Clinical trials: Individual Difference
Type 2 Diabetes
My Diabetes Study - CGM Initiation Approach & Time In Range
This study includes two phases. The purpose of Phase 1 of this study is to understand if there is a difference between two ways of introducing a continuous glucose monitor (CGM) to people with type 2 diabetes (T2D).
- Trial name
- NCT05928572
- Testing
- CGM initiation approach
- Where
- United States
- Volunteers
- 159 people
- Sponsor
- Holly Willis
Hypertension, Portal
A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)
This study is open to adults with liver cirrhosis and high blood pressure in the portal vein (main vessel going to the liver). The purpose of this study is to find out whether a medicine called Avenciguat helps people with this…
- Trial name
- NCT05161481
- Testing
- Avenciguat (BI 685509)
- Where
- 45 sites in United States, Argentina and 20 more
- Volunteers
- 80 people
- Sponsor
- Boehringer Ingelheim
Type 2 Diabetes
Continuous Glucose Monitoring and Behavioral Change Intervention for People With Type 2 Diabetes and Diabetes Distress
The purpose of this study is to use a Personalized Trial (N-of-1) design to test the effect of an intervention that pairs continuous glucose monitoring (CGM) with text message-delivered behavior change interventions for physical…
- Trial name
- NCT05941000
- Testing
- Self-Monitoring of Behavior for Physical Activity, Action Planning for Physical Activity, Self-Monitoring of Behavior for Mood
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Atrophy of Vocal Cord, Presbyphonia
PhoRTE® Therapy Efficacy: In-Person Versus Telehealth
This study compares how well voice therapy works when delivered in-person versus through telehealth for older adults with age-related voice problems.
- Conditions
- Atrophy of Vocal Cord, Presbyphonia, Dysphonia, Glottic Insufficiency
- Trial name
- NCT06934265
- Testing
- exuberant voice therapy
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Healthy
A Study in Healthy People to Test How Empagliflozin is Taken up in the Body When Taken as a Whole Tablet or Dissolved in Water and Mixed With Food
This trial is conducted to test how empagliflozin is taken up in the body when taken as a whole tablet or dissolved in water and mixed with food.
- Trial name
- NCT06962826
- Testing
- Empagliflozin
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Sleep, Circadian Rhythm
Examining the Biological Factors That Affect Sleep Duration
Sleep is necessary for healthy functioning, and people who sleep too little or too much may have an increased risk of developing health problems.
- Conditions
- Sleep, Circadian Rhythm, Cognitive Performance
- Trial name
- NCT00607204
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Acute Myeloid Leukemia
Comparing Different Treatment Lengths for Venetoclax in Older People With Newly Diagnosed Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)
This phase II MyeloMATCH treatment trial compares ASTX727 with standard duration versus shorter duration of venetoclax for the treatment of newly diagnosed acute myeloid leukemia (AML).
- Trial name
- NCT07437950
- Testing
- Biospecimen Collection, Bone Marrow Aspiration, Decitabine and Cedazuridine
- Where
- 52 sites in United States, Puerto Rico
- Volunteers
- 126 people
- Sponsor
- National Cancer Institute (NCI)
Subacromial Impingement Syndrome, Apical Shoulder Pain
Comparison of Dynamic Ultrasound Visual Feedback to Manual Feedback on Scapular Stabilizer Activation and Change in the Subacromial Space in Persons With Pain During Shoulder Elevation
Purpose of the Study This study looks at whether using real-time ultrasound images as feedback can help people better activate two important shoulder muscles-the serratus anterior and lower trapezius-compared to standard verbal…
- Conditions
- Subacromial Impingement Syndrome, Apical Shoulder Pain, Rotator Cuff Syndrome
- Trial name
- SCAP-M-RUSI (NCT07464639)
- Testing
- Verbal and tactile feedback with exercise
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- California State University, Long Beach
Individuality, Healthy Subjects
Milieu Intérieur Collection - Genetic & Environmental Determinants Of Immune Phenotype Variance
The purpose of this study is to assess the determinants of immunologic variance within the general healthy population.
