Clinical trials: Individualized PEEP
Cerebral Hemodynamics, Mechanical Ventilation Strategies
Cerebral Hemodynamic Effects of Individualized PEEP During Robotic Prostatectomy
This randomized clinical trial will compare two approaches to setting positive end-expiratory pressure (PEEP) during robot-assisted radical prostatectomy performed in the Trendelenburg position.
- Conditions
- Cerebral Hemodynamics, Mechanical Ventilation Strategies, Robotic Prostatectomy
- Trial name
- NCT07784010
- Testing
- Individualized PEEP Titration, Standard PEEP Group
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul University
Postoperative Complications, Mechanical Ventilation Complication
Individualized Selection of PEEP in Patients Affected by Expiratory Flow Limitation
The goal of this clinical trial is to compare different mechanical ventilation settings in Patients undergoing laparoscopic surgery and affected by Expiratory flow limitation.
- Trial name
- PEEP-EFL (NCT06215001)
- Testing
- Mechanical ventilation setting (Positive end-expiratory pressure) according to Expiratory Flow Limitation, Mechanical ventilation setting (Positive end-expiratory pressure) not according to Expiratory Flow Limitation
- Volunteers
- 1,536 people
- Sponsor
- Università degli Studi di Ferrara
Pulmonary Disease (COPD), Chronic Obstructive, Lung Resection Surgery
Effect of Individualized Positive End-expiratory Pressure (PEEP) in Patients Who Have an Intrinsic PEEP During One-lung Ventilation
This study investigates the effects of three extrinsic PEEP settings-5 cmH2O, 0 cmH2O, and an individualized PEEP (70% of the measured intrinsic PEEP)-on intrinsic PEEP and hemodynamic stability in patients with intrinsic PEEP…
- Trial name
- NCT07638176
- Testing
- PEEP0, PEEP5, PEEPi
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Samsung Medical Center
Respiratory Failure
Transpulmonary Assessment for Individualized Lung Optimization in Obese Patients
This protocol describes a randomized controlled feasibility vanguard study designed to investigate the implementation and effects of esophageal pressure-guided positive end-expiratory pressure (PEEP) titration in patients with…
- Trial name
- TAILOR-PEEP (NCT07359261)
- Testing
- Esophageal pressure-guided PEEP titration, Standard care PEEP management
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of Alberta
Pulmonary Atelectasis, Obesity, Morbid
Effects of Individualized PEEP Guided by Driving Pressure on Postoperative Atelectasis in Patients With Morbid Obesity
Atelectasis is a common complication in patients undergoing surgery under general anesthesia, particularly in obese patients. Postoperative atelectasis could last for more than 24h and contribute to a variety of other…
- Trial name
- NCT06181279
- Testing
- Individualized PEEP group, Fixed PEEP group
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Yongtao Sun
Laparoscopic Surgery, Pneumoperitoneum
Role of Individualized PEEP Vs Fixed PEEP in Mechanical Ventilation During Laparoscopic Surgeries
To compare the effects of Individualized positive end-expiratory pressure with recruitment maneuver on respiratory parameters and oxygenation in mechanical ventilation during laparoscopic surgeries with the fixed positive…
- Conditions
- Laparoscopic Surgery, Pneumoperitoneum, Positive End Expiratory Pressure (PEEP)
- Trial name
- NCT06929078
- Testing
- Protective lung ventilation methods with different positive end-expiratory pressure during Laparoscopic Surgeries
- Where
- Pakistan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Noor-Ul-Ain
Prostate Cancer
Effect of Optimized PEEP on Mechanical Ventilation During Robot Assisted Laparoscopic Prostatectomy
Steep trendelenburg posture or pneumoperitoneum for surgery causes ventilation problems during surgery, so finding a way to overcome is a challenging task for anesthesiologists.
- Trial name
- NCT05669443
- Testing
- conventional PEEP, optimized PEEP
- Where
- South Korea
- Volunteers
- 42 people
- Sponsor
- Gangnam Severance Hospital
ARDS
Incremental and Decremental PEEP Titration by Diverse Strategies in Subjects With ARDS: A Prospective Physiological Study
The investigators conducted a prospective physiological observation study on ARDS population, described their physiological and EIT indexes with various PEEP titration methods, and also compared and analyzed those indexes to…
- Trial name
- ARDS，PEEP (NCT06808438)
- Testing
- Esophageal pressure catheter
- Where
- China
- Volunteers
- 31 people
- Sponsor
- West China Hospital
Postoperative Atelectasis
Effect of Intraoperative Dynamic Compliance Guided Individualized Positive End-expiratory Pressure on Postoperative Atelectasis After Laparoscopic Bariatric Surgery
This study intends to explore the effect of dynamic compliance guided individualized positive end-expiratory pressure titration strategy on reducing the level of postoperative atelectasis in obese patient who have laparoscopic…
- Trial name
- NCT04169607
- Testing
- Dynamic compliance guided individualized positive end-expiratory pressure titration strategy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xuzhou Medical University
Postoperative Pulmonary Complications, Mechanical Ventilation
Driving Pressure-Guided Individualized PEEP Versus Standard PEEP: Effects on Postoperative Pulmonary Complications in Upper Abdominal Digestive Surgery
This randomized clinical trial compares two methods of setting positive end-expiratory pressure (PEEP) during general anesthesia in adults undergoing upper abdominal digestive surgery who are at moderate or high risk of…
- Trial name
- NCT07885124
- Testing
- Driving Pressure-Guided Individualized PEEP, Standard PEEP
- Where
- Tunisia
- Volunteers
- 210 people
- Sponsor
- Hopital Charles Nicolle
Peep Titration in Lung Protective Ventilation
Lung Protective Ventilation and Driving Pressure Guided PEEP Titration in CABG Surgery
Our aim in this study is to compare fixed and individualized PEEP (driving pressure guided ) application for intraoperative lung protective ventilation in patients undergoing on-pump CABG surgery.
- Trial name
- NCT07044089
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Lung Compliance
Individualized Positive End-expiratory Pressure Evaluation Using the Intratidal Compliance-volume Profile in Children
The investigators assess the changes in respiratory compliance according to different levels of positive end expiratory pressure (PEEP) in children under general anesthesia.
- Trial name
- NCT03533296
- Testing
- Positive end expiratory pressure (PEEP)
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Seoul National University Hospital
Respiratory Distress Syndrome, Adult
Pilot Study of Positive-End Expiratory Pressure in Acute Respiratory Distress Syndrome
Randomized controlled pilot trial in 70 patients with Acute Respiratory Distress Syndrome (ARDS) ventilated with low tidal volumes and limitation on airway pressure at 35 centimeters of water (cmH2O), to compare two different…
- Trial name
- PEEP-HUPA (NCT01119872)
- Testing
- Positive End-expiratory Pressure (PEEP)
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital Universitario Principe de Asturias
One-Lung Ventilation, Obesity
Individualized vs Low PEEP in One Lung Ventilation
The aim of the prospective crossover study is to investigate the effect of individualized positive end-expiratory pressure (PEEP) on measures of tissue oxygenation, compared with low PEEP.
- Conditions
- One-Lung Ventilation, Obesity, Lung Diseases
- Trial name
- NCT03569774
- Testing
- One-lung ventilation with individualized PEEP, One-lung ventilation with low PEEP
- Where
- United States
- Sponsor
- Dionne Peacher
Post Operative Cardiac Surgery, ARDS
PEEP Levels Selected by PEEP Titration and PEEP Levels Routinely Used in Post-operative Cardiac Patients With Hypoxemic Respiratory Failure
The purpose of this study is to: Compare PEEP level selected by individualized PEEP titration by electrical impedance tomography and PEEP level routinely used in post-operative cardiac patients with Hypoxemic Respiratory Failure…
- Conditions
- Post Operative Cardiac Surgery, ARDS, Hypoxemic Respiratory Failure
- Trial name
- NCT02056977
- Testing
- Titration, control
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- University of Sao Paulo General Hospital
Obesity, Postoperative Pulmonary Complications
Comparison of Standard Versus Dynamic Compliance-Guided Individualized PEEP in Obese Patients Undergoing Spinal Surgery
This study aims to compare standard positive end-expiratory pressure (PEEP) with dynamic compliance-guided individualized PEEP in obese patients undergoing elective spinal surgery under general anesthesia.
- Conditions
- Obesity, Postoperative Pulmonary Complications, Mechanical Ventilation
- Trial name
- NCT07388719
- Testing
- Standard PEEP
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Konya City Hospital
Recruitment Maneuver, Individualized PEEP
Optimal Ventilation Strategies in Laparoscopic Hysterectomy
The aim of this study was to investigate whether individualized PEEP application improves respiratory function and reduces the incidence of postoperative pulmonary complications (PPCs) in patients undergoing laparoscopic total…
- Conditions
- Recruitment Maneuver, Individualized PEEP, Total Hysterectomy, Postoperative Pulmonary Complications
- Trial name
- NCT07000448
- Testing
- Dynamic compliance guided individualized positive end-expiratory pressure titration strategy, standardized 5 PEEP
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
PostoperativePulmonaryComplications
A Multicenter Randomized Controlled Clinical Trial of the Impact of Minimally Invasive Abdominal Surgery Esophageal Pressure Monitoring Guided Individualized PEEP on Postoperative Pulmonary Complications in Obese Patients
The aim of this study is to compare the effect of individualized PEEP based on transmural lung pressure and fixed PEEP on postoperative pulmonary complications during laparoscopic or robotic abdominal surgery in obese patients.
- Trial name
- NCT06996288
- Testing
- Transpulmonary pressure-guided individualized PEEP
- Volunteers
- 180 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Obese Patients With Bariatric Surgery, Lung Ultrasound Score
Comparison Between Individualized PEEP Ventilation Guided by Driving Pressure and Conventional Lung Protective Strategy in Obese Patients Undergoing Laparoscopic Bariatric Surgery
this study to compare the ventilation in obese patients either using Driving pressure ventilation technique or conventional protective lung strategy all by using Lung ultrasound score
- Trial name
- NCT06950112
- Testing
- lung ultrasound
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mahmoud Gamal Ahmed Arakeeb
Postoperative Respiratory Complications
Individualized Intraoperative PEEP Following Alveolar Recruitment Maneuvres and Postoperative Respiratory Complications
Patients ASA I-III, undergoing laparoscopic abdominal surgery will be randomly assigned, into one of two groups, namely group C-PEEP , that will be the control group ; and group I-PEEP, where alveolar recruitment maneuvres will…
- Trial name
- NCT06600386
- Testing
- Alveolar recruitement, Standard PEEP
- Where
- Greece
- Volunteers
- 69 people
- Sponsor
- Asklepieion Voulas General Hospital