Clinical trials: Induction of Ovulation
Female Infertility
Progesterone on the Day of Ovulation Induction is Associated With Pregnancy Outcome
Progesterone levels measured in blood/serum of patients on the day of ovulation induction following controlled ovarian stimulation for in vitro fertilization may be associated with pregnancy outcome.
- Trial name
- ProgBBN (NCT01426152)
- Where
- Germany
- Volunteers
- 2,555 people
- Sponsor
- Bollmann Bruckner Noss
Assisted Reproductive Techniques, Reproductive Technology, Assisted
PERgoveriS In Stratified Treatment for Assisted Reproductive Technique
This is a multicenter, multi-national, randomized, open-label comparative trial. After screening, the subjects will start down-regulation treatment on Day 21-22 of the cycle.
- Trial name
- PERSIST (NCT01297465)
- Testing
- Gonal-f®, Pergoveris®, Recombinant human chorionic gonadotropin (r-hCG)
- Where
- 23 sites in Denmark, Finland and 9 more
- Volunteers
- 202 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Female Urogenital Diseases
Evaluation of Time Interval Between Ovulation Trigger With Triptorelin Acetate and Oocyte Retrieval
The aim of this study is to determine what is the best time interval between GnRH agonist (triptorelin acetate) ovulation induction allowing for the higher number of mature oocytes (MII) collected in IVF cycles.
- Trial name
- TIMING (NCT02244151)
- Testing
- Decapeptyl® diario, Decapeptyl® daily
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Ovulation Induction
AS900672-Enriched in Ovulation Induction
This is a Phase 2, interventional, multi-center, randomized, assessor-blind, active-comparator, dose-finding study to evaluate a new investigational long-acting follicle stimulating hormone (FSH) in oligo-anovulatory women…
- Trial name
- NCT00553514
- Testing
- AS900672-Enriched 10 microgram (mcg), AS900672-Enriched 20 mcg, AS900672-Enriched 30 mcg
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Sterility
Comparative Assessment of the Clinical Utility of Ovarian Stimulation With Menotropin Versus Menotropin Plus GnRH Antagonist
To assess the effectiveness of protocols of ovarian hyperstimulation combining urinary gonadotrophins + GnRH antagonist vs urinary gonadotrophins, to achieve clinical pregnancy in females undergoing intrauterine insemination.
- Trial name
- PROMENIA (NCT01331733)
- Testing
- hMG-HP, hMG + GnRH antagonist
- Where
- 7 sites in Spain
- Volunteers
- 131 people
- Sponsor
- Ferring Pharmaceuticals
Infertility
A Phase 3b Study to Evaluate Subject Satisfaction With Follitropin Alfa Injection in Oligoanovulatory Infertile Women Undergoing Ovulation Induction
This is a prospective, open-label, multicenter, trial evaluating subject satisfaction and efficacy with follitropin alfa injection applied by Pen device compared with the subject's previous experience with injectable…
- Trial name
- NCT00230815
- Testing
- Follitropin alfa injected by Pen device, Recombinant Human Choriogonadotropin (r-hCG)
- Volunteers
- 62 people
- Sponsor
- EMD Serono
Infertility
Gametes Transfer vs. Embryo Transfer for Women Undergoing Assisted Reproductive Techniques: a Randomized Controlled Trial
Background: The cost for the treatment of infertility are limiting for the health care access, particularly if we consider that the success rate per cycle is approximately 35%.
- Trial name
- NCT01839136
- Testing
- Intrauterine transfer of gametes, Intrauterine transfer of embryos
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Infertility
36 Versus 42 Hour Time Interval From Ovulation to Intrauterine Insemination
The purpose of this study is to prove that a higher clinical pregnancy rate can be achieved with a 42 to 44 hour time interval between ovulation trigger and intrauterine insemination than a 36 to 38 hour time interval in…
- Trial name
- NCT02210611
- Testing
- Intrauterine Insemination 36 hours, Intrauterine Insemination 42 hours
- Where
- Israel
- Volunteers
- 71 people
- Sponsor
- HaEmek Medical Center, Israel
Infertility
Comparison of Clomiphene Citrate and Gonadotropins in Ovulation Induction Cycles
The purpose of the present study is to analyse prospectively if highly purified hMG compared with increased dose of clomiphene citrate has different outcomes in folliculogenesis in ovulation induction cycles.
- Trial name
- cc versus FSH (NCT00835744)
- Testing
- clomiphene citrate, gonadotropins
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universitair Ziekenhuis Brussel
Subfertility, Pregnancy
A RCT Comparing Spontaneous Natural Cycles and Human Chorionic Gonadotrophin-induced Natural Cycles in FET
This is a randomized controlled trial on the comparison of the ongoing pregnancy rate in frozen-thawed embryo transfer cycles with spontaneous ovulation and hCG-induced natural cycles.
- Trial name
- NCT02197208
- Testing
- Daily monitoring of LH and E2, hCG induced natural cycle, ultrasound
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 300 people
- Sponsor
- The University of Hong Kong
Breast Cancer Female
Combining Interventions of Fertility Preservation to Mitigate Fertility Loss After Breast Cancer
This clinical prospective randomised controlled trial will evaluate the impact of an ovarian biopsy on the oocyte yield after controlled ovarian stimulation before chemotherapy in view of breast cancer.
- Trial name
- Coimbra (NCT04586686)
- Testing
- Ovarian biopsy via laparoscopy, Transvaginal oocyte retrieval
- Where
- 2 sites in Belgium
- Volunteers
- 41 people
- Sponsor
- Universitair Ziekenhuis Brussel
Ovulation Induction
A Phase 2 Trial to Evaluate if Corifollitropin Alfa (Org 36286), Followed by a Low Daily Dose of hCG or Recombinant FSH Can Induce Monofollicular Growth in Women With WHO Group II Anovulatory Infertility (P05693)
The primary objective of this trial is to evaluate whether a corifollitropin alfa (Org 36286) regimen applying a single or repeated dose of corifollitropin alfa followed by a low daily dose of Human Chorion Gonadotropin (hCG) or…
- Trial name
- NCT00697255
- Testing
- corifollitropin alfa, recombinant Follicle Stimulating Hormone (recFSH), human Chorion Gonadotropin (hCG)
- Volunteers
- 8 people
- Sponsor
- Organon and Co