Clinical trials: Infant Development, open to volunteers
DSD, CHH
Minipuberty in Infants Born With Potential Hypogonadism Hypogonadotrope
Disorders of sex development (DSD) occur in 1/3000 births and are defined by variation in aspect of external genital organs, e.g.
- Trial name
- MiniNO (NCT05058781)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Acute Leukemia, Adenomatous Polyposis
Familial Investigations of Childhood Cancer Predisposition
NOTE: This is a research study and is not meant to be a substitute for clinical genetic testing. Families may never receive results from the study or may receive results many years from the time they enroll.
- Conditions
- Acute Leukemia, Adenomatous Polyposis, Adrenocortical Carcinoma, AML
- Trial name
- SJFAMILY (NCT03050268)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- St. Jude Children's Research Hospital
Preterm Birth, Postpartum Depression
COntact RElationship in Neonatal Intensive Care Unit
The present research project aims to explore the value that contact relationships between caregivers and the preterm infant may have in terms of promoting developmental and maturational processes,by attending to the…
- Trial name
- CORE in NICU (NCT06462638)
- Testing
- Neurobehavioral states and physiological parameters evaluation, Maternal vocal pitch evaluation to assess depressive/anxious state
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Bronchopulmonary Dysplasia, Preterm Infant Development
PremaBiom: Metatranscriptomics of the Respiratory Microbiome to Predict the Occurrence of Bronchopulmonary Dysplasia in Preterm Infants
The goal of this clinical trial is to understand the impact of respiratory microbiome maturation in respiratory health of preterm infants under 32 gestational weeks.
- Conditions
- Bronchopulmonary Dysplasia, Preterm Infant Development, Asthma Childhood, Bronchiolitis
- Trial name
- PremaBiom (NCT07411261)
- Testing
- Nasal swab, blood sampling, Mother milk sampling
- Where
- 6 sites in France
- Volunteers
- 270 people
- Sponsor
- University Hospital, Caen
Breastfeeding, Exclusive
Avocado Consumption, Nutrients in Human Milk, and Infant Cognitive Development
The goal of this interventional study is to establish a whole food, avocado, as a viable study material to supplement mothers and infants with nutrients that support optimal brain development.
- Trial name
- NCT06208085
- Testing
- Avocado
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Diet, Mediterranean, Pregnancy Related
Intervention Based on the Mediterranean Diet During Pregnancy and the First Two Years for the Improvement of Neurological Development
The main objective is to evaluate the effect of the Mediterranean diet during pregnancy and the first two years of the child\'s life on the child\'s neurodevelopment and behavior (externalizing and…
- Conditions
- Diet, Mediterranean, Pregnancy Related, Child Development, Infant Behaviour
- Trial name
- CONMED (NCT06614413)
- Testing
- Neurodevelopment and behaviour assesment 2 years old
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Paz
Puberty
Minipuberty of Infancy and the Timing of Pubertal Development in Adolescence: a Follow-up of the Infant Feeding and Early Development (IFED) Cohort
Background: Earlier puberty is associated with adverse health throughout a person s life. The average age when puberty begins has been declining over the past decades in girls, and may also be declining in boys.
- Trial name
- NCT05463120
- Where
- 2 sites in United States
- Volunteers
- 566 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Prematurity
Different Intervention Models of Premature Infants Based on the ICF Biopsychosocial Model
Prematurity is an important risk factor for delayed neuropsychomotor development. The main objective of this study is to analyze the impact of different intervention models on the neuropsychomotor development of premature babies…
- Trial name
- NCT05989438
- Testing
- Orientations for families, Professional stimulation more orientations for families.
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Postpartum Depression (PPD), Breastfeeding
Methyl Donor-Rich Diet in the Postpartum Period
This study aims to evaluate the effects of a methyl-donor-rich diet during the postpartum period on maternal depression, breastfeeding success, and infant weight.
- Conditions
- Postpartum Depression (PPD), Breastfeeding, Maternal Nutrition, Infant Development
- Trial name
- NCT07887178
- Testing
- Methyl Donor-Rich Dietary Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Term Infant, Late Preterm Infant
Brain Uptrain to Improve Learning and Development
The purpose of this study is to see if an early literacy and developmental program in addition to shared reading can increase developmental test scores at 24 months of age.
- Trial name
- BUILD (NCT06638801)
- Testing
- Coach-led caregiver-implemented early literacy and developmental programming, Reach Out and Read Training
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- University of Alabama at Birmingham
Infant Development
Interactions Between Environmental Exposures and Gut Microbiota in Early Life
Recruit the mothers and their infants who bron in Peking University People's Hospital from 2023 to 2026, to evaluate the interaction between environmental exposure and gut microbiota.
