Clinical trials: Incision, Surgical
Infection, Surgical Site
IO vs IV Vancomycin in Tourniquetless TKA
Purpose of this study is to compare the efficacy of intravenous and intraosseous antibiotic administration techniques during tourniquetless total knee arthroplasty.
- Trial name
- NCT05705843
- Testing
- Intraosseous Vancomycin Injection, Intravenous Vancomycin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The Methodist Hospital Research Institute
Hernia Incisional, Exercise
Impact of Core Muscle Training on Incisional Hernia and Pain After Abdominal Surgery
The current practice to avoid incisional hernia, one of the most frequent complications following abdominal surgery, is to minimize core muscle activity in the postoperative phase.
- Trial name
- NCT03808584
- Testing
- Physiotherapy
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 588 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Surgical Site Infection, Unplanned Fracture-Related Reoperation
Pre-operative Aqueous Antiseptic Skin Solutions in Open Fractures
The prevention of infection is the single most important goal influencing peri-operative care of patients with open fractures. Standard practice in the management of open fractures includes sterile technique and pre-operative…
- Conditions
- Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture
- Trial name
- Aqueous-PREP (NCT03385304)
- Testing
- 10% povidone-iodine (1% free iodine) in purified water, 4% chlorhexidine gluconate (CHG) in purified water
- Where
- 15 sites in United States, Canada and 1 more
- Volunteers
- 1,638 people
- Sponsor
- University of Maryland, Baltimore
Laparoscopic Colectomy
Incisional Hernia After Midline Versus Transverse Extraction Incision in Laparoscopic Colectomy
Incisional hernia (IH) is a common complication of midline laparotomy. Despite the hope that laparoscopic colon resection would result in fewer incisional hernias, prospective studies demonstrate a similar incidence to open…
- Trial name
- NCT01247389
- Testing
- laparoscopic colectomy
- Where
- Canada
- Volunteers
- 165 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Wound Heal
Platysma Incision Cosmesis
The anterior cervical fusion and decompression (ACDF) surgery provides direct access to symptomatic areas of the cervical spine.
- Trial name
- NCT03338608
- Testing
- Anterior Cervical Decompression and Fusion, Vertical Platysma Incision, Transverse Platysma Incision
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Boston Medical Center
Impacted Tooth, Postoperative Complications in Maxillofacial Surgery
Effectiveness of Postoperative Topical and Oral Antibiotics on Impacted Mandibular 3rd Molar Surgery.
This randomized controlled trial evaluates the effectiveness of postoperative topical antibiotics compared with oral antibiotics in patients undergoing surgical extraction of impacted mandibular third molars.
- Conditions
- Impacted Tooth, Postoperative Complications in Maxillofacial Surgery, Surgical Wound Infection, Facial Pain
- Trial name
- POTA-M3S (NCT07573033)
- Testing
- Topical Antibiotic, Oral antibiotic therapy
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Liaquat College of Medicine and Dentistry
Wound Complication
Cesarean Skin Incision Trial
The purpose of this study is to determine if there is a difference between Pfannenstiel and midline vertical skin incision at time of cesarean section in preventing wound complications in the morbidly obese patient.
- Trial name
- C-SIT (NCT01897376)
- Testing
- Pfannenstiel incision, vertical skin incision
- Where
- 2 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pocket Hematoma
Efficacy of the hYpothermic Compression Bandage in the Surgical Wound of Cardiac Devices
The aim of this study is to evaluate the efficacy of hypothermic compression bandaging versus conventional compression bandaging, for the prevention of surgical wound hematoma of cardiac implementable electronic devices in…
- Trial name
- EYRA (NCT05500768)
- Testing
- hypothermic compression bandage, Conventional compression bandage
- Where
- Spain
- Volunteers
- 310 people
- Sponsor
- Hospital Clinic of Barcelona
Obesity, Diabetes
Effects of Prevena Therapy on Obese and or Diabetic Patients With Surgical Groin Sites
The purpose of the study is to determine the effects of Prevena therapy on decreasing groin surgical site infections in patients who are obese and /or diabetic having vascular surgery.
- Conditions
- Obesity, Diabetes, Peripheral Vascular Disease
- Trial name
- NCT01983215
- Testing
- Prevena vac
- Where
- United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Dr. Jean E. Starr, MD
Post-operative Pain, Acute
To Compare the Skin Incision Made by the Electrocautery and Scalpel in Inguinal Hernia Repair
The Groin hernia repair is a commonly performed general surgery procedure in both adults and children with inguinal hernias constituting more than 95% of all groin hernia repairs.
- Trial name
- NCT05666973
- Testing
- Open Mesh Hernioplasty
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Incisional Surgical Site Infections
Total Occlusive Ionic Silver-containing Dressing vs Mupirocin Ointment Application vs Conventional Dressing in Elective Colorectal Surgery: Effect on Incisional Surgical Site Infection
The patients were randomized into 3 groups: those patients undergoing a ionic silver-containing dressing (ISD) (Group 1), those undergoing a Mupirocin ointment application (MOA) (Group 2) and those using a conventional dressing…
- Trial name
- NCT02267122
- Testing
- ionic silver-containing dressing, Mupirocin ointment application
- Volunteers
- 147 people
- Sponsor
- Hospital General Universitario Elche
Appendicitis (Diagnosis)
Precision Antibiotic Dosing for Appendectomy
This research is studying a drug called cefoxitin already approved by the Food and Drug Administration (FDA) to reduce the risk of infection after surgery to remove an appendix.
- Trial name
- PANDA (NCT06860802)
- Testing
- Cefoxitin
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Michigan
Full-thickness Skin Defects, Degloving Injuries
RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction
A prospective randomized within-subject controlled study to compare the clinical performance of conventional autografting with and without the RECELL system on acute non-burn full-thickness skin defects.
- Conditions
- Full-thickness Skin Defects, Degloving Injuries, Crush Injuries, Laceration of Skin
- Trial name
- NCT04091672
- Testing
- Control Intervention (Conventional Autograft), Investigational Intervention (RECELL + more widely meshed autograft)
- Where
- 18 sites in United States
- Volunteers
- 65 people
- Sponsor
- Avita Medical
Zygomatic Fractures
A Method of Calculating the Shortest Incision for Internal Fixation of Zygomatic Arch Fracture
In this study, a new method was proposed to calculate the length of sideburns mini incision for zygomatic arch fracture. The purpose of this study was to compare the sideburns mini incision calculated by this method with the…
- Trial name
- NCT05381337
- Testing
- sideburns mini incision, coronal scalp incision
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Wei Jing
Incarcerated Hernia, Appendicitis Acute
Prevention of Postoperative Hernias in Emergency Surgery
The aim of this observational study is to understand the risk factors and incidence of postoperative hernias among patients undergoing emergency surgery.
- Conditions
- Incarcerated Hernia, Appendicitis Acute, Cholecystitis, Acute, Ileus
- Trial name
- PROPHECY (NCT06815822)
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Jan Kochanowski University
Hysteroscopy, Oocyte Recipients
Hysteroscopy With Fundus Uterus Scratching Incision VS Office Hysteroscopy Before ET With Donor Eggs
A prospective randomised control trial of the impact of the fundus edometrial incision during hysteroscopy in oocyte recipients.
- Trial name
- NCT04580056
- Testing
- Uterine fundus endometrial incision during hysteroscopy
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assisting Nature
Next Generation Sequencing (NGS), Surgical Site Infection (SSI)
Efficacy of Integrating Next Generation Sequencing for Treatment of Surgical Site Infection After Fracture Fixation:
The study focuses on the serious problem of infections and wound-healing issues that can happen after high-energy bone fractures.
- Conditions
- Next Generation Sequencing (NGS), Surgical Site Infection (SSI), Fracture Fixation
- Trial name
- NGS (NCT07458230)
- Testing
- NGS diagnostic findings
- Where
- 18 sites in United States
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Malocclusion
Comparing of the Clinical Outcome of Periodontal Accelerated Osteogenic Orthodontics With Horizontal or Vertical Releasing Incisions
The study aims to compare the effect of periodontal accelerated osteogenic orthodontics (PAOO) with horizontal or vertical releasing incisions on operation time, healing, adverse effects, and effectiveness of bone augmentation.
- Trial name
- NCT05441683
- Testing
- horizontal extending incision, vertical releasing incision
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Surgical Incisions
LiquiBand Versus Dermabond Versus Sutures for Closure of Surgical Wounds
To evaluate the cosmetic outcome, effectiveness, user and subject satisfaction, and safety of LiquiBand® Flex in relation to DermaBond Advanced™ and conventional sutures for the topical closure of surgical wounds.
- Trial name
- NCT01835405
- Testing
- LiquiBand Flex, Dermabond Advanced, Sutures (Prolene)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Advanced Medical Solutions Ltd.
Colorectal Cancer, Nutritional Deficiency
PeRioperative Omega Three and the Effect on ImmuNity
Bowel cancer is the second most common cause of cancer-related death in the UK, with 50,000 new cases and over 15,000 deaths annually.
- Conditions
- Colorectal Cancer, Nutritional Deficiency, Infected Wound, Surgical Site Infection
- Trial name
- PROTEIN (NCT03598413)
- Testing
- Omega-3
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust