Clinical trials: Incision Infection
Laparoscopic Surgery, Surgical Wound
Triclosan-antibacterial Sutures Impact on the Incidence of Surgical Site Infection in Laparoscopic Surgeries.
Comparing the incidence of PSI in cases using coated Polyglactin 910 suture with Triclosan and cases using Polyglactin 910 suture without Triclosan in laparoscopic sleeve gastrectomy, laparoscopic appendectomy or laparoscopic…
- Conditions
- Laparoscopic Surgery, Surgical Wound, Surgical Site Infection
- Trial name
- NCT04255927
- Testing
- Coated Vicryl plus, Coated vicryl
- Where
- Egypt
- Volunteers
- 912 people
- Sponsor
- ClinAmygate
Surgical Site Infection
Evaluation of Peri-operative Risk Factors for Surgery Site Infection in Cardiac Surgery
There is a recent increase in incidence of surgical site infection after cardiac surgery in our hospital, in spite of specific measures taken concerning some aspects of the surgical procedures, targeting a better control of the…
- Trial name
- PRISCCA (NCT02392936)
- Testing
- Sternotomy for coronary artery bypass graft, valvuloplasty, aortic surgery or combined procedures, under extracorporeal circulation or not, in emergency or scheduled.
- Volunteers
- 1,000 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Surgical Site Infection
Prophylactic Antibiotic in Subtalar Fusion Surgery
Assessment of surgical site infection when using postoperative antibiotic prophylaxis in subtalar fusion surgery 24hours versus 5 days
- Trial name
- NCT06527989
- Testing
- Ceftriaxone 2000 mg
- Volunteers
- 102 people
- Sponsor
- Assiut University
Surgical Wound Infection
Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection
This prospective study evaluates the role of negative pressure wound therapy or wound VAC as a dressing over the incision to prevent poststernotomy wound infection in high risk patients.
- Trial name
- NCT02020018
- Testing
- Prevena Incision Management System, Conventional sterile dry wound dressing
- Where
- United States
- Volunteers
- 1,869 people
- Sponsor
- Mayo Clinic
Arthroplasty, Hip Replacement, Infection, Postoperative Wound
Efficacy of Surgical Skin Preparation Solutions in Hip Arthroplasty Surgery
This study will assess the efficacy of two of the most commonly used surgical skin-preparation solutions: Chloraprep (chlorhexidine-alcohol) and Duraprep (iodine-alcohol) at eliminating bacteria from the hip site by evaluating…
- Trial name
- NCT03393819
- Testing
- DuraPrep, ChloraPrep
- Volunteers
- 105 people
- Sponsor
- Lakehead University
Surgical Wound, Post Operative Wound Infection
Early Versus Delayed Bathing of Orthopaedic Surgical Wounds
This is a single center randomized control trial assessing the effect of early versus delayed bathing on orthopaedic surgical wounds in patients undergoing surgical treatment of fractures.
- Trial name
- EVDB (NCT06014411)
- Testing
- Time to bathing (delayed), Time to bathing (early)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Hospital for Special Surgery, New York
Surgical Site Infection (SSI), Spine Diseases
Efficacy of Intrawound Vancomycin in Spine Surgery
"This multicenter, prospective, time-cluster randomized controlled trial with blinded endpoint assessment (PROBE design) evaluated the efficacy of intrawound vancomycin powder (2 g) in preventing surgical site infections (SSI)…
- Trial name
- NCT07866157
- Testing
- vancomycin, Standard surgical closure
- Where
- Egypt
- Volunteers
- 416 people
- Sponsor
- Ain Shams University
Diabetic Foot Ulcer, Venous Leg Ulcer
PLASOMA Ultimate Safety & Efficacy Study
The purpose of the PULSE study are the followingL A.To perform post market clinical follow up (PMCF) on safety and efficacy: 1. Safety: To confirm transient short-terms side effects and verify long-term/outstanding risks. 2.
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Burn Wound
- Trial name
- PULSE (NCT04828304)
- Testing
- PLASOMA
- Where
- 6 sites in Netherlands
- Volunteers
- 101 people
- Sponsor
- Plasmacure
Orthognathic Surgical Site Infection
Antibiotics for Prevention of Infection Following Orthognathic Surgery
Orthognathic surgery describes a group of procedures aimed at correcting developmental or acquired deformities of the jaws and facial skeleton.
- Trial name
- NCT05852158
- Testing
- Cefazolin 2 GM Injection, Cefazolin Injection
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Abdul El-Rabbany
Surgical Wound Infection
NPWT in Patients Undergoing Surgical Procedures for Management of GI Malignancies
This randomized trial will use a Negative Pressure Wound Therapy device or standard wound closure, in participants with gastrointestinal neoplasms, to measure the rate of surgical site infections
- Trial name
- NCT04955730
- Testing
- Negative Pressure Wound Therapy
- Where
- United States
- Volunteers
- 290 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Colon Cancer, Rectal Cancer
Comparison of Two Bundles of Care to Reduce Surgical Site Infection in Colorectal Surgery (CCR-VINCat 2)
There is controversy about the maximum number of elements to be included in a surgical site infection (SSI) prevention bundle and the possibility of its implementation at a multi-center level.