- Trial name
- NCT06479928
- Testing
- delivery mode
- Where
- China
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Cerebral Palsy, Cerebral Palsy (CP)
Assessing Intellectual and Motor Outcomes in High-risk Infants
Cerebral palsy (CP) is a condition when a baby has a brain injury that affects their movement and muscle tone. Some people with CP can have other developmental issues, like learning impairments, but many do not and have isolated…
- Conditions
- Cerebral Palsy, Cerebral Palsy (CP), Cerebral Palsy Children, High-risk Infants
- Trial name
- AIM-High (NCT06857539)
- Where
- 4 sites in Ireland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University College Cork
Massage Effect
Vimala Massage Infantile Colic, Sleep and Development Levels
Objective: The effect of Vimala massage applied by parents on infantile colic, sleep and developmental levels of infants will be investigated.
- Trial name
- VIMCOLSLEEP (NCT06993701)
- Testing
- Vimala Massage Training for Fathers, Control Intervention, Vimala Massage Training for Mothers
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Infant Behavior, Father - Child Relations
Fathers' Involvement in Infant Care and Infants' Development
In the early stages of life, newborns are dependent on caregivers to meet their basic needs for survival, feeding, and care. Generally, mothers assume primary responsibility for meeting their infants' basic needs and providing…
- Trial name
- NCT07627126
- Testing
- The Infant Sensory Profile-2, Fathers' Involvement in Infant Care
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Very Preterm Maturity of Infant, Very Low Birth Weight Infant
Individualized Nutrition to Optimize Preterm Infant Growth and Neurodevelopment
Human milk has several well-established benefits but does not adequately meet the increased nutritional demands of the growing preterm infant, necessitating additional nutrient supplementation in a process known as fortification.
- Trial name
- THRIVE (NCT06266455)
- Testing
- Standardized Fortification, Adjustable Fortification
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's National Research Institute
Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder
Home Play-based Intervention for Parents and Infants
The goal of this clinical trial is to learn whether a 12-week home-based intervention (Sociometric Play-based Remediation of Individual Neurodevelopmental Trajectories (SPRINT)) helps support parenting and the development of…
- Conditions
- Attention-Deficit/Hyperactivity Disorder (ADHD), Autism Spectrum Disorder, Premature Birth, Global Developmental Delay
- Trial name
- SPRINT (NCT07716072)
- Testing
- SPRINT Intervention, Waitlist Protocol
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Nanyang Technological University
Development and Health, Nutrition
Effects of Light Exposure for Postpartum Depression on Infant Development
About 11% of women develop depression and anxiety after giving birth. These symptoms can reduce a mother's quality of life and daily functioning and may negatively affect her child's growth and development.
- Trial name
- Chrono_Baby (NCT07440355)
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Less Than 3 Months Old, Healthy Infants
An Intervention Study in Healthy Infants Aged 0-6 Months With Probiotics Lacticaseibacillus Rhamnosus LRa05 (LRa05) and Bifidobacterium Animalis Subsp. Lactis BLa80 (BLa80) vs. Placebo, for Promoting Gut Microbiome Development.
The probiotics Bifidobacterium animalis subsp. lactis BLa80 and Lacticaseibacillus rhamnosus LRa05 have potential to enhance infant health and development based on previous research conducted on human infants.
- Trial name
- SMILE (NCT07505329)
- Testing
- Probiotic
- Where
- Ireland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University College Cork
Preterm Infant, Breast Feeding
Positive Feeding of the Preterm Infant
The goal of this feasibility study is to assess the feasibility to implement a feeding strategy for preterm infants. The main questions it aims to answer are: Is it feasible to implement the PoP-intervention in a level 3a…
- Conditions
- Preterm Infant, Breast Feeding, Bottle Feeding, Enteral Feeding
- Trial name
- PoP (NCT06189352)
- Testing
- Positive feeding of the preterm infant
- Where
- Norway
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
Infant, Premature, Infant, Low Birth Weight
Global Survey on Newborns' HOspitalisation and Parental Experiences - the HOPE Study
This study aims to explore parents' experiences and emotional burdens related to their newborn's hospital stay using an online survey.
- Conditions
- Infant, Premature, Infant, Low Birth Weight, Parents, Life Change Events
- Trial name
- HOPE (NCT06827028)
- Testing
- N/A, no intervention, participation in survey
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Global Foundation for the Care of Newborn Infants