Clinical trials: Indocyanine Green
Choroidal Melanoma
Ranibizumab as Adjuvant Therapy for the Treatment of Choroidal Melanoma (Cohort 2)
Ranibizumab has proven to be of benefit to improve the perfusion in the retina of patients with Choroidal Melanoma. The investigators consider that higher doses of Ranibizumab can help reduce the number of laser treatments that…
- Trial name
- NCT01251978
- Testing
- Ranibizumab 2 mg, 0.5 mg Ranibizumab
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- New England Retina Associates
Hepatocellular Carcinoma
Electromagnetic Tracking and Optical Imaging With ICG for Hepatic Biopsies
Background: Liver cancer is the sixth most common cancer worldwide. Diagnosing liver cancer usually requires a liver sample. Getting the best sample helps determine whether cancer is present and what kind of cancer it is.
- Trial name
- NCT04258566
- Testing
- Optical Molecular Imaging (OMI), Indocyanine Green (ICG), Electromagnetic Tracking
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
High Risk Polyposis Syndrome, Distal Colonic Lesions
Indocyanine Green Fluorescent Molecular Imaging of the Gastrointestinal Tract
Standard white light endoscopy involves the passage of a thin, flexible camera into the colon from the anus. Although standard white light endoscopy can detect most polyps and precancerous areas in the gastrointestinal tract and…
- Conditions
- High Risk Polyposis Syndrome, Distal Colonic Lesions, Colorectal Polyps
- Trial name
- NCT01112514
- Testing
- indocyanine green
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Massachusetts General Hospital
Stage I Breast Cancer, Stage II Breast Cancer
Comparison of Use of Indocyanine Green and 99mTc-labeled Radiotracer for Axillary Lymphatic Mapping in Patients With Breast Cancer
This clinical trial will enroll up to 130 adult women with a confirmed diagnosis of clinical stage 1 or 2 breast cancer who are undergoing breast cancer surgery with lumpectomy or mastectomy and planned axillary sentinel node…
- Trial name
- NCT02419807
- Testing
- Indocyanine Green Solution, Technetium Tc-99m Sulfur Colloid, Lymphoscintigraphy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Case Comprehensive Cancer Center
Trauma Injury
ICG Fluorescence Imaging in Lower Extremity Amputation Patients
This is a non-randomized prospective study of 30 patients scheduled to undergo lower extremity amputation (below the knee, through the knee or above the knee) evaluating bone perfusion and viability using indocyanine green (ICG)…
- Trial name
- NCT04250558
- Testing
- Lower Extremity Amputation
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Breast Neoplasms
Study Assessing The Interest of Indocyanine Green Fluorescence Imaging With Radioisotope Method For Sentinel Lymph Node Biopsy in Patients With Breast Cancer
The sentinel node has a fundamental role in the management of early breast cancer. Currently, the double detection of blue and radioisotope is recommended.
- Trial name
- FLUOTECH (NCT02279108)
- Testing
- indocyanine green, isotope
- Where
- France
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Breast Cancer
Pilot Indocyanine Green Imaging for Mapping of Arm Draining Lymphatics & Nodes in Breast Cancer
The purpose of this study is to determine if Indocyanine Green (IC-GREEN) is comparable to isosulfan blue (IS-BLUE) in the identification of arm lymphatics and arm-draining nodes during nodal staging procedures in breast cancer.
- Trial name
- NCT01771666
- Testing
- SPY Elite Imaging, Indocyanine Green, Isosulfan blue
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Stanford University
Recurrent Melanoma
Lymph Node Mapping Using Indocyanine Green Solution in Diagnosing Patients With Malignant Melanoma
This clinical trial compares and contrasts lymph node mapping using indocyanine green (IC-GREEN), isosulfan blue (ISB), and TSC and Lymphoscintigraphy with 99-technetium (99Tc) sulfur colloid (TSC).
- Trial name
- NCT01898403
- Testing
- Indocyanine green solution, Isosulfan blue (ISB), Lymphoscintigraphy with 99-technetium (99Tc) sulfur colloid (TSC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Endometrial Cancer
Concurrent Use Lymphoseek & Indocyanine Green in Sentinel Lymph Node Detection in Endometrial Cancer
The goal of this study is to (i) improve detection of sentinel nodes and (ii) reduce additional surgical dissection that is needed in case a sentinel lymph node cannot be detected.
- Trial name
- NCT04511026
- Testing
- Lymphoseek, Single Photon Emission Computed Tomography (SPECT), Indocyanine Green (ICG)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Stanford University
Cholecystitis, Hepatocellular Carcinoma
Low Dose ICG for Biliary Tract and Tumor Imaging
Near-infrared fluorescence (NIRF) imaging after an intravenous injection of indocyanine green (ICG) allows for the intraoperative identification of liver anatomy.
- Conditions
- Cholecystitis, Hepatocellular Carcinoma, Liver Metastases
- Trial name
- ICG (NCT04942665)
- Testing
- Indocyanine green, PINPOINT Endoscopic Fluorescence
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Florida
Lymphedema
Effect of Exercise on Indocyanine Green (ICG) Lymphography Imaging
Indocyanine Green (ICG) lymphography is a relatively new imaging technique that allows for quick visualization of superficial lymph flow in real-time, without radiation exposure.
- Trial name
- NCT03584633
- Testing
- Indocyanine Green
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Iowa
Skull Base Neoplasms
ICG Use in Angiography for Nasoseptal Flap Harvest
This is a feasibility study in which indocyanine green (ICG) will be administered during routine expanded endonasal approach (EEA) for cranial base pathologies in which a nasoseptal flap harvest will be necessary.
- Trial name
- ICG (NCT02117310)
- Testing
- indocyanine green
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Ohio State University
Laparoscopic Cholecystectomy
Clinical Trial for the Optimization of Indocyanine Green Administration in NIRF-C During L.Cholecystectomy.
Laparoscopic cholecystectomy is one of the most performed surgical procedures worldwide. One of its most serious complications is injury to the main bile duct, with an incidence of less than 1%.
- Trial name
- DOTIG (NCT05419947)
- Testing
- VERDYE powder for solution for injection 25 mg
- Where
- 2 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Endometrial Cancer
Lymph Node Mapping in Patients With Endometrial Cancer
This clinical trial studies lymph node mapping in patients with endometrial cancer. Lymph node mapping may allow for limited removal of lymph nodes in as part of endometrial cancer staging and treatment.
- Trial name
- NCT01818739
- Testing
- sentinel lymph node detection, indocyanine green solution, isosulfan blue
- Where
- 2 sites in United States
- Volunteers
- 204 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Fractures, Comminuted, Surgical Wound Dehiscence
Application of Indocyanine Green Angiography for Closed Operative Calcaneus Fractures
Researchers in the Orthopaedic surgery department at LSU Medical Center-Shreveport hope to learn if patterns of blood-flow around the incision site of patients undergoing surgery for heel-bone fractures can help predict whether…
- Conditions
- Fractures, Comminuted, Surgical Wound Dehiscence, Necrosis
- Trial name
- NCT01693484
- Testing
- ICG (Indocyanine Green)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Pediatric Patients With Solid Tumors
A Study Comparing Green Fluorescent Dye and Radioactive Dye for Sentinel Lymph Node Biopsy in Pediatric Cancers
This study is being done in patients that have tumors to find out how well sentinel lymph nodes (SLNs) can be found with a special dye called indocyanine green (ICG).
- Trial name
- NCT02910726
- Testing
- Sentinel Lymph Node Biopsy, indocyanine green (ICG)
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Burns
Indocyanine Green (ICG) and SPY Imaging for Assessment of Burn Healing
Three patients were recruited for assessment of ICG fluorescence in burns.
- Trial name
- NCT02766244
- Testing
- ICG/SPY, Antibiotic Ointment
- Volunteers
- 3 people
- Sponsor
- Texas Tech University Health Sciences Center
Endometrial Cancer
Detection of SLN in Patients With Endometrial Cancer Undergoing Robotic Assisted Staging: Comparison of ISB and ICG
The investigators hypothesis is that if sensitivity and specificity are found to be significantly higher than the current reports with Technesium-99 and ISB colorimetric dye, SLN biopsies might allow omission of full…
- Trial name
- NCT02068820
- Testing
- ISB dye and standard white light imaging, ICG dye and FireFly fluorescence imaging
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- AdventHealth
Melanoma, Sentinel Node
Infrared Lymphangiography as a Method of Sentinel Node Identification
The initial treatment for most people with melanoma involves wide excision of the skin and sentinel node biopsy. As with other cancers, the status of the sentinel node provides important prognostic information to the patient and…
- Trial name
- SPY-SN (NCT02057393)
- Testing
- Indocyanine green, Technetium99, Methylene blue
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Milton S. Hershey Medical Center
Colorectal Cancer
Lymphatic Mapping for Sentinel Node Identification and Analysis
The main objective of this study is to determine whether the first (sentinel) lymph nodes in the drainage pathway of colonic tumour can be detected at the time of surgery using a new technique.
- Trial name
- NCT01662752
- Testing
- Indocyanine green
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Imperial College London