Clinical trials: Infant Development, open to volunteers
Language Development, Language Development Disorders
Cortical Tracking of Speech in the First Year of Life
The goal of this observational study is to investigate early neural mechanisms underlying the processing of spoken language, specifically the phenomenon of cortical tracking, and to determine whether these mechanisms can serve as…
- Conditions
- Language Development, Language Development Disorders, Infant Development, Infant Developmental Assessment
- Trial name
- NCT07531706
- Testing
- Electrophysiological recording, Behavioral Assessment
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Preterm, Parent-Child Relations
Sensory Optimization of the Hospital Environment
The long-term goal of this project is to improve the health and well-being of preterm infants and their parents. Although there is evidence to support positive multisensory interventions in the NICU, these interventions are often…
- Conditions
- Preterm, Parent-Child Relations, Parents, Development, Infant
- Trial name
- SOOTHE (NCT05230199)
- Testing
- SENSE multisensory program, Monitored standard of care
- Where
- United States
- Volunteers
- 215 people
- Sponsor
- University of Southern California
Healthy Infants
Probiotic for Infants
The BABIES II study is a single-center, randomized, double-blinded, placebo-controlled study in newborns with an 8½ months intervention period from 14 days of age to 9 months of age followed by a 3-months short-term follow-up…
- Trial name
- BABIES II (NCT07054216)
- Testing
- Probiotic
- Where
- 2 sites in Denmark
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Child Development, Infant Development
Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants
This study will test the hypothesis that in preterm infants a caregiver-implemented early developmental intervention (EDI) using finger puppets to develop joint attention and encourage interactive communication with routine EDI…
- Conditions
- Child Development, Infant Development, Infant, Premature, Diseases
- Trial name
- IMPACT (NCT06335524)
- Testing
- Finger puppet, Bookworm reading intervention training and routine EDI care.
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- University of Alabama at Birmingham
Vestibular Disorder
Vestibular Function and Motor Development in Small Children
Infants and toddlers with and without vestibular impairment will be tested blinded by pediatric physiotherapist with different age adequate motor scales in order to find out pathological motor patterns specifically associated to…
- Trial name
- NCT07079488
- Testing
- Motor proficiency scales
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Healthy Infants
HMOs on Infant Gut Microbiota Modulation and Development of the Immune System in Healthy Infants
The goal of this clinical trial is to learn how a mixture of human milk oligosaccharides impacts the development of the infant microbiota, the immune maturation and how the interaction between the microbiota and immune maturation…
- Trial name
- BELIEF (NCT06631937)
- Testing
- Human Milk Oligosaccharides
- Where
- 2 sites in Denmark
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Language Delay, Language Development
Combined Oral Motor Stimulation and Language on Preterm Infant Feeding
This is a randomized controlled trial to study an oromotor stimulation in combination with a reading curriculum in the NICU among preterm infants using oral muscle exercises, Language Environment Analysis (LENA) recordings…
- Conditions
- Language Delay, Language Development, Feeding; Difficult, Newborn, Mother-Infant Interaction
- Trial name
- NCT05861531
- Testing
- Oromotor stimulation, Reading curriculum, LENA recording
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Iodine Deficiency, Nutrition Poor
Effects of Maternal Multiple Micronutrient Supplementation During Lactation on Child Development in Ethiopia
The goal of this clinical trial is to learn about the effects of iodine-containing multiple micronutrient supplements provided to breastfeeding mothers who live in settings with mild iodine deficiency.
- Conditions
- Iodine Deficiency, Nutrition Poor, Development, Infant, Breastfeeding
- Trial name
- EMECHAT (NCT05901766)
- Testing
- UNIMMAP Multiple Micronutrient Supplement
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Brown University
Microbial Colonization
Preterm Infant Intestinal Microbiota Development and Maternal Fecal Transplant
The goal of this clinical trial is to study if a oral maternal fecal transplant given to a premature infant born by cesarean section (CS) is safe.
- Trial name
- PREFLOR (NCT06227845)
- Testing
- Fecal microbiota transplant
- Where
- Finland
- Volunteers
- 36 people
- Sponsor
- Otto Helve
Development Delay, Motor Skills Disorders
Effect of a Telerehabilitation-Supported, Family-Centered Early Intervention Program on Neurodevelopmental and Parental Outcomes in Infants at Mild-to-Moderate Risk
The goal of this pilot randomized controlled trial is to learn whether a family-centered early intervention program, delivered remotely to parents and carried out at home, can support the development of infants who were treated…
- Conditions
- Development Delay, Motor Skills Disorders, Neurodevelomental Disorders, High Risk Infant
- Trial name
- NCT07878819
- Testing
- Remote Family-Centered Early Intervention Program, Standard Information and Routine Follow-up
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bengisu Boz Gürboğa
Confirmed Diagnosis of Cystic Fibrosis
Impact of Early Lung Physiology, Viral Infections and the Microbiota on the Development and Progression of Lung Disease in Children With Cystic Fibrosis
This study collects data on microbiological factors and lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess their interaction on the lung growth and lung development of infants and children with…
- Trial name
- SCILD (NCT04026360)
- Testing
- no intervention
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Autism, Autism Spectrum Disorder
Milieu Teaching-AV: Adaptation of Milieu Teaching That Encourages Looking to the Mouth
This project will look at Milieu Teaching (i.e., a language intervention) that encourages looking to audiovisual speech cues (Milieu Teaching-AV) for infants with autistic older siblings (Baby Sibs), who are highly likely be…
- Conditions
- Autism, Autism Spectrum Disorder, Autism, Susceptibility to, 6
- Trial name
- MilieuTeach-AV (NCT07494513)
- Testing
- Milieu Teaching-AV, Milieu Teaching-NoAV
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Father Flanagan's Boys' Home
Neurodevelopmental Disorders, Developmental Delay
Development of Motility and Cognition in Infants
PILKE study uses wearables for assessing motor development in infants in order to define functional growth trajectories in the normal infants and infants at risk of neurological compromise.
- Conditions
- Neurodevelopmental Disorders, Developmental Delay, Development, Infant, Child Development
- Trial name
- PILKE (NCT05527080)
- Testing
- physiotherapy, brace
- Where
- Finland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Obstructive Sleep Apnea, Down Syndrome (Trisomy 21)
Oro-myofunctional Characteristics and Obstructive Sleep Apnea in Infants With Down Syndrome
Obstructive Sleep Apnea (OSA) is characterised by repetitive collapse of the upper airway during sleep, inducing breathing disturbances that can result in oxygen desaturation and frequent arousals.
- Trial name
- OMF21 (NCT07195253)
- Testing
- Polysomnography (PSG) to explore OSA, Oro-myo-functional clinical evaluation, Sleep Disturbance Scale for Children
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Risky Baby, Premature Birth of Newborn
Synchronous vs. Asynchronous Telerehabilitation for High-Risk Infants
Premature birth, low birth weight, and a history of neonatal intensive care history are significant risk factors associated with long-term neurodevelopmental adverse outcomes in infants.
- Conditions
- Risky Baby, Premature Birth of Newborn, Motor Delay
- Trial name
- NCT07499843
- Testing
- Synchronous Telerehabilitation Group, Asynchronous Telerehabilitation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Biruni University
Developmental Dysplasia of Hip
Improving Neonatal Hip Screening With Artificial Intelligence
The goal of this trial is to pilot a portable ultrasound device that uses artificial intelligence to screen for hip dysplasia. Researchers will gather data to understand the feasibility of performing a larger trial in birthing…
- Trial name
- NCT07794644
- Testing
- Artificial intelligence augmented ultrasound
- Volunteers
- 100 people
- Sponsor
- Murdoch Childrens Research Institute
Depression - Major Depressive Disorder
Development of Attentional Biases for Affective Cues in Infants of Mothers With Depression
The goal of this study is to examine attentional biases for facial displays of emotion as a mechanism of risk in infants of mothers with postpartum major depression, and the potential role of infant arousal in the development of…
- Trial name
- NCT06835855
- Testing
- Passive Viewing Task, Interaction Task
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Binghamton University
Preterm Birth, Preeclampsia
The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health
The 'Standard of Care Plus' ('PLUS') model in the ROOT Study consists of analyzing select micronutrient and gene variants of pregnant females to construct trimester-specific and personalized nutrition and lifestyle…
- Conditions
- Preterm Birth, Preeclampsia, Gestational Diabetes Mellitus (GDM), Small for Gestational Age (SGA)
- Trial name
- ROOT (NCT07559773)
- Testing
- 'Standard of Care PLUS'
- Volunteers
- 500 people
- Sponsor
- GrowBaby Life Project
Sleep, Psychological Distress
The Development and Evaluation of Sleep Intervention for Perinatal Family
Background: Sleep disruptions and disturbances are highly prevalent among new mothers and fathers and negatively affect their mental health and infant development outcomes.
- Conditions
- Sleep, Psychological Distress, Perinatal Problems
- Trial name
- NCT06487650
- Testing
- sleep intervention, Control group
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Bronchopulmonary Dysplasia (BPD), Mortality Prediction
Chloride Imbalance in Preterm Infants
In adults and children low or high blood chloride levels are linked to the risk of death. The aim of this observational study is to determine whether there is a relationship between low or high blood chloride levels and the risk…
- Conditions
- Bronchopulmonary Dysplasia (BPD), Mortality Prediction, Chloride Disorder
- Trial name
- NCT06940856
- Testing
- Incomplete response, Complete response, Bad response
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital