Clinical trials: Individual Psychiatric Disorder
Advanced Care Planning
A Portal-based Advance Care Planning Intervention Among Community-Dwelling Persons Living With Cognitive Impairment
The purpose of this research is to examine the feasibility of using a patient portal based advance care planning (ACP) tool to improve ACP discussions and documentation in persons living with cognitive impairment in outpatient…
- Trial name
- Portal-Voice (NCT06509373)
- Testing
- Advance Care Planning Tool - ACPVoice, Standard of Care for Advance Care Planning
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Wake Forest University Health Sciences
Dementia, Alzheimer Disease
Our Care Wishes - Dementia
This Our Care Wishes- Dementia pilot study is adapting an existing successful online advance care planning platform to the specific needs of persons living with dementia and shared decision-makers (SDMs) and testing the usability…
- Conditions
- Dementia, Alzheimer Disease, Memory Impairment
- Trial name
- NCT05033262
- Testing
- Our Memory Care Wishes
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
HIV/AIDS, Smoking Cessation
Learn to Quit-HIV Pilot Study
The study team will conduct a feasibility, acceptability, and preliminary efficacy trial comparing Learn to Quit-HIV (n=30) to an app based on U.S.
- Conditions
- HIV/AIDS, Smoking Cessation, Tobacco Use Disorder
- Trial name
- NCT04609514
- Testing
- Learn to Quit-HIV, QuitGuide, Nicotine patch
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Duke University
Bipolar Disorder
Efficacy and Safety of Galantamine for Improving Dysfunction in People With Bipolar Disorder
This study will examine whether extended release galantamine, a drug approved by the Food and Drug Administration to reduce cognitive impairments in people with Alzheimer's disease, can perform the same function in stable people…
- Trial name
- NCT00741598
- Testing
- Galantamine-ER
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Opioid Use Disorder, Pregnancy Related
Personally-Tailored Opioid-overdose and Medication for Opioid Use Disorder (MOUD) Education (TOME) for Pregnant and Postpartum Persons in MOUD
The primary objective of this study is to evaluate the ability of TOME to increase Medication for Opioid Use Disorder (MOUD) and opioid-overdose knowledge in pregnant and postpartum persons.
- Conditions
- Opioid Use Disorder, Pregnancy Related, Substance Use, Drug Abuse
- Trial name
- TOME (NCT06262347)
- Testing
- Personally-Tailored Opioid-overdose and Medication for opioid use disorder (MOUD) Education (TOME), Control
- Where
- 6 sites in United States
- Volunteers
- 131 people
- Sponsor
- T. John Winhusen, PhD
Hepatitis C, Medication Adherence
Intensive Models of HCV Care for Injection Drug Users
Injection drug users (IDUs) constitute 60% of the approximately 5 million people in the U.S. infected with hepatitis C virus (HCV). HCV treatment leading to sustained viral response (SVR) is associated with increased survival.
- Trial name
- NCT01857245
- Testing
- Intensive Models (mDOT and CGT) of HCV Care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Prisma Health-Upstate
PTSD
Prolonged Exposure (PE) for Post Traumatic Stress Disorder (PTSD): Telemedicine Versus In Person
The present proposal is to study whether Prolonged Exposure (PE) delivered via Telemedicine is as effective as PE delivered In Person for Operation Iraqi Freedom (OIF), Operation Enduring Freedom (OEF) Veterans and Veterans of…
- Trial name
- NCT01102764
- Testing
- Telemedicine, In Person
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- VA Office of Research and Development
Schizophrenia
Comparison of Aripiprazole and Risperidone for the Treatment of People With First-Episode Psychosis
This 52 week long study evaluates the effectiveness of aripiprazole versus risperidone in treating people with first-episode schizophrenia.
- Trial name
- NCT00320671
- Testing
- Aripiprazole, Risperidone
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Northwell Health
Schizophrenia
Effects of Intranasal Oxytocin on Satiety Signaling in People With Schizophrenia
The objective of this study is to test a single dose of intranasal oxytocin, compared to placebo, in a within subjects, crossover design, to see if oxytocin will improve satiety signaling (behaviorally and/or by self report)…
- Trial name
- NCT01614093
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Maryland, Baltimore
HIV/AIDS, Insomnia
Cognitive Behavioral Therapy to Treat Insomnia in Persons With HIV Infection
The goal of this preliminary study is to determine the efficacy of an internet-based treatment program for insomnia for HIV-infected persons.
- Trial name
- NCT03390114
- Testing
- SHUTi
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Advance Care Planning, Palliative Care
Palliative Care for Persons With ADRD and CI in SNF
Alzheimer's disease and related dementias (ADRD) are serious, life limiting illnesses with no known cure. Dementia is the fifth-leading cause of death in older adults and the majority of people with advanced dementia die in…
- Conditions
- Advance Care Planning, Palliative Care, Skilled Nursing Facility, Cognitive Impairment
- Trial name
- NCT05308004
- Testing
- Palliative Care Consultation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Maryland, Baltimore
Homelessness, Substance Abuse Disorders
Addiction Housing Case Management for Homeless Veterans
The study examined intensive case management for homeless Veterans in addiction treatment by integrating addiction/housing case managers (AHCM), operating from a Life Skills Training perspective, into an addiction specialty…
- Conditions
- Homelessness, Substance Abuse Disorders, Mental Disorders
- Trial name
- AHCM (NCT01346514)
- Testing
- Intensive Addiction/Housing Case Management, Housing Support Group
- Where
- United States
- Volunteers
- 181 people
- Sponsor
- VA Office of Research and Development
Mental Disorders
RCT Social Cognition Training and Therapeutic Alliance Focused Therapy for Persons With Severe Mental Illness
The study evaluates the effectiveness of the social cognition and interaction training (SCIT), in comparison to both therapeutic alliance focused therapy (TAFT) and treatment as usual (TAU) among persons with severe mental…
- Trial name
- NCT02380885
- Testing
- SCIT, TAFT
- Where
- 5 sites in Israel
- Volunteers
- 158 people
- Sponsor
- Bar-Ilan University, Israel
Schizophrenia and Disorders With Psychotic Features, Tobacco Use Disorder
Contingent Incentives Plus Bupropion for Smoking in People With Schizophrenia
There is a high prevalence of smoking among people with schizophrenia, and there are few smoking treatment programs for these smokers.
- Trial name
- NCT00136760
- Testing
- Bupropion, non-contingent reinforcement plus bupropion
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Brown University
Opioid Use, Opioid-use Disorder
Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder: Supplement to COMPUTE 2.0
This study integrates the Mental Health Research Network (MHRN) suicide risk models into Opioid Wizard, an electronic health record (EHR) clinical decision support (CDS) to identify and treat patients at high risk of opioid use…
- Conditions
- Opioid Use, Opioid-use Disorder, Suicide
- Trial name
- NCT04939727
- Testing
- OUD-CDS + Suicide Risk Model associated CDS
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- HealthPartners Institute
Mild Cognitive Impairment
Preventing Loss of Independence Through Exercise (PLIÉ) in Persons With Mild Cognitive Impairment (MCI)
Nearly 1 in 10 older Americans have dementia, which is a devastating condition that leads to a progressive loss of independence and functional status.
- Trial name
- MCI PLIE (NCT03526146)
- Testing
- Behavioral: Preventing Loss of Independence through Exercise (PLIE)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of California, San Francisco
Alzheimer Disease, Musculoskeletal Pain
At-Home Telehealth Yoga for Treating Chronic Pain in People With Alzheimer's Disease and Their Caregiver's
This feasibility study will evaluate yoga as a treatment for chronic pain in people living with Alzheimer's disease, and their Caregivers.
- Conditions
- Alzheimer Disease, Musculoskeletal Pain, Chronic Pain
- Trial name
- NCT04512040
- Testing
- At-Home Yoga
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Palo Alto Veterans Institute for Research
Dementia, Alzheimer's Disease
Magnesium L-Threonate for the Enhancement of Learning and Memory in People With Dementia
The purpose of this study is to examine the effects of supplementing Magnesium L-Threonate in people with mild to moderate dementia.
- Trial name
- NCT02210286
- Testing
- Magtein
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Stanford University