Clinical trials: Incision Infection
Total Hip and Knee Arthroplasties
Teicoplanin Prophylaxis for Total Hip or Knee Arthroplasty
This is a prospective, open-label, randomized clinical trial where patients were administered prophylaxis for total hip or knee arthroplasty either with teicoplanin or with other antibiotics.
- Trial name
- NCT00719056
- Testing
- Teicoplanin, β-lactams or ciprofloxacin
- Where
- 3 sites in Greece
- Volunteers
- 616 people
- Sponsor
- University of Athens
Surgical Site Infection
Efficacy of NPWT in Reducing the Incidence of Wound Infection After Pancreatic Surgery
A disposable negative wound pressure device will be compared to standard sterile wound dressing in reducing the rate of wound infection after clean-contaminated surgical procedures on biliary tract and pancreas in patients at…
- Trial name
- NCT03700086
- Testing
- Disposable negative wound pressure device (PICO), OPsite post-op visible standard sterile dressing
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Colorectal Cancer
Difference of Surgical Site Infection Between Using Sodium Picosulfate Solution(PicosolutionⓇ) and Oral Sulfate Tablet(ORA·FANGⓇ) in Colorectal Cancer Surgery
This is a prospective randomized study to evaluate the difference in the rate of surgical site infection between the patients who used Sodium Picosulfate solution(PicosolutionⓇ) and tablet Oral Sulphate Solution(ORA·FANGⓇ) for…
- Trial name
- NCT04593446
- Testing
- Oral Sulfate Tablet(ORA·FANGⓇ), Sodium Picosulfate Solution(PicosolutionⓇ)
- Where
- South Korea
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Acute Appendicitis
The Comparison of Single Incision Laparoscopic Appendectomy and Three Port Laparoscopic Appendectomy
Laparoscopic techniques have allowed surgeons to perform complicated intrabdominal surgery with minimal trauma. In numerous studies, when conventional laparoscopic appendectomy using 3 ports is compared with open appendectomy, it…
- Trial name
- NCT01816568
- Testing
- SILS appendectomy, Three port laparoscopic appendectomy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Surgery, Incisional Hernia
Suture Techniques to Reduce the Incidence of Incisional Hernia: LTFU STITCH Trial
Rationale: Incisional hernias (IH) are a frequent complication after abdominal surgery. Prevalence of an IH varies depending on the previous abdominal procedure but could be as high as 70% in high-risk patients after open…
- Conditions
- Surgery, Incisional Hernia, Wound Infection, Fascial Dehiscence
- Trial name
- LTFU-STITCH (NCT06066385)
- Testing
- Small bites technique, Conventional large bites closure
- Where
- 9 sites in Netherlands
- Volunteers
- 560 people
- Sponsor
- Erasmus Medical Center
Surgical Site Infection, Skin Colonization
Dressing Wear Time After Reduction Mammaplasty
This study was designed to determine whether the duration of dressing wear following reduction mammaplasty influence skin colonization and surgical site infections rates.
- Trial name
- NCT01002391
- Testing
- reduction mammaplasty
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Daniela Francescato Veiga
Cesarean Section Complications, Vaginal Infection
Vaginal Cleaning Using Povidone Iodine Before CS to Reduce Postoperative Wound Infection
The aim of work to assess the effectiveness of preoperative vaginal cleansing with povidone iodine on reduction of post caesarean section wound infection Research questions: Does vaginal cleaning using povidone iodine before…
- Conditions
- Cesarean Section Complications, Vaginal Infection, Postoperative Infection
- Trial name
- NCT05021315
- Testing
- 10% povidone iodine
- Where
- 2 sites in Egypt
- Volunteers
- 800 people
- Sponsor
- Cairo University
Surgical Site Infection, Surgical Wound
Optimizing Closed Incision Negative Pressure Wound Therapy in Emergency Laparotomy
The purpose of this study is to find differences in rates of surgical site infections following emergency laparotomy with the use of two different incisional negative pressure wound therapy (iNPWT)devices.
- Conditions
- Surgical Site Infection, Surgical Wound, Surgical Wound Infection, Surgical Complication
- Trial name
- OPTIWOUND (NCT05716490)
- Testing
- Incisional negative pressure wound therapy, Control group - standard wound dressing
- Where
- Portugal
- Volunteers
- 114 people
- Sponsor
- Centro Hospitalar do Tâmega e Sousa
Surgical Site Infection (SSI)
Continuous Infusion Versus Intermittent IV Bolus of Cefazolin: Prevention of Surgical Site Infection During Orthopedic Surgeries in Egyptian Patients.
A randomized controlled trial on adults who underwent orthopedic surgery. To evaluate the effectiveness of intraoperative continuous infusion (CI) of cefazolin compared with intermittent (INT) cefazolin administration in…
- Trial name
- NCT07655596
- Testing
- Cefazolin 2 g Infusion, Cefazolin 2 GM Injection
- Volunteers
- 100 people
- Sponsor
- Helwan University
Skin Cancer
ObservAtional Study to Investigate Surgical Site Infection in Ulcerated Skin Cancers
The investigators aim to recruit 311 participants to this study from three UK Dermatology departments. The investigators will invite people with suspected skin cancers whose lesions have a broken surface (also known as ulcerated)…
- Trial name
- OASIS (NCT03782727)
- Where
- 3 sites in United Kingdom
- Volunteers
- 148 people
- Sponsor
- Cardiff and Vale University Health Board
Surgical Site Infection
Surgical-Site Infection After Laparoscopic Right Colectomy
Laparoscopic right colectomy with intracorporeal anastomosis seems to be associated with several short-term benefits. It could reduce the postoperative infection rate and shorten the hospital stay.
- Trial name
- NCT04350203
- Testing
- Laparoscopic right colectomy with intracorporeal anastomosis (IA), Laparoscopic right colectomy with extracorporeal anastomosis (EA)
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Hospital Plató
Osteomyelitis Tibia, Surgical Site Infection
Acute Posttraumatic Osteomyelitis in Patients With High-energy Tibial Fractures and Biomarkers
The present trial was aimed to identify which biomarkers could be associated in perioperative period after surgical treatment of tibial fracture to the development of POM.
- Trial name
- POMTIBIAL (NCT03459261)
- Testing
- blood sample on admission (ADD), first postoperative day (POD1) and fourth postoperative day (POD4)
- Volunteers
- 86 people
- Sponsor
- University Medical Centre Ljubljana
Surgical Site Infection
Prevention of Surgical Site Infections: Effectiveness of Nasal Povidone-Iodine and Nasal Mupirocin
We hypothesize the application of mupirocin or povidone-iodine to the nares is equally effective in short term Staphylococcus aureus(SA)suppression.
- Trial name
- NCT01313182
- Testing
- mupirocin calcium ointment, 2%, 3M Skin and Nasal Antiseptic
- Where
- United States
- Volunteers
- 1,874 people
- Sponsor
- Solventum US LLC
Appendicitis
Role of Wound Irrigation After Appendectomy
Surgical site infection is a common problem after open appendectomy. Irrigation of the surgical wound by topical antibiotics has been devised as a measure to reduce the incidence of wound infection.
- Trial name
- NCT03773224
- Testing
- Irrigation
- Where
- Egypt
- Volunteers
- 179 people
- Sponsor
- Mansoura University
Surgical Infection
Routine Preoperative Antibiotic Prophylaxis in Modified Radical Mastectomy
This is a randomized, double blinded, placebo-controlled trial on the routine use of preoperative antibiotic prophylaxis in modified radical mastectomy to evaluate the efficacy of preoperative prophylactic antibiotics in the…
- Trial name
- NCT01558986
- Testing
- Cefazolin, Sterile water
- Where
- Philippines
- Volunteers
- 254 people
- Sponsor
- University of the Philippines
Surgical Site Infection
Novosyn® CHD vs Polyglactin 910 Suture to Close Wounds After Emergency or Elective Laparotomy or Laparoscopic Surgery
The aim of the study is to elucidate, if the colonization of bacteria is lower on the Novosyn® CHD suture compared to uncoated Polyglactin 910 suture, which will be assessed by the incidence of surgical site infections (SSI: A1…
- Trial name
- POLYNOVO-CHD (NCT05966961)
- Testing
- Novosyn® in emergency or elective laparotomy or laparoscopic surgery, Polyglactin 910 in emergency or elective laparotomy or laparoscopic surgery
- Where
- 4 sites in Italy, Spain
- Volunteers
- 2,998 people
- Sponsor
- Aesculap AG
Surgical Site Infection
Effect of Vitamin E-containing Dressing on Surgical Site Infection in Colorectal Surgery
A prospective, randomized study will be performed. Patients are randomized using a 1:1 allocation into 2 groups: patients receiving a vitamin E-containing dressing (group 1) and a conventional dressing (group 2).
- Trial name
- NCT03443141
- Testing
- Vitamin E, Standard dressing
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital General Universitario Elche
Surgical Wound, Wound Healing Delayed
Using AI Within Digital Wound Monitoring of Surgical Wounds to Prioritise Non-healing Wounds for Urgent Review
The goal of this clinical trial is to learn if artificial intelligence within digital wound monitoring of surgical wounds can prioritise non-healing wounds for urgent review in patients having first/redo CABG surgeries with or…
- Conditions
- Surgical Wound, Wound Healing Delayed, Heart; Surgery, Heart, Functional Disturbance as Result
- Trial name
- WISDOM (NCT06475703)
- Testing
- Isla wound prioritisation module, Standard follow-up
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Surgical Incision, Surgical Site Infection
Comparison of the Classical Median Sternotomy Skin Incision with the Paramedian Flap Skin Incision
The goal of this observational study is to determine the effects of a flap-shaped paramedian skin incision on protection from mediastinal infections, wound healing, and scar formation in open heart surgery performed through the…
- Conditions
- Surgical Incision, Surgical Site Infection, Keloid Scar Following Surgery
- Trial name
- NCT06725472
- Testing
- Open Heart Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ataturk University
Site Infection
Incidence of Ssi After c.s
aim of the work is to evaluate adherence to preoperative , intraoperative, and postoperative infection preventive measures during cesarean section and to assess it s impact on the incidence of surgical site infection and maternal…
- Trial name
- NCT07476261
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Assiut University