Clinical trials: Incidence
Pressure Ulcers
P400 for Stage II-IV Pressure Ulcers in Home and Extended Care
To assess the efficacy of a pressure ulcer treatment mattress, the P400 mattress, in the treatment of multiple Stage II or one or more large Stage III or IV pressure ulcers in the home care and extended care (nursing home)…
- Trial name
- P400 (NCT01139879)
- Testing
- P400 mattress
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hill-Rom
HIV Infection, Human Immunodeficiency Virus 1 Positive
Incidence and Prevalence of Cancer in People Living With HIV/AIDS at Cancer Centers in Latin America
This trial studies the frequency of incident and prevalent of cancer in people living with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) at cancer centers in Latin America.
- Conditions
- HIV Infection, Human Immunodeficiency Virus 1 Positive, Malignant Neoplasm, Recurrent Malignant Neoplasm
- Trial name
- NCT04089488
- Testing
- Medical Chart Review, Survey Administration
- Where
- 4 sites in Argentina, Brazil and 1 more
- Volunteers
- 175 people
- Sponsor
- AIDS Malignancy Consortium
Hypogonadism, Cardiovascular Diseases
A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men
This is a double-blinded and placebo-controlled study of topical testosterone replacement therapy (TRT) in symptomatic hypogonadal men with pre-existing cardiovascular disease (CVD) or increased risk for CVD.
- Trial name
- TRAVERSE (NCT03518034)
- Testing
- AndroGel®
- Where
- 384 sites in United States, Puerto Rico
- Volunteers
- 5,246 people
- Sponsor
- AbbVie
Sore Throat, Pain
Post Operative Sore Throat and Dexamethasone
Sore throat is a common postoperative complaint that can lead to morbidity and patient dissatisfaction . The incidence of sore throat has been reported to be between 6% and 90% even under optimal intubating conditions.
- Trial name
- NCT01052038
- Testing
- Dexamethasone 0.05mg/kr administration, Dexamethasone 0.1mg/kg
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Northwestern University
Colorectal Cancer
A Study of Amifostine (Ethyol) in Patients With Colorectal Cancer
The purpose of this study is to determine the effect of amifostine (ETHYOL) on decreasing the rate and severity of nerve dysfunction or neuropathy (numbness and tingling in hands and feet) associated with FOLFOX chemotherapy.
- Trial name
- NCT00601198
- Testing
- Amifostine
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Cincinnati
Leg Injuries
Effects of Foot Strengthening on the Incidence of Injuries in Long Distance Runners
The main objective of this trial is to investigate the effects of a training protocol for the foot and ankle complex on the prevalence of running related injuries on long distance runners.
- Trial name
- NCT02306148
- Testing
- Foot and ankle strengthening
- Where
- Brazil
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Herpes Zoster, Herpes Zoster Vaccine
Study to Estimate the Burden of Herpes Zoster (HZ) and Post-herpetic Neuralgia (PHN) in Italy
The purpose of this study is to collect data on the incidence, complications, economic burden and impact on the quality of life in adults aged ≥ 50 years with HZ disease in Italy.
- Trial name
- NCT01772160
- Testing
- Data collection
- Where
- 43 sites in Italy
- Volunteers
- 395 people
- Sponsor
- GlaxoSmithKline
HIV Infections
Botswana TDF/FTC Oral HIV Prophylaxis Trial
This study tested whether taking a pill of tenofovir and emtricitabine (two antiretroviral medicines) was safe for sexually-active young adults in Botswana without HIV infection and whether it reduced their risk of getting an HIV…
- Trial name
- TDF2 (NCT00448669)
- Testing
- Tenofovir Disoproxil Fumarate 300 mg + Emtricitabine 200 mg
- Where
- 2 sites in United States, Botswana
- Volunteers
- 1,219 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Diabetes Mellitus, Type 2
Post-authorization Safety Study in Type 2 Diabetic Patients in Saudi Arabia Treated With Empagliflozin to Assess the Incidence of Ketoacidosis, Severe Complications of Urinary Tract Infection, Volume Depletion, and Dehydration
The objectives of this study are to assess the risk of ketoacidosis, severe urinary tract infections, volume depletion, and dehydration associated in patients with T2DM initiating Empagliflozin compared to patient initiating a…
- Trial name
- NCT03764631
- Testing
- Empagliflozin, Dipeptidyl-peptidase 4 (DPP-4) inhibitors
- Where
- 21 sites in Saudi Arabia
- Volunteers
- 1,502 people
- Sponsor
- Boehringer Ingelheim
Atrial Fibrillation
REVEAL AF: Incidence of AF in High Risk Patients
This study is to determine, through continuous monitoring with the Reveal implantable cardiac monitor (ICM), the incidence of atrial fibrillation (AF) in patients suspected to be at high risk for having AF and to understand how…
- Trial name
- NCT01727297
- Testing
- REVEAL Implantable Cardiac Monitor
- Where
- 58 sites in United States, Austria and 5 more
- Volunteers
- 446 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
HIV Infections
Open Label Extension (OLE) of the TDF2 Study, Botswana
This study is an open label and is an extension to the TDF2 study in which the investigators offered daily oral tenofovir/emtricitabine (TDF/FTC) for a maximum of 12 months to HIV uninfected former participants of the TDF2 study.
- Trial name
- TDF2-OLE (NCT04318210)
- Testing
- Tenofovir Disoproxil Fumarate 300 mg + Emtricitabine 200 mg
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Aortic-valve Replacement
Behavior of Valve Leaflets Following Aortic Valve Implant
This is a prospective, interventional, multi-center trial to report the overall incidence of reduced leaflet motion identified by CT imaging in patients receiving a commercially approved LivaNova bioprosthetic aortic heart valve…
- Trial name
- BELIEVE (NCT03200574)
- Testing
- 4D Cardiac CT Scan, LivaNova Bioprothetic Aortic Valve Implant
- Where
- 11 sites in United States, Canada
- Volunteers
- 88 people
- Sponsor
- Corcym S.r.l
Gastric Ulcer
Evaluating PN 400 (VIMOVO) in Reducing Gastric Ulcers Compared to Non-steroidal Antiinflammatory Drug (NSAID) Naproxen
This study uses a randomized, double-blind, controlled design to demonstrate that PN400 (esomeprazole and naproxen) is more effective in reducing the occurrence of gastroduodenal ulcers, dyspepsia, and heartburn in subjects at…
- Trial name
- NCT00527787
- Testing
- PN400 (VIMOVO), Naproxen
- Where
- United States
- Volunteers
- 434 people
- Sponsor
- POZEN
Delirium
Efficacy and Safety of Suvorexant (MK-4305) for Reducing Incidence of Delirium in Japanese Participants at High Risk of Delirium (MK-4305-085)
The goal of this study is to evaluate the efficacy and safety of suvorexant (MK-4305) for reducing the incidence of delirium in Japanese participants who are at high risk of delirium.
- Trial name
- NCT04571944
- Testing
- Suvorexant
- Where
- 50 sites in Japan
- Volunteers
- 207 people
- Sponsor
- Merck Sharp & Dohme LLC
Residual Neuromuscular Blockade in Elderly Patients
The Effect of Age on the Incidence of Postoperative Residual Neuromuscular Blockade
Residual neuromuscular blockade is frequently observed in the early postoperative period when patients have received a general anesthetic with muscle relaxants.
- Trial name
- NCT01545193
- Testing
- Age and incidence of residual neuromuscular blockade
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Endeavor Health
Stem Cell Transplant Complications
A Double-blind Randomized Placebo Controlled Clinical Trial Evaluating Effect of Chlorhexidine Gluconate 2% Cloth vs Placebo Cloth Baths on the Incidence of Central Line-Associated Blood Stream Infections in Outpatient Hematopoietic Stem Cell Transplant Patients
This study evaluates the use of 2% CHG washcloths in an outpatient setting for adults after hematopoietic stem cell transplant in prevention of central line associated blood stream infections.
- Trial name
- NCT03030989
- Testing
- Chlorhexidine Gluconate 2% Wipe
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Chicago
Post-operative Pneumonia, Lung Cancer
Prevention of Post-operative Pneumonia (POPP)
Postoperative pneumonia is a major complication in patients undergoing thoracic surgery. It leads to considerable morbidity and contributes to perioperative morbidity.
- Conditions
- Post-operative Pneumonia, Lung Cancer, Esophageal Cancer
- Trial name
- POPP (NCT01446874)
- Testing
- 0.12% chlorhexidine solution
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Washington University School of Medicine
Diabetes Mellitus, Type 2, Cancer
Cohort Study of Pioglitazone and Cancer Incidence in Participants With Diabetes Mellitus.
The purpose of this study was to evaluate whether treatment with pioglitazone is associated with risk of incident cancer at the 10 most common sites in a cohort of participants with recognized diabetes.
- Trial name
- NCT02958956
- Testing
- Pioglitazone
- Volunteers
- 236,507 people
- Sponsor
- Takeda
Multiple Sclerosis
Tecfidera Slow-Titration Study
The primary objective of the study is to assess whether a 6-week titration (compared with a 1-week titration) is effective in reducing the incidence of dimethyl fumarate (DMF [Tecfidera])-related gastrointestinal (GI) adverse…
- Trial name
- TITRATION (NCT02428231)
- Testing
- dimethyl fumarate
- Where
- 20 sites in United States, Belgium and 2 more
- Volunteers
- 62 people
- Sponsor
- Biogen
Gastroduodenal Ulcerations, Erosion
Clinical Trial Evaluating Gastrointestinal Damage Following Administration PL3100 or Naproxen in At-Risk Adults
The purpose of this study is to determine the subchronic gastrointestinal (GI) safety of PL3100 versus Naproxen in normal healthy volunteers.
- Trial name
- NCT01139190
- Testing
- PL3100, Naproxen
- Where
- 2 sites in United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- PLx Pharma