Clinical trials: Incision Infection
Surgical Site Infections, Lumbar Spinal Fusion
Adhesive Strips Vs Sutures in Skin Closure for Lumbar Spinal Fusion
Comparison between two methods for skin closure in lumbar spinal fusion surgery, a non-inferiority approach between sutures and adhesive strips and its effect on surgical site infections.
- Trial name
- NCT06664424
- Where
- Germany
- Volunteers
- 1,016 people
- Sponsor
- Diakonie-Klinikum Stuttgart
Surgical Site Infections, Infections
Light-Activated Antimicrobial Therapy to Prevent Surgical Site Infections - Canada
This is a Phase 4 multi-center, group-randomized, crossover trial to compare nasal antimicrobial photodisinfection therapy (aPDT) with standard of care for prevention of surgical site infections in patients undergoing major…
- Conditions
- Surgical Site Infections, Infections, Surgical Wound Infections, Anti-Infective Agents
- Trial name
- LANTERN (NCT07189858)
- Testing
- Nasal antimicrobial photodisinfection therapy
- Where
- 4 sites in Canada
- Volunteers
- 401 people
- Sponsor
- Ondine Biomedical Inc.
Colostomy
Pursestring Wound Closure vs "Gunsight" Skin Incision and Closure Technique to Reverse Stoma
The use of temporary stomas has been demonstrated to reduce septic complications after colorectal cancer surgery, especially in high-risk anastomosis; therefore, it is necessary to reduce the number of complications secondary to…
- Trial name
- GSICT1126 (NCT02053948)
- Testing
- Pursestring Wound Closure, Gunsight Skin Incision and Closure Technique
- Where
- China
- Volunteers
- 143 people
- Sponsor
- Beijing Chao Yang Hospital
Surgical Site Infection
Use of 2% Chlorhexidine Cloths Reduce Surgical Site Infections
Use of 2% chlorhexidine gluconate cloths pre-operatively and daily post-operatively jaw line to toes will decrease surgical site infections (SSI) by 30% when compared to patients who receive routine standard of care (use of…
- Trial name
- NCT02385708
- Testing
- 2% Chlorohexidine Gluconate Standard of Care, 2% Chlorohexidine Gluconate Chin to Toe
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- Vanderbilt University
Colorectal Surgery, Surgical Wound Infection
A Study of an Antibiotic Implant in General Surgical Subjects at Higher Risk for Surgical Wound Infection
The purpose of this study is to determine whether the gentamicin-collagen sponge is safe and effective for preventing surgical wound infections in patients undergoing colorectal surgery.
- Trial name
- NCT00600925
- Testing
- gentamicin-collagen sponge dipped in saline
- Where
- 39 sites in United States
- Volunteers
- 602 people
- Sponsor
- Innocoll
Postoperative Complications, Postoperative Wound Infection
Influence of Deep Versus Moderate Neuromuscular Blockade During General Anesthesia on 30-day Readmission Rates
Deep neuromuscular block (NMB) has shown to produce superior surgical conditions during various abdominal and non abdominal surgeries.
- Conditions
- Postoperative Complications, Postoperative Wound Infection, Pneumonia
- Trial name
- NCT03174223
- Testing
- deep neuromuscular block
- Where
- Netherlands
- Volunteers
- 460 people
- Sponsor
- Leiden University Medical Center
Total Knee Replacement Surgery
Iodine Impregnated Incision Drapes and Bacterial Recolonization in Simulated Knee Surgery. A Controlled Randomized Experimental Trial.
This study evaluates the effect of Iodine-impregnated self-adhesive plastic drapes (IIAD) on the quantity of skin bacteria, which is a known factor in the development of surgical site infections in orthopedic surgery.
- Trial name
- NCT02342561
- Testing
- Ioban 2 incision drape, 3M
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Odense University Hospital
Bacterial Infections, Surgical Site Infection
RBG: Regular, Bare, Gel: Does Type of Nail Polish Affect Bacterial Counts After Surgical Scrubbing?
Purpose: The purpose of this study is to evaluate if type of nail polish (gel polish or regular polish) has an effect on the number of bacterial colonies on finger nails after surgical scrubbing.
- Conditions
- Bacterial Infections, Surgical Site Infection, Contaminated Medical or Biological Substances
- Trial name
- RBG (NCT05210920)
- Testing
- Nail polish application
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Surgical Site Infection
Surgical Site Infection in Caesarean Section Using Alexis O Compared to Metal Retractors
Objective: To investigate if the use of the newly designed Alexis O Retractor leads to improved intra-operative and post-operative surgical outcomes in the setting of planned elective Caesarean Sections.
- Trial name
- NCT02685696
- Testing
- Alexis O Retractor, Metal Retractor
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Surgical Wound Infection
Trial to Reduce Wound Infection With Contralateral Drainage in Loop Ileostomy Closure
1. Introduction: The most common complication of loop ileostomies closure for rectal cancer patients undergoing a low anterior rectum resection, is the superficial surgical site infection (incidence 2-40%).
- Trial name
- NCT02574702
- Testing
- application of a contralateral drainage (Penrose ® device)
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Corporacion Parc Tauli
Surgery, Surgical Site Infection
Efficacy of an Intervention to Improve the Preoperative Shower in Scheduled Surgery
The aim of the project is to evaluate the effectiveness, on the skin cleanliness of the patient on arrival at the operating room, of an intervention aimed at improving the performance of the preoperative shower, for patients…
- Trial name
- PRODOUCH'OP (NCT04820075)
- Testing
- improvement of preoperative shower
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Rouen
Peripheral Artery Disease, Critical Limb Ischemia
Comparison of Prevena Negative Pressure Incision Management System vs. Standard Dressing After Vascular Surgery
The purpose of this study is to evaluate the effectiveness of negative pressure incision management system (Prevena™ Incision Management System (PIMS) or ActiVAC® with the Prevena™ Dressings (Peel and Place™ or Customizable™)…
- Conditions
- Peripheral Artery Disease, Critical Limb Ischemia, Claudication
- Trial name
- NCT02389023
- Testing
- standard gauze dressing, Prevena Incision Management system
- Where
- 5 sites in United States
- Volunteers
- 242 people
- Sponsor
- University of Vermont Medical Center
Stomach Neoplasms
No Antimicrobial Prophylaxis for Laparoscopic Distal Gastrectomy
The aim of this study is to evaluate the feasibility and safety of no use of antimicrobial prophylaxis during laparoscopic distal gastrectomy for gastric carcinoma.
- Trial name
- KSWEET-01 (NCT02200315)
- Testing
- No Antimicrobial prophylaxis
- Where
- 3 sites in South Korea
- Volunteers
- 98 people
- Sponsor
- Korean South West East Gastric Surgery Group
Surgical Site Infection, Surgical Wound Infection
Antibacterial-coated Sutures at Time of Cesarean
Abdominal closure with antibacterial-coated sutures has been shown to reduce wound infections after a number of surgical procedures, but none of the previous trials included cesarean delivery.
- Conditions
- Surgical Site Infection, Surgical Wound Infection, Cesarean Section; Infection, Cesarean Section Complications
- Trial name
- ASTC (NCT03386240)
- Testing
- Vicryl-plus, monocryl-plus, PDS-plus (Triclosan-coated Sutures), Vicryl, monocryl, PDS (not coated with triclosan)
- Where
- United States
- Volunteers
- 1,169 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Colorectal Neoplasms, Diverticulitis
Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery
This randomized clinical trial studies how well neomycin and metronidazole hydrochloride with or without polyethylene glycol work in reducing infection in patients undergoing elective colorectal surgery.
- Conditions
- Colorectal Neoplasms, Diverticulitis, Inflammatory Bowel Diseases, Surgical Site Infection
- Trial name
- NCT03042091
- Testing
- Polyethylene Glycol, Neomycin, Metronidazole Hydrochloride
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Thomas Jefferson University
Surgical Site Infection
Skin Staples vs Polypropylene in Elective Laparotomy
Surgical site infection (SSI) is one of the most common postoperative complications following elective laparotomy and contributes significantly to patient morbidity, prolonged hospital stay, and increased healthcare costs.
- Trial name
- NCT07781878
- Testing
- Skin staples, Polypropylene skin suture
- Where
- Pakistan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Pakistan Institute of Medical Sciences
Postoperative Surgical Site Infections
Negative Pressure Wound Therapy Use to Decrease Surgical Nosocomial Events in Colorectal Resections
The purpose of this study is to determine, in patients who undergo an elective colorectal resection through a midline laparotomy incision, whether the use of negative pressure wound therapy (NPWT) applied to the site of the…
- Trial name
- NEPTUNE (NCT02007018)
- Testing
- Negative Pressure Wound Therapy, Usual Care of Surgical Wound
- Where
- 2 sites in Canada
- Volunteers
- 300 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Wound Complication, Wound Heal
Immunonutrition and Carbohydrate Loading Strategies in Breast Reconstruction
This study is designed to test the following hypothesis: patients undergoing immediate alloplastic and autologous breast reconstruction following mastectomy that receive preoperative immunonutrition will experience a reduction in…
- Conditions
- Wound Complication, Wound Heal, Complications Wound, Surgical Wound Infection
- Trial name
- NCT03764943
- Testing
- Impact Advanced Recovery
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Wisconsin, Madison
Colorectal Neoplasms, Surgical Wound Infection
Reduction of Surgical Site Infections in Elective Colorectal Surgery After the Implementation of a Bundle of Care.
Background. The Nosocomial Infection Surveillance Program in Catalonia (VINCat) monitors SSI in elective colorectal surgery since 2007 in 56 hospitals (7.5 million population).
- Trial name
- NCT04129177
- Testing
- Implementation of a bundle of surgical infection preventive measures
- Where
- Spain
- Volunteers
- 12,000 people
- Sponsor
- Hospital de Granollers
Surgery, Surgical Site Infection
SURGX Antimicrobial Gel Versus Povidone-iodine Skin Incision Prep in Total Shoulder Arthroplasty
Comparing the growth of intra-operative tissue cultures of Cutibacterium Acnes after primary shoulder replacement when using a no-prep control group versus antimicrobial wound gel versus betadine applied to the skin layer after…
- Conditions
- Surgery, Surgical Site Infection, Cutibacterium Acnes, Prosthetic-joint Infection
- Trial name
- NCT05919888
- Testing
- Povidone-Iodine, SURGX Wound Gel
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- St. Louis University