Clinical trials: Incontinence, Urinary
Vaginal Atrophy
A Clinical Clinical Observation of CO2 Fractional Laser in Female Vaginal Repair
1. Vaginal atrophy is the most common indication in the treatment of vaginal rejuvenation. Its main manifestation is vaginal relaxation syndrome, which may be the early symptom of female pelvic floor dysfunction.
- Trial name
- NCT04492176
- Testing
- CO2 fractional laser（ACUPULSE,Lumenis）
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Urinary Stress Incontinence
Hypertonic Saline Injection For Urinary Incontinence
The investigators aimed to evaluate the effectiveness and safety of periurethral hypertonic saline (10% NaCl) injection for the treatment of stress urinary incontinence (SUI) and stress-predominant mixed urinary incontinence…
- Trial name
- NCT04812574
- Testing
- Periurethral injection, Hypertonic (10%) saline
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Turgut Ozal University
Incontinence, Urinary, Enuresis, Nocturnal
Alarm Treatment for Combined Enuresis and Daytime Urinary Incontinence in Children
The aim is to examine whether alarm therapy in addition to urotherapy can have a beneficial effect in treating urinary incontinence children with combined daytime incontinence and enuresis.
- Conditions
- Incontinence, Urinary, Enuresis, Nocturnal, Enuresis
- Trial name
- ABDE (NCT04260646)
- Testing
- Enuresis Alarm Rodger and Timer watch (Rodger), Timer watch (Rodger)
- Where
- 4 sites in Denmark
- Volunteers
- 89 people
- Sponsor
- Aalborg University Hospital
Urinary Incontinence in Old Age, Fecal Incontinence in Old Age
Tailoring Online Continence Promotion
This project seeks to understand whether, and how, tailoring an online continence intervention can increase engagement and uptake of health behaviors known to improve bladder and bowel symptoms.
- Trial name
- TOCP (NCT05183217)
- Testing
- Online Continence promotion program without tailoring, Online Continence promotion program with tailoring
- Where
- United States
- Volunteers
- 445 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Stress Urinary Incontinence
Vesair Balloon Confirmatory Trial (VECTOR)
Multicenter, prospective, single-arm study to assess the safety and efficacy of the Vesair Bladder Control treatment in post-menopausal women with Stress Urinary Incontinence (SUI) with follow-up at 1, 3 and 12 months.
- Trial name
- VECTOR (NCT03794206)
- Testing
- Vesair Balloon
- Where
- 8 sites in United States
- Volunteers
- 20 people
- Sponsor
- Solace Therapeutics, Inc.
Electrical Stimulation
Electrical Stimulation in Men With Urinary Incontinence After Radical Prostatectomy
Aim: In this study, the investigators aimed to assess the efficacy of perineal electrical stimulation on anxiety, depression, quality of life (QOL), and clinical parameters associated with incontinence in men with urinary…
- Trial name
- NCT05236140
- Testing
- Perineal electrical stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Pamukkale University
Urinary Incontinence
Muscle Progenitor Cell Therapy for Urinary Incontinence
This study is designed to evaluate the safety of muscle progenitor cells (MPCs) for the treatment of urinary incontinence due to incompetent outlet (bladder neck/urethra).
- Trial name
- MPC (NCT01953315)
- Testing
- Autologous Muscle Progenitor Cells
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University
Overactive Bladder, Urinary Incontinence, Urge
Efficacy of Li-SWT on Persistent Storage Symptoms After Transurethral Surgery for BPO
comparing the outcome of low-intensity shock wave therapy (Li-SWT) versus solifenacin on persistent storage symptoms after transurethral surgery for benign prostatic obstruction (BPO)
- Conditions
- Overactive Bladder, Urinary Incontinence, Urge, Urgency-frequency Syndrome, Post Prostatectomy
- Trial name
- NCT04437108
- Testing
- Li-SWT (suprapubic approach), Li-SWT (perineal approach), Li-SWT (combined approach)
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Mansoura University
Overactive Bladder, Pelvic Organ Prolapse
The Effect of an Additional Stress Incontinence Procedure on Overactive Bladder During Pelvic Organ Prolapse Repair
Pelvic organ prolapse (POP) is a common condition in women. Approximately 20% of women undergo surgical correction for POP in their lifetime.
