Clinical trials: Induced Vaginal Delivery, active
Perineal Trauma, Postpartum Pain
RELIEVE Study- Platelet-Rich Plasma to Reduce Postpartum Pain After Perineal Tears or Episiotomy
Perineal tears and episiotomies are common after vaginal birth and may cause persistent pain, impaired wound healing, pain during sexual activity, and concerns about genital appearance.
- Conditions
- Perineal Trauma, Postpartum Pain, Episiotomy, Perineal Laceration
- Trial name
- RELIEVE (NCT07727213)
- Testing
- Autologous Non-Activated Platelet-Rich Plasma, Saline (0.9%, sterile, for infusion)
- Where
- Switzerland
- Volunteers
- 160 people
- Sponsor
- University Hospital, Geneva
Premature Rupture of Fetal Membranes, Labor, Induced
PGE2 Followed by Oxytocin vs Oxytocin in Term PROM (POXY-PROM)
This study is being done to learn more about the best way to start labor for pregnant women whose water breaks at term before labor begins, a condition called term prelabor rupture of membranes (term PROM).
- Conditions
- Premature Rupture of Fetal Membranes, Labor, Induced, Cervical Ripening
- Trial name
- POXY-PROM (NCT07366359)
- Testing
- Sequential Induction: Dinoprostone Followed by Oxytocin, Immediate Oxytocin Induction
- Where
- Vietnam
- Volunteers
- 450 people
- Sponsor
- National Hospital of Obstetrics and Gynecology
Bronchopulmonary Dysplasia
The Role of Volatile Organic Compounds (VOCs), Airway Mucins and the Microbiome in the Early Prediction of Bronchopulmonary Dysplasia (BPD)
Bronchopulmonary dysplasia (BPD), the most common respiratory complication of extremely preterm birth, significantly impacts healthcare with high morbidity and mortality rates.
- Trial name
- INFANCY (NCT06342752)
- Testing
- Breath test, Throat swabs, Placental samples
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Nulliparous Women Who Scheduled for Labor Induction, Pregnancy
Ripening Approaches for Prompt Induction and Delivery - Sequential Versus Concurrent Dilapan-S and Misoprostol to Achieve Vaginal Delivery (RAPID-DS)
The purpose of this study is to compare the effectiveness of sequential versus combined multimodal cervical ripening strategies to achieve vaginal delivery within 24 hours among nulliparous patients with singleton, vertex…
- Trial name
- RAPID-DS (NCT07717502)
- Testing
- Sequential Cervical Ripening, Inpatient Combined Cervical Ripening
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Ochsner Health System
Labor, Induced, Term Pregnancy
Comparison of Vaginal PGE2 (Dinoprostone) and Vaginal Misoprostol for Induction of Labour in Primigravid Term Pregnancy
This randomized controlled trial was conducted to compare vaginal misoprostol and vaginal PGE2 (dinoprostone) for induction of labour in primigravid women with term pregnancy.
- Conditions
- Labor, Induced, Term Pregnancy, Cervical Ripening
- Trial name
- NCT07559812
- Testing
- Misoprostol, Dinoprostone 3 mg
- Where
- Pakistan
- Volunteers
- 240 people
- Sponsor
- Mayo Hospital Lahore
Induced; Birth
Outcome of Concurrent Versus Sequential Method of Induction of Labour in Term Pregnancy
This randomized controlled trial will compare two methods of induction of labour in women with term pregnancy: concurrent use of a Foley catheter and PGE2 vaginal pessary versus sequential use of the two methods.
- Trial name
- NCT07821099
- Testing
- Foley Catheter, PGE2 Vaginal Pessary
- Where
- Pakistan
- Volunteers
- 128 people
- Sponsor
- Khyber Medical University Peshawar