Clinical trials: Indigestion
Functional Dyspepsia
To Evaluate the Efficacy of Z-338 in Subjects With Functional Dyspepsia
To Evaluate the efficacy of Z-338 in subjects with Functional Dyspepsia, focusing on the assessment of subjective symptoms in order to further determine the optimal dosage and efficacy parameters for PhaseIII clinical trials.
- Trial name
- NCT00333372
- Testing
- Z-338
- Where
- Japan
- Volunteers
- 440 people
- Sponsor
- Zeria Pharmaceutical
Functional Dyspepsia
A Study to Demonstrate the Efficacy and Safety of Motilitone®
This is a phase IV , comparative study to evaluate the efficacy and safety of Motiltone® in treatment of the patients with functional dyspepsia.
- Trial name
- NCT01817465
- Testing
- Motilitone ®, Pantoline®, Motilitone® and Pantoline®
- Where
- South Korea
- Volunteers
- 389 people
- Sponsor
- Dong-A ST Co., Ltd.
Dyspepsia
Effect of Genetic Association With Functional Dyspepsia and Mood Disorders
Background: Functional dyspepsia (FD) is one of the commonest digestive disorders. The pathophysiology of functional dyspepsia is uncertain. Risk factors include genetics, gender, age, helicobacter pylori infection, etc.
- Trial name
- FDFDR (NCT02282995)
- Where
- Hong Kong
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Dysbiosis
PPI and Microbiome in Healthy Volunteers and Functional Dyspepsia
Prospective interventional study of the effect of PPI on the duodenal microbiome in healthy volunteers and functional dyspepsia patients
- Trial name
- NCT03545243
- Testing
- Pantoprazole 40mg, PPI withdrawal
- Where
- Belgium
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Helicobacter Pylori Infection, Dyspepsia
Control of Helicobacter Pylori Infection by Dietary Supplementation With Lactobacillus Reuteri
Helicobacter pylori colonizes approximately to 50% of the world-wide population. There is an exigency to find routes alternating to control the infection with an ample perspective but without the complications of induction of…
- Trial name
- NCT01028690
- Testing
- Lactobacillus reuteri
- Where
- Mexico
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centro Regional para el Estudio de las Enfermedades Digestivas
Gastroparesis, Functional Dyspepsia
Prokinetics and Body Surface Gastric Mapping in Dyspeptic Patients: Baseline and Treatment Effects
Functional dyspepsia and gastroparesis are common stomach disorders with symptoms like early satiety, nausea, and abdominal pain, and are often evaluated with gastric emptying tests, although the correlation with symptoms is…
- Trial name
- NCT06854120
- Testing
- Gastric Alimetry
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 125 people
- Sponsor
- University of Auckland, New Zealand
Dyspepsia
Antibiotic Resistant Helicobacter Pylori in Rajavithi Hospital
Peptic ulcer disease is the most common gastrointestinal disease. Antibiotic resistant Helicobacter pylori is a major problem worldwide.
- Trial name
- NCT00285688
- Testing
- gastroscopic examination
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Functional Dyspepsia
From the Biomedical to the Biopsychosocial Model, From Theory to Practice
This study aims to evaluate, in patients with functional dyspepsia, a model example of medical care based upon the biopsychosocial model (called: the therapeutic encounter) compared with standard medical care based upon the…
- Trial name
- NCT01456273
- Testing
- Traditional Medical Consultation, Therapeutic Encounter
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- Faculdade de Medicina do ABC
Dyspepsia
Gastric Barrier Dysfunction of Functional Dyspepsia and Therapeutic Response to Puyuanhewei Detected by Endomicroscopy
Functional dyspepsia might have impaired gastric mucosal dysfunction and Puyuanhewei may be helpful to improve the symptoms of FD.
- Trial name
- NCT02465996
- Testing
- pCLE examination, Puyuanhewei
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shandong University
Gut Health, Microbiome
A Clinical Trial to Evaluate the Effects of a Fibre Supplement on Microbiome and Gut Health
This study will evaluate the effects of the Artah Essential Fibre+ supplement on the microbiome and gut health over an 8-week period.
- Conditions
- Gut Health, Microbiome, Bloating, Indigestion
- Trial name
- NCT07781488
- Testing
- Essential Fibre+
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Artah Nutrition Limited
Functional Dyspepsia, Depression
Zuojin Wan Combined With Rabeprazole or Mosapride for the Treatment of Functional Dyspepsia Combined With Depression
To evaluate the symptom improvement of Zuojinwan combined with rabeprazole or Zuojinwan combined with a mosapride regimen in patients with functional dyspepsia combined with depression (liver-stomach depression-heat type) using…
- Trial name
- NCT06481371
- Testing
- zuojinwan, Rabeprazole sodium enteric-coated tablets, mosapride citrate
- Volunteers
- 120 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Functional Gastrointestinal Disorders
GLP-1 Inhibits Prandial Antro-duodeno-jejunal Motility in Humans
The inhibitory effect of low dose GLP-1 is investigated on prandial motility of the stomach, duodenum and jejunum in vivo in humans.
- Trial name
- GLPMOT (NCT02731664)
- Testing
- GLP-1, Intravenous saline
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Functional Dyspepsia, Gastric Emptying
Effect Of Itopride On Gastric Emptying And Accommodation In Patients With Functional Dyspepsia
Pathogenesis of functional dyspepsia is poorly understood. Gastrointestinal motor abnormalities, Helicobacter pylori infection, impaired gastric accommodation to a meal, hypersensitivity of the afferent nerves of the gut…
- Conditions
- Functional Dyspepsia, Gastric Emptying, Gastric Accommodation
- Trial name
- EIGEAPFD (NCT01226134)
- Testing
- Itopride,
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Aga Khan University
Gastrointestinal Motility Disorders in Children, Functional Gastrointestinal Disorders
BSGM to Evaluate Patients With GI Symptoms
The goal of this observational study is to learn about gastric myoelectric activity in children with GI symptoms. The main question it aims to answer is which patterns or signals are associated with GI symptoms as measured by a…
- Conditions
- Gastrointestinal Motility Disorders in Children, Functional Gastrointestinal Disorders, Gastroparesis, Dyspepsia and Other Specified Disorders of Function of Stomach
- Trial name
- NCT05880199
- Testing
- Body surface gastric mapping device
- Where
- 5 sites in United States
- Volunteers
- 685 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Heterotopic Gastric Mucosa of the Proximal Esophagus, Gastric Inlet Patches
Symptoms and Quality of Life in Patients With Heterotopic Gastric Mucosa (HGM)
The goal of this observational study is to learn whether heterotopic gastric mucosa (HGM) in the upper esophagus is associated with swallowing difficulties (dysphagia) in adults undergoing a medically indicated gastroscopy.
- Conditions
- Heterotopic Gastric Mucosa of the Proximal Esophagus, Gastric Inlet Patches, Dysphagia, Dyspepsia
- Trial name
- SYM-HGM (NCT07510984)
- Where
- Germany
- Volunteers
- 721 people
- Sponsor
- Knappschaft Kliniken GmbH
Functional Gastrointestinal Disorders, Dyspepsia
Stigma and Efficacy of Zhizhu Kuanzhong Capsules
Antidepressants are effective in patients with functional dyspepsia (FD), however, the stigma related with FD and antidepressants could affect treatment adherence and efficacy.
- Conditions
- Functional Gastrointestinal Disorders, Dyspepsia, Psychosomatic Disorder
- Trial name
- NCT05107999
- Testing
- Zhizhu Kuanzhong capsules (ZZKZ), Doxepin Hydrochloride (Doxepin)
- Where
- China
- Volunteers
- 76 people
- Sponsor
- RenJi Hospital
Gastroparesis
Prucalopride Versus Placebo in Gastroparesis
Controlled cross-over study of prucalopride 2 mg daily or placebo in gastroparesis (idiopathic or diabetic). Patients will be randomized to 4 week treatment with the first regimen (double-blind), followed by a 2-week washout and…
- Trial name
- NCT02510976
- Testing
- prucalopride
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Functional Dyspepsia
Probiotics in Functional Dyspepsia
The goal of this clinical trial is to learn whether a multi-strain probiotic can reduce digestive symptoms and improve quality of life in adults with functional dyspepsia.
- Trial name
- ProPepsis (NCT07276009)
- Testing
- Lactobacillus
- Where
- Ukraine
- Volunteers
- 60 people
- Sponsor
- Nordic Biotic Sp. z o.o.
Functional Dyspepsia
Clinical Trial to Assess the Efficacy and Safety of Combination Therapy of Motireb 5/100 mg in Functional Dyspepsia Patients.
A phase Ⅲ, multi-center, randomized, double-blinded, placebo and active comparator clinical trial to assess the efficacy and safety of combination therapy of Motireb 5/100 mg in functional dyspepsia patients.
- Trial name
- NCT02831543
- Testing
- Motireb 5/100 mg, Mosapride citrate
- Where
- South Korea
- Volunteers
- 354 people
- Sponsor
- IlDong Pharmaceutical Co Ltd
Functional Gastrointestinal Disorders, Irritable Bowel Syndrome
ICBT for Pain-predominant FGIDs in Children and Adolescents: an Implementation Study.
This open trial aims to evaluate feasibility and preliminary effectiveness of an internet-delivered CBT-program for children and adolescents with functional gastrointestinal disorders when implemented in regular care.
- Conditions
- Functional Gastrointestinal Disorders, Irritable Bowel Syndrome, Dyspepsia, Functional Abdominal Pain
- Trial name
- NCT03252743
- Testing
- Exposure-based internet-delivered CBT
- Where
- Sweden
- Volunteers
- 68 people
- Sponsor
- Karolinska Institutet