Clinical trials: Incontinence Stress
Female Stress Urinary Incontinence
Safety and Efficacy of Carbone Dioxide (CO2) Laser System in Treatment of Female Stress Urinary Incontinence.
This is a prospective, open-label, multi-center, non-comparative study that will be conducted on female subjects between 30 and 75 years of age, diagnosed with stress urinary incontinence (SUI).
- Trial name
- CO2 (NCT02981654)
- Testing
- Alma Lasers Pixel carbon dioxide laser system
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Urodynamic Stress Incontinence
Tension Free Vaginal Tape (TVT) Versus the Miniarc Sling
The aim of this study is to assess whether the Miniarc suburethral sling is equivalent to the TVT in the treatment of women with urodynamic stress incontinence (USI).
- Trial name
- NCT00843908
- Testing
- Tension Free Vaginal Tape, Miniarc
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- Medway NHS Foundation Trust
Urinary Stress Incontinence, Pain
Effects of Topical Lidocaine During Urodynamic Testing In Women
Urodynamic testing is used to help diagnose causes of urinary incontinence and voiding dysfunction. The purpose of the urodynamic test is to gain insight into the patient's urinary symptoms and assist in making a diagnosis.
- Trial name
- NCT03881293
- Testing
- lidocaine 2% gel, water soluble lubricant
- Volunteers
- 110 people
- Sponsor
- Kristine Zinkgraf
Stress Urinary Incontinence (SUI)
Mesh-Free Versus Mesh-Based Surgery for Female Stress Urinary Incontinence: A Prospective Comparison of Pubo-Urethral Ligament Plication and Transobturator Tape
This prospective clinical study aims to compare the short-term effectiveness, safety, and patient-reported outcomes of two surgical techniques used for the treatment of female stress urinary incontinence (SUI): Pubo-Urethral…
- Trial name
- PLP-TOT (NCT07290114)
- Testing
- Pubo-Urethral Ligament Plication (PLP), Transobturator Tape (TOT)
- Where
- Turkey (Türkiye)
- Volunteers
- 147 people
- Sponsor
- Mehmet Incebıyik
Urinary Incontinence
Female Patients With Signs of uRgE and Stress Urinary Incontinence Study of Propiverine Hydrochloride
This study is to evaluate the efficacy and safety that the occurrence of incontinence is significantly decrease using the propiverine hydrochloride for 200 female patients with mixed (stress and urge) urinary incontinence in one…
- Trial name
- FRESH (NCT01942681)
- Testing
- Propiverine Hydrochloride
- Where
- Japan
- Volunteers
- 62 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Stress Urinary Incontinence
A Comparison of the Retropubic (TVT) With the Transobturator Sling Operation in the Treatment of Female Stress Urinary Incontinence or Stress Dominated Mixed Urinary Incontinence
The midurethral tension-free vaginal tape (a macroporous polypropylene mesh) procedure is a well established technique for treating female stress urinary incontinence in patients with (hyper)mobile urethra.
- Trial name
- NCT00642109
- Testing
- midurethral sling procedure
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- David Scheiner
Genuine Stress Incontinence
Prospective Study of Altis System With the TVTO Procedure for the Management of Stress Urinary Incontinence in Women
Prospective randomized comparison of minisling (altis) with the TVTO procedure for the management of women with genuine stress urinary incontinence.
- Trial name
- NCT03515109
- Testing
- Altis tape, TVTO
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aretaieio Hospital
Pelvic Organ Prolapse
Treatment of Urinary Stress Incontinence During or Following Correction of Pelvic Organ Prolapse
The incidence of pelvic organ prolapse (POP) in parous women is estimated over 50%. A variety of urinary, bowel and sexual symptoms may be associated with POP.
- Trial name
- NCT00697489
- Testing
- correction of POP plus preventive continence procedure, POP surgery followed by eventual incontinence procedure
- Where
- Italy
- Sponsor
- University Magna Graecia
Stress Urinary Incontinence
Observational Registry for Iltamiocel Compared to Placebo for Urinary Sphincter Repair in Post-surgical Female Stress Incontinence
The main purpose of this registry is to collect observational, long-term safety and effectiveness data in subjects who have received at least one dose of iltamiocel as part of the CLBT clinical study.
- Trial name
- CLBT RGST (NCT06743620)
- Testing
- iltamiocel
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Cook MyoSite
Stress Urinary Incontinence
Altis® 522 Trial - Treatment of Female Stress Urinary Incontinence
The aim of this postmarket study is to compare the safety and effectiveness of the Altis Single Incision Sling (SIS) to an FDA cleared transobturator and/or retropubic sling through 36 months.
