Clinical trials: In-hospital Mortality
Community-Acquired Infections, Pneumonia
Community-acquired Pneumonia in Buskerud County in Norway
The purpose of this study is to determine the etiology of community-acquired pneumonia, to assess risk factors and to investigate potential prognostic biomarkers of serious disease and fatal outcome.
- Trial name
- NCT01563315
- Where
- Norway
- Volunteers
- 270 people
- Sponsor
- Vestre Viken Hospital Trust
Surgery, Postoperative Complications
Colombian Surgical Outcomes Study - COLSOS
An observational, analytical, multicentre prospective cohort study will be conducted throughout Colombia. A sample size of 1353 patients is needed to achieve significance in our primary objective; however, convenience sampling is…
- Conditions
- Surgery, Postoperative Complications, Hospital Mortality
- Trial name
- COLSOS (NCT05147623)
- Testing
- Any surgery/procedure
- Where
- 2 sites in Colombia
- Volunteers
- 1,353 people
- Sponsor
- Fundación Cardioinfantil Instituto de Cardiología
Out-Of-Hospital Cardiac Arrest
Targeted Therapeutic Mild Hypercapnia After Resuscitated Cardiac Arrest
The TAME Cardiac Arrest trial will study the ability of higher arterial carbon dioxide (PaCO2) levels to reduce brain damage, comparing giving patients 'normal' to 'slightly higher than normal' blood PaCO2 levels and assessing…
- Trial name
- TAME (NCT03114033)
- Testing
- Targeted therapeutic mild hypercapnia, Targeted normocapnia (Standard care)
- Where
- 52 sites in Australia, Belgium and 12 more
- Volunteers
- 1,700 people
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Hyponatremia, Hospitalisation
Mortality and Neurologic Outcomes in Rapid vs. Slow Hyponatremia Correction
This study examines the impact of different rates of sodium correction on the outcomes of patients with severe hyponatremia (serum sodium ≤ 120 mEq/L).
- Conditions
- Hyponatremia, Hospitalisation, Mortality, SEVERE HYPONATREMIA
- Trial name
- RASC-HypoNa (NCT06675591)
- Testing
- Rapid sodium correction, Slow sodium correction
- Where
- Argentina
- Volunteers
- 2,037 people
- Sponsor
- Hospital Italiano de Buenos Aires
Acute Myocardial Infarction
Investigating Variation in Hospital Acute Coronary Syndrome Outcomes
To investigate the causes of hospital variation in outcomes from acute coronary syndromes in England and develop recommendations for improving patient care.
- Trial name
- NCT01819103
- Volunteers
- 5,555 people
- Sponsor
- University of Leeds
ICU Mortality
Comparison of Simplified Acute Physiology Score (SAPS II) , Sequential Organ Failure Assessment (SOFA) and Acute Physiology and Chronic Health Evaluation) APACHE II Scoring Systems for Predicting Mortality of Critically Ill Patients Admitted in a Tertiary Hospital Intensive Care Unit.
This is a descriptive analytical prospective study to compare the performance of SOFA score, SAPSII score and APACHE II score in ICU mortality prediction.
- Trial name
- SAPS II SOFA (NCT07780617)
- Where
- Nepal
- Volunteers
- 201 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Sepsis, Neonatal Mortality
Clean Trial - Chlorination to Reduce Enteric and Antibiotic Resistant Infections in Neonates
The CLEAN (ChLorine to reduce Enteric and Antibiotic resistant infections in Neonates) cluster randomized controlled trial in western Kenya will evaluate the impact of a multi-component chlorination intervention in health care…
- Conditions
- Sepsis, Neonatal Mortality, Antibiotic Resistant Infection, Enteric Infections
- Trial name
- CLEAN (NCT06824350)
- Testing
- chlorination for water disinfection and surface disinfection, infection prevention and control messaging
- Where
- 2 sites in United States, Kenya
- Volunteers
- 45,450 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Heart Failure
Patient Journey in Hospital With Acute Heart Failure
A multicentre, prospective, observational, hospital-based registry of patients with acute heart failure (AHF) those whose care was guided by a cardiologist in Turkey.
- Trial name
- JourneyHF-TR (NCT02621203)
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Mehdi Zoghi
Multidrug-Resistant Organism Infection, Healthcare-Associated Infections (HAIs)
Prevalence of Multidrug-Resistant Organism Infections in General Adult Wards in Argentina (PREV-AR 2 - IGA)
This study measures how common infections caused by multidrug-resistant organisms (MDROs) are among adult patients hospitalized in general medical and surgical wards in Argentina, and how these infections relate to in-hospital…
- Conditions
- Multidrug-Resistant Organism Infection, Healthcare-Associated Infections (HAIs), Antimicrobial Resistance (AMR)
- Trial name
- PREVAR 2-IGA (NCT07797569)
- Testing
- Observational data collection (chart review / point-prevalence survey)
- Where
- Argentina
- Volunteers
- 2,000 people
- Sponsor
- Hospital Italiano de Buenos Aires
In-hospital Mortality, Non-COVID Deaths
Pre- vs Post-Pandemic Risk-adjusted Survival Rates in the US Hospitals
This study aims to perform a retrospective cohort study of administrative health data to understand how care delivery performance varies across US hospitals post-COVID-19 pandemic compared to the pre-pandemic performance.
- Conditions
- In-hospital Mortality, Non-COVID Deaths, Surge
- Trial name
- NCT06651645
- Testing
- COVID-19 Surge
- Where
- United States
- Volunteers
- 30,000,000 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Geriatric Patients, Emergencies
European Geriatric Emergency Departments Registry Study
Geriatric presentations to emergency services comprise a significant percentage of all emergency service presentations in Europe and it has been reported that 3-23% of all emergency service presentations from various regions of…
- Conditions
- Geriatric Patients, Emergencies, Length of Stay, Early Warning Score
- Trial name
- EGERS (NCT04680299)
- Where
- 7 sites in Croatia, France and 4 more
- Volunteers
- 3,000 people
- Sponsor
- Gazi University
Gastric Cancer
Annual Hospital Volume and and Short-term Postoperative Outcomes After Gastric Cancer Resection
The effect of centralisation measures on the operative outcomes after gastric cancer resection in Switzerland has not been highlighted yet.
- Trial name
- NCT07072429
- Testing
- Gastric cancer resection
- Where
- Switzerland
- Volunteers
- 3,112 people
- Sponsor
- Cantonal Hospital of St. Gallen
Appointments and Schedules, Outpatient Clinics, Hospital/Economics
Non Attendance at Scheduled Appointments as a Marker of Mortality and Hospital Admission
To evaluate the association of non attendance at scheduled appointments with visits in the emergency department, hospitalizations and mortality during one year follow up.
- Conditions
- Appointments and Schedules, Outpatient Clinics, Hospital/Economics, Emergency Department, Hospitalization
- Trial name
- NCT02210637
- Where
- Argentina
- Volunteers
- 177,083 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
Malnutrition
Comparison of CIPA With the GLIM Criteria and Prevalence of Sarcopenia in Inpatients
Determine the diagnostic quality of the CIPA tool, in inpatients with stays longer than three days, in the observation of risk of malnutrition compared to the gold standard GLIM as a diagnosis of malnutrition.
- Trial name
- NCT06031766
- Testing
- Dietary supplement
- Where
- Spain
- Volunteers
- 490 people
- Sponsor
- University Hospital of the Nuestra Señora de Candelaria
Maternal Mortality
Outcomes of Uterine Rupture
Uterine rupture (UR) is a serious, life-threatening obstetric complication. UR is associated with an increased risk of maternal and perinatal morbidity and mortality, particularly in developing countries compared to developed…
- Trial name
- NCT02878226
- Testing
- repair of rupture
- Where
- Egypt
- Volunteers
- 65 people
- Sponsor
- Assiut University
Life Quality, Hospital Mortality
Effect of Nutritional Support and Early Rehabilitation on Sepsis
Sepsis is a syndrome of life-threatening organ dysfunction caused by a dysregulated host response to infection.Acute catabolic response in critically ill patients struck by sepsis, manifested by massive protein breakdown in a…
- Trial name
- NUSPOTER (NCT05781971)
- Testing
- high protein, rehabilitation, standard protein
- Volunteers
- 1,600 people
- Sponsor
- Jinling Hospital, China
COVID-19 Infection in Hemodialysis Patients
COVID-19 Infection in Hemodialysis Patients
Dialysis patients have a higher risk of infectious complications including complications from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes COVID-19.
- Trial name
- NCT05069532
- Testing
- MSCT chest, PCR
- Volunteers
- 100 people
- Sponsor
- Assiut University
Aortic Dissection
Factors Influencing Perioperative Mortality in Type A Acute Aortic Dissections Operated at Dijon University Hospital
Type A acute aortic dissections are a rare condition whose natural evolution is catastrophic. Global mortality remains high even if it decreased last years.
- Trial name
- NCT04408404
- Testing
- Acute aortic dissection
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Centre Hospitalier La Chartreuse
Stroke, Acute, Pulmonary Rehabilitation
Effect of Pulmonary Rehabilitation Program on Patients With Acute Ischemic Stroke, Mortality and Disability
Severe stroke remains an important cause of mortality and morbidity, despite advances in disease management, acute treatment and secondary measures.
- Conditions
- Stroke, Acute, Pulmonary Rehabilitation, Morality
- Trial name
- NCT04110652
- Testing
- pulmonary rehabilitation program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Myocardial Infarction
Comparison of Information Recorded in MINAP, GPRD and HES: a CALIBER Study
Medical information is increasingly processed electronically. This study will describe the similarities and differences in the data recorded by different databases of electronic healthcare database.
- Trial name
- NCT01569139
- Where
- 3 sites in United Kingdom
- Volunteers
- 21,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine