Clinical trials: Incontinence Stress
Urinary Incontinence (UI), Laser Therapy
Laser Therapy and Pelvic Floor Muscle Training for Stress Urinary Incontinence
The aim of this study was to investigate the effects of Pelvic Floor Muscle Training (PFMT) in addition to high-intensity laser therapy (HILT) on pelvic floor dysfunction, sexual dysfunction, and quality of life in women with…
- Conditions
- Urinary Incontinence (UI), Laser Therapy, Stress Urinary Incontinence (SUI), Pelvic Floor Muscle Exercise
- Trial name
- NCT07319247
- Testing
- PFME and Laser Therapy, Plasebo Laser, PFME
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Necmettin Erbakan University
Stress Urinary Incontinence (SUI)
Long-term Outcomes of Urethral Ligament Plication and Transvaginal Tape Surgery
In the treatment of urinary incontinence caused by coughing, sneezing, or heavy lifting, the investigators will perform urinary tract tightening surgery, both with and without a sling, to address the relaxed urinary tract.
- Trial name
- TVT/ULP (NCT07484321)
- Testing
- Transvaginal tape, Urethral ligament plication
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Sanliurfa Education and Research Hospital
Stress Urinary Incontinence, Urinary Incontinence
A Single-Blind, Randomized Study to Compare fCO2 Laser Therapy Versus Sham for Treatment of SUI in Women
This is a prospective randomized sham-controlled study of patients undergoing vaginal treatment with a fractional carbon dioxide (fCO2) laser for stress urinary incontinence (SUI) symptoms.
- Trial name
- LaserSUI (NCT04253067)
- Testing
- Active fCO2 laser treatment
- Where
- United States
- Sponsor
- Corewell Health East
Urinary Incontinence , Stress, Urinary Incontinence (UI)
Effectiveness of DNS on Incontinence Severity, Pelvic Floor Strength and QoL in Urinary Incontinence
The aim of this study is to investigate the effects of Dynamic Neuromuscular Stabilization (DNS) Training on incontinence severity, pelvic floor muscle strength, and quality of life in women with Urinary Incontinence, compared to…
- Conditions
- Urinary Incontinence , Stress, Urinary Incontinence (UI), Exercise
- Trial name
- NCT06627452
- Testing
- Dynamic Neuromuscular Stabilization Training, Pelvic Floor Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Istanbul University - Cerrahpasa
Urinary Incontinence,Stress, Urinary Incontinence, Urge
RCT on Multimodal Self-treatment for Women With Incontinence Using a Digital Health Application
This study, titled "Prospective Randomized Study on Multimodal Self-Treatment for Women with Incontinence Symptoms Using a Digital Health Application," abbreviated as DINKS, aims to investigate the efficacy of a digital health…
- Conditions
- Urinary Incontinence,Stress, Urinary Incontinence, Urge, Urinary Incontinence, Overactive Bladder Syndrome
- Trial name
- DINKS (NCT06389838)
- Testing
- Kranus Mictera
- Where
- Germany
- Volunteers
- 194 people
- Sponsor
- Kranus Health GmbH
Stress Urinary Incontinence, Kegel's Exercise
Tactile Feedback Pelvic Floor Training to Prevent Stress Urinary Incontinence in the 3rd Trimester of Pregnancy
Pregnancy involves significant physiological changes, such as hormone fluctuations, weight gain, and fetal growth, which can affect multiple organ systems.
- Conditions
- Stress Urinary Incontinence, Kegel's Exercise, Sense of Touch, Physical Symptoms
- Trial name
- NCT07668128
- Testing
- Pelvic floor muscle training, Basic Health Education Group, Tactile pelvic floor muscle training group
- Where
- Taiwan
- Volunteers
- 141 people
- Sponsor
- Far Eastern Memorial Hospital
Stress Urinary Incontinence
Japanese Bridging Study of Autologous Muscle Derived Cells Compared to Placebo for Female Urinary Sphincter Repair(JPN1)
This is a confirmatory/bridging study to evaluate the efficacy and safety of Autologous Muscle Derived Cells for Urinary Sphincter Repair (AMDC-USR) compared with placebo in the treatment of stress urinary incontinence (SUI) in…
- Trial name
- JPN1 (NCT03997318)
- Testing
- AMDC-USR
- Sponsor
- Cook MyoSite
Lower Urinary Tract Symptoms
The Effect of Diuresis During 20-minute Pad Test on the Estimation of the Severity of Stress Urinary Incontinence
The aim of this study is to estimate the amount of extra urine produced by natural diuresis during 20-minute pad test, and assess the effect of diuresis on the accuracy of using 20-minute pad test to estimate the severity of SUI.
- Trial name
- NCT02126618
- Where
- Taiwan
- Volunteers
- 3,000 people
- Sponsor
- National Taiwan University Hospital
Stress Urinary Incontinence
Is the Cough Stress Test Equivalent to the 24 Hour Pad Test in the Assessment of Stress Incontinence?
The purpose of this research study is to identify if the cough stress test is equal to the 24hour pad test in assessing stress urinary incontinence.