- Trial name
- NCT02502838
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Pelvic Organ Prolapse, Urinary Incontinence
Intelligent Diagnosis and Treatment System for Pelvic Floor Dysfunction in Elderly Women
The aim of this study is to propose an intelligent diagnosis and treatment system for for pelvic floor dysfunction in elderly women.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Diagnosis
- Trial name
- NCT06372340
- Testing
- Personalized pelvic floor rehabilitation program generated by the intelligent diagnosis and treatment system., Standard pelvic floor muscle training(PFMT) program
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Hospital
Overactive Bladder, Urge Incontinence
Effects of Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in Adults
For overactive bladder symptoms, there are numerous physiotherapy techniques have been found to be beneficial. Transcutaneous electrical stimulation of the tibial nerve is one of those treatment options, that is entirely a…
- Conditions
- Overactive Bladder, Urge Incontinence, Nocturia
- Trial name
- NCT05464589
- Testing
- Transcutaneous tibial nerve stimulation along with pelvic floor muscle srengthening, Pelvic floor muscles strengthening
- Where
- 3 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Urinary Incontinence
Comparison of Body and Room Temperature Saline in Urodynamics
The purpose of this study is to compare first urge, strong urge, and maximum capacity, and perception of discomfort during urodynamic testing between room temperature and body temperate saline.
- Trial name
- NCT00355433
- Testing
- Urodymanics
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tripler Army Medical Center
Cystocele, Stress Urinary Incontinence
Anterior Defect Correction With Mesh Plus Treatment of Stress Incontinence With Transobturator or Transvaginal Approach
The incidence of anterior pelvic defect in women is estimated about 10% and it may be often associated to urinary stress incontinence.
- Trial name
- NCT00743535
- Testing
- Transobturatory correction of anterior defect plus TOT, Transobturatory correction of anterior defect plus TVT
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University Magna Graecia
Urinary Incontinence
Effectiveness of PeeRelease - a Gel Absorbent Pad in Moderate to Severe Urinary Incontinence
The purpose of the proposed study is to test the effect of the new gel pad on the quality of life of urinary incontinent men and women and to assess to what extent the gel pad improves the quality of life of incontinence persons.
- Trial name
- NCT01066117
- Testing
- PeeRelease gel absorbent pad
- Where
- Israel
- Volunteers
- 90 people
- Sponsor
- Tisteron Ltd.
Pelvic Organ Prolapse, Stress Urinary Incontinence
Lidocaine for Pessary Check Pain Reduction
The primary objective of this study is to estimate the effect of lidocaine jelly on patient pain at the time of office pessary removal.
- Trial name
- NCT05493735
- Testing
- Lidocaine Hcl 2% Jelly
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Urinary Incontinence, Stress
Predictive Role of Urodynamics on Mid-urethral Sling Failure
Purpose The aim of this study is to investigate the contribution of preoperative urodynamics to mid-urethral slings (MUS) success for developing an algorithm that uses conventional and easily accessible tools Methods Women with…
- Trial name
- UPMUSF (NCT02337374)
- Testing
- Midurethral sling mesh
- Volunteers
- 242 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Postpartum Urinary Incontinence
Pelvic Floor Rehabilitation Study (Beckenboden-Rehabilitationsstudie - BREST)
This study compares the effectiveness of standard care, pelvic floor muscle training or vaginal pessary for the treatment of postpartum urinary incontinence.
- Trial name
- NCT06031870
- Testing
- Vaginal pessary, Standard care, Pelvic floor muscle training
- Where
- 4 sites in Germany
- Volunteers
- 52 people
- Sponsor
- Medical University of Vienna
Urinary Incontinence,Stress, Urinary Incontinence
Platelet-Rich Plasma for Stress Urinary Incontinence
The aim of this randomized controlled trial study is to evaluate the efficacy and safety of platelet-rich plasma (PRP) in the treatment of female stress urinary incontinence (SUI), compared to placebo.
- Trial name
- NCT05390970
- Testing
- Platelet-rich plasma injection
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Annah J. Vollstedt
Overactive Bladder Syndrome
A 12-Week Study to Evaluate the Efficacy of Darifenacin to Increase the Warning Time in Patients With Overactive Bladder.
This study will assess the efficacy of a 12-week treatment with darifenacin in increasing warning time, the time from first sensation of urgency to voiding, in patients with OAB.
- Trial name
- NCT00171145
- Testing
- Darifenacin
- Where
- United States
- Volunteers
- 445 people
- Sponsor
- Novartis