Clinical trials: Infants in Neonatal Intensive Care Units
Respiratory Distress Syndrome (RDS), Infant, Premature, Diseases
FiO2 Delivered With Neonatal bCPAP
Continuous positive airway pressure (CPAP) is the mainstay of treatment recommended for preterm infants with respiratory distress syndrome in all resource contexts.
- Conditions
- Respiratory Distress Syndrome (RDS), Infant, Premature, Diseases, Infant, Newborn, Diseases
- Trial name
- NCT06615427
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Infants in Neonatal Intensive Care Units
Improving Antimicrobial Prescribing Practices in the Neonatal ICU
To determine if 3 randomly assigned bundles of stewardship interventions would reduce overall and inappropriate antimicrobial use in the neonatal intensive care unit (NICU), a pre-post study was performed in 4 NICUs.
- Trial name
- iNAP (NCT03079245)
- Testing
- Education Plus (E+), Clinical Decision Support, Prescriber Audit and Feedback
- Where
- 4 sites in United States
- Volunteers
- 6,184 people
- Sponsor
- Columbia University
Physical Therapy, NICU Infants
Immersive Physical Therapy in the Neonatal Intensive Care Unit (NICU)
To learn if and how the physical and occupational therapy program in the Newborn Critical Care Center helps parents with their stress levels and ability to meet the needs of their preterm infants.
- Trial name
- NCT06927037
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of North Carolina, Chapel Hill
Skin to Skin, Premature Newborns
Skin-to-skin Contact During the Transfer From the Delivery Room to the Neonatal Intensive Care Unit: Impact on Very Preterm Infants and Their Parents
Developmental care are recognized as a standard of care for preterm infants in neonatal intensive care units. Regular skin-to skin contacts during the neonatal stay show short and long-term beneficial effects on preterm infants…
- Trial name
- TRANSPAPNEO (NCT05820386)
- Testing
- Skin-to-skin Contact (SSC), Incubator
- Where
- 4 sites in France
- Volunteers
- 118 people
- Sponsor
- University Hospital, Tours
Newborn, Anxiety
Stress and Anxiety Levels of Mothers Lying in the Baby Newborn Intensive Care Unit
Although coronaviruses (CoV) cause mild infections in the community, such as colds, they can also cause more severe infections. There are many subspecies of coronaviruses that can pass from animals to humans and can be…
- Trial name
- NCT04386798
- Testing
- survey work
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Premature Birth, Respiratory Distress Syndrome, Newborn
Non-invasive Neurally Adjusted Ventilator Assist or Continuous Positive Airway Pressure in Preterm Infants
Strategies to prevent lung injury, facilitate lung development, and to support the preterm infant's capacity to breathe are decisive.
- Trial name
- NCT04333563
- Testing
- CPAP, NIV NAVA
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- St. Olavs Hospital
Neonatal Intensive Care Units, Premature Infant
Virtual Reality-Enhanced Parent Education in Neonatal Intensive Care
This randomized pilot clinical trial aims to evaluate the effectiveness and feasibility of virtual reality (VR)-enhanced parent education in improving neonatal intensive care unit (NICU) caregiving practices among parents of…
- Conditions
- Neonatal Intensive Care Units, Premature Infant, Parent Education, Virtual Reality
- Trial name
- NCT07410858
- Testing
- Virtual Reality-Enhanced Parent Education
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Jouf University
Infant, Premature
The Impact of Implementing NIDCAP on Preterm Infants in the NICU
The purpose of this study is to evaluate the impact of the NIDCAP program of individualized patient consultation on the neurobehavioral organization of transported preterm infants in the NICU.
- Trial name
- NCT00179933
- Testing
- Newborn Individualized Assessment Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Preterm Infants, Parent-Child Relations
Impact of Videoconference Updates in Neonatal Intensive Care Unit on Parental Stress of Preterm Infants (VISIO-NEONAT)
The aim of the study is to test the effect of daily videoconference updates between parents of preterm newborns and health care providers which also offer them the possibility of seeing their child on the parental stress in a…
- Conditions
- Preterm Infants, Parent-Child Relations, Parental Stress, Post Partum Depression
- Trial name
- NCT03438071
- Testing
- Videoconferencing
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Poitiers University Hospital
Catheterization
Study of Chlorhexidine as the Hub Antiseptic to Prevent Catheter Related Infections in Newborn Infants
The purpose of this study is to prevent catheter-related infections in newborn infants admitted to the Neonatal Intensive Care Unit (NICU).
- Trial name
- NCT00516360
- Testing
- 3.15% chlorhexidine as daily antiseptic on needleless access port
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Practice Guideline of Erythrocyte Transfusion in Preterm Infant
Red Blood Cell Transfusion in Very Premature Infants and HAS 2014 Guideline
The indications that motivated the decision to transfuse (or not) were analyzed to verify compliance with HAS recommendations. Medical records from 57 premature infants < 32 weeks hospitalized between 2016 -2017 were…
- Trial name
- RBCPREM (NCT03599167)
- Where
- France
- Volunteers
- 57 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Neonatal Abstinence Syndrome
Actigraphy and Neonatal Abstinence Syndrome of Hospitalized Newborn in Intensive Care Units
The aim of this study is to analyse the correlation between actigraphy and Lipsitz scoring system in neonatal opioid abstinence syndrome of hospitalized newborn in intensive care units
- Trial name
- ACTINEO2 (NCT04983563)
- Testing
- Actigraphy, eTact
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Shock, Sepsis
Hemodynamic Evaluation of Preload Responsiveness in Children by Using PiCCO
The purpose of this study is To assess the value of dynamics (SVV, PPV) and static indices (GEDVI, ITBVI, CVP) of preload and its combination with contractility (CI,SV, ventricular power, dP/dtmax, CFI, GEF) and lung water…
- Conditions
- Shock, Sepsis, Systemic Inflammatory Response Syndrome, Low Cardiac Output
- Trial name
- PreloaDren (NCT01157299)
- Where
- 7 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario La Paz
Very Low Birth Weight Infant
The Effect of Family Integrated Care on Melatonin Level in Very Low Birth Weight Infants
This study will explore the effect of Family integrated care (FICare) on the level of melatonin and other clinical outcomes in very low birth weight infants (VLBWIs) by integrating families into the neonatal intensive care unit…
- Trial name
- NCT05483231
- Testing
- Family integrated care intervention group, Routine nursing care group
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Children's Hospital of Fudan University
Motor Delay, Premature Birth
Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit
Study Aims Pilot study: Due to the large recruitment goal and length of the project, the study team/PIs will evaluate the first cohort of 6-10 participants to refine study procedures and study-related materials.
- Conditions
- Motor Delay, Premature Birth, Intraventricular Hemorrhage, Hypoxic-Ischemic Encephalopathy
- Trial name
- NCT05568264
- Testing
- Physical Therapy intervention
- Where
- 3 sites in United States
- Volunteers
- 222 people
- Sponsor
- Shirley Ryan AbilityLab
Breast Feeding
Comparison of Breastfeeding Teaching Intervention
Investigators plan to include mother-infant couplets admitted to Neonatal Intensive Care Unit(NICU) at Brookdale Hospital for clinical reasons during one year period 1/2018-1/2019.
- Trial name
- BFTS (NCT03602729)
- Testing
- Breastfeeding education
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Brookdale University Hospital Medical Center
Prematurity, Maternal Anxiety
Maternal Singing During Kangaroo Care in Preterm Infants
Study objective is to evaluate the additive effect of maternal singing during skin to skin contact (Kangaroo Care) on anxiety reduction both to infants and their mothers.
- Trial name
- NCT01427894
- Testing
- Maternal singing with Kangaroo Care
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Meir Medical Center
Stress, Psychological
The Effect of Supportive Nursing Interventions of Mothers of Infants in Neonatal Intensive Care Unit
Objective: This study was conducted to determine the effects of supportive interventions on the stress levels of mothers of infants hospitalized in the Neonatal Intensive Care Unit (NICU).
- Trial name
- NCT04830150
- Testing
- Supportive interventions on the stress levels of mothers of infants hospitalized in the Neonatal Intensive Care Unit (NICU).
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Ordu University
Late Onset Neonatal Sepsis, Necrotising Enterocolitis
Lactoferrin Prophylaxis in VLBW and Regulator T-cells
The aim of the study is to evaluate whether oral administration of 200 mg/day lactoferrin (LF) to very low birth weight infants reduces late onset sepsis and necrotising enterocolitis and the effect of LF on regulatory T cells.
- Conditions
- Late Onset Neonatal Sepsis, Necrotising Enterocolitis, Very Low Birth Weight Infants
- Trial name
- NCT01287507
- Testing
- Lactoferrin (bovine origin)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara University
Premature Birth
Evaluation of Pulse Oximetry Sensors in Neonates
The purpose of this study is to evaluate sensor longevity and skin integrity with two different models of neonatal pulse oximetry sensors currently used for monitoring oxygen levels in small infants.
- Trial name
- NCT00179972
- Testing
- Adhesive and non-adhesive oximetry sensors
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago