Clinical trials: Induction of Ovulation
Ovulation Induction, Polycystic Ovary Syndrome
Effect of Adding Isoflavonoids to Clomiphene Citrate for Ovulation Induction in Women With Polycystic Ovary Syndrome
This prospective, randomized clinical trial double blinded study, has been carried on 160 infertile patients seeking pregnancy in Gynecology and Obstetrics Department, Zagazig University Hospitals during the period from January…
- Trial name
- NCT04610957
- Testing
- Rosafem (FEMININE FORMULA)
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- FAlbasri
IVF Poor Responders
Optimizing Ovulation Induction in the Poor Responder
The purpose of this randomized controlled trial is to compare the efficacy and effect of luteal estradiol and combined oral contraceptive pills (COPC) on follicle recruitment and synchrony in a poor responder population.
- Trial name
- NCT01200537
- Testing
- Estradiol, Oral Contraceptive Pills (OCP)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
Infertility
Luteal Support and Intrauterine Insemination (IUI) With Clomiphene Citrate
The purpose of this study is to assess the effect of luteal phase supplement (LPS) on pregnancy rate in IUI cycles stimulated with clomiphene citrate.
- Trial name
- NCT01046708
- Testing
- micronized progesterone
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Multifollicular Stimulation
An Observational Study to Compare the Dose of Gonal-fTM FbM Prescribed by the Doctor With the Recommendation of the Dose Calculator Consort and to Evaluate the Ease of Use of Pre-filled Pen of Gonal-fTM FbM Pen
This is a prospective, observational and multicentric study to compare the Gonal-f FbM (filled by mass) dose prescribed by the doctor with the Gonal-f FbM dose determined by the CONSORT (Consistency in r-FSH Starting doses for…
- Trial name
- NCT01080729
- Testing
- Recombinant-follicle stimulating hormone (r-FSH)
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Fertility Disorders
Injection Free IVF
Investigation of Natural Cycle In vitro Fertilisation (NC-IVF) treatment with ovulation induction with a nasal GnRH agonist instead of regular NC-IVF treatment with subcutaneous application of hCG with the objective of increasing…
- Trial name
- NCT04850261
- Testing
- hCG Injection, Nafarelin nasal spray
- Volunteers
- healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
in Vitro Fertilization, Ovulation Induction
Trial Comparing Start Stimulation of Recombinant Follicle Stimulating Hormone (rFSH) on Cycle Day 2 Versus Cycle Day 5 in In Vitro Fertilization (IVF)
Background of the study: Milder stimulation protocols have the advantage of being less expensive and more patient-friendly. Moreover, recent evidence suggests that mild stimulation protocols lead to lower embryo aneuploidy rates…
- Trial name
- LITE (NCT00823472)
- Testing
- Mild stimulation
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Comparison Between Two Ovulation Induction Therapies and LOD on Clinical Outcomes in CC-Resistant PCOS Women
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder affecting 4-8% of reproductive-aged women and is a leading cause of infertility due to oligo-anovulation (1).
- Trial name
- NCT06486870
- Testing
- Gonadotropin, Letrozole, laparoscopic ovarian drilling
- Where
- Egypt
- Volunteers
- 183 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
Combined Metformin and Clomiphene Citrate (CC) or Laparoscopic Ovarian Diathermy for Women With CC Resistant Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to compare and determine the efficacy of combined metformin and Clomiphene citrate administration to that of laparoscopic ovarian diathermy (LOD) in infertile women with Polycystic ovary syndrome…
- Trial name
- NCT00969631
- Testing
- metformin HCl (Cidophage®; CID,Cairo, Egypt), CC (Clomid®; Global Napi Pharmaceuticals,Cairo, Egypt),Cairo, Egypt), Laparoscopic ovarian diathermy (LOD)
- Where
- Egypt
- Volunteers
- 282 people
- Sponsor
- Mansoura University
Polycystic Ovary Syndrome
Combined Chromium With Letrozole Versus Letrozole Only in Induction of Ovulation in Patients With Polycystic Ovary Syndrome
Combined letrozole with chromium versus letrozole only in induction of ovulation in polycystic ovary syndrome
- Trial name
- NCT05765305
- Testing
- Letrozole with chromium
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infertility, Polycystic Ovarian Syndrome
Letrozole Versus Clomifene Citrate for Ovulation Induction
The primary aim of the study is to assess the efficacy of letrozole as an ovulation induction agent and to test the hypothesis that letrozole will generate better pregnancy rates with fewer multiple pregnancies and higher live…
- Trial name
- NCT00478504
- Testing
- Letrozole, Clomifene citrate
- Where
- United Kingdom
- Volunteers
- 159 people
- Sponsor
- University of Nottingham
Luteal Phase Insufficiency
Early Luteal Phase Progesterone Kinetics After hCG-Induced Ovulation in Modified Natural Cycle
This pilot study evaluates how progesterone levels change after hCG-triggered ovulation in modified natural cycles. Forty women preparing for frozen embryo transfer will have blood tests over 6 days to monitor hormone levels.
