Clinical trials: Infant Motor Development
Premature Infant
Psychomotor Therapy for Very Premature Infants
Our current reflexion is that sensory dys-stimulations, including vestibule-proprioceptive disorders and unbalanced between brain and brainstem maturation of the neonatal period involve an early deviant development for immature…
- Trial name
- VPI (NCT03093337)
- Testing
- Early post hospital discharge psychomotor therapy
- Where
- 10 sites in France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Toulouse
Congenital Hypothyroidism
Infants With Primary Congenital Hypothyroidism and Development
A review of the literature has focused primarily on the cognitive and motor development of children with congenital hypothyroidism, but no studies on sensory processing skills have been found.
- Trial name
- NCT07280104
- Testing
- neurological status, sensory processing functions, Motor development
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Risky Baby, Motor Development
Are Developmentally At Risky Babies Environmentally Disadvantaged?
A study conducted on infants aged between 3 and 11 months revealed a positive relationship between the home environment and developmental outcomes.
- Conditions
- Risky Baby, Motor Development, Sensory Profiles, Environmental Conditions
- Trial name
- NCT07063966
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Cerebral Palsy
The Small Step Program - Early Intervention for Children With High Risk of Developing Cerebral Palsy
Children with cerebral palsy (CP) have life-long motor disorders caused by brain injuries which occur around birth. These children go through extensive treatment during childhood, but the treatment has generally been started late…
- Trial name
- NCT03264339
- Testing
- Small Step Program
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- St. Olavs Hospital
Premature Birth
Continuity of Leg Movements in VLBW Premature Infants: From Spontaneous Kicking and Supported Stepping to Independent Walking
The purposes of this one-year follow-up study are twofold: (1) to prospectively examine the spontaneous kicking and the supported stepping movement in VLBW premature infants until attainment of independent walking; and (2) to…
- Trial name
- NCT00354783
- Volunteers
- 15 people
- Sponsor
- National Taiwan University Hospital
Prematurity, Extreme Prematurity
Early Intervention Based on Neonatal Crawling in Very Premature Infants at Risk For Neurodevelopmental Disorder
Extreme prematurity is constantly increasing according to the World Health Organization. However, methods to train premature infants at risk of disability is sorely lacking. The goal of this project is to overcome this problem.
- Conditions
- Prematurity, Extreme Prematurity, Infant Development, Brain Damage
- Trial name
- Premalocom2 (NCT06027645)
- Testing
- Crawling stimulation with a mini-skateboard (i.e. the crawliskate)
- Where
- 3 sites in France
- Volunteers
- 50 people
- Sponsor
- Marianne Barbu-Roth
Cerebral Palsy, Cerebral Palsy (CP)
Assessing Intellectual and Motor Outcomes in High-risk Infants
Cerebral palsy (CP) is a condition when a baby has a brain injury that affects their movement and muscle tone. Some people with CP can have other developmental issues, like learning impairments, but many do not and have isolated…
- Conditions
- Cerebral Palsy, Cerebral Palsy (CP), Cerebral Palsy Children, High-risk Infants
- Trial name
- AIM-High (NCT06857539)
- Where
- 4 sites in Ireland
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University College Cork
Neonatal Hyperbilirubinemia
Follow-up of Extreme Neonatal Hyperbilirubinemia in 5-10 Year Old Children: a Danish Population Based Study
The objective of this study was to investigate whether infants with total serum bilirubin > 450 umol/L in the neonatal period and no symptoms or no more than early acute bilirubin encephalopathy develop long term sequelae with…
- Trial name
- NCT01599611
- Testing
- Movement assessment battery for children - 2
- Volunteers
- 128 people
- Sponsor
- University of Aarhus
Autism, Cerebral Palsy
Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers With and Without Cerebral Palsy
Background: New ways to study the brain as people move include near-infrared spectroscopy (NIRS) and electroencephalography (EEG).
