Clinical trials: Induction of Labour
Pregnancy, Induced Labor
Adjuvant Oxytocin for Preinduction Ripening With a Foley catheter--a Clinical Trial
The transcervical Foley catheter (TFC) is a proven and effective mode of cervical ripening. It is common practice to use TFC with simultaneous low-dose oxytocin under the assumption that the combination results in a more…
- Conditions
- Pregnancy, Induced Labor, Cervical Ripening
- Trial name
- NCT00468520
- Testing
- low dose oxytocin
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Columbia University
Labor Pain
Effect of Music in Labor in Women Who Underwent Induction of Labor
Women's experience of pain during labor varies greatly, and pain control is a major concern for obstetricians. Several methods have been studied for pain management for women in labor, including drug and non-drug interventions…
- Trial name
- NCT04662424
- Testing
- music in labor
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Federico II University
Pregnancy
Relevance of Ultrasound Screening for Foetal Macrosomia
Management of fetal macrosomia is based on a suspicion of macrosomia (no certainty before birth). This management is an artificial induction of labour for an earlier delivery and therefore a lower fetal weight gain.
- Trial name
- USmacro (NCT04443205)
- Testing
- Data record
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- CHU de Reims
Cervical Ripening, Labor, Induced
A Randomized Study on Comparing the Efficacy of Foley Catheter and Extraamniotic Saline Infusion for Labor Induction
Our purpose was to compare the efficacy and safety of Foley catheter with oxytocin and extraamniotic saline infusion with oxytocin for induction of labor requiring cervical ripening.
- Trial name
- NCT00366951
- Testing
- Foley catheter only, Extraamniotic saline infusion
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rush University Medical Center
Labor Pain
Labor Induction and Pain Relief With Paracetamol Versus Placebo
Single-blind study conducted on 2 randomly selected groups of pregnant women carrying a single fetus (from week 37 onward). One group will receive paracetamol 1 gr I.V.
- Trial name
- NCT05097950
- Testing
- Administration of 1 gr paracetamol I.V
- Where
- Israel
- Volunteers
- 141 people
- Sponsor
- Western Galilee Hospital-Nahariya
Cervical Ripening
Comparing Methods for Balloon Catheter Inserting: View Guided (Speculum) Versus Manual Guided at Cervical Examination
Induction of labor is a common obstetric procedure. Foley catheter is recommended by WHO for cervical ripening. Insertion is typically speculum guided but digital insertion has been reported to be faster, better tolerated and…
- Trial name
- NCT05253690
- Testing
- balloon catheter insertion approach for labor induction
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Induction of Labor, Cervical Ripening
Combined Nipple Stimulation and Foley Balloon for Cervical Ripening
Labor induction rates have increased substantially worldwide, and successful cervical ripening remains a key determinant of induction outcomes.
- Trial name
- NCT07317674
- Testing
- Foley balloon catheter with nipple stimulation, Mechanical cervical ripening with Foley catheter
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Failed Induction of Labor
A Comparison of Transcervical Foley Catheter and Prostaglandins for Induction of Labor at Term
The purpose of this study is to assess the effectiveness and safety of transcervical foley catheter as compared to prostaglandins for preinduction cervical ripening and labor induction in term nulliparous women with unfavorable…
- Trial name
- NCT01317862
- Testing
- Transcervical foley catheter, Prostaglandins
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Seoul National University Hospital
Neurodevelopmental Disorders
5-Year Follow-up of Children and Mother After Expectant Management Versus Induction of Labor in Low-risk Nulliparous Women at 39 Weeks of Gestation
In France, the rate of labor induction has markedly increased in recent years, partly following the ARRIVE trial suggesting short-term benefits of elective induction at 39 weeks in low-risk nulliparous women.
- Trial name
- FAMILY-FA (NCT07330336)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 4,200 people
- Sponsor
- University Hospital, Bordeaux
Labor Induction
Early Amniotomy Versus Delayed Amniotomy Following Foley Catheter Ripening in Nulliparous Labor Induction
Amniotomy (breaking the bag of water) is commonly used in the induction of labor. However, the timing is highly variable. The purpose of this study is to determine if first time mothers undergoing induction of labor with a Foley…
- Trial name
- NCT03039036
- Testing
- Amniotomy, Foley Catheter, Misoprostol
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Northwestern University
Induction of Labour, Labour, Induced
Misoprostol Labour Induction Study
Labour induction is a frequent obstetric intervention (~20%). Prostaglandins (PGs) are effective agents, but gastrointestinal (GI) intolerance has limited use to non-oral routes.
