hypothesis: Implantation of on-scene ECPR by the HEMS teams in patients with sustained out-of-hospital cardiac arrest, results in the rapid return of circulation and, thus, improved survival and less neurological impairment…
- Trial name
- ON-SCENE (NCT04620070)
- Testing
- ECPR
- Where
- 4 sites in Netherlands
- Volunteers
- 221 people
- Sponsor
- Erasmus Medical Center
Out of Hospital Cardiac Arrest
Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation
The hypothesis of this study is Dispatcher-Activated Neighborhood Access Defibrillation and Cardiopulmonary Resuscitation (NAD-CPR) would improve survival of out-of-hospital cardiac arrest (OHCA).
- Trial name
- NCT02010151
- Testing
- NAD-CPR
- Where
- South Korea
- Volunteers
- 3,194 people
- Sponsor
- Seoul National University Hospital
Heart Arrest
Thrombolysis Using Tenecteplase (Metalyse®) in Cardiac Arrest - The TROICA Trial
The general aim of this study is to compare the efficacy and safety of tenecteplase to standard treatment during cardiopulmonary resuscitation in patients suffering from out-of-hospital cardiac arrest.
- Trial name
- NCT00157261
- Testing
- tenecteplase
- Where
- 68 sites in Austria, Belgium and 7 more
- Volunteers
- 1,050 people
- Sponsor
- Boehringer Ingelheim
Cardiac Arrest, Out-Of-Hospital, Ventricular Fibrillation
Utility and Procedural Feasibility of REBOA Operationalized for Non-Trauma Application (UP-FRONT)
Single center randomized-controlled trial in out-of-hospital cardiac arrest (OHCA) patients. This study will investigate the feasibility and utility of the Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)…
- Conditions
- Cardiac Arrest, Out-Of-Hospital, Ventricular Fibrillation, Ventricular Tachycardia
- Trial name
- UP-FRONT (NCT05236920)
- Testing
- Resuscitative Endovascular balloon occlusion of the aorta using a REBOA catheter device
- Sponsor
- University of Alabama at Birmingham
Out-of-Hospital Cardiac Arrest, Ventricular Fibrillation
DIagnostics, Fatty Acids and Vitamin D in SCA
Sudden cardiac death (SCD) is a major cause of mortality in industrialized countries and represents a major health issue. The survival rate after out-of-hospital cardiac arrest (OHCA) is only 10-15%, regardless of first recorded…
- Trial name
- DIFAD-SCA (NCT02886273)
- Testing
- Group 1, Group 2, Group 3
- Where
- Norway
- Volunteers
- 116 people
- Sponsor
- Helse Stavanger HF
Out-of-hospital Cardiac Arrest (OHCA)
Emergency Total ECLS vs Standard ACLS With ECMO Bailout for Survival in Refractory OHCA
The goal of the clinical trial is to learn if early extracorporeal life support ( ECLS ) will save more out-of-hospital cardiac arrest ( OHCA ) patients with good neurological outcome.
- Trial name
- ECLS-OHCA (NCT06692075)
- Testing
- extracorporeal life support, standard ACLS
- Where
- Taiwan
- Volunteers
- 332 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Cardiac Arrest
Develop, Implement and Assess Effectiveness of Early Warning Score (EWS) for Moneragala District General Hospital
Rationale: Early detection and timely interventions are important determinants of clinical outcome in people with acute illness.
- Trial name
- EWS (NCT02523456)
- Testing
- Training, Introduce EWS
- Where
- Sri Lanka
- Volunteers
- 18,000 people
- Sponsor
- Ministry of Health, Sri Lanka