- Trial name
- NCT03434080
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cerebral Palsy (CP)
Pilot Study of Whole Body Vibration for Children With Cerebral Palsy (CP) From 12 Months of Age
Cerebral Palsy (CP) is the most common cause of physical disability in childhood. Up to day the investigators have treated children diagnosed cerebral palsy with side-alternating whole body vibration (System Galileo®) from the…
- Trial name
- NCT01491152
- Testing
- Galileo® tilt table for children
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University of Cologne
MLD, Krabbe Disease
Longitudinal Study of Neurodegenerative Disorders
The purpose of this study is to understand the course of rare genetic disorders that affect the brain. This data is being analyzed to gain a better understanding of the progression of the rare neurodegenerative disorders and the…
- Conditions
- MLD, Krabbe Disease, ALD, MPS I
- Trial name
- NCT03333200
- Testing
- Palliative Care, Hematopoetic Stem Cell Transplantation
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of Pittsburgh
Pediatric ALL, Infant Development
PANDA Gym: Automated Assessment of Neurodevelopment in Infants at Risk for Motor Disability
Early childhood detection of motor delays or impairments provides the opportunity for early treatment which improves health outcomes.
- Conditions
- Pediatric ALL, Infant Development, Neurodevelopmental Disorders
- Trial name
- NCT04321200
- Testing
- PANDA Gym, Mobile App
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Maternal Distress, Perinatal Depression
A Common Elements-based Intervention to Improve Maternal Psychological Well-being and Mother-infant Interaction
Background: Millions of children in low resource settings are at high risk of poor development due to factors such as undernutrition, inadequate stimulation and maternal depression.
- Conditions
- Maternal Distress, Perinatal Depression, Development Delay, Language Delay
- Trial name
- NCT04252807
- Testing
- Intervention arm, Treatment as Usual
- Where
- Pakistan
- Volunteers
- 250 people
- Sponsor
- Human Development Research Foundation, Pakistan
Premature Birth
Association Between Mother-Infant Attunement During Interaction and the Quality of General Movements
The proposed research has the potential of contributing to the limited empirical literature on the relationship between maternal sensitivity and motor development of preterm infants.
- Trial name
- NCT01764958
- Where
- Israel
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Assuta Hospital Systems
Healthy, Strabismus
Development of the Eye Motor System During the First 7 Months of Life in Infants With and Without a Family History of Cross-Eye
Little is known about the development of the ocular, or eye, motor system (the parts of the brain that control how the eyes move) in children.
- Trial name
- NCT00001143
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Motor Coordination or Function; Developmental Disorder
Project for Cognitive Advancement in Infants With Neuromotor Disorders
The purpose of this longitudinal study is to examine the ongoing interaction between the domains of cognitive and motor development in infants with neuromotor disability, and to compare outcomes of two groups of infants receiving…
- Trial name
- CAN-Do (NCT02673658)
- Testing
- Motor + problem solving, body weight support training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Duquesne University
Developmental Coordination Disorder, Autism Spectrum Disorder
An Explorative RVA of the Motor Development of Children With DCD <2y
This study compares motor development in three groups of infants (controls, DCD, DCD+ASD) before the age of 2 years using retrospective video analysis of infants in home video contexts.
- Trial name
- RVA_DCD (NCT04126395)
- Testing
- Movement Assessment Battery for Children 2(M-ABC-2), Developmental Coordination Disorder - Questionnaire (DCD-Q), Social Responsiveness Scale 2 (SRS-2)
- Where
- 2 sites in Belgium, Canada
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University Ghent
Preterm, Preterm Infant Development
Nutritional Maturity in Preterm Newborns (Premature Infant Oral Motor Intervention, PIOMI)
Premature Infant Oral Motor Intervention (PIOMI) has been found to improve short-term clinical outcomes in preterm infants and contribute to their feeding skills.
- Trial name
- PIOMI (NCT07894380)
- Testing
- The PIOMI initiative in maternal interaction, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Late Preterm Infant, Motor Development
Sleep Characteristics in Late Premature Infants
Studies examining sleep and developmental parameters in infants have primarily focused on either term or extremely preterm infants.
- Conditions
- Late Preterm Infant, Motor Development, Sleep
- Trial name
- NCT06880588
- Testing
- Brief Infant Sleep Questionnaire, Test of Sensory Function in Infants, Peabody Motor Development Scale-2
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Gazi University
Krabbe Disease
Diffusion Tensor Imaging (DTI) in Infants With Krabbe Disease
This study is designed to learn about early brain development in children with Krabbe disease, and to use diffusion tensor imaging as an early diagnostic tool to identify newborns at risk for the disease.
- Trial name
- NCT00787865
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh