Clinical trials: Incision
Cesarean Section Complications, Wound Breakdown
Antimicrobial Dressing Versus Standard Dressing in Obese Women Undergoing Cesarean Delivery
This will be an open label pilot randomized controlled clinical trial. Women undergoing cesarean delivery will be randomized to have standard wound dressing care or chlorohexidine gluconate (CHG) impregnated wound dressing…
- Conditions
- Cesarean Section Complications, Wound Breakdown, Wound Infection, Satisfaction
- Trial name
- NCT03887299
- Testing
- ReliaTect™ Post-Op Dressing (contains chlorohexidine gluconate or CHG), Standard Wound Care
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Surgical Wound Dehiscence
A Study, Performed in Subjects With Post Traumatic-post Surgical ,Venus Insufficiency and Diabetic Hard to Heal/Chronic Wounds, to Evaluate the Safety and Efficacy of PolyHeal-2 Versus PolyHeal in Once Daily Regimen
This is a double-blind , randomized, controlled, two-arm study aiming to evaluate the safety and efficacy of Polyheal-2 vs PolyHeal, in once daily application as compared to historical control.
- Trial name
- NCT01679678
- Testing
- PolyHeal 2, Polyheal
- Where
- 4 sites in Israel
- Volunteers
- 15 people
- Sponsor
- MediWound Ltd
Surgical Wound Infection, Surgical Site Infection
Bacteriology of sUrGical Site INfection Following Surgery for Intestinal Failure
This is a prospective observational study of patients undergoing planned surgery for intestinal failure. The aims of the study are: To prospectively characterise preoperative bacterial populations amongst patients undergoing…
- Conditions
- Surgical Wound Infection, Surgical Site Infection, Bacteria Infection Mechanism, Intestinal Disease
- Trial name
- BUGS-IN-IF (NCT05234515)
- Testing
- Microbiology swab, Questionnaire
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- London North West Healthcare NHS Trust
Surgical Site Infections
Ampicillin/Sulbactam Versus Cefuroxime as Antimicrobial Prophylaxis for Cesarean Section
The efficacy and safety of a single dose of ampicillin/sulbactam compared to a single dose of cefuroxime at cord clamp for prevention of postcesarean infectious morbidity has not been assessed.
- Trial name
- NCT01138852
- Testing
- Ampicillin-sulbactam, Cefuroxime
- Volunteers
- 176 people
- Sponsor
- Attikon Hospital
Incisional Hernia of Midline of Abdomen
Laparoscopic IPOM Plus vs. eTEP Trial
The survey will compare primary and secondary outcomes of laparoscopic intraperitoneal onlay mesh (IPOM plus) and extended totally extraperitoneal (eTEP) repair for incisional hernia.
- Trial name
- NCT05528107
- Testing
- Lap IPOM plus, eTEP
- Where
- Russia
- Volunteers
- 72 people
- Sponsor
- City Clinical Hospital No.1 named after N.I. Pirogov
Surgical Site Infection
Air Barrier System for the Prevention of Surgical Site Infection
Airborne particles are present in all indoor environments including the operating room. Most of these particles come from the surgical staff moving around in the room, positioning of the patient during surgery, and the movement…
- Trial name
- ABS (NCT01610271)
- Testing
- Air Barrier System
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Nimbic Systems, LLC
Skin Closure of Surgical Incisions by Tissue Glue vs Suture
Tissue Glue (Cyanoacrylate) Versus Conventional Suture in Kidney Donors
By means of a prospective, randomised trial the investigators want to examine skin closure in living donors - subjected to laparoscopic, hand-assisted nephrectomy - by tissue glue (Cyanoacrylate (Liquiband)) versus conventional…
- Trial name
- TG-CYANO (NCT01521871)
- Testing
- Skin wound closure by tissue glue, Skin wound closure by conventional suture + dressing
- Where
- Norway
- Volunteers
- 64 people
- Sponsor
- Oslo University Hospital
Laparoscopic Cholecystectomy
Single Incision Versus Three Port Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy (LC) became the standard treatment for symptomatic gallbladder disease. Single incision laparoscopic surgery (SILS) was developed with the aim of reducing the invasiveness of conventional laparoscopy.
- Trial name
- NCT03067038
- Testing
- Single incision laparoscopic cholecystectomy, Three port laparoscopic cholecystectomy
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- South Valley University
Gingival Recession, Localized
Extended Platelet- Rich Fibrin Membrane Combined With Vestibular Incision Subperiosteal Tunnel Access Technique to Treat Localized Gingival Recession
This study will be performed to clinically evaluate and compare the effectiveness of extended platelet-rich fibrin (e-PRF) membrane versus de-epithelized free gingival graft (DFGG) in combination with vestibular incision…
- Trial name
- alb prf REC (NCT07079293)
- Testing
- Preparation of Extended PRF, Harvesting of Free Gingival Graft and preparation of CTG, VISTA technique
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Carpal Tunnel Syndrome
Comparison of Conventional Versus Transverse Mini-Incision Technique for Carpal Tunnel Release
This study aimed at to fill the gaps by comparing the surgical outcomes of the conventional versus transverse mini-incision technique for carpal tunnel syndrome in terms of pain and functional outcomes.
- Trial name
- NCT07018011
- Testing
- Conventional open CTR, Transverse mini-incision technique
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- RESnTEC, Institute of Research
Deep Neck Space Infections
Assessment of Clinical Outcomes in Closure of Deep Neck Space Infection Incisions
The purpose of this study is to determine if closure of deep neck infection incisions at the time of extraoral drain removal has any impact on rates of reinfection and to determine if this treatment will have any impact on scar…
- Trial name
- NCT04286087
- Testing
- neck incisions closed at bedside at the time of drain removal under local anesthesia, standard treatment
- Sponsor
- The University of Texas Health Science Center, Houston
Cardiac Event, Arrest; Cardiac, Complicating Surgery
Prevena Incision Management
The question this research project wants to explore is whether using the Prevena Incision Management System (Prevena) will improve sternal wound edge oxygenation in patients undergoing Coronary Artery bypass surgery with…
- Conditions
- Cardiac Event, Arrest; Cardiac, Complicating Surgery, Coronary Bypass Graft Stenosis, Complication of Coronary Artery Bypass Graft
- Trial name
- Prevena (NCT02814084)
- Testing
- Bilateral Internal Mammary Artery grafts, Prevena
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Skin Diseases, Surgical Site Infection
Effectiveness of Preoperative Surgical Scrubbing Using Clorhexidine Digluconate and Parachlorometaxylenol (ECP)
Despite the wide variety of products and antiseptic agents, no agent is ideal for every situation. The investigators would like to evaluate the difference in reducing bacterial load, using 4% chlorhexidine digluconate and 3%…
- Trial name
- ECP (NCT02500758)
- Testing
- Preparatory handwash, Preoperative surgical scrubbing using 3% PCMX, Preoperative surgical scrubbing using 4% CHG
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ricardo Becerro de Bengoa Vallejo
Breast Cancer, Breast Reconstruction
Closed Incision Disposable Negative Pressure Wound Therapy in Immediate Postmastectomy Breast Reconstruction
The study aimed to assess the impact of the use of closed incision negative pressure wound therapy (ciNPWT) after immediate breast reconstruction on the number of surgical-site complications, skin surface temperature, objective…
- Trial name
- NCT04808765
- Testing
- Immediate Breast reconstruction
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- University in Zielona Góra
Cataract
Comparison of Wound Integrity for Clear Corneal Cataract Incisions
This is a randomized controlled trial to evaluate the safety and efficacy of two different closing methods for clear corneal cataract incisions
- Trial name
- NCT05242653
- Testing
- pressure by a cotton swab, stromal hydration with the balanced salt solution（BSS）
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Surgical Wound Infection
Alexis O-Ring Wound Retractor for the Prevention of Post-cesarean Surgical Site Infections
Post cesarean section surgical site infection (SSI) is a common complication that can affect patient recovery and overall outcome.
- Trial name
- Alexis (NCT03365219)
- Testing
- Alexis O-Ring Wound Retractor, Standard Surgical Retractors
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia
Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.
Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Feasibility Study on Nitropaste Using Intraoperative SPY Imaging.
- Conditions
- Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia, Tibial Plateau Fracture, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)
- Trial name
- SPY NITROPASTE (NCT07004764)
- Testing
- Nitroglycerin Ointment 2%
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University
Surgical Site Infections, Post Operative Complication
2% Chlorhexidine Gluconate Skin Cloths to Prevent SSI in Spine Surgery Patients
Surgical site infection (SSI) following spinal surgery is a frequent complication and results in higher morbidity, mortality and healthcare costs.
- Trial name
- DeSSI (NCT02490631)
- Testing
- 2% chlorhexidine gluconate cloths
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Vanderbilt University
Residual Limb Pain, Stump Pain
Post-Amputation Stump Infection as a Predictor of Persistent Residual Limb Pain: A Prospective Cohort Study
Persistent residual limb pain is common after traumatic amputation and significantly impairs rehabilitation and prosthetic use. Postoperative stump infection may contribute to peripheral nerve sensitization, scar fibrosis, and…
- Conditions
- Residual Limb Pain, Stump Pain, Post-Amputation Pain, Surgical Site Infection
- Trial name
- INF-STUMP-PAIN (NCT07438795)
- Volunteers
- 150 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Neoplasms
Efficacy and Safety of FLEXIPORT Implantable Port in Chemotherapeutic Treatments
The goal of this clinical trial is to assess, in a clinical setting, the efficacy and the safety of FLEXIPORT, a totally implantable venous access device (TIVAD) designed to provide a repeated access to the vascular system, in…
- Trial name
- PTC (NCT07856745)
- Testing
- FLEXIPORT
- Where
- Dominican Republic
- Volunteers
- 40 people
- Sponsor
- Portal Access Ltd.