- Trial name
- CineP4 (NCT07028710)
- Testing
- hCG
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Infertility, Ovarian Hyperstimulation Syndrome
Monitoring the Early Follicular Phase With Androstenedione in Low-dose Step-up Ovulation Induction in High Responders
This study aims to predefine the threshold FSH doses during the early follicular phases in low- dose step-up ovulation induction cycles used to treat anticipated high responders by monitoring total testosterone and…
- Trial name
- NCT02329483
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Neonatal SEPSIS, Perinatal Mortality
Outcomes in Spontaneous and ART Twin Pregnancies
During the last decades, assisted reproductive technique has been transformed from a miracle to real and has become widely used for treatment human infertility. this was associated with increased the rate of twin pregnancies
- Conditions
- Neonatal SEPSIS, Perinatal Mortality, Maternal Morbidity
- Trial name
- NCT03590483
- Where
- Iraq
- Volunteers
- 200 people
- Sponsor
- Hawler Medical University
PCOS, Myo-inositol-resistance
Myo-inositol Plus Alpha-lactalbumin in PCOS Myo-inositol-resistant Patients
The investigator's aim is to evaluate if the combination of myo-inositol and alpha-lactalbumin can overcome the resistance to myo-inositol in PCOS patients
- Trial name
- NCT03667443
- Testing
- Myo-inositol + folic a. + α-lactalbumin, Myo-inositol + folic a.
- Where
- Bulgaria
- Volunteers
- 50 people
- Sponsor
- Lo.Li.Pharma s.r.l
Coenzyme q10
Coenzyme q 10 and Fertility Outcome in Women With Clomiphene Resistant PCOS
The study evaluates the effect of coenzyme q 10 on ovulation and subsequent pregnancy in women with polycystic ovarian syndrome.
- Trial name
- NCT04302532
- Testing
- Coenzyme Q10, clomiphene citrate
- Where
- Pakistan
- Volunteers
- 149 people
- Sponsor
- Karachi Medical and Dental College
Polycystic Ovary Syndrome
Coenzyme Q10 and Clomiphene Citrate (CC) for Ovulation Induction in Polycystic Ovary Syndrome
Objective of the study was to evaluate the effect of combination of oral Coenzyme Q10 (CoQ10), with clomiphene citrate (CC) for ovulation induction in CC-resistant polycystic ovary syndrome (PCOS).In a prospective controlled…
- Trial name
- NCT01910766
- Testing
- Coenzyme Q10, clomiphene citrate
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Polycystic Ovary
Clomiphene Citrate Stair-Step Protocol
A RCT will be conducted to compare the traditional clomiphene citrate regimens for ovulation induction with the stair-step protocol.
- Trial name
- NCT03178500
- Testing
- Clomiphene Citrate 50mg
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Polycystic Ovary Syndrome, Infertility
Effect of Progestin-Induced Withdrawal Bleed on Ovulation Induction Cycles With Clomiphene Citrate
Women with polycystic ovary syndrome (PCOS) can suffer from infertility because they do not produce an egg each month, resulting in irregular periods.
- Trial name
- NCT01966575
- Testing
- Progestin
- Where
- Canada
- Sponsor
- University of British Columbia
Poor Response to Ovulation Induction
Effect of LH Supplementation on the Endometrial Gene Expression Profile in Poor Ovarian Responders
This is a prospective randomized open-label cross-over study. Poor responder patients will undergo two ovarian stimulation cycles.
- Trial name
- NCT05405686
- Testing
- Lutropin alfa, Follitropin alfa, Endometrial biopsy
- Sponsor
- CRG UZ Brussel
Infertility Poly Cystic Ovary
Letrozole Step-up Protocol for Ovulation Induction in Infertile Women With PCOS
the aim of the study is to compare between the step-up and conventional protocols in ovulation induction in infertile women with PCOS
- Trial name
- NCT03181919
- Testing
- Letrozole
- Volunteers
- 90 people
- Sponsor
- Benha University