- Trial name
- NCT02348112
- Testing
- Altis Single Incision Sling, Transobturator or Retropubic Sling
- Where
- 27 sites in United States, Canada
- Volunteers
- 416 people
- Sponsor
- Coloplast A/S
Pelvic Organ Prolapse, Stress Urinary Incontinence
Effect of a Risk Calculator on Patient Satisfaction With the Decision for Midurethral Sling During Prolapse Surgery
Pelvic organ prolapse occurs with descent of one or more pelvic structures: the uterus and/or cervix, bowel, bladder, or rectum.
- Conditions
- Pelvic Organ Prolapse, Stress Urinary Incontinence, Satisfaction
- Trial name
- NCT02111642
- Testing
- Online risk calculator
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Stress Urinary Incontinence
Efficacy of Electroacupuncture (EA) for Women With Pure Stress Urinary Incontinence (SUI)
The purpose of this study is to preliminarily assess the efficacy of electroacupuncture (EA) for women with pure stress urinary incontinence (SUI).
- Trial name
- NCT02445573
- Testing
- EA
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Urinary Incontinence
Mixed Incontinence: Medical Or Surgical Approach?
The purpose of this study is to compare treatment outcomes for patients with mixed urinary incontinence (MUI) for whom therapy is initiated with surgery to those for whom therapy is initiated with non-surgical treatment.
- Trial name
- MIMOSA (NCT00803270)
- Testing
- Non-Surgical Intervention, Surgical
- Where
- 10 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Carelon Research
Stress Urinary Incontinence
Optimized Acupuncture Treatment for Female Stress Urinary Incontinence
This multicenter randomized controlled trial is designed to explore a relatively suitable application of acupoint combinations and to provide certain clinical evidence for the optimization of acupuncture treatment of female SUI.
- Trial name
- NCT05635669
- Testing
- Sacral acupoints acupuncture, Abdominal acupoints acupuncture, Alternating acupoints acupuncture
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Yin Ping
Urinary Incontinence , Stress
Clinical Trial of Autologous Adipose Derived Regenerative Cells for the Treatment of Male Stress Urinary Incontinence
The purpose of this study is to evaluate the efficacy and safety of periurethral injection of autologous Adipose Derived Regenerative Cells (ADRCs) in male stress urinary incontinence.
- Trial name
- ADRESU (NCT02529865)
- Testing
- Periurethral injection of autologous ADRCs and adipose tissue
- Where
- 4 sites in Japan
- Volunteers
- 45 people
- Sponsor
- Nagoya University
Stress Urinary Incontinence
Sexual Fonction and Discomfort in Women After Midurethral Sling Surgery, Using PPSSQ
Evaluation of the sexual quality of life of women who had a sub-urethral sling several years ago, using a recently validated questionnaire: the PPSSQ (Pelvi-Perineal Surgery Sexuality Questionnaire).
- Trial name
- SEXBSU (NCT05527665)
- Testing
- Midurethral sling surgery
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Stress Urinary Incontinence
Efficacy of Mini Sling Versus Transobturator Tape in Surgical Management of Women With Stress Urinary Incontinence
To compare the efficacy of mini sling against Transobturator tape for surgical management of women with stress urinary incontinence.
- Trial name
- NCT06334848
- Testing
- transobturator tape
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Chronic Cough
Efficacy and Safety of Gefapixant (MK-7264) in Women With Chronic Cough and Stress Urinary Incontinence (MK-7264-042)
The purpose of this study is to evaluate the efficacy and safety of gefapixant, in improving symptoms of cough-induced stress urinary incontinence (SUI) in adult female participants with refractory or unexplained chronic cough.
- Trial name
- NCT04193176
- Testing
- Gefapixant
- Where
- 90 sites in United States, Argentina and 10 more
- Volunteers
- 376 people
- Sponsor
- Merck Sharp & Dohme LLC
Incontinence Stress, Incontinence
The Relationship Between Pelvic Floor Muscle Function and Hip Pain Among Women
This study examines the relationship between pelvic floor muscle (PFM) function and self-perception of PFM contraction with hip pain, their severity, and hip muscle strength.
- Conditions
- Incontinence Stress, Incontinence, Hip Pain Chronic
- Trial name
- NCT06470620
- Testing
- pelvic floor muscle assessment
- Where
- Israel
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Urinary Stress Incontinence
Safety and Efficacy Study on the Implantation of the Tension-Free Vaginal Tape (TVT-Secur) Under Local Anesthesia
The objective was to observe the satisfaction of local anesthesia during the implantation of the TVT-SECUR for the treatment of stress urinary incontinence, with the use of questionnaires completed by the patients, and to…
- Trial name
- NCT00904618
- Testing
- TVT-SECUR - 'Hammock' technique, TVT-SECUR - 'U-Method', Local anesthesia (30 to 40 ml of a mixture of 35 ml of lidocaine 2% and 5 ml of bicarbonate 3%).
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Université de Sherbrooke