Clinical trials: Incisional Hernia Repair
Gastro Esophageal Reflux
GERD Treatment With Transoral Incisionless Fundoplication (TIF) Following Hiatal Hernia Surgery
The investigators prospectively studied ninety nine GERD patients following laparoscopic hiatal surgery combined with transoral incisionless fundoplication at two community hospitals.
- Trial name
- GERD (NCT03143608)
- Testing
- Esophyx
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Peter G Mavrelis
Hernia, Ventral, Hernia Incisional
Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh
This study compares short term outcomes of patients undergoing a hernia repair with heavy weight mesh vs medium weight mesh in clean-contaminated and contaminated cases.
- Trial name
- NCT06409091
- Testing
- Medium weight or Heavy weight mesh
- Where
- United States
- Volunteers
- 1,496 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Incisional Hernia of Midline of Abdomen
Midline Restoration After HYbriD Hernia RepAir Surgery (HYDRA)
The goal of this observational study is to learn about the functioning of the abdominal wall in patients who underwent hybrid (open- and laparoscopic) incisional hernia repair.
- Trial name
- HYDRA (NCT06286124)
- Testing
- Hybrid Surgery
- Where
- Netherlands
- Volunteers
- 52 people
- Sponsor
- Erasmus Medical Center
Incisional Hernia of Midline of Abdomen
RCT Ventralex vs Onlay Mesh in Incisional Hernias
A radomised controlled trial comparing Ventralex patch and Progrip mesh in surgery for midline incisional hernias
- Trial name
- VPatchIncRCT (NCT04358159)
- Testing
- Ventralex, Progrip
- Where
- 2 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Incisional Hernia
Impact Evaluation of Incisional Hernia on Muscular and Postural Function
Purpose of study is to assess perioperative functional parameters of the anterior abdominal wall muscles and postural control status in patients with large and giant incisional hernias in a controlled diagnostic study.
- Trial name
- IHMPF-1 (NCT05990647)
- Testing
- Dynamometric tension assessment, Postural balance, Assessment of the hernia defect size
- Where
- Uzbekistan
- Volunteers
- 95 people
- Sponsor
- Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov
Incisional Hernia Repair
Prospective Evaluation of Laparoscopic and Open Incisional Hernia Repair: a Multicenter Cohort Study
Nowadays incisional hernia are primarily repaired using prosthetic meshes. In Switzerland such meshes are mainly implanted via open or laparoscopic approach.
- Trial name
- IHR_SALTC (NCT01280370)
- Testing
- Abdominal surgery
- Where
- Switzerland
- Volunteers
- 371 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Postoperative Hernia
Prophylaxis of Surgical Wound Infection in Incisional Hernia Repair With Topical Antibiotics (PROTOP-PAR)
Surgical site infection (SSI) is the main complication of surgery. The prevention of superficial SSI by topical prophylaxis is controversial.
- Trial name
- (PROTOP-PAR) (NCT05508152)
- Testing
- Wound irrigation with amoxicillin-clavulanate in saline solution, Wound irrigation with a saline solution
- Where
- Spain
- Volunteers
- 260 people
- Sponsor
- Hospital de Granollers
Incisional Hernia
Risk Factors for Morbidity After Incisional Hernia Repairs
The Danish Ventral Hernia Database (DVHD) registers 37 different perioperative parameters. The aim of present study is to use large-scale data from DVHD to uncover risk factors for readmission, reoperation (any indication), death…
- Trial name
- NCT01430676
- Testing
- differences in surgical techniques
- Where
- Denmark
- Volunteers
- 3,460 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Ventral Hernia, Incisional Hernia
Titanium vs Absorbable Tacks for Mesh Fixation in Laparoscopic Incisional and Ventral Hernia Repair
Background: Laparoscopic repair of ventral hernias has gained popularity, since many studies and a recent meta-analysis have reported encouraging results and recurrence rates similar to open repair.
- Trial name
- NCT02076984
- Testing
- Laparoscopic incisional or ventral hernia repair
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Roma La Sapienza
Incisional Hernia
COMplete Versus PArtial Open inCisional Hernia Repair (COMPAC-TRIAL)
To compare the complete repair of the abdominal wall at the level of the former incision with only a partial repair at the level of the hernia in patients with an incisional hernia after median laparotomy in a prospective…
- Trial name
- COMPAC (NCT00498810)
- Testing
- complete repair, partial repair of the abdominal wall
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- University Hospital, Ghent
Incisional Hernia
Does Preoperative Physical Activity Predict Postoperative Complications After Incisional Hernia Repair ?
Patients with abdominal wall incisional hernia often have numerous comorbidities, making management complex. To date, no study has described the relationship between preoperative physical activity and the occurrence of…
- Trial name
- EVENTEST (NCT07192978)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Postoperative Pain, Complications
Laparoscopic Versus Open Incisional Hernia Repair
Primary closure of incisional hernia without the use of a mesh shows recurrence rates of up to 54%. If a mesh is used, the defect can be closed tension-free. Using this method, recurrence rates have been reduced to 8-21%.
- Conditions
- Postoperative Pain, Complications, Recurrence
- Trial name
- COLIBRI (NCT01420757)
- Testing
- incisional hernia repair
- Volunteers
- 206 people
- Sponsor
- Erasmus Medical Center
Hernia, Ventral, Hernia Incisional
Transversus Abdominis Muscle Release Versus Mesh Only Repair in the Treatment of Complex Ventral Wall Hernia
This trial was designed as a prospective randomized, controlled, intervention, with two parallel groups, and a primary endpoint of recurrence during 12 months' follow-up after initial treatment, with the randomization, was…
- Conditions
- Hernia, Ventral, Hernia Incisional, Hernia, Abdominal
- Trial name
- NCT04516031
- Testing
- Posterior Component Separation with Transversus Abdominis Muscle Release, Mesh-only repair
- Where
- Egypt
- Volunteers
- 59 people
- Sponsor
- Mansoura University
Incisional Hernia, Recurrent Hernia
A Retrospective Analysis of Incisional Hernia Repair's Postoperative Recurrence
ABSTRACT Purpose：A retrospective study was conducted among patients with incisional hernia in our hospital to analyse the factors associated with postoperative recurrence of abdominal wall incisional hernia.
- Trial name
- NCT06102551
- Testing
- Recurrence after surgery
- Where
- China
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Fudan University
Inguinal Hernia
Plasma Total Antioxidant Status and Thiobarbituric Acid-reacting Substances in Patients With Inguinal Hernia
Introduction: Any form of trauma, including surgery is known to result in oxidative stress. Single incision laparoscopy is a step forward towards almost scarless surgery.
- Trial name
- NCT02336256
- Testing
- Procedures of hernia repair.
- Volunteers
- 34 people
- Sponsor
- Poznan University of Medical Sciences
Hernia, Ventral
A Study to Compare Ventral Incisional Hernia by Laparoscopic vs Open Repair With Mesh
The purpose of this research is to compare open ventral incisional hernia repair to the laparoscopic repair with respect to complications, recurrence, pain, return to normal activities of daily living, and return to work.
- Trial name
- NCT00240188
- Testing
- Open mesh repair of ventral incisional hernia, Laparoscopic mesh repair of ventral incisional hernia
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- US Department of Veterans Affairs
Incisional Hernia, Abdominal Hernia
Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair
This trial asks whether covering the inner, bowel-facing surface of a hernia mesh with a flap of the patient's own hernia sac improves healing after repair of a complex ventral (abdominal wall) hernia in which one edge of the…
- Conditions
- Incisional Hernia, Abdominal Hernia, Complex Ventral Hernia, Surgical Site Infection
- Trial name
- PERI-SAC (NCT07720154)
- Testing
- Sac-flap peritonealization of the mesh, Retromuscular (sublay) synthetic mesh repair
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Minia University