Clinical trials: Indigestion
Non Ulcer Dyspepsia
Effect of Nortriptyline on Abdominal Pain/Discomfort and Quality of Life in Patients With Nonulcer Dyspepsia
The purpose of this study is to determine if use of Nortriptyline will improve symptoms and quality of life in patients who have nonulcer dyspepsia.
- Trial name
- NCT00547703
- Testing
- Nortriptyline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The Cleveland Clinic
Dyspepsia and Other Specified Disorders of Function of Stomach
Functional Dyspepsia Treatment Trial
Functional dyspepsia is a common gastrointestinal disorder. Symptoms can include stomach pain or discomfort, bloating, fullness after eating meals, and nausea.
- Trial name
- FDTT (NCT00248651)
- Testing
- Amitriptyline, Escitalopram
- Where
- 8 sites in United States, Canada
- Volunteers
- 292 people
- Sponsor
- Mayo Clinic
Psychogenic Dyspepsia
Clinical Improvement and in Quality of Life-Functional Dyspepsia-
Functional dyspepsia (FD)is defined as the presence of symptoms thought to originate in the gastroduodenal region with no evidence of structural disease that is likely to explain the symptoms.
- Trial name
- NCT01802710
- Testing
- Psychological support, No intervention
- Where
- Spain
- Volunteers
- 158 people
- Sponsor
- Hospital Galdakao-Usansolo
Functional Gastrointestinal Disorders, Irritable Bowel Syndrome
Does Improving Vagal Tone Increase Mitochondrial Bioenergetics
This study evaluates the effect of auricular neurostimulation on mitochondrial bioenergetics and inflammation through vagal nerve modulation via non-invasive percutaneous electrical nerve field stimulator in children with…
- Conditions
- Functional Gastrointestinal Disorders, Irritable Bowel Syndrome, Dyspepsia, Functional Abdominal Pain Syndrome
- Trial name
- NCT03931330
- Testing
- Percutaneous neurostimulation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Medical College of Wisconsin
Gastroparesis, Dyspepsia
Efficacy and Safety of Cannabidiol for Gastroparesis and Functional Dyspepsia
Researchers are looking at the effects of a cannabidiol medication on stomach function in people with gastroparesis (a paralyzed stomach) and people with dyspepsia (an upset stomach caused by improper functioning of the stomach's…
- Trial name
- NCT03941288
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Mayo Clinic
Gastroesophageal Reflux Disease With Dyspepsia Symptoms
Lansoprazole Tablets Special Drug Use Surveillance Gastroesophageal Reflux Disease With Dyspepsia Symptoms
To evaluate the efficacy of 4-week lansoprazole (Takepron) therapy for subjective symptomatic improvement in gastroesophageal reflux disease patients with dyspepsia symptoms
- Trial name
- LEGEND (NCT01990339)
- Testing
- Lansoprazole
- Volunteers
- 14,965 people
- Sponsor
- Takeda
Dyspepsia, Compliance
Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia
The study hypothesis is appropriate clinician-patient communication that provides explanations of the reasons for psychoactive drug prescriptions based on the generation of FD symptoms and the drugs' effects might improve…
- Conditions
- Dyspepsia, Compliance, Depression
- Trial name
- NCT01851863
- Testing
- Omeprazole, Flupentixol-Melitracen(psychological and GI) + Omeprazole, Flupentixol-Melitracen(psychological) + Omeprazole
- Where
- China
- Volunteers
- 262 people
- Sponsor
- RenJi Hospital
Dyspepsia
Comparison of Pantoprazole and Ranitidine in Dyspepsia
The H0 hypothesis of the study is there is no difference between pantoprazole and ranitidine in treating patients presented with dyspepsia to the emergency department.
- Trial name
- NCT01737840
- Testing
- Pantoprazole, Ranitidine
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Akdeniz University
Functional Dyspepsia
The Efficacy and Safety Study of Rikkunshito in Patients With Functional Dyspepsia
The purpose of this study is to assess the efficacy and safety of Rikkunshito compared to placebo in Japanese subjects with Functional Dyspepsia (FD).
- Trial name
- NCT02037776
- Testing
- Rikkunshito
- Where
- Japan
- Volunteers
- 128 people
- Sponsor
- Osaka City University
Dyspepsia, Emergency
Symptomatic Relief of Acute Dyspeptic Pain in Emergency Department With Pantoprazole
The purpose of this study is to evaluate the immediate synergistic effect on the relief of severe acid-related dyspeptic pain by adding intravenous pantoprazole to the combination of oral antacid and antispasmodic agent (the…
- Conditions
- Dyspepsia, Emergency, Pain
- Trial name
- NCT01281501
- Testing
- Normal saline, Pantoprazole, Oral antacid
- Where
- Thailand
- Volunteers
- 87 people
- Sponsor
- Chulalongkorn University
Helicobacter Pylori Infection, Dyspepsia
ERADICATE Hp2 - Treating Helicobacter Pylori With RHB-105 Compared to Active Comparator
The "test and treat" strategy for treating dyspeptic patients who are H. pylori positive is rapidly becoming the standard of care. This study will test the effectiveness of RHB-105, a new triple therapy to treat H.
