Clinical trials: Individual Difference
Infertility, Sterility
Real-world Evidence on Follitropin Delta Individual Dosing
As part of the in vitro fertilisation treatment, ovarian stimulation is routinely performed. For this purpose, FSH preparations are used.
- Trial name
- NCT05173597
- Testing
- Follitropin delta
- Where
- Germany
- Volunteers
- 850 people
- Sponsor
- University of Luebeck
Healthy, Obesity
A Study in Healthy People or Otherwise Healthy With Overweight or Obesity to Compare 2 Formulations of Survodutide Given in Different Ways, Either as a Pre-filled Syringe or a Pen-like Injector
The goal of this study is to find out whether different formulations of survodutide given by different delivery methods is taken up in the body in a similar way. Participants visit the study site regularly.
- Trial name
- NCT07413913
- Testing
- Survodutide formulation A, Survodutide formulation B2
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Inflammation Biomarkers, Inflammation
Individual Differences in Acute Response to Experimental Inflammation: Microcirculatory Changes and Psychological Predictors
The physiological and behavioral responses to inflammatory vary greatly between individuals. The knowlegde about what causes these differences is sparse but plausible explanations are variations in sensitivity to peripheral…
- Trial name
- NCT06618716
- Testing
- endotoxin escherichia coli (E. coli) lipopolysaccharide (LPS), Placcebo
- Where
- Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Sleep, Diabetes
Individual Differences in Diabetes Risk: Role of Slow WaveSleep
This study will examine the relationship between the amount of slow wave sleep (deep sleep) and the ability of the body to bring the blood sugar level to a normal range after receiving glucose.
- Trial name
- NCT00989378
- Testing
- baseline study
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Autism Spectrum Disorder
More and Less Social Comprehension
The goal of this early Phase 1 clinical trial is to assess if the social content of a story impacts autistic children's listening comprehension of stories.
- Trial name
- MLSC (NCT06116552)
- Testing
- More Social Stories, Less Social Stories
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Kansas Medical Center
PreDiabetes
Efficacy of Physical Exercise on Glucose Control in People With Prediabetes
To assess the efficacy of different modalities and frequencies of physical exercise on glycaemic control in adults with prediabetes.
- Trial name
- GLYCEX (NCT05612698)
- Testing
- Aerobic training, Aerobic training plus resistance training, High intensive interval training
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of the Balearic Islands
Behavior, Depressive Disorder
Can Computational Measures of Task Performance Predict Psychiatric Symptoms and Changes in Symptom Severity Across Time
This study investigates the computational mechanisms associated with psychiatric disease dimensions. The study will characterize the relationship between computational parameter estimates of task performance and psychiatric…
- Conditions
- Behavior, Depressive Disorder, Anxiety Disorders, Obsessive Compulsive Disorder (OCD)
- Trial name
- CABxtime (NCT06705179)
- Testing
- Behavioral task performance
- Where
- 2 sites in United States
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- California Institute of Technology
Support Persons, Family Members
Recovery Inspired Support Engagement (RISE) Pilot
The goal of this clinical trial is to learn if a 1-on-1 support program is easy to complete and acceptable for people supporting loved ones who have recently received treatment for substance use.
- Conditions
- Support Persons, Family Members, Chosen Family, Romantic Partners
- Trial name
- (RISE) (NCT07519759)
- Testing
- ITC
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Solid Tumors
A Study to Test Different Doses of BI 1831169 Alone and in Combination With an Anti-PD-1 Antibody in People With Different Types of Advanced Cancer (Solid Tumors)
This study is open to adults with different types of advanced cancer (solid tumors) that are accessible for injection and/or biopsy.
- Trial name
- NCT05155332
- Testing
- BI 1831169, anti-PD-1 antibody
- Where
- 33 sites in United States, Australia and 8 more
- Volunteers
- 190 people
- Sponsor
- Boehringer Ingelheim
Borderline Personality Disorder, Suicide
Comparing Treatments for Self-Injury and Suicidal Behavior in People With Borderline Personality Disorder
This study will compare the effectiveness of two treatments, dialectical behavior therapy versus fluoxetine with clinical management, for reducing the risk of self-injury and suicidal behavior in people with borderline…
- Trial name
- NCT00834834
- Testing
- Fluoxetine, DBT, Citalopram
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- New York State Psychiatric Institute
Elderly (People Aged 65 or More), Balance
Figure-of-eight Backward Walk Test in Elderly
Mobility is a fundamental element of healthy aging. Balance is a necessary function during mobility for all movements throughout life in elderly individuals.
