Clinical trials: Incision Infection
Wounds and Injuries, Wound Infection
Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds
This study will evaluate the use of free autologous dermal fat grafting (also called free dermal fat autografting) to treat complex craniofacial wounds that have failed standard treatment and to understand how well these grafts…
- Conditions
- Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries
- Trial name
- FTFDT2 (NCT03880188)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dufresne, Craig, MD, PC
Cardiac Surgery
Prevention of Surgical Wound Infection
To compare cost effectiveness of a polyurethane dressing or a vacuum therapy dressing versus the conventional gauze in the prevention of superficial wound infection y major cardiac surgery
- Trial name
- NCT03905213
- Testing
- dressing MEPORE, dressing MEPILEX, dressing PICCO
- Volunteers
- 900 people
- Sponsor
- Maria Jesus Perez
Surgical Site Infection
Supplemental Oxygen and the Risk of Surgical Site Infection
This is a study to see whether increasing the oxygen concentration during and after a cesarean section decreases the infection rate.
- Trial name
- PORSSI (NCT00876005)
- Testing
- Oxygen by mask
- Where
- United States
- Volunteers
- 1,202 people, healthy volunteers welcome
- Sponsor
- Santa Clara Valley Health & Hospital System
ExtraCorporeal Membrane Oxygenation (ECMO), Wound Complications
Closed Incision NPWT to Prevent Wound Complications Post-ECMO
Patients undergoing extracorporeal membrane oxygenation (ECMO) are at increased risk of wound complications at the vascular access site after decannulation. These complications may delay recovery and increase healthcare burden.
- Conditions
- ExtraCorporeal Membrane Oxygenation (ECMO), Wound Complications, Surgical Site Infection (SSI)
- Trial name
- PREVENT-ECMO (NCT07709546)
- Testing
- Prophylactic Closed-Incision Negative Pressure Wound Therapy, Standard Wound Dressing
- Volunteers
- 144 people
- Sponsor
- St. Antonius Hospital
Colon Cancer
Intracorporeal Anastomosis Versus Extracorporeal Anastomosis for Left Colon Cancer
This study aims to investigate the effects of intracorporeal anastomosis and extracorporeal anastomosis in laparoscopic-assisted radical left hemicolectomy on surgical site infection.
- Trial name
- NCT04201717
- Testing
- laparoscopic assisted left colectomy (extracorporeal anastomosis group), total laparoscopic left colectomy (intracorporeal anastomosis group)
- Where
- 12 sites in China
- Volunteers
- 350 people
- Sponsor
- Jilin University
Surgical Site Infection
Gaps Between Evidence and Practice in Prevention of Surgical Site Infection in Spain
Web-based survey to members of 10 Spanish Associations of surgical nurses and surgeons of different specialities to know the application of preventative measures for surgical site infection.
- Trial name
- SurveyOIC (NCT04310878)
- Testing
- Survey among perioperative nurses and surgeons
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Hospital de Granollers
Post Operative Surgical Site Infection
Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA
The overall objective is to compare the effect of Vancomycin and Tobramycin powder combined (treatment) to Vancomycin powder (control) in the reduction of post-fixation infections of tibial plateau and tibial pilon fractures at…
- Trial name
- TOBRA (NCT04597008)
- Testing
- Treatment group, Control group
- Where
- 41 sites in United States
- Volunteers
- 1,660 people
- Sponsor
- Major Extremity Trauma Research Consortium
Surgical Site Infection After Major Surgery
Effect of High Dose Insulin on Infectious Complications Following Major Surgery
Despite improvements in surgical techniques and perioperative care, the high incidence of postoperative surgical site infections remains a major problem in patients undergoing major abdominal surgery (liver, pancreatic and…
- Trial name
- NCT01528189
- Testing
- Hyperinsulinemic normoglycemic clamp, Standard glucose management
- Where
- 3 sites in Canada, Chile
- Volunteers
- 480 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Rectal Cancer, Organ-Space Surgical Site Infection
Organ/Space Surgical Site Infection and Recurrence and Survival in Rectal Cancer Surgery
In rectal cancer surgery, the organ/space surgical site infection (O/S-SSI) has an impact on patient's prognosis. Its influence in the oncologic outcomes remains controversial.
- Trial name
- VINCat_PDO_2 (NCT06382415)
- Where
- Spain
- Volunteers
- 3,826 people
- Sponsor
- Hospital de Granollers
Surgical Site Infections
Efficacy Study of Mupirocin on Infection After Coronary Artery Bypass Grafting
The hypothesis is that application of Mupirocin to the nose before and after coronary artery bypass grafting surgery will reduce the incidence of surgical site infections.
- Trial name
- MIR-CABG (NCT01949935)
- Testing
- Mupirocin
- Where
- Canada
- Volunteers
- 974 people
- Sponsor
- Horizon Health Network
Surgical Site Infection, Vancomycin
Pharmacokinetics of Preoperative Vancomycin
A study of plasma and tissue vancomycin pharmacokinetics in pediatric surgical patients.
- Trial name
- NCT03453684
- Testing
- Administration of Vancomycin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Liver Transplant Infection, Surgical Site Infection
Pharmacological Study of Cefazolin Antibioprophylaxis in Liver Transplantation
This study describes Cefazolin pharmacokinetics variation to target levels during liver transplantation.
- Conditions
- Liver Transplant Infection, Surgical Site Infection, Antibiotic Prophylaxis, Cephazolin Adverse Reaction
- Trial name
- ProCeTH (NCT04280237)
- Testing
- Blood samples
- Where
- France
- Sponsor
- University Hospital, Tours
Surgical Site Infection, Vaginal Cuff Cellulitis
Prevention of Vaginal Cuff Infection After Hysterectomy by Addition of Vaginal Clindamycin
This study seeks to determine ways to reduce the hospitals surgical site infection rate during hysterectomy operations.
- Conditions
- Surgical Site Infection, Vaginal Cuff Cellulitis, Bacterial Vaginosis
- Trial name
- NCT07888101
- Testing
- Clindamycin Vaginal Gel
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Baylor Research Institute
Surgery, Surgical Site Infection
Efficacy of an Intervention to Improve the Preoperative Shower in Scheduled Surgery
The aim of the project is to evaluate the effectiveness, on the skin cleanliness of the patient on arrival at the operating room, of an intervention aimed at improving the performance of the preoperative shower, for patients…
- Trial name
- PRODOUCH'OP (NCT04820075)
- Testing
- improvement of preoperative shower
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Rouen
Surgical Site Infection
Evaluation of Peri-operative Risk Factors for Surgery Site Infection in Cardiac Surgery
There is a recent increase in incidence of surgical site infection after cardiac surgery in our hospital, in spite of specific measures taken concerning some aspects of the surgical procedures, targeting a better control of the…
- Trial name
- PRISCCA (NCT02392936)
- Testing
- Sternotomy for coronary artery bypass graft, valvuloplasty, aortic surgery or combined procedures, under extracorporeal circulation or not, in emergency or scheduled.
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Orthopedic Disorder, Incision Infection
Study on the Preventive Effect of Establishing an Integrated Working Group of Doctors and Nurses in Operating Room
To explore the preventive effect and clinical enlightenment of establishing an integrated working group of doctors and nurses in operating room on incision infection in orthopedic surgery.
- Trial name
- NCT06579599
- Testing
- an integrated working group nursing
- Where
- China
- Volunteers
- 130 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Metastatic Disease, Spinal Cord Injury
Negative Pressure Wound Therapy vs. Sterile Dressing for Patients Undergoing Thoracolumbar Spine Surgery
The purpose of this study is to determine if the use of the Prevena™ System decreases the rate of subcutaneous seroma, superficial wound dehiscence and infection.
- Conditions
- Metastatic Disease, Spinal Cord Injury, Spinal Degeneration, Spinal Deformity
- Trial name
- NCT03632005
- Testing
- Vacuum Assisted Closure, Sterile dressing
- Where
- Canada
- Volunteers
- 550 people
- Sponsor
- John Street
Prosthetic-joint Infection, Dysbiosis
Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and Knee
Prosthetic joint infection (PJI) is one of the most devastating complications following total joint arthroplasty (TJA) of the hip and knee. Standard of care (SOC) treatment includes surgery and antimicrobials.
- Trial name
- NCT06636669
- Testing
- Probiotic, Standard of care
- Where
- 2 sites in United States
- Volunteers
- 152 people
- Sponsor
- Boston Medical Center
Arterial Obstructive Diseases
Trial Using Integuseal as Microbial Sealant for Arterial Bypass Surgery on Lower Extremities
The purpose of this study is to prove a reduction of postoperative wound infections after direct preoperative use of a microbial sealant in the form of Integuseal for vascular procedures on lower extremities.
- Trial name
- ITT (NCT00940979)
- Testing
- Application of Integuseal sealant
- Where
- 3 sites in Netherlands
- Volunteers
- 450 people
- Sponsor
- Rijnstate Hospital
Drug Resistance, Bacterial, Postoperative Wound Infection
Local Collagen-Gentamicin and Extra Fixation of the Sternum for Prevention of Sternal Wound Infection in Cardiac Surgery
The aim of the present study is to evaluate a new technique for prevention of sternal wound infection consisting of local application of collagen-gentamicin in addition to routine i.v. antibiotic prophylaxis.
- Trial name
- LOGIX (NCT00484055)
- Testing
- Local application of collagen-gentamicin, Fixation of the sternotomy with more than six wires
- Where
- 2 sites in Sweden
- Volunteers
- 1,358 people
- Sponsor
- Region Örebro County