Clinical trials: Individual Difference
Type 2 Diabetes
Educative Intervention to Improve Type 2 Diabetes Mellitus Control in Corrientes
Objective: To evaluate the effect of system interventions (data recording procedures and complete coverage of medications and supplies) with or without physician and/or patient education, upon the psychological, clinical…
- Trial name
- PRODIACOR (NCT01456806)
- Testing
- Education
- Where
- Argentina
- Volunteers
- 468 people
- Sponsor
- Centro de Endocrinologia Experimental y Aplicada
Violence, Parenting
Evaluating the Effectiveness of the Common Elements Treatment Approach (CETA) in Peru: Mechanisms of Individual and Intergenerational Change
Recent advances in intervention research have revealed the promise of transdiagnostic, modular approaches implemented by lay paraprofessionals for the treatment of the most prevalent mental health concerns in settings affected by…
- Conditions
- Violence, Parenting, Poverty, Depression
- Trial name
- NCT07667738
- Testing
- Common Elements Treatment Approach, Enhanced Case Managment
- Where
- Peru
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Osteoarthritis, Knee, Osteoarthritis, Hip
Barriers and Faciliators for Physical Activity in People With RMDs
The aim of this project is to systematically survey and explore barriers and facilitators for the implementation of physical activity according to the physical activity recommendations of the European Alliance of Associations for…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Rheumatoid Arthritis, Axial Spondyloarthritis
- Trial name
- COPA (NCT06514443)
- Testing
- survey
- Volunteers
- 400 people
- Sponsor
- Anne-Kathrin Rausch
Heart Failure
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
This study will look into how CDR132L (a potential new medicine) works on the structure and function of the heart in people living with heart failure.
- Trial name
- 8212-Preserved (NCT06979362)
- Testing
- CDR132L
- Where
- 118 sites in United States, Canada and 7 more
- Volunteers
- 200 people
- Sponsor
- Novo Nordisk A/S
Sleep
Energy-efficient and Health Promoting Light for Elderly People
to investigate the effect of two lightning conditions on sleep hypothesizing that sleep length is influenced by the color of light during daytime
- Trial name
- light-age (NCT02216318)
- Testing
- blue light
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Glostrup University Hospital, Copenhagen
Healthy, Controlled Feeding Trial
Gut Microbial Metabolites of Apple Polyphenols
The goal of this controlled feeding trial is to learn about the metabolism of polyphenols, a common class of compounds found in plant-based foods, by the gut microbiome.
- Trial name
- GutMMAP (NCT06107192)
- Testing
- Dietary intervention - apple catechin diet, Dietary intervention - low catechin diet
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Eye Movements, Attention
An Investigation of Attentional and Inhibitory Processes During Active Visual Search in Humans
The goal of this study is to investigate the finding that there are large individual differences in how participants move their eyes during active visual search.
- Conditions
- Eye Movements, Attention, Executive Function
- Trial name
- NCT06587113
- Testing
- Contour Search Task, Stop signal Task, Useful field of View
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Gender Dysphoria
Evaluation of the Variation in Quality of Life During Medical Transition for Transgender People.
Transgender people can benefit from psychological, psychiatric, endocrinological support, sexual reassignment surgery, sexology support and dermatological care. The value of transitional care courses is scientifically recognized.
- Trial name
- TRANS'ITION (NCT05273112)
- Where
- 13 sites in France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Lille
Healthy
A Study in Healthy People to Test How Zongertinib is Taken up in the Body When Given as Tablets Made by Two Different Manufacturers With or Without Food
The main objective of this trial is to establish the bioequivalence of Zongertinib tablets from two different manufacturers following oral administration.
- Trial name
- NCT07789028
- Testing
- Zongertinib, Formulation A, reference product, Zongertinib Formulation B, test product
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Stroke
Characterising Arm Recovery in People With Severe Stroke
The main goal of this program of research is to advance our understanding of how the severely damaged brain changes over the first 12-months post stroke.
- Trial name
- CARPSS (NCT02464085)
- Testing
- Longitudinal evaluation of recovery
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Neck Pain, Chronic Neck Pain
Effects of Different Exercise Protocols on Physical and Cognitive Changes in People With Chronic Neck Pain
This study aims to investigate the effects of different exercise approaches on physical status, cognitive functions, brain structures, and blood biomarkers in individuals with chronic neck pain.
- Trial name
- NCT07432425
- Testing
- Aerobic exercise, Strengthening exercise, Posture and strentching exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Hacettepe University
Parkinson's Disease
Feasibility and Acceptability of a Physical Activity Behavior Change Intervention for Parkinson's Disease
The purpose of this study is to assess the feasibility, in regards to acceptability and implementation, of the Pre-Active PD intervention for increased high intensity goal-directed aerobic exercise engagement in people with…
- Trial name
- Preactive-PD (NCT03696589)
- Testing
- Physical Activity Coaching
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Teachers College, Columbia University
Diet
Microbiome Individuality and Stability Over Time
Microbial derived uremic solutes (p-cresol sulfate, indoxyl sulfate, and phenylacetylglutamine) are present in blood and excreted into the urine.
- Trial name
- MISO (NCT04740684)
- Testing
- Standardized diet
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Stanford University
Stroke
Understanding Different Parameters in Locomotor Training (a Type of Walking Training) for Person After a Stroke
This is a research study to understand how people who have experienced a stroke walk in order to develop better and more effective types of therapy.
- Trial name
- NCT00712179
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Rabies
Clinical Trial of Freeze-dried Human Rabies Vaccine (Without Serum Vero Cells)
This study was intended to explore the safety and immunogenicity of the test vaccine compared to the control vaccine. The trial consisted of two phases. Phase I used an open-ended design.
- Trial name
- NCT05969626
- Testing
- 5-dose group of test vaccine, 5-dose group of control vaccine, 4-dose A group of test vaccine
- Where
- 4 sites in China
- Volunteers
- 2,460 people, healthy volunteers welcome
- Sponsor
- Ningbo Rongan Biological Pharmaceutical Co., Ltd.
Hypertension, Overweight
Effects of Different Aerobic Exercise Programs With Nutritional Interventions in Hypertensive and Overweight People
Obesity and arterial hypertension (HTN) frequently coexist in the same patient. Moreover, the concept that obesity and HTN can be additive in terms of cardiovascular rist is widely accepted.
- Conditions
- Hypertension, Overweight, Sedentary
- Trial name
- EXERDIET-HTA (NCT02283047)
- Testing
- DIET, DIET & MODERATE CONTINUOUS TRAINING, DIET & HIGH VOLUME HIIT
- Where
- Spain
- Volunteers
- 176 people
- Sponsor
- University of the Basque Country (UPV/EHU)
Musculoskeletal, Pain Management
Life-Style Medicine for Chronic Musculoskeletal Pain in Older People
The goal of this clinical trial is to determine the clinical effectiveness of lifestyle medicine in reducing chronic musculoskeletal pain in older adults, as measured by pain intensity, pain interference, self-management…
- Conditions
- Musculoskeletal, Pain Management, Chronic Pain, Musculoskeletal Pain
- Trial name
- lifestyle med (NCT07194239)
- Testing
- Lifestyle medicine Health coaching
- Where
- Hong Kong
- Volunteers
- 268 people
- Sponsor
- Chinese University of Hong Kong
Major Depressive Disorder
An Individual-specific Synchrony Signature
This study aims to establish synchrony as an individual-specific mechanism of therapeutic change and offers novel insights into the mechanisms of curative interpersonal processes.
- Trial name
- SynSig (NCT06749392)
- Testing
- Supportive-expressive treatment
- Where
- Israel
- Volunteers
- 78 people
- Sponsor
- University of Haifa
Cystic Fibrosis (CF), CFTR-related Disorders
A Prospective Study of Advanced Diagnostics in People With an Unclear Diagnosis of Cystic Fibrosis
Sometimes it is very difficult to tell if someone has cystic fibrosis (CF), especially when they have rare CF genes. Without this certainty, they are unlikely to get the correct treatment so their health may be affected.
- Trial name
- ADVANCE-CFTR (NCT07402434)
- Testing
- Rectal Biopsy, Rectal biopsy taken opportunistically during endoscopy procedure for other reasons., Blood test for CFTR Genotyping
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Individual Difference, Food Sensitivity
Investigation of the Perception of Protein Fortified Foods and Beverages
This study aims to investigate whether protein fortification of foods and beverages causes mouthdrying and mucoadhesion and whether this is influenced by age and saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT03798730
- Testing
- Solid Model, Liquid Model
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Reading