- Conditions
- Elderly (People Aged 65 or More), Balance, Dynamic Balance, Backward Walking
- Trial name
- elderly (NCT07180030)
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Knee Osteoarthritis (OA), Chronic Pain
Individual Differences in Gait and Osteoarthritis Pain
The goal of this observational study is to look at inter-individual differences in knee osteoarthritis (OA) walking pain and performance.
- Conditions
- Knee Osteoarthritis (OA), Chronic Pain, Chronic Knee Pain
- Trial name
- INDIGO (NCT07308873)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
Individuality
Acute Physiological Effects of Electronic Sigarette vs Cigarette Smoking
Because e-cigarettes do not contain or burn tobacco, they do not appear to deliver the known toxins found in conventional cigarette smoke.However e-Cigarettes with low dose of tobacco were found to have immediate adverse…
- Trial name
- NCT02102191
- Testing
- e-cigarette, cigarette
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Healthy
This Study in Healthy Men Tests How Different Doses of BI 1358894 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Tests How BI 1358894 Affects the Way the Body Breaks Down Midazolam
The primary objective of the trial is to investigate the safety and tolerability of BI 1358894 in healthy male subjects following oral administration of multiple rising doses over 14 days.
- Trial name
- NCT03754959
- Testing
- BI 1358894, Midazolam
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy People to Test How 2 Different Formulations of a Combination Treatment (Vicadrostat and Empagliflozin) Are Taken up in the Body and How Food Influences the Amount of the Medicines in the Blood
To investigate the relative bioavailability of two different vicadrostat/empagliflozin combinations. Additionally, the trial investigates the effect of food on the pharmacokinetics of the vicadrostat/empagliflozin.
- Trial name
- NCT07133399
- Testing
- vicadrostat / empagliflozin combination 1, vicadrostat / empagliflozin 2
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Human NiV Infection
Community Intervention to Prevent Nipah Spillover
Several human Nipah virus (NiV) outbreaks have occurred in Bangladesh since 2001with 71% case fatality. Outbreak investigations have repeatedly identified drinking fresh date palm sap as a risk factor for NiV transmission.
- Trial name
- NCT01811784
- Testing
- Ask people not to drink raw sap, Ask people not to drink sap or drink sap from skirt protected trees, No Intervention
- Where
- 4 sites in Bangladesh
- Volunteers
- 7,782 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Solid Tumors, KRAS Mutation
A Study to Test Different Doses of BI 3011441 in Japanese People With Different Types of Advanced Cancer (NRAS/KRAS Mutation Positive)
This study is open to Japanese adults with different types of advanced cancer that are positive for NRAS/KRAS mutations. This is a study in people for whom previous treatment was not successful or no standard treatment exists.
- Trial name
- NCT04742556
- Testing
- BI 3011441
- Where
- 3 sites in Japan
- Volunteers
- 15 people
- Sponsor
- Boehringer Ingelheim
Autistic Spectrum Disorders
A Pilot Trial of a Developmental, Individual-Difference, Relationship-Bases (DIR)/Floortime for Children With Autistic Spectrum Disorders
Thirty two children age 2-6 years are recruited into the study and the randomization will be stratified for chronological age and symptom severity into 2 main groups, intervention and control.
- Trial name
- DIR (NCT00954083)
- Testing
- DIR/Floortime, Routine care
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Alcohol Use Disorder (AUD), Subjective Response to Alcohol (SR)
Impulsivity and Alcohol Response
Impulsivity, a well-known risk factor predicting negative outcomes, refers broadly to a proclivity towards rapid action with a suboptimal regard for future consequences.
- Trial name
- IDEA (NCT03736343)
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Florida
Burnout, Professional, Stress, Psychological
The Effect of Laughter Yoga on Individual and Organizational Outcomes in Nurse Managers
The goal of this clinical trial is to learn if laughter yoga can improve both individual and organizational outcomes in nurse managers.
- Conditions
- Burnout, Professional, Stress, Psychological, Compassion Fatigue, Quality of Life
- Trial name
- NCT07235735
- Testing
- Laughter Yoga Program
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University