Clinical trials: Incontinence Stress
Urinary Incontinence, Stress
Autologous Muscle Derived Cells Female Stress Urinary Incontinence Clinical Study
This is a clinical trial to study the safety and effectiveness of Autologous Muscle Derived Cells for Urinary Sphincter Repair (AMDC-USR) for the treatment of female stress urinary incontinence (SUI).
- Trial name
- NCT01382602
- Testing
- AMDC-USR
- Where
- 10 sites in Canada, Germany and 1 more
- Volunteers
- 150 people
- Sponsor
- Cook MyoSite
Urinary Incontinence
Female Patients With Signs of uRgE and Stress Urinary Incontinence Study of Propiverine Hydrochloride
This study is to evaluate the efficacy and safety that the occurrence of incontinence is significantly decrease using the propiverine hydrochloride for 200 female patients with mixed (stress and urge) urinary incontinence in one…
- Trial name
- FRESH (NCT01942681)
- Testing
- Propiverine Hydrochloride
- Where
- Japan
- Volunteers
- 62 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Pelvic Organ Prolapse, Stress Urinary Incontinence
Pessary Experience Study
Pessaries are silicone devices inserted into the vagina for treatment of pelvic organ prolapse or stress urinary incontinence. They are adequate treatment options for patients who are poor surgical candidates, those who decline…
- Trial name
- NCT06021769
- Testing
- Observational only
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Stress Urinary Incontinence, Urinary Incontinence
Efficacy of a Non-invasive Pelvic Floor Muscle Trainer for Treatment of Stress Urinary Incontinence
The goal of this clinical trial is to assess the efficacy and usability of the electromyography component of the company's pelvic health product in a patient population with stress urinary incontinence.
- Conditions
- Stress Urinary Incontinence, Urinary Incontinence, Pelvic Floor Disorders
- Trial name
- NCT05624645
- Testing
- Pelex Upp
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Pelex
Urinary Incontinence
TOMUS-Trial Of Mid-Urethral Slings
The primary aim of this clinical trial is to compare treatment success for two minimally invasive surgical procedures to treat stress urinary incontinence in women. These procedures are called mid-urethral slings.
- Trial name
- TOMUS (NCT00325039)
- Testing
- retropubic mid-urethral sling (TVT), transobturator mid-urethral sling (TVT-O and the Monarc)
- Where
- 11 sites in United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Urinary Incontinence, Urinary Incontinence, Stress
Can Women Correctly Contract Their Pelvic Floor Muscles After to Receive Verbal Instructions and Vaginal Palpation?
The pelvic floor muscle training (PFMT) is a conservative treatment, currently considered as first line for women with stress urinary incontinence (SUI).
- Conditions
- Urinary Incontinence, Urinary Incontinence, Stress, Urination Disorders, Lower Urinary Tract Symptoms
- Trial name
- NCT03325543
- Testing
- Visual observation, Vaginal palpation (bidigital touch)
- Where
- Brazil
- Volunteers
- 176 people
- Sponsor
- Federal University of São Paulo
Stress Urinary Incontinence, Intrinsic Sphincter Deficiency
Local Anesthesia Before Bulkamid Injection
While recommended pre-anesthesia for polyacylamide hydrogel (PAHG, Bulkamid) injections for stress urinary incontinence and intrinsic sphincter deficiency can include intraurethral anesthetic gel with or without periurethral…
- Trial name
- LAB (NCT06043063)
- Testing
- Topical lidocaine, EMLA cream, Periurethral block
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Medstar Health Research Institute
Lower Urinary Tract Symptom in Severe Cystocele Women
Prevalence Rates of USI, BO, DO and Their Clinical and Urodynamic Findings in Women With ≥Stage II Cystocele
Prevalence rates of urodynamic stress incontinence (USI), bladder oversensitivity (BO) /detrusor overactivity (DO) or both and their related clinical and urodynamic findings in women with ≥ pelvic organ prolapse quantification…
- Trial name
- NCT03613350
- Testing
- Pad test
- Volunteers
- 480 people
- Sponsor
- National Taiwan University Hospital
Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI)
Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery
Suzetrigine is a selective NaV1.8 inhibitor that provides peripheral analgesia without opioid-related CNS effects. This single-center stepped-wedge randomized clinical trial evaluates whether a suzetrigine-based postoperative…
- Conditions
- Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI), Postoperative Pain
- Trial name
- NCT07600697
- Testing
- Suzetrigine, Opioid Analgesics (Tramadol or Oxycodone), Scheduled Acetaminophen and Ibuprofen
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Stress Urinary Incontinence
Abdominal-Kegel Exercise and the Effect of Telemedicine in Stress Urinary Incontinence
Urinary incontinence is a very common health problem that reduces the quality of life mostly in women. Behavioral therapy (lifestyle changes, abdominal-Kegel exercises) is recommended as the first choice in the treatment of the…
- Trial name
- NCT06189443
- Testing
- Group administered to individual telemedicine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Urinary Incontinence,Stress, Urinary Incontinence, Urge
RCT on Multimodal Self-treatment for Women With Incontinence Using a Digital Health Application
This study, titled "Prospective Randomized Study on Multimodal Self-Treatment for Women with Incontinence Symptoms Using a Digital Health Application," abbreviated as DINKS, aims to investigate the efficacy of a digital health…
- Conditions
- Urinary Incontinence,Stress, Urinary Incontinence, Urge, Urinary Incontinence, Overactive Bladder Syndrome
- Trial name
- DINKS (NCT06389838)
- Testing
- Kranus Mictera
- Where
- Germany
- Volunteers
- 194 people
- Sponsor
- Kranus Health GmbH
Stress Urinary Incontinence
Importance of Patient Positioning at Cough Test When Considering Success Following Sling Procedures
This is a prospective study to assess the feasibility and success of performing an intra-operative standing cough test and the correlation with the long term success of the sling surgery.
