Clinical trials: Infant Colic, open to volunteers
Osteopathy, PreTerm Neonate
The Effect of Cranial Osteopathy Intervention in Preterm Babies
There are planing to have 2 groups of premature born cases. Each group will include 15 cases. Participants are need to be 28-37 weeks born and no older than post term 6 weeks. All cases are going to be evaluated.
- Conditions
- Osteopathy, PreTerm Neonate, Sensory Profiles, Colic
- Trial name
- NCT06967870
- Testing
- Osteopathic intervention, Home based exercise education
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Infantile Colic, Gastroesophageal Reflux (GER)
BioAmicus Complete for Functional Gastrointestinal Symptoms in Infants Aged 0 to 24 Months
Infants often experience functional gastrointestinal symptoms (e.g., colic, excessive gas, regurgitation, constipation, or loose stools) that distress families and may reflect an imbalance of the gut microbiome.
- Conditions
- Infantile Colic, Gastroesophageal Reflux (GER), Functional Constipation, Functional Diarrhea
- Trial name
- CTBE2503 (NCT07148583)
- Testing
- BioAmicus Complete, Usual Care (No Probiotic)
- Where
- Vietnam
- Volunteers
- 110 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Cytomegalovirus Infections
QuantiFERON-CMV Test in a Prediction for Colic Cytomegalovirus Reactivation During Ulcerative Colitis
CytoMegaloVirus (CMV) infection impairs evolution of Ulcerative Colitis (UC) leading to more severe and resistant to immunosuppressive therapies flare-up.
- Trial name
- RECOHFERRON (NCT04030676)
- Testing
- Biopsies, Blood samples
- Where
- 2 sites in France
- Volunteers
- 196 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Renal Colic, Acupuncture, Ear
Ear Pressure Points Plus Pain Meds for Faster Kidney Stone Pain Relief
Title: Can Ear Acupressure Help Relieve Kidney Stone Pain Faster When Combined with Painkillers? Purpose: This study tests whether adding ear acupressure to standard painkillers (NSAIDs) helps adults with kidney stone pain feel…
- Trial name
- NCT06978816
- Testing
- Non-Steroidal anti-inflammatory drugs (NSAIDS), Auricular Acupoint Embedding
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Gao Xiaofeng
Functional Gastrointestinal Disorders, Gastroesophageal Reflux
Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.
The goal of this observational study is to learn about the prevalence and characteristics of functional gastrointestinal disorders (FGID) in at risk infants (former preterm infants and those with birth asphyxia) during the first…
- Conditions
- Functional Gastrointestinal Disorders, Gastroesophageal Reflux, Constipation - Functional, Diarrhea
- Trial name
- FUSID (NCT06031025)
- Testing
- Questionnaire, clinical examination
- Where
- Italy
- Volunteers
- 71 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Infant Colic, Gut Microbiota
Effect of a Dietary Supplement vs Low-dosage Product on Infant Gastrointestinal Discomfort and Colics
The goal of this clinical trial is to verify whether a food supplement is effective in treating infantile colic of infants aged between 21 days and 9 months and the colonization ability of the gut microbiota by measuring faecal…
- Trial name
- DISIC (NCT07017244)
- Testing
- Verum, Active comparator
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Renal Colic, Kidney Stones, Urolithiasis, Hypocitraturia
Relief Efficacy of Lidocaine Versus Morphine for Acute Renal Colic in the Emergency Department
The opioid epidemic continues to be a major public health crisis in the United States. According to the Center for Disease Control, approximately 8 million Americans reported misusing prescription opioids in 2023, with over 5…
- Conditions
- Renal Colic, Kidney Stones, Urolithiasis, Hypocitraturia, Opioid Use During Medical Care
- Trial name
- RELIEF-RC (NCT07536594)
- Testing
- Lidocaine, Morphine 0,1 mg/kg
- Volunteers
- 250 people
- Sponsor
- Loma Linda University
Renal Colic
Comparative Efficacy of IV Dexamethasone vs. Nebulized Terbutaline for Renal Colic Pain in the ED
Adult patients (18-55 years of age) with clinical diagnosis of acute renal colic (sudden sharp colic flank pain with or without radiation to genitalia or groin and with or without urinary symptoms) who had pain score of 5 or more…
- Trial name
- NCT06980727
- Testing
- Terbutaline 2.5 mg, Dexamethasone
- Where
- Tunisia
- Volunteers
- 500 people
- Sponsor
- University of Monastir
Cholecystectomy, Gallbladder
EUS-Guided Gallbladder Drainage Versus Conservative Management in Patients Unfit for Surgery After a Biliary Event Without Cholecystitis. DRECON Study
Cholecystectomy is considered the standard definitive treatment after an acute biliary event (biliary colic, acute pancreatitis, cholangitis, or choledocholithiasis).
- Conditions
- Cholecystectomy, Gallbladder, Endoscopic Ultrasound (EUS), Cholelithiasis
- Trial name
- DRECON (NCT07655778)
- Testing
- EUS-guided gallbladder drainage (EUS-GBD), Conservative management (CM)
- Volunteers
- 110 people
- Sponsor
- Hospital Mutua de Terrassa
Renal Colic, Kidney Stones, Urolithiasis, Hypocitraturia
The Use of AR / VR in Patients Presenting to the ED With Renal Colic
Utilization of VR / AR Calming as an adjunct to pharmacologic pain management for Renal Colic in Emergency Department Patients
- Trial name
- NCT07070401
- Testing
- Commercial AR/VR Headset with Calming App, Pharmacologic Standard of Care Alone
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Community Medical Center, Toms River, NJ
Rectal Cancer, Colon Cancer
Contribution of Preserving the Superior Left Colic Artery to the Vascularization of the Descending Colon Prior to Colorectal Anastomosis During Left-Sided or Rectal Resections for Colorectal or Ovarian Cancer. (Revascularisation Colique)
Colorectal cancers and ovarian cancers are respectively the 2nd and 5th cause of cancer mortality in France. Surgical resection is a crucial step in the therapeutic management of colorectal cancers.
- Conditions
- Rectal Cancer, Colon Cancer, Ovarian Cancer
- Trial name
- NCT07098182
- Testing
- Clamping and restauration of arterial blood of the inferior mesenteric artery
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Healthy, Healthy Nutrition
The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial
The goal of The BEGIN Study, a randomized controlled double-blinded intervention trial, is to learn if probiotics, with Bifidobacterium longum subspecies infantis Bifin02 (B.
- Trial name
- BEGIN (NCT06452199)
- Testing
- B. infantis
- Where
- 2 sites in Denmark
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Colon Anastomosis
Flexagon Plus OTOLoc Colon Anastomosis in Patients Undergoing Surgery
The primary objective of this trial is to investigate the safety and effectiveness of the Flexagon SFM system plus OTOLoc when used to create a Ileo-colic and Colo-colonic anastomoses in participants undergoing colon surgery.
- Trial name
- FOCUS (NCT06915818)
- Testing
- Ileo-colic and colo-colonic Anastomosis with Flexagon SFM and OTOLoc
- Where
- 2 sites in Chile, India
- Volunteers
- 65 people
- Sponsor
- GI Windows, Inc.
Infantile Colic
The Effect of Probiotics in Infantile Colic
Academic, independent, non-commercial, multicenter study sponsored by the Department of Translational Medical Sciences (DISMET), University of Naples Federico II.
- Trial name
- CSUB0214 (NCT07894445)
- Testing
- Probiotic: L. reuteri DSM 17938 + BG-R46, total 2 × 10⁸ CFU/day
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Federico II University
Renal Colic
Analgesic Efficacy of Transcutaneous Electrical Nerve Stimulation and Dexketoprofen in Renal Colic
The aim of this study was to compare the analgesic efficacy of transcutaneous electrical nerve stimulation (TENS) and dexketoprofen trometamol in patients presenting to the emergency department due to renal colic.
- Trial name
- NCT07176572
- Testing
- TENS, Dexketoprofen Trometamol
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Adiyaman University Research Hospital
Massage Effect
Vimala Massage Infantile Colic, Sleep and Development Levels
Objective: The effect of Vimala massage applied by parents on infantile colic, sleep and developmental levels of infants will be investigated.
- Trial name
- VIMCOLSLEEP (NCT06993701)
- Testing
- Vimala Massage Training for Fathers, Control Intervention, Vimala Massage Training for Mothers
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Biliary Colic
Study on the Immediate Analgesic Effect of Yanglingquan Acupoint Treatment for Biliary Colic
Guided by traditional meridian and acupoint theory, conducting standardized, large-sample, multicenter randomized controlled trials (RCTs) to evaluate the clinical efficacy of pattern differentiation and meridian-based acupoint…
- Trial name
- NCT07194655
- Testing
- Acupuncture at the Yanglingquan point, Acupuncture at the Xiabai Point, Acupuncture at non-meridian points
- Volunteers
- 248 people
- Sponsor
- First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Anastomotic Leak, Colon Cancer
Leakage Rate of Ileo-COlic Sutured Anastomosis After Right Hemicolectomy
The primary aim of the study is to show that the ileo-colic anastomosis leakage rate until the first 30 days after surgery using MonoPlus® suture material for anastomosis construction after right hemicolectomy is not inferior to…
- Conditions
- Anastomotic Leak, Colon Cancer, Right Hemicolectomy
- Trial name
- LICOSARH (NCT07132970)
- Testing
- Monoplus Suture Material
- Where
- 4 sites in Germany
- Volunteers
- 249 people
- Sponsor
- Aesculap AG
Colic, Infantile, Milk Allergy, Cow's
Validation Of A Parent Administered Symptom Score For Unsettled Infants (Every Baby is UnIQue)
It's common for infants to be unsettled, especially in the first few months of life. While this is often normal, persistent symptoms can be stressful for families.
- Conditions
- Colic, Infantile, Milk Allergy, Cow's, Gastro Oesophageal Reflux Disease, Atopic Dermatitis (Eczema)
- Trial name
- NCT07121062
- Testing
- Online parent administered questionnaire
- Where
- United Kingdom
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Renal Colic
Oral NSAI Versus Acetaminophen or Placebo as a Discharge Treatment of Non Complicated Renal Colics
Treatment with NSAI in renal colics has not been well investigated and there is no clear recommendations regarding this subject.
- Trial name
- NAP-RC (NCT05722782)
- Testing
- Piroxicam, Acetaminophen
- Where
- Tunisia
- Volunteers
- 500 people
- Sponsor
- University of Monastir