Clinical trials: Incisional Pain, open to volunteers
Chronic Pain, Wound Dehiscence
Comparing Polyglactin vs Polypropylene Sutures for Rectus Sheath Closure
This randomized controlled trial aims to compare the outcomes of Polyglactin (Vicryl) versus Polypropylene (Prolene) sutures for rectus sheath closure in patients undergoing midline laparotomy.
- Conditions
- Chronic Pain, Wound Dehiscence, Surgical Site Infection (SSI), Incisional Hernia
- Trial name
- PolySuture (NCT07280975)
- Testing
- Polyglactin 910 (Vicryl) Suture, Polypropylene (Prolene) Suture
- Where
- Pakistan
- Volunteers
- 156 people
- Sponsor
- Lady Reading Hospital, Pakistan
Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection
Pre-incisional Infiltration With Ropivacaine Plus Diprospan for Relieving Postoperative Pain After Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy, but it is still reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection, Segmentectomy, Lobectomy
- Trial name
- NCT07626489
- Testing
- Pre-incisional infiltration with ropivacaine plus diprospan
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Beijing Tiantan Hospital
Apical Periodontitis, Endodontically Treated Teeth
Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery
The purpose of this study is to evaluate the effect of Photobiomodulation (PBM) in postoperative pain after endodontic microsurgery (EMS) in patients from the University of Texas Health Science Center at Houston, School of…
- Conditions
- Apical Periodontitis, Endodontically Treated Teeth, Endodontic Disease, Apical Cyst
- Trial name
- NCT06574152
- Testing
- PBM treatment, EMS
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- The University of Texas Health Science Center, Houston
Loxoprofen Sodium Patch, Local Incision
The Efficacy and Safety of Loxoprofen Sodium Patch in Relieving Postoperative Pain After Laparoscopic Surgery
Studies have shown that up to 80% of patients experience postoperative pain following laparoscopic surgery due to inflammation caused by surgical incisions and surrounding tissues, necessitating pharmacological relief.
- Conditions
- Loxoprofen Sodium Patch, Local Incision, Laparoscopic Cholecystectomy, Appendectomy, Laparoscopic
- Trial name
- NCT07591207
- Testing
- Loxoprofen Sodium Patch on the contralateral side, Loxoprofen Sodium Patch on the incision site
- Where
- 2 sites in China
- Volunteers
- 134 people
- Sponsor
- Beijing Tiantan Hospital
Wound Complication, Surgical Wound Infection
Cosmetic Outcome of Electrocautery, Scalpel and PEAK PlasmaBlade for Surgical Breast Incisions
This study will compare the cosmetic scar result from the use of scalpel, electrocautery, and pulsed electron avalanche knife (PEAK) PlasmaBlade (PPB) for the initial skin incision for total mastectomy procedures without…
- Conditions
- Wound Complication, Surgical Wound Infection, Post-operative Pain, Postoperative Complications
- Trial name
- SCPPB (NCT06191159)
- Testing
- Scalpel and standard electrocautery or PEAK PlasmaBlade, PEAK PlasmaBlade, Standard Electrocautery
- Where
- Canada
- Volunteers
- 186 people
- Sponsor
- University of British Columbia
Post-operative Pain, Cesarean Section
Post-operative Cesarean Trial of Pain Control
This study plans to learn more about postoperative pain management after cesarean deliveries (C-sections). As a part of standard of care, the Children's Hospital Colorado's Colorado Fetal Care Center (CFCC) follows the standard…
- Trial name
- NCT05131178
- Testing
- ON-Q Pump® with continuous infusion of bupivacaine, ON-Q Pump® with continuous infusion of saline
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver
Pain Management, Spine Surgery
Minimum Effective Dose of Incisional Local Infiltration Betamethasone for the Prevention of Pain After Spinal Surgery
Incisional pain is a common complication after surgery and is an important cause of delayed postoperative recovery, increased length of hospital stay, increased risk of wound infection and respiratory/cardiovascular…
- Trial name
- NCT06785350
- Testing
- 0.012%diprospan+0.5%ropivacaine, 0.009%diprospan+0.5%ropivacaine, 0.006%diprospan+0.5ropivacaine
- Where
- China
- Volunteers
- 535 people
- Sponsor
- Beijing Tiantan Hospital
Pain; Cancer, Hepatectomy
Ultrasound Guided External Oblique Intercostal Plane Block Versus Erector Spinae Block for Post Hepatectomy Pain
Management of acute post-operative pain has received keen attention in recent years with considerable concurrent advancement in the field.
- Conditions
- Pain; Cancer, Hepatectomy, Nerve Block
- Trial name
- NCT07337330
- Testing
- Ultrasound guided external oblique intercostal (EOI) plane block, Ultrasound guided erector spinae block
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- National Cancer Institute, Egypt
Impacted Mandibular Third Molar
Comparison of Electrocautery and Scalpel Blade Incisions of Impacted Mandibular Third Molars
This randomized controlled trial aims to compare electrocautery and scalpel blade incisions during surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07723326
- Testing
- scalpel blade incision, electrocautery incision
- Where
- Pakistan
- Volunteers
- 78 people
- Sponsor
- Riphah International University
Postoperative Pain, Postsurgical Pain
Sustained Release Lidocaine for the Treatment of Postoperative Pain
In this study, the investigators are testing a new formulation of lidocaine for its suitability in managing postoperative pain after pelvic (circumcision, inguinal, scrotal), perineal (hemorrhoidectomy) or perianal (fistulotomy)…
- Trial name
- NCT05193227
- Testing
- ST-01, Control (Lidocaine Hydrochloride Injection USP Xylocaine® or Bupivacaine Hydrochloride Injection USP Marcaine®)
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University of British Columbia
Hernia Incisional, Exercise
Impact of Core Muscle Training on Incisional Hernia and Pain After Abdominal Surgery
The current practice to avoid incisional hernia, one of the most frequent complications following abdominal surgery, is to minimize core muscle activity in the postoperative phase.
- Trial name
- NCT03808584
- Testing
- Physiotherapy
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 588 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cystectomy, Myomectomy
Lidocaine for LESS Postoperative Shoulder Pain Alleviation
Objective: To evaluate the efficacy of subdiaphragmatic spray of 0.08% lidocaine in relieving postoperative acute pain and psychological status of patients undergoing single-port laparoscopic surgery for benign gynecological…
- Trial name
- NCT07537127
- Testing
- subdiaphragmatic lidocaine sprayed, standard ERAS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Laparoscopic Surgery, Laparoscopic Appendectomy
Pre-incisional Infiltration With Ropivacaine Plus Diprospan for Relieving Postoperative Pain After Laparoscopic Surgery
Incisional infiltration is the simplest, safest, and most effective anesthesia method for preventing incision pain after laparoscopic surgery, but even using long-acting local anesthetics, the effectiveness of postoperative…
- Conditions
- Laparoscopic Surgery, Laparoscopic Appendectomy, Laparoscopic Cholecystectomy, Laparoscopic Hernia Repair Surgery
- Trial name
- NCT07626463
- Testing
- Pre-incisional infiltration with ropivacaine and diprospan, Pre-incisional infiltration with ropivacaine alone
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Tiantan Hospital
Hemorrhoid Surgery, Liposome Bupivacaine
The Efficacy and Safety of Liposomal Bupivacaine in Relieving Postoperative Pain After Hemorrhoid Surgery
Hemorrhoids represents the most prevalent condition among anorectal disorders. Due to the unique anatomical characteristics of the perianal region, patients frequently experience severe postoperative pain, which may lead some…
- Conditions
- Hemorrhoid Surgery, Liposome Bupivacaine, Pain Management, Local Infiltration
- Trial name
- NCT07442539
- Testing
- Bupivacaine hydrochloride, Liposomal bupivacaine plus bupivacaine
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Beijing Tiantan Hospital
Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection
Pre-incisional Infiltration With Ropivacaine Plus Triamcinolone for Relieving Postoperative Pain After Thoracoscopic Surgery
Video-assisted thoracoscopic surgery (VATS) is less invasive compared to traditional thoracotomy, but it is still reported that the incidence of acute pain following VATS exceeds 80%.
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Wedge Resection, Segmentectomy, Lobectomy of the Lungs
- Trial name
- NCT07603921
- Testing
- Pre-incisional infiltration with ropivacaine plus triamcinolone, Pre-incisional infiltration with ropivacaine alone
- Where
- China
- Volunteers
- 346 people
- Sponsor
- Beijing Tiantan Hospital
Child
The Effect of Supporting the Incision Site With Toys During Mobilization in Children Aged 4-10 Years Undergoing Abdominal Surgery
Aim: The aim of this study is to determine the effect of supporting the wound area with a toy during mobilization on pain and fear in children undergoing abdominal surgery. Method: The study was a randomised controlled trial.
- Trial name
- NCT07428421
- Testing
- Toy Group
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Ventral Hernia, Ventral Incisional Hernia
The IMPACT Study: Personalized Physical Therapy for Better Recovery and a Stronger Core After Hernia Surgery
Ventral hernia repair is among the most common operations performed in the United States each year, yet the great majority of patients receive no structured rehabilitation for the persistent pain, weakness, and functional loss…
- Conditions
- Ventral Hernia, Ventral Incisional Hernia, Post Operative Pain
- Trial name
- IMPACT (NCT07145099)
- Testing
- PT Group, Usual Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Thomas Jefferson University
Pain Management, Hysterectomy
Comparison of Sensory Block Coverage and Clinical Effectiveness of TAP and Rectus Sheath Blocks in Pfannenstiel Incisions
Hysterectomy is one of the most common major gynecologic surgeries performed for various indications, and hundreds of thousands of procedures are carried out annually, particularly in developed countries.
- Trial name
- NCT07260396
- Testing
- Group Transversus Abdominis Plane Block, Group Rectus Sheath Block
- Volunteers
- 30 people
- Sponsor
- Samsun University
Chemical Rectus Sheath Block, Chronic Pain
Ultrasound Guided- Chemical Rectus Sheath Block for Chronic Pain After Abdominal Midline Incision in Cancer Surgeries
The aim of this study is to evaluate peri-operative analgesia efficacy of ultrasound guided transversalis fascia plane block in cancer patients undergoing inguinal lymph node dissection
- Conditions
- Chemical Rectus Sheath Block, Chronic Pain, Abdominal Midline Incision, Cancer Surgeries
- Trial name
- NCT07855380
- Testing
- Saline 0.9%, Transversalis fascia plane block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Paresthesia, Total Hip Arthroplasty (THA)
Percussive vs. Gentle Massage for Recovery After Hip Replacement
Many people who have hip replacement surgery through a "bikini incision" on the front of the hip (anterior approach) develop numbness, tingling, burning, or tightness in the front and side of the thigh afterward.
- Conditions
- Paresthesia, Total Hip Arthroplasty (THA), Direct Anterior Total Hip Arthroplasty, Lateral Femoral Cutaneous Nerve Injury
- Trial name
- NCT07790705
- Testing
- Percussive Massage Therapy (Toloco or Hyperice Hypervolt GO 2), Gentle Manual Massage
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Zachary M Ricciardelli