- Trial name
- ERADICATE Hp2 (NCT03198507)
- Testing
- RHB-105, Active Comparator
- Where
- 55 sites in United States
- Volunteers
- 455 people
- Sponsor
- RedHill Biopharma Limited
Functional Dyspepsia
A Study of E3810 for Japanese Subjects With Functional Dyspepsia (SAMURAI Study: Suppression of Acid Milieu With Rabeprazole Improving Functional Dyspepsia ) (Study E3810-J081-204)
The purpose of this study is to assess the efficacy and safety of rabeprazole compared to placebo in Japanese subjects with Functional Dyspepsia.
- Trial name
- NCT01089543
- Testing
- Rabeprazole
- Where
- 46 sites in Japan
- Volunteers
- 338 people
- Sponsor
- Eisai Co., Ltd.
Dyspepsia, Healthy
Effect of Secretin in Functional Dyspepsia and Healthy Subjects
Insights into the pathophysiology of functional dyspepsia, with recent demonstration of inflammation with eosinophilia and mastocytosis in the duodenum (3, 6, 7), providing a possible lead toward reduced secretion of a potential…
- Trial name
- NCT03617861
- Testing
- Human Secretin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Functional Dyspepsia
Functional Dyspepsia Hypnosis
The purpose of this study is to evaluate the efficacy of a hypnotherapy treatment program for functional dyspepsia that can be self-administered using on-line audio recordings. This is a non-randomized study.
- Trial name
- NCT03884270
- Testing
- Hypnotherapy
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Sarah Kinsinger
Functional Abdominal Pain, Functional Dyspepsia
Efficacy of Open Label Placebo in Children With FGIDs
This study is aimed at investigating the efficacy of placebo for symptom relief in children with abdominal pain related functional gastrointestinal disorders.
- Conditions
- Functional Abdominal Pain, Functional Dyspepsia, Irritable Bowel Syndrome, Functional Gastrointestinal Disorders
- Trial name
- Placebo (NCT02389998)
- Testing
- Hyoscyamine
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Boston Children's Hospital
Dyspepsia
Carbon-13 (13C)-Spirulina Platensis Gastric Emptying Breath Test (GEBT)
The purpose of this study is to compare stomach emptying using 13C-Spirulina platensis breath test and scintigraphy in healthy subjects and subjects with dyspepsia.
- Trial name
- NCT01248221
- Testing
- [13C]-Spirulina platensis and 99mTc sulfur colloid
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dyspepsia
Clinical Trial of Efficacy and Safety of Kolofort in Functional Dyspepsia Patients
Purpose of the study: To obtain additional data on efficacy and safety of Kolofort in the treatment of patients with functional dyspepsia.
- Trial name
- NCT03119766
- Testing
- Kolofort
- Where
- 32 sites in Russia
- Volunteers
- 370 people
- Sponsor
- Materia Medica Holding
Post-cholecystectomy Gastrointestinal Spasms
Effectiveness of Duspatalin® in Patients With Post-cholecystectomy Gastrointestinal Spasm
Prospective, multicenter, non-comparative, observational program designed to assess the effectiveness of a 2-6 weeks treatment with Duspatalin® 200mg bis in die = twice a day (BID) and changes in quality of life in patients with…
- Trial name
- ODYSSEY (NCT02260154)
- Testing
- Mebeverine
- Where
- 21 sites in Russia
- Volunteers
- 220 people
- Sponsor
- Abbott
Gastroparesis
Placebo Controlled Trial of Botulinum Toxin for Gastroparesis
It is hypothesized that in some patients with gastroparesis increased pyloric tone may be a contributing feature. Botox relaxes the pylorus so that food can empty the stomach more rapidly.
- Trial name
- NCT00372970
- Testing
- Botulinum toxin A
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Temple University
Functional Gastrointestinal Disorders, Vagus Nerve Autonomic Disorder
A Study of Randomized Sham-control Auricular TENS Unit Stimulation in Pediatric Functional Gastrointestinal Disorders
The purpose of this study is to see if using a micro-current through a device called a TENS (Transcutaneous Electrical Nerve Stimulator) unit helps to improve functional gastrointestinal disorder (FGID) symptoms in children by…
- Conditions
- Functional Gastrointestinal Disorders, Vagus Nerve Autonomic Disorder, Irritable Bowel Syndrome, Nausea
- Trial name
- NCT04247100
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Gisela Grotewold Chelimsky