- Trial name
- DISST (NCT03120117)
- Testing
- Cough Test following Sling Surgery
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Michigan Institution of Women's Health PC
Stress Urinary Incontinence
Comparing KIM to TVT Exact Sling
To assess to the non-inferiority of the retropubic Neomedic Knotless Incontinence Mesh (KIM) sling compared to the Gynecare Tension-free Vaginal Tape (TVT) Exact sling.
- Trial name
- NCT04985799
- Testing
- Gynecare TVT Exact Continence System, Neomedic KIM (Knotless Incontinence Mesh)
- Where
- 2 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Stress Urinary Incontinence
PEMF vs Laser for Stress Urinary Incontinence
Stress urinary incontinence, or involuntary urine leakage during activities like coughing, laughing, or exercise, is a common condition that impacts quality of life for many women.
- Trial name
- NCT06137326
- Testing
- Pulsed Electromagnetic Field Therapy, Laser Acupuncture
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ahram Canadian University
Menopause, Urinary Incontinence, Stress
Pelvic Floor Muscle Training With and Without Biofeedback in Women With Stress Urinary Incontinence
This study evaluates the action of the pelvic floor muscle training with and without EMG Biofeddback in the treatment of stress urinary incontinence in menopausal, peri and post menopausal women and their quality of life before…
- Trial name
- NCT02275728
- Testing
- Pelvic floor muscle training, Eletromyography Biofeedback
- Volunteers
- 45 people
- Sponsor
- Federal University of Rio Grande do Sul
Stress Urinary Incontinence, Patient Satisfaction
Postoperative Activity Restrictions After Slings
Postoperative restrictions are often based on expert opinion and "common sense". There is a wide variety in the recommended activity limitation amongst pelvic floor surgeons.
- Conditions
- Stress Urinary Incontinence, Patient Satisfaction, Surgery
- Trial name
- PARS (NCT04552457)
- Testing
- No activity restrictions, Activity restrictions
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Stress Urinary Incontinence
Exploratory Trial of TAS-303 in Female Patients With Stress Urinary Incontinence
The purpose of this study is to evaluate the efficacy and safety of TAS-303 in female patients with stress urinary incontinence.
- Trial name
- NCT02906683
- Testing
- TAS-303
- Where
- Japan
- Volunteers
- 337 people
- Sponsor
- Taiho Pharmaceutical Co., Ltd.
Urinary Incontinence, Radical Prostatectomy
Mechanical Nerve Stimulation in the Treatment of Post Prostatectomy Incontinence
During transcutaneous mechanical nerve stimulation in spinal cord injured men an increase in pressure was observed in the external urethral sphincter along with an increase in bladder capacity.
- Trial name
- NCT01540656
- Testing
- Transcutaneous mechanical nerve stimulation (TMNS) (FERTI CARE)
- Where
- 2 sites in Denmark
- Volunteers
- 39 people
- Sponsor
- Copenhagen University Hospital at Herlev
Genital Prolapse
Mechanism of Incontinence Before and After Genital Prolapse Surgery
Since year 2003, Glostrup/Herlev Hospital has devised a novel technique, urethral pressure reflectometry (UPR), for measurements of pressure and cross-sectional area in the female urethra.
- Trial name
- NCT02050568
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Herlev Hospital
Stress Urinary Incontinence
Autologous Stem Cells for Urinary Incontinence: Single Patient Compassionate Use
Determine safety and effectiveness of the technique using autologous stem cells in the treatment of urinary incontinence in one male subject.
- Trial name
- NCT01648491
- Testing
- Muscle Biopsy, Injection of autologous stem cells
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Kenneth Peters, MD