- Trial name
- MI (NCT03905993)
- Volunteers
- 956 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Sleepiness
Effect of Countermeasures on Nocturnal Driving Performance
Sleep deprivation induces degradation of night-time driving ability via sleepiness. Because of conflicts between physiological needs and social or professional activities, it is necessary to develop affordable countermeasure to…
- Trial name
- KILLSLEEP (NCT01070004)
- Testing
- Real driving situation, Driving simulator
- Where
- 2 sites in France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Metastatic Cancer
A Study of Reduced-dose Radiation in People With Metastatic Tumors With a Genetic Change
This study will test whether reduced-dose radiotherapy is an effective treatment for metastatic tumors with an ATM mutation. The researchers want to find the lowest dose of radiation that would still be effective to treat these…
- Trial name
- NCT05010031
- Testing
- Palliative radiotherapy
- Where
- 7 sites in United States
- Volunteers
- 45 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Human Immunodeficiency Virus, Tuberculosis
Preventive Therapy for Tuberculosis in HIV Infected Persons
Title: Evaluation of efficacy of two different preventive therapy regimens for tuberculosis in HIV infected persons Phase: Phase III trial Population: 650 HIV positive patients without tuberculosis Number of sites: Three 1.
- Trial name
- NCT00351702
- Testing
- Isoniazid with Ethambutol
- Where
- India
- Volunteers
- 683 people
- Sponsor
- Tuberculosis Research Centre, India
ESBL Producing E.Coli, ESBL Producing K.Pneumoniae
Epidemiology of Resistant Microbial Strains Among Different Groups of People (Healthy, Infected and Exposed to Animals)
This study investigates carriage rate and risk factors for acquiring multiresistant bacteria (ESBL producing E.coli and K.pneumoniae, carbapenem-resistant and multidrug resistant P.aeruginosa, MRSA and VRE) in hospitalised…
- Conditions
- ESBL Producing E.Coli, ESBL Producing K.Pneumoniae, Multidrug Resistant P.Aeruginosa, Carbapenem Resistant P.Aeruginosa
- Trial name
- ABRESIST (NCT03343119)
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Multiple Sclerosis
Effectiveness of Exergaming in Adittion to Conventional Treatment for Physical Therapy in People with Multiple Sclerosis
The present study aims to evaluate the effectiveness of two different exergaming systems in addition to conventional treatment on physical functional capacity, balance, muscle strength, spasticity in lower limbs and quality of…
- Trial name
- NCT06196866
- Testing
- Conventional Therapy, Nintendo Ring Fit Adventure + Conventional Therapy, Nintendo Wii Fit + Conventional Therapy
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad de Córdoba
Frailty Syndrome
Clinical Intervention in Frail Older People (FRAILCLINIC)
Frailty is the main risk factor for the development of incident disability in older people and one of the most important for other adverse outcomes (death, hospitalisation, falls, and permanent institutionalisation).
- Trial name
- FRAILCLINIC (NCT02643069)
- Testing
- Intervention Geriatric Program
- Where
- Spain
- Volunteers
- 821 people
- Sponsor
- Hospital Universitario Getafe
Stroke
The Effects of Whole Body Vibration in People With Chronic Stroke
Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone…
- Trial name
- NCT03982251
- Testing
- High frequency whole body vibration, Low frequency whole body vibration
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Cognitive Change
Influence of Cognition on Activity and Participation in People With Stroke
If a subject agrees to participate, the primary investigators will collect some basic information including age, height, and weight.
- Conditions
- Stroke, Cognitive Change, Neurological Injury, Cognitive Impairment
- Trial name
- CAPS (NCT05919251)
- Testing
- Ageless Grace
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Saint Joseph's University, Philadelphia
Individuality
Study of Glasgow Coma Scale in Neurological Patients
The assessment of the level of consciousness in patients admitted to intensive care units (ICU) can be complicated because the variables that are evaluated can be interpreted in a different way by different observers.
- Trial name
- NCT01641978
- Where
- Spain
- Volunteers
- 125 people
- Sponsor
- Hospital Universitario Getafe
COPD
A Sedentary Behaviour Reduction Intervention for People With COPD
Chronic obstructive pulmonary disease (COPD) is a major cause of disability. Individuals with COPD are more likely to spend prolonged periods of time in sedentary behaviour (SB) and less in light physical activity compared to…
- Trial name
- NCT04004585
- Testing
- Get Up For Your Health
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- West Park Healthcare Centre
Carcinoma, Squamous Cell of Head and Neck (HNSCC), Melanoma
A Study to Test How BI 765063 and BI 770371 Are Taken up in Tumours of People With Different Types of Advanced Cancer Who Are Also Taking Ezabenlimab
This study is open to adults with advanced head and neck cancer, skin cancer, or non-small cell lung cancer. People can take part if previous treatments were not successful.
- Conditions
- Carcinoma, Squamous Cell of Head and Neck (HNSCC), Melanoma, Non-small Cell Lung Cancer (NSCLC)
- Trial name
- NCT05068102
- Testing
- BI 765063, Ezabenlimab, [89Zr]Zr- BI 765063
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Boehringer Ingelheim