Clinical trials: Incretins
Type 2 Diabetes Mellitus, Heart Failure
SGLT2i and Incretin and CRTd.
Incretin therapy and sodium-glucose- transporter2 inhibitors (SGLT2i) are a treatment for type 2 diabetes (T2DM) affected by heart failure (HF) and treated with cardiac resynchromization therapy (CRT).
- Trial name
- NCT03282136
- Testing
- Incretin Effect, Cardiac Resynchronization therapy defibrillator device, SGLT-2 inhibitor
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Campania Luigi Vanvitelli
Type 2 Diabetes
Liraglutide Hospital Discharge Trial
High blood glucose levels in hospitalized patients with diabetes are associated with increased risk of medical complications and death.
- Trial name
- NCT01919489
- Testing
- Liraglutide + OADs, Glargine + OADs
- Where
- 5 sites in United States
- Volunteers
- 273 people
- Sponsor
- Emory University
Pancreas-kidney Transplantation, Kidney Transplantation
Bile Acids and Incretins in Pancreas Kidney Transplant Patients
Pancreas Kidney Transplantation (PKT) is the prominent treatment for type 1 diabetic patients with chronic kidney disease and improves patients' outcome.
- Trial name
- ITABI (NCT02234349)
- Testing
- pancreas kidney transplantation, kidney transplantation
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Type 2 Diabetes, Overweight
Effects of Incretin on the Blood Pressure and Lipid in Patients With Overweight or Obese Diabetes
Obesity is one of the characteristics of type 2 diabetes mellitus. Most of the obese diabetes patients are combined with dyslipidemia or hypertension.
- Conditions
- Type 2 Diabetes, Overweight, Obesity, Masked Hypertension
- Trial name
- NCT02503943
- Testing
- "Liraglutide" and "Mitiglinide", "Metformin" and "Mitiglinide", "Mitiglinide"
- Volunteers
- 90 people
- Sponsor
- Third Affiliated Hospital of Third Military Medical University
Gastric Bypass Surgery, Obesity
Mechanisms of Diabetes Control After Weight Loss Surgery
Obesity and type 2 diabetes (T2DM) are increasing in the US. One third of patients seeking bariatric surgery have T2DM. Although all surgeries result in significant weight loss and often 'cure' the T2DM, the rapid onset and the…
- Trial name
- NCT00571220
- Testing
- gastric bypass surgery, Diet induced weight loss
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
Analysing Differences in Glycaemic Control Immediately Post Obesity SurgEry (The ADIPOSE Study)
It is well established that bariatric (weightloss) surgery affords considerable improvement in glycaemic control (control of blood sugar), and in many cases may lead to a complete resolution of type 2 diabetes.
- Trial name
- ADIPOSE (NCT01515059)
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Leicester
Type 1 Diabetes
Incretin Hormones in Type-1 Diabetes Mellitus Glycemic Response in Type-1 Diabetes Mellitus
The purpose of this study is to investigate whether secretion of incretin hormones is intact and to what extent endogenous as well as exogenous GLP-1 controls postprandial glucose excursions in patients with type-1 diabetes…
- Trial name
- NCT00832741
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital