Clinical trials: Individual Difference
Chronic Low Back Pain, Spinal Cord Injury
SERENITY Study of Chronic Pain Interference in Adults
SERENITY is a remote observational study designed to characterize inter-individual differences in chronic pain among adults with chronic low back pain and adults with spinal cord injury-related neuropathic pain.
- Conditions
- Chronic Low Back Pain, Spinal Cord Injury, Neuropathic Pain, Chronic Pain
- Trial name
- SERENITY (NCT07820475)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Minnesota
Cognitive Decline, Cognitive Deficit
Validation Study SCOBES-AR
Purpose of the study The purpose of this study is to evaluate five tests to see if they are suitable for the early detection of cognitive impairment in people over the age of 60.
- Conditions
- Cognitive Decline, Cognitive Deficit, Cognitive Impairment
- Trial name
- NCT04204239
- Where
- Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- FH Joanneum Gesellschaft mbH
HIV Infection, Combined Antiretroviral Therapy
Impacts of Different ART Regimens on Lipid Metabolism in People Living With HIV
To compare the dynamic changes of lipid metabolism of people living HIV who treated with different antiretroviral therapy (ART) regimens such as Biktarvy EVG/c/TAF/FTC, DTG/FTC/TDF, TDF/3TC/EFV, etc.
- Trial name
- ART (NCT06019273)
- Where
- China
- Volunteers
- 180 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Healthy
A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up in the Body
The main objective of this trial is to investigate relative bioavailability of BI 456906 reference formulation (Formulation A) vs. BI 456906 test formulation (Formulation B2).
- Trial name
- NCT07071974
- Testing
- BI 456906 formulation A, BI 456906 formulation B2
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Obesity, Cardiometabolic Syndrome
A Study Comparing the Health Effects of Two Diets Following UK Dietary Guidance in People Living With Overweight or Obesity
There are two parts to this study: 1. The investigators will study if the benefit from eating a healthy, balanced diet depends on the types of food processing in the diet.
- Conditions
- Obesity, Cardiometabolic Syndrome, Overweight
- Trial name
- UPDATE (NCT05627570)
- Testing
- Healthy, balanced Diet A, Healthy, balanced Diet B, Behavioural support intervention
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University College, London
Multiple Sclerosis
The Effects of Different Medical Marijuana Strains on Motor and Cognitive Function in People With Multiple Sclerosis
Over the last two years, the United States has witnessed enormous change concerning the acceptance of marijuana. The number of persons with MS (PwMS) using cannabis to treat their symptoms is expected to rise, and it is important…
- Trial name
- NCT03172741
- Testing
- Medical Marijuana
- Sponsor
- Colorado State University
Obesity
A Study to Learn How Different Amounts of the Study Medicine Called PF-08642534 Are Tolerated and Act in the Body of People Who Have Obesity
This study will look at a study drug called PF-08642534 in people with obesity (have too much body weight) to see: if participants can take different amounts (doses) of the study drug in a safe way and how adults with obesity…
- Trial name
- NCT07731139
- Testing
- PF-08642534
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pfizer
Mindfulness, Depression
Internet-based Mindfulness-based Training (iMBT) for People With Depression
The research goals of this randomized controlled trial are to determine the feasibility and the mechanism of change of iMBT that has been developed using the Acceptance Checklist for Clinical Effectiveness Pilot Trials.
- Trial name
- NCT05410132
- Testing
- Internet-delivered Mindfulness Based Training (iMBT)
- Where
- Hong Kong
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Type2 Diabetes, NAFLD
Effects of VLCD and Bariatric Surgery in Patients With Type 2 Diabetes
The investigators are therefore interested to explore the effects of VLCD and different bariatric surgery procedures to changes in the physical deposition of fat in organs which regulate glucose metabolism (i.e.
- Conditions
- Type2 Diabetes, NAFLD, Obesity
- Trial name
- BARIATRICMRI (NCT05092399)
- Testing
- Bariatric Surgery
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University of Nottingham
Alcohol Use Disorder (AUD), Subjective Response to Alcohol (SR)
Impulsivity and Alcohol Response
Impulsivity, a well-known risk factor predicting negative outcomes, refers broadly to a proclivity towards rapid action with a suboptimal regard for future consequences.
- Trial name
- IDEA (NCT03736343)
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Florida
Multiple Sclerosis
Internet-based Physical Activity Promotion and Exercise Prescription for People With Multiple Sclerosis
The aim of the study is to evaluate the effects of a 12-week internet-based exercise and physical activity promotion intervention on physical activity.
- Trial name
- ms bewegt (NCT04367389)
- Testing
- Physical activity promotion, Exercise
- Where
- 9 sites in Germany
- Volunteers
- 62 people
- Sponsor
- University of Erlangen-Nürnberg
Healthy Aged Volunteers
The Influence of Different Types of Physical Exercise on Immunosenescence in Elderly Persons
This study aims to identify the mechanisms by which physical exercise can counter inflammation and improve immune function in older persons.
- Trial name
- NCT04534049
- Testing
- Intensive Strength Training (IST), Strength Endurance Training (SET), Flexibility Training (FT)
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Diabetic Foot
Clinical Efficacy of Different Revision Times in the Reulceration Rate in Persons with Diabetes and Remission
The goal of this three arms randomized clinical trial is to compare different revision times in persons with diabetes at high risk of suffering a diabetic foot reulceration (patients in remission).
- Trial name
- Diatime (NCT06143215)
- Testing
- 4 weeks revision
- Where
- Spain
- Volunteers
- 148 people
- Sponsor
- Universidad Complutense de Madrid
Solid Tumours
A Study to Test How Well Different Doses of BI 3822971 Are Tolerated by People With Advanced Cancer (Solid Tumours)
This study is open to adults with advanced or metastatic solid cancer, such as non-small cell lung cancer, head and neck squamous cell carcinoma, triple-negative breast cancer, esophageal squamous cell carcinoma, bladder cancer…
- Trial name
- NCT07744152
- Testing
- BI 3822971
- Where
- 11 sites in Belgium, China and 3 more
- Volunteers
- 137 people
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy People to Compare Two Different Sifrol® Tablets
The main objective of this trial is to establish the bioequivalence of Sifrol® tablets manufactured at two different sites.
- Trial name
- NCT06457204
- Testing
- Pramipexole manufactured in Ingelheim, Pramipexole manufactured in Ennigerloh
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Type 2 Diabetes
Change of Lifestyle by Persons in Risk of Type 2 Diabetes
We know that changing lifestyle can prevent type 2 diabetes. The challenge is how to help people changing their lifestyle. We have people in 2 groups: half of them is meeting in grops of 10 persons (interventiongroup), the other…
- Trial name
- NCT00202748
- Testing
- Increase in activity to control weight, Increase in activity to control weight.
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- Sorlandet Hospital HF
Stroke
Characterising Arm Recovery in People With Severe Stroke
The main goal of this program of research is to advance our understanding of how the severely damaged brain changes over the first 12-months post stroke.
- Trial name
- CARPSS (NCT02464085)
- Testing
- Longitudinal evaluation of recovery
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Neck Pain, Chronic Neck Pain
Effects of Different Exercise Protocols on Physical and Cognitive Changes in People With Chronic Neck Pain
This study aims to investigate the effects of different exercise approaches on physical status, cognitive functions, brain structures, and blood biomarkers in individuals with chronic neck pain.
- Trial name
- NCT07432425
- Testing
- Aerobic exercise, Strengthening exercise, Posture and strentching exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Hacettepe University
Family Conflict, Family Relations
Parent Web - Support for Families With Young People
To test an online parent training program. Relative to a randomized wait-list control group, those in the Parent Web (PW) will show benefits on well-being, parenting, stress, youth mental health.
- Conditions
- Family Conflict, Family Relations, Family Dysfunction
- Trial name
- PWS2 (NCT06533735)
- Testing
- Parent Web
- Where
- Sweden
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Stockholm University
Diabetes Mellitus, Skin and Connective Tissue Diseases
Treatment Effects of Two Pharmaceutical Skin Care Creams for Xerotic Feet Among Persons with Diabetes
Introduction Diabetic foot-ulcers leads to decreased quality of life, risk of major amputation, and resource demanding health-care.
- Trial name
- NCT06427889
- Testing
- Canoderm, Oviderm, Decubal
- Where
- Sweden
- Volunteers
- 98 people
- Sponsor
- Malmö University