- Conditions
- Colon Cancer, Rectal Cancer, Surgical Site Infection
- Trial name
- CCR-VINCat2 (NCT06244836)
- Testing
- Implementation of a bundle of care
- Where
- Spain
- Volunteers
- 32,205 people
- Sponsor
- Hospital de Granollers
Peritonitis, Surgical Site Infection
NPWT vs Primary Closure in SSI Prevention for Emergency Laparotomies for Peritonitis
The study aims to evaluate the efficacy of negative pressure wound therapy (NPWT) compared with primary closure (PC) in surgical site infection (SSI) prevention for laparotomy for peritonitis.
- Conditions
- Peritonitis, Surgical Site Infection, Infections, Wound Infection
- Trial name
- PRISTINE (NCT05684198)
- Testing
- subcutaneous NPWT
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Gdansk
Deep Surgical Site Infection, Spine Surgery
Risk Factors Associated With Infection After Spine Surgery
Surgical site infection (SSI), particularly deep SSI, is one of the most serious complications after spinal surgery. evaluating the risk of SSI and, correspondingly, prescription of prophylactic measures are extremely important…
- Trial name
- NCT05740865
- Testing
- open posterior instrumented thoracolumbar surgery
- Where
- China
- Volunteers
- 3,419 people
- Sponsor
- Xuanwu Hospital, Beijing
Hernia Inguinal
A Comparative Study Between TAPP and Lichtenstein Techniques for Inguinal Hernia Surgery
This study is comperative study between TAPP And Lichtenstein Techniques for Inguinal Hernia surgery.The Lichtenstein tension-free open hernioplasty involves placing a tailored polypropylene mesh over the inguinal canal defect…
- Trial name
- NCT07067281
- Testing
- Lichtenstein Tension-Free Mesh Hernioplasty, Laparoscopic Transabdominal Preperitoneal (TAPP) Repair
- Where
- India
- Volunteers
- 60 people
- Sponsor
- GSVM Medical College
Appendicitis
Single-incision Laparoscopic (SILS) Versus Conventional Laparoscopic Appendectomy for the Treatment of Acute Appendicitis
Recent advances in laparoscopic instrumentation have made it possible to perform intra-abdominal operations entirely through a small incision that can be hidden within the umbilicus.
- Trial name
- NCT00997516
- Testing
- SILS appendectomy, conventional laparoscopic appendectomy
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of California, San Francisco
Orthopedic Devices Associated With Misadventures, Infection, Surgical Site
Short Against Long Antibiotic Therapy for Infected Orthopedic Sites
The investigators will perform two concomitant RCTs, depending on the presence of infected osteosynthesis material at enrolment: SALATIO 1. Infected implant not removed (or new material inserted): Randomization 6 vs.
- Conditions
- Orthopedic Devices Associated With Misadventures, Infection, Surgical Site, Antibiotic Side Effect
- Trial name
- SALATIO (NCT05499481)
- Testing
- Antibiotic
- Where
- Switzerland
- Volunteers
- 495 people
- Sponsor
- Balgrist University Hospital
Surgical Site Infection Prevention, Episiotomy Infection
Effect of Topical Diltiazem Plus Fusidic Acid Versus Fusidic Acid Alone on Episiotomy Healing, Pain, and Resumption of Sexual Activity: A Randomized Controlled Trial in Azadi Teaching Hospital
The goal of this clinical trial is to learn if diltiazem gel combined with fucidic acid cream works better than fucidic acid cream alone to prevent surgical site infection following episiotomy repair.
- Conditions
- Surgical Site Infection Prevention, Episiotomy Infection, Episiotomy Wound, Normal Vaginal Delivery
- Trial name
- NCT07545187
- Testing
- Group 1 received sequential topical diltiazem gel 2% followed by fusidic acid cream, and Group 2 received topical fusidic acid cream alone
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Alaa Nadhim Hameed
Cardiac Surgery in Adult Patient
Randomized Trial of 2% Chlorhexidine-70% Isopropanol vs 5% Povidone Iodine-69% Ethanol for Skin Antisepsis in Reducing Surgical-site Infection After Cardiac Surgery
Despite completion of more than 9 million procedures each year in France, the best antiseptic solution to be used for preparing the skin to reduce risk of surgical site infection (SSI) remains unknown.
- Trial name
- CLEAN2 (NCT03560193)
- Testing
- 2%Chlorhexidine-70%Isopropanol, 5%Povidone Iodine- 69%Ethanol
- Where
- 8 sites in France
- Volunteers
- 3,316 people
- Sponsor
- Poitiers University Hospital
Disorder of Hip Region
A Ten-state Cluster-randomized Controlled Trial of the Institute for Health Improvement's Project JOINTS
In 2011, IHI designed a new campaign to accelerate uptake of evidence-based practices that had been shown to prevent surgical site infections (SSI) associated with hip and knee arthroplasty.
- Trial name
- NCT02886741
- Testing
- Quality Improvement Campaign
- Volunteers
- 549 people
- Sponsor
- RAND
Cesarean Wound Disruption, Cesarean Section; Infection
Delayed Primary Closure of Skin in Emergency Caesarean Section
Pregnant mothers requiring emergency cs with history of ruptured membranes would be allocated randomly into two groups in an aim to study the comparative outcome of different methods of skin closure namely primary and delayed…
- Trial name
- NCT04587960
- Testing
- Delayed primary closure of skin incision in Caesarean section in experimental group, Primary closure of skin incision in Caesarean section in active comparator group
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Dr.Jhuma Biswas