- Trial name
- NCT01123096
- Testing
- Cough Stress Test, 24 Hour Pad Test
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Irvine
Mixed Incontinence, Urge and Stress
Mixed Urinary Incontinence Symptoms Before and After Treatment With Botox and Bulkamid
This study compares mixed urinary incontinence symptoms before and after a combined treatment with Botox and Bulkamid. Eligible for the study are adult females with a mixed urinary incontinence, having both urgency urinary…
- Trial name
- NCT02815046
- Testing
- Botulinum toxin type A, Polyacrylamide hydrogel
- Where
- Switzerland
- Volunteers
- 58 people
- Sponsor
- Prof. Dr. Volker Viereck
Stress Urinary Incontinence
Effectiveness and Safety of Cell-Assisted Lipotransfer for the Treatment of Stress Urinary Incontinence
Autologous washed and homogenized fat micrograft harvested from the patient's front abdominal wall enriched with adipose-derived regenerative cells (ADRC) derived by enzyme-treatment of a portion of the harvested fat.
- Trial name
- NCT01850342
- Testing
- Periurethral injection of fat micrograft enriched with ADRC
- Where
- Russia
- Volunteers
- 12 people
- Sponsor
- Burnasyan Federal Medical Biophysical Center
Urinary Incontinence, Urinary Incontinence, Stress
IRIS: Incontinence Research Intervention Study
The IRIS project stands for Incontinence Research Intervention Study. The purpose of this research project is to develop an effective behavioral therapy for urinary incontinence and specifically to test Knack therapy, a self-help…
- Trial name
- NCT00125177
- Testing
- Knack therapy
- Where
- United States
- Volunteers
- 320 people
- Sponsor
- University of Michigan
Stress Urinary Incontinence
Retropubic vs. Transobturator Tension-free Vaginal Tape
The so-called tension-free vaginal tape (TVT), first described in Sweden in 1996, has become a standard operation worldwide for the treatment of women with stress urinary incontinence.
- Trial name
- NCT00441454
- Testing
- Transobturator Tension-free vaginal tape (TVT-O), Retropubic Tension-free vaginal tape (TVT)
- Where
- 4 sites in Austria
- Volunteers
- 564 people
- Sponsor
- Austrian Urogynecology Working Group (AUWG)
Stress Urinary Incontinence
Study to Assess Enobosarm (GTx-024) in Postmenopausal Women With Stress Urinary Incontinence
GTx-024 is an orally bioavailable and tissue-selective nonsteroidal selective androgen receptor modulator (SARM) that has demonstrated androgenic and anabolic activity and is currently being evaluated as a potential treatment for…
- Trial name
- ASTRID (NCT03241342)
- Testing
- GTx 024
- Where
- 62 sites in United States
- Volunteers
- 491 people
- Sponsor
- GTx
Stress Urinary Incontinence
Exploratory Trial of TAS-303 in Female Patients With Stress Urinary Incontinence
The purpose of this study is to evaluate the efficacy and safety of TAS-303 in female patients with stress urinary incontinence.
- Trial name
- NCT02906683
- Testing
- TAS-303
- Where
- Japan
- Volunteers
- 337 people
- Sponsor
- Taiho Pharmaceutical Co., Ltd.
Stress Urinary Incontinence
Electroacupuncture and Pelvic Floor Muscle Training for Male Stress Urinary Incontinence
The goal of this clinical study is to compare the effects of combined electroacupuncture with pelvic floor muscle training (PFMT) versus PFMT alone in the treatment of involuntary urine leakage following prostate removal…
- Trial name
- NCT05773716
- Testing
- Pelvic floor muscle training, Electroacupuncture
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Urinary Incontinence,Stress
Use of Non-ablative Vaginal Erbium YAG Laser for the Treatment of Stress Urinary Incontinence.
This is a single center, investigator initiated study, sponsored by the UZ Leuven, Leuven, Belgium; comparing laser treatment to pelvic floor exercises (PFE).
- Trial name
- VELSUI (NCT04643353)
- Testing
- Non-ablative vaginal Erbium YAG laser treatment, PFE
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Urinary Stress Incontinence
Pelvic Floor Contraction in Different Positions Among Women With and Without Stress Urinary Incontinence
Examination of pelvic floor contraction in different positions among women with and without stress urinary incontinence (SUI) will be conducted via diagnostic ultrasound.
- Trial name
- NCT04288648
- Testing
- ultrasound examination
- Where
- Israel
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Stress Urinary Incontinence, Menopause
The Anabolic Effect of Testosterone on Pelvic Floor Muscles
Stress urinary incontinence is the most common female pelvic floor disorder encountered in clinical practice with significant negative impact on quality of life.
- Trial name
- NCT06111209
- Testing
- Testosterone cypionate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Incontinence, Overactive Bladder, Stress Urinary Incontinence
Investigation of the Suburothelial Myofibroblast Network and of Smooth Muscle Function and Control in the Human Urinary Outflow Tract
The aim is to find out if adreno-muscarinic synergy is present also in human tissues of the urinary outflow tract that have a dual adrenergic-muscarinic receptor fitting.
- Trial name
- NCT01227447
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich