Clinical trials: Infants and Young Children
Polio
Evaluation of Integrating MIYCN Interventions in Existing CGPP of PCI
The study has two arms; both experimental and control areas will receive standard interventions given under polio eradication program of PCI.
- Trial name
- NCT03368885
- Testing
- Maternal dietary diversity, Diet diversity in complementary feeding, Exclusive Breast Feeding
- Where
- India
- Volunteers
- 2,590 people, healthy volunteers welcome
- Sponsor
- FHI 360
Cystic Fibrosis, Pancreatic Insufficiency
Use of Ultrase® MT12 in Young Cystic Fibrosis Children (CF)
Multicenter, explorative, phase IIIb, open-label study to assess the efficacy and safety of Ultrase® MT12, in the control of steatorrhea and clinical signs and symptoms of malabsorption in CF children with pancreatic…
- Trial name
- NCT00880100
- Testing
- Ultrase® MT12
- Where
- 15 sites in United States
- Volunteers
- 49 people
- Sponsor
- Forest Laboratories
Growth Retardation
Intervention in Minimizing Aflatoxins and Fumonisins Exposure to Children Through Food and Breastfeeding in Tanzania
It has been shown that exposure to mycotoxins through complementary foods and breast milk had profound effects on growth of children from 6 months to 1 year of age.
- Trial name
- NCT02438774
- Testing
- post-harvest intervention package, Routine agriculture extension services
- Where
- 3 sites in Tanzania
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tanzania Food and Drugs Authority
Bradycardia, Arrhythmias
Heart Rate Response to Atropine Doses Less Than 0.1mg IV to Anesthetized Infants
An infants heart rate is very important because it ensures that blood is pumped to all organs in the body. Heart rate may decrease during anesthesia and surgery, and this is why the anesthesiologist will often give a medication…
- Trial name
- NCT01819064
- Testing
- Atropine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- State University of New York at Buffalo
Child Malnutrition, Behavior, Maternal
Mobile Gaming App to Improve Child Nutrition in Nigeria
Undernutrition among children born to teenage mothers deserves urgent attention in Nigeria, where 27.2% of girls (15-19 years) living in rural areas have begun childbearing.
- Trial name
- NCT05181293
- Testing
- Mobile Gaming App for Nutrition Intervention
- Where
- Nigeria
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Obesity
Infant Nutrition: Evaluation of an Educational Touchscreen Computer Program
The investigators are recruiting participants for a randomized controlled trial to evaluate the usability and educational value of a nutrition education touchscreen computer program targeting Spanish-speaking Latina caregivers of…
- Trial name
- NCT01272492
- Testing
- Computer Use
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Infant
Exploration of Infant and Young Child Feeding Practices and Their Determinants
The goal of this observational study is to assess infant and young child-feeding practices among women living in urban areas and slums in Pune and rural areas around Pune, India, and to investigate the reasons for the adopted…
- Trial name
- NCT06307951
- Testing
- No intervention
- Where
- India
- Volunteers
- 271 people
- Sponsor
- Hirabai Cowasji Jehangir Medical Research Institute
Undernutrition, Healthy Nutrition
Women Supporting Women to Improve Infant and Child Feeding Practices
Undernutrition in the first 2 years of life is the largest preventable cause of death before age 5. Among those who survive, stunting before age two leaves millions with lifelong physical and cognitive deficits, which are…
- Conditions
- Undernutrition, Healthy Nutrition, Health Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT05473312
- Testing
- Community Sensitization, 28-day PD/Hearth Sessions, Supplemental Print Information
- Where
- Pakistan
- Volunteers
- 350 people
- Sponsor
- Aga Khan University
Feeding Behavior, Maternal Health
Maternal Employment in Low and Middle-income Countries and Infant Feeding
Using cross-sectional samples from over 40 Demographic and Health Surveys, the investigators studied the association between maternal employment and 3 indicators of Infant and Young Child Feeding (IYCF): exclusive breastfeeding…
- Trial name
- NCT03209999
- Where
- United States
- Volunteers
- 39,791 people
- Sponsor
- University of Washington
Nutritional Anemia, Infant Morbidity
Impact of Low Dose Iron-containing Micronutrient Powders on Iron Status and Morbidity of Young Children in Ethiopia
The purpose of the study is to assess the safety of iron supplementation in MNPs. A quasi-experimental matched-control cluster design will be used in, purposely selected, 18 intervention and 18 matched-control clusters of Oromia…
- Trial name
- NCT02479815
- Testing
- Micronutrient Powder (MNP)
- Where
- Ethiopia
- Volunteers
- 2,356 people, healthy volunteers welcome
- Sponsor
- Ethiopian Public Health Institute
Cystic Fibrosis
Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children
This is a two-part, multi-center, prospective longitudinal, exploratory study of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators and their impact on children with cystic fibrosis (CF).
- Trial name
- BEGIN (NCT04509050)
- Testing
- Ivacaftor or elexacaftor/tezacaftor/ivacaftor
- Where
- 35 sites in United States
- Volunteers
- 210 people
- Sponsor
- Sonya Heltshe
Functional Constipation, Therapeutic Touch
Effect of Therapeutic Touch on Functional Constipation in Infants and Young Children
The aim of the study is to determine the effect of therapeutic touch on functional constipation in infants and young children.
- Conditions
- Functional Constipation, Therapeutic Touch, Infants, Children
- Trial name
- NCT06353841
- Testing
- Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Haematological Malignancy, Acute Leukemia
A Study to Assess a Physical Activity Program in Children, Adolescents and Young Adults Requiring Hematopoietic Stem Cell Allografts
To date, allogeneic haematopoietic stem cell transplantation (aHSCT) is the only curative treatment for many paediatric and young adult haematological pathologies (acute leukaemia, myelodysplastic syndromes, haemoglobinopathies…
- Conditions
- Haematological Malignancy, Acute Leukemia, Myelodysplastic Syndromes, Hemoglobinopathy in Children
- Trial name
- EVAADE (NCT04331483)
- Testing
- Physical activity program
- Where
- France
- Sponsor
- Centre Leon Berard
EBV Viremia, CMV Viremia
25BT056: Basket Study of Viral Cytotoxic T Lymphocytes
This study is evaluating the safety and effectiveness of virus-specific cytotoxic T lymphocytes (vCTLs) for treating difficult-to-control viral infections caused by cytomegalovirus (CMV), adenovirus (ADV), Epstein-Barr virus…
- Conditions
- EBV Viremia, CMV Viremia, BK Viremia, Adenovirus
- Trial name
- NCT07873970
- Testing
- Virus-Specific Cytotoxic T Lymphocytes (vCTLs)
- Volunteers
- 35 people
- Sponsor
- Children's Hospital of Philadelphia
Diabetes Mellitus, Type 2
Water Up@ At Home: An Intervention to Replace Sugary Drinks With Water
This study will test the preliminary effects of an intervention to reduce sugary drinks among low-income parents (n=38)(primary caregivers) and their young children (6 months-3 year olds) compared to a control group (n=38).
- Trial name
- NCT05159622
- Testing
- Water Up! at Home
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- George Washington University
Healthy Children
Study to Evaluate the Effects of a Formula on the Gut Health of Healthy Chinese Infants and Young Children
The infant gut microbiota, a major driver of the maturation of the immune system, is formed through the successive establishment and development during infancy and early childhood.
- Trial name
- NCT04864665
- Testing
- a formula with prebiotics and milk fat
- Where
- 6 sites in China
- Volunteers
- 455 people, healthy volunteers welcome
- Sponsor
- Danone Nutricia
Infant, Small for Gestational Age
Genotropin Treatment In Very Young Children Born Small For Gestational Age
To demonstrate the effect on height and psychomotor development of Growth Hormone treatment in very young children starting at an age of 2 years.
- Trial name
- EGN (NCT00627523)
- Testing
- Genotropin (PN-180,307) Somatropin, Control-no treatment
- Where
- 17 sites in Belgium, Czechia and 7 more
- Volunteers
- 43 people
- Sponsor
- Pfizer
Nutrition Status
Healthynsect Child Growth and Health Intervention Study
Malnutrition in all its forms is still a problem in resource limited settings including Kenya driven by low diet quality, food preparation and feeding practices including hygiene.
- Trial name
- HEALTHYNSECT (NCT06002620)
- Testing
- CSB+, Enriched nutrition food (CEF), Nutrition education
- Where
- Kenya
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Diabetes Mellitus, Type I
The Effectiveness of Continuous Glucose Monitoring in Diabetes Treatment for Infants and Young Children
The purpose of this study is to see if the use of a real-time glucose sensor improves diabetes control in young children (less than 4 years old) with Type I diabetes when they are initiated on insulin pump therapy.
- Trial name
- Gerber RTSA (NCT00875290)
- Testing
- Real-time glucose sensor
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Seattle Children's Hospital
Education on Feeding and Health Status
To Evaluate the Effect of Nutrition Education on Infants and Young Children's Nutritional and Health Status in East Wollaga Zone
Child undernutrition is the principal cause of child morbidity and mortality worldwide. It manifests in different forms including stunting, wasting, underweight, and micronutrient deficiencies.
- Trial name
- NCT05503654
- Testing
- Nutrition education
- Where
- Ethiopia
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Jimma University