Clinical trials: Indoor Air Quality
Healthcare Associated Infection
Monitors to Improve Indoor Carbon Dioxide (CO2) Concentrations in the Hospital
Ventilation with fresh outdoor air has recently gained considerable attention as a means to reduce the potential risk of indoor aerosol transmission of respiratory pathogens such as severe acute respiratory syndrome coronavirus 2…
- Trial name
- MICH (NCT04770597)
- Testing
- Aranet4 Home CO2 monitor
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Imelda Hospital, Bonheiden
COPD (Chronic Obstructive Pulmonary Disease), Acute Exacerbation of COPD
The Impact of Indoor Environmental Quality on Symptoms in Patients With Chronic Obstructive Pulmonary Disease
This prospective, monocenter pilot study will investigate the relationship between indoor environmental quality (including air quality, lighting, noise, and thermal conditions), wearable-derived health insights, and…
- Trial name
- COPD-AIR (NCT07799896)
- Testing
- Wearable mobile device, Indoor environmental quality sensor, CAT Questionnaire
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Ziekenhuis Oost-Limburg
Chronic Obstructive Pulmonary Disease (COPD)
Clinical Trial of Air Cleaners to Improve Indoor Air Quality and COPD Health
Objectives (include all primary and secondary objectives) Specific Aim #1: To determine whether an air cleaner intervention to improve home air quality will improve respiratory symptoms, quality of life, lung function and reduce…
- Trial name
- NCT02236858
- Testing
- HEPA Air Cleaner
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- Johns Hopkins University
Pollution; Exposure
Milwaukee Day Cares Indoor Air Quality Assessment and Educational Response Study
This CTSI pilot study will assess for benefit of a community health worker or nursing student taught green cleaning curriculum (developed by the local asthma coalition) provided to Milwaukee County day care staff.
- Trial name
- NCT03675009
- Testing
- Educational Programming
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06579950)
- Testing
- Cool roof
- Where
- 5 sites in Burkina Faso, Fiji and 3 more
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Faecal Contamination of Household Drinking Water (Environmental Outcome)
Evaluation of a Project to Distribute Water Filters and Cookstoves in Western Rwanda
DelAgua Health and Development, Manna Energy and the Rwanda Ministry of Health are collaborating on a project financed by carbon credits that will distribute household-based water filters and high-efficiency cook stoves to…
- Trial name
- NCT01882777
- Testing
- Household drinking water filters and cookstoves
- Where
- Rwanda
- Volunteers
- 566 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico
Ambient air temperatures in Mexico have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06834893)
- Testing
- Cool roof
- Where
- Mexico
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Environmental Exposure
Real-Life Passive Exposure Assessment of IQOS
This study is a non-interventional observational study designed to assess the impact of passive exposure to IQOS environmental tobacco aerosol in Non-Smokers in a real-life restaurant setting.
- Trial name
- NCT03550989
- Testing
- Non-Exposure Event, Exposure Event
- Where
- Japan
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Asthma Control, Pulmonary Function
Asthma Intervention With Residential Ventilation and Air Cleaner (AIRVAC) Study
The primary goal of this study is to investigate the comparative long-term (i.e., 1-year) effectiveness of energy recovery ventilators (ERVs) and portable air cleaners (PACs) in reducing indoor air pollutants and mold levels and…
- Conditions
- Asthma Control, Pulmonary Function, Quality of Life, Stress
- Trial name
- NCT07196436
- Testing
- Energy Recovery Ventilator, Portable Air Cleaner
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas at Arlington
Subjective Discomfort, General Mucosal Irritation
Controlled Human Exposure to Indoor Air, Dust and Ozone
The aim of the study is to provide information which may help to improve the quality of the life of persons exposed to indoor environments in Danish dwellings.
- Conditions
- Subjective Discomfort, General Mucosal Irritation, Acute Changes in Respiratory Outcomes, Acute Changes in Cardiovascular Outcomes
- Trial name
- XDOZ (NCT02017782)
- Testing
- Dust, Ozone, Dust and Ozone
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Tobacco Use, Smoking
CSD200902: Assessment of Indoor Air Quality for a Heated Tobacco Product With Four Non-Combusted Cigarette Variants in an Environmental Testing Chamber
This is a single-center, open-label, parallel-cohort study to measure and compare the levels of selected secondhand smoke (SHS) constituents of a heated tobacco product (HTP) against combustible cigarettes (CC) after ad libitum…
- Conditions
- Tobacco Use, Smoking, Tobacco Smoking
- Trial name
- NCT05363254
- Testing
- Marlboro Gold Box, Newport Box, Non-combusted cigarette variant 42001401
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
SARS-CoV2 Infection, Influenza Viral Infections
Reducing Respiratory Virus Transmission in Bangladeshi Classrooms
This study will test if affordable air cleaning devices (box fans with a filter attached and/or ultraviolet light lamps) installed in classrooms can reduce the number of viral respiratory illnesses schoolchildren experience.
- Conditions
- SARS-CoV2 Infection, Influenza Viral Infections, Respiratory Viral Infection
- Trial name
- NCT06247059
- Testing
- Box Fan, UV Germicidal Irradiation Lamp Unit, Combined: Box Fan and UV Germicidal Irradiation Lamp Units
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Focus of Study is to Assess Filter and Stove Use and Efficacy in Reducing Exposure to Waterborne and Airborne Pathogens
Evaluation of a Project to Distribute Water Filters and Cook Stoves in Western Rwanda--Phase 1B
DelAgua Health and Development, Manna Energy and the Rwanda Ministry of Health are collaborating on a project financed by carbon credits that will distribute household-based water filters and high-efficiency cook stoves to…
- Trial name
- NCT01998282
- Where
- Rwanda
- Volunteers
- 1,035 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health in Niue
Ambient air temperatures in the Pacific have broken record highs in 2024. Solutions are needed to build heat resilience in communities and adapt to increasing heat from climate change.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06570993)
- Testing
- Cool roof
- Where
- Niue
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Pediatric Asthma
Humidity Asthma Interventions for Low Socioeconomic Status Children
The goal of this intervention study is to assess the effectiveness of low-cost humidity and mold reduction interventions in the home for reducing pediatric asthma.
- Trial name
- INHALE (NCT07453667)
- Testing
- Healthy home intervention
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Case Western Reserve University
Cardiovascular Diseases, Blood Pressure
Evaluation of a Novel Indoor Air Pollution Intervention Among Older Adults
Particulate matter air pollution is the leading environmental risk factor of cardiovascular disease and is increasing in the Western United States due to more frequent and severe wildfires.
- Conditions
- Cardiovascular Diseases, Blood Pressure, Glycated Hemoglobin (HbA1c), Cholesterol
- Trial name
- NCT07539987
- Testing
- Air Improvement and Real-time Monitoring for Wellness through Interactive Strategies and Education (AIRWISE), Portable Air Cleaner (PAC) Control
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- University of Montana
Primary Ciliary Dyskinesia (PCD), Cystic Fibrosis (CF)
Clean Air for Rare MUcociliary Clearance dIsorders
The goal of this clinical trial is to learn whether using a high efficiency particulate air (HEPA) air purifier can improve respiratory health in children and adults with Cystic Fibrosis (CF) or Primary Ciliary Dyskinesia (PCD).
- Trial name
- CARMUCI (NCT07417267)
- Testing
- Intervention configuration - air purifiers equipped with HEPA and three other filters for efficient particle filtration
- Where
- Cyprus
- Volunteers
- 62 people
- Sponsor
- University of Cyprus
Respiratory Tract Diseases, Cardiovascular Diseases
ASPIRE Health Tulare County
The goal of this clinical trial is to compare indoor air quality and health in people exposed to air pollution, including possible exposure to wildfire smoke.
- Trial name
- ASPIREHealth (NCT05944770)
- Testing
- DIY portable air cleaner with a highly effective filter
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Cognition
Indoor Air Quality Monitoring and Impact on Children's Health
This study aims at understanding the relation between indoor air quality in schools, including both chemical and microbiological determinants, and cognition in children by gathering data across different parts of Europe
- Trial name
- LEARN (NCT06197477)
- Testing
- OurAir SQ 1750 - Mobile Air Purification System for indoor
- Where
- Belgium
- Volunteers
- 900 people
- Sponsor
- Hasselt University
Airway Morbidity, Cognitive and Attention Disorders and Disturbances
Short-term Health Benefits of Using Fresh Air Filtration System in Classroom
A randomized crossover trial will be conducted in 90 primary school children in 3 classrooms in Shanghai, China. The effects of fresh air ventilation/filtration system, fresh air ventilation system with no filtration and natual…
- Conditions
- Airway Morbidity, Cognitive and Attention Disorders and Disturbances, Oxidative Stress
- Trial name
- NCT03788330
- Testing
- Fresh air system with filtration
- Where
- China
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Fudan University