- Trial name
- NCT03489928
- Testing
- Oral Misoprostol, Vaginal Misoprostol, Dinoprostone
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- David Young
Labor, Induced
Sublingual Misoprostol for Induction of Labor
The purpose of this study is to compare effectiveness and safety of a sublingual misoprostol 12,5 mcg with vaginal misoprostol 25 mcg for induction of labour with an alive and term fetus.
- Trial name
- SUBMISO (NCT01406392)
- Testing
- Misoprostol 25mcg, Sublingual Misoprostol
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Labor, Induced, Cervical Ripening
Labor Induction With a Combined Method (Pharmacologic and Mechanical): Randomized Controlled Trial
Labor induction is a common pregnancy procedure worldwide. Both mechanical and pharmacologic agents are used for induction of labor. These agents reduce the incidence of cesarean delivery in women undergoing induction.
- Trial name
- NCT03928600
- Testing
- Cervical Foley combined with Misoprostol, Dinoprostone 10mg insert OR, Misoprostol
- Where
- Portugal
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Prelabour Rupture of Membranes at Term
A Pilot RCT on the Management of Term Prelabour Rupture of Membranes
This is a pilot study that will eventually result in a main randomised controlled trial that will look at what management is associated with a higher rate of normal birth and a lower rate of chorioamnionitis (maternal infection)…
- Trial name
- NCT02872883
- Testing
- Expectant management, Minimal Vaginal examinations (only when necessary), Active management
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Central Lancashire
Induction of Labor Affected Fetus / Newborn, Rupture of Membranes Prior to Onset of Labor
Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes
The study aims to evaluate and assess the effectiveness and safety of vaginal administration of isosorbide mono nitrate (IMN) to induce cervical ripening and shorten the interval time between induction and delivery in women…
- Trial name
- NCT03665779
- Testing
- isosorbide mononitrate
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- ahmed nagy shaker ramadan
Cervical Ripening and Induction of Labor
Comparison Between Vaginal Misoprostol Gel and Oral Misoprostol Solution in Induction of Labor
The goal of this clinical trial is to study the efficacy of vaginal versus oral misoprostol solution in cervical ripening for induction of labor.
- Trial name
- NCT06874049
- Testing
- Vaginal misoprostol, Oral misoprostol solution (OMS)
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hagar Muhammad Abdulfattah Muhammad
Labor; Forced or Induced, Affecting Fetus or Newborn
The Comparison of Oxytocin Induced Labor and Cook Balloon Induced Labor
Currently, the study about intervention on the induced abortion at trimester is so little. So, the investigators want to compare the safety and effectiveness of different induced labor.
- Trial name
- NCT02202083
- Testing
- Cook Balloon
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- West China Second University Hospital
Labour Induction
Impact of Early Versus Late Amniotomy on Labour Induction in Nulliparous Women After Vaginal Misoprostol
Investigation the effect of timing of amniotomy (early versus delayed) after vaginal misoprostol in induced labor. Condition: induction of labour intervention: eary versus late amniotomy on labour induction after vaginal…
- Trial name
- RCT (NCT04514770)
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Induction of Labor
Induction of Labor by Oral Misoprostol Solution
AIM: To evaluate effectiveness and safety of titrated oral misoprostol solution (OMS) in comparison with static-dose oral misoprostol solution for induction of labor at term.
- Trial name
- OMS (NCT04891679)
- Testing
- Oral misoprostol solution (OMS)
- Where
- India
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Labour, Induced
Comparative Bioavailability Study of Two Misoprostol Formulations
The purpose of this study is to compare pharmacokinetics of two formulations of misoprostol following single dose administration in adult women being given misoprostol for cervical ripening and induction of labour.
- Trial name
- NCT02516631
- Testing
- Angusta™, Cytotec®
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Region Skane