Clinical trials: Induction of General Anesthesia
Electroconvulsive Therapy, Anesthesia, General
Induction Agents in ECT: Effects on Seizure Duration, Quality, and Recovery
The goal of this observational study is to determine if there are any differences in seizure duration, seizure quality, and recovery time associated with the utilize of different anesthetic induction agents in patients undergoing…
- Trial name
- NCT07596095
- Testing
- Propofol group, Thiopental, Ketamine (0.5 mg/kg)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Postoperative Complications
Colloid Infusion for Optimal Outcomes In Non-cardiac Surgery (COIN Trial)
Hypotension is associated with postoperative complications. Preoperative fluid infusion can effectively prevent post-induction hypotension of general anesthesia.
- Trial name
- COIN (NCT05728645)
- Testing
- Hydroxyethyl Starch 130/0.4 and Electrolyte injection of 5ml/kg, Multiple Electrolytes injection of 5 ml/kg
- Where
- China
- Volunteers
- 2,022 people
- Sponsor
- Xijing Hospital
Hemodynamic Instability, Anesthesia, General
Hemodynamics During Induction of General Anesthesia After Prophylactic Ephedrine, Phenylephrine or Norepinephrine.
In this trial the investigators want to examine if there is any difference in hemodynamic stability when giving equipotent prophylactic injections of ephedrine 0,1 mg/kg, phenylephrine 1 microg/kg, norepinephrine 0,1 microg/kg or…
- Conditions
- Hemodynamic Instability, Anesthesia, General, Anesthesia, Intravenous
- Trial name
- VH (NCT03864094)
- Testing
- Ephedrine, Phenylephrine, Norepinephrine
- Where
- Norway
- Volunteers
- 128 people
- Sponsor
- Helse Fonna
General Anesthesia, Ventilator-Induced Lung Injuries
Prevention of Postoperative Respiratory Complications
Given the huge number of patients mechanically ventilated during general anaesthesia, optimizing alveolar recruitment by limiting pulmonary and systemic aggression is a key objective for further progress in perioperative patient…
- Conditions
- General Anesthesia, Ventilator-Induced Lung Injuries, Postoperative Respiratory Complications
- Trial name
- RAMAGE (NCT06899295)
- Testing
- Continuous measurement of esophageal pressure Peso (cmH2O), Measurement of impedance variation with each respiratory cycle (EIT), Z in ohm, Measurement of regional respiratory compliance (EIT), Ohm/cmH2O
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypotension on Induction
PoCUS Guided Fluids to Prevent Post-induction Hypotension
Hypotension is a common side-effect of general anesthesia induction, and is related to adverse outcomes, including a significantly increased risk of one-year mortality.
- Trial name
- HIPO (NCT05424510)
- Testing
- Ringer's Lactate, IV line
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Mount Sinai Hospital, Canada
Anesthesia, Sedation
EEG Signal Correlates During Anesthesia and Sedation in Adults and Children
This prospective, multicenter, non-interventional observational study investigates the correlates between electroencephalographic (EEG) signals and pharmacological/clinical parameters during general anesthesia and procedural…
- Conditions
- Anesthesia, Sedation, Consciousness Monitors
- Trial name
- SPECTRALADUPED (NCT07460414)
- Where
- 2 sites in France
- Volunteers
- 330 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia Outcomes, Anesthesia Complication
Does Style of Pre-sedation Instructions Improve Patient Outcomes in Ambulatory Anesthesia for Oral and Maxillofacial Surgery?
This randomized controlled trial aims to evaluate the impact of a brief guided visualization exercise on anesthesia-related outcomes in oral and maxillofacial surgery in patients scheduled for ambulatory anesthesia in the oral…
- Conditions
- Anesthesia Outcomes, Anesthesia Complication, Anesthesia and Procedure Related Time Intervals, Anesthesia Recovery Period
- Trial name
- NCT06768021
- Testing
- Guided visualization and standardized pre-sedation instructions, Standardized pre-sedation instructions only
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Alameda Health System
Induction and Maintenance of General Anesthesia
A Study to Evaluate the Efficacy and Safety of HSK3486 in the Induction of General Anesthesia
This is a multi-center, randomized, single-blind, propofol injectable emulsion parallel-controlled Phase III clinical study. A total of patients undergoing elective surgery are intended to be enrolled and randomly assigned to…
- Trial name
- NCT04511728
- Testing
- HSK3486, Propofol
- Where
- China
- Volunteers
- 129 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.
Drug Safety
Efficacy and Safety of Fospropofol in Adult Laparoscopic Surgery: A Clinical Trial
This protocol is a clinical study of fospropofol disodium for general anesthesia in adults undergoing laparoscope-assisted abdominal surgery.
- Trial name
- NCT06573489
- Testing
- Fospropofol, Propofol
- Where
- China
- Volunteers
- 373 people
- Sponsor
- Hui Xu
Diabetes
Effects of Remimazolam and Propofol on Anesthesia Induction
The patients with diabetes who underwent laparoscopic cholecystectomy in the general surgery department of the Second Hospital of Shanxi Medical University were selected.
- Trial name
- NCT06009055
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Zheng Guo
Anesthesia Induction
EcoAnaesthesia Facemask Versus Standard Facemask During Anesthesia Induction
This study will evaluate the efficiency of the EcoAnesthesia mask and its advantages over the standard facemask used in our practice.
- Trial name
- NCT01103947
- Testing
- EcoAnaesthesia facemask first, Portex Adult (Standard) facemask first, Portex Adult (Standard) facemask second
- Where
- United States
- Sponsor
- University of Louisville
Labor Pain, Cesarean Delivery Regional Anesthesia Induction
Neuraxial Ultrasound Device Study
The aim of the study is to develop a device that can eliminate failed neuraxial placements in challenging patients.The study will attempt to improve safety and efficacy of neuraxial anesthesia with high precision real-time needle…
- Trial name
- NCT06281249
- Testing
- Ultrasound placement device
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Anesthesia
EEG Studies of Sevoflurane-Induced General Anesthesia
The investigators are performing this research study to find out how and where the anesthetic drugs sevoflurane and ketamine act in the brain.
- Trial name
- NCT03503578
- Testing
- Sevoflurane, Ketamine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Post Induction Hypotension
Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery
Video-assisted thoracoscopic surgery (VATS) is widely used in thoracic surgery due to small incisions, low stress response, and high patient tolerance.
- Trial name
- NCT07374458
- Testing
- Esketamine, Bilateral Lower Limb Elevation
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University