Clinical trials: Infarction, Myocardial
Acute Respiratory Distress Syndrome, Cardiogenic Shock
Study of Immunity Dysfunction Induced by Extracorporeal Assistance (ECMO / ECLS)
Study of immunosuppression biomarkers in patients with ARDS or cardiogenic shock with ECMO / ECLS, compared to patients with ARDS or cardiogenic shock without ECMO / ECLS
- Trial name
- IMPEC (NCT03262155)
- Testing
- Blood test
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Rennes University Hospital
Acute Coronary Syndrome, Lipoproteinemia
Influence of Pelacarsen on Patients After Myocardial Infarction With High Lp(a) Values (PEMILA)
The aim of study is to examine the relationship between lipid subfractions, inflammation and structural-functional properties of the arterial wall in patients after myocardial infarction with high lipoprotein (a) (Lp (a)) levels…
- Conditions
- Acute Coronary Syndrome, Lipoproteinemia, Inflammation, Genetic Polymorphisms
- Trial name
- NCT04993664
- Testing
- Pelacarsen (TQJ230)
- Where
- Slovenia
- Sponsor
- University Medical Centre Ljubljana
Cardiogenic Shock, Acute Myocardial Infarction
Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock
The study compares the therapies of instant multivessel balloon angioplasty plus stent implantation or the balloon angioplasty plus stent implantation of the infarct artery alone with any possible graduated later treatment of the…
- Conditions
- Cardiogenic Shock, Acute Myocardial Infarction, Complications
- Trial name
- CULPRIT-SHOCK (NCT01927549)
- Testing
- Immediate multivessel PCI, Culprit Lesion only PCI
- Where
- 3 sites in Germany
- Volunteers
- 706 people
- Sponsor
- University of Luebeck
Stable Angina, Unstable Angina
Clinical Performance of CRE8 Drug Eluting Stent in All Comer Population
The aim of this study is to evaluate safety and efficacy performances of CRE8 Drug Eluting Stent, in patients comparable to the everyday's clinical practice population, with a specific focus on diabetics, that will be part of a…
- Conditions
- Stable Angina, Unstable Angina, Acute Myocardial Infarction
- Trial name
- PARTICIPATE (NCT01556126)
- Testing
- Amphilimus Eluting Stent (CRE8)
- Where
- 23 sites in Austria, Belgium and 4 more
- Volunteers
- 1,191 people
- Sponsor
- CID - Carbostent & Implantable Devices
Cardiogenic Shock
Clinical Study of Extra-Corporal Life Support in Cardiogenic Shock Complicating Acute Myocardial Infarction
This study compares standard treatment plus Extra-Corporal Life Support (ECLS) versus standard treatment alone in patients with cardiogenic shock due to myocardial infarction.
- Trial name
- ECLS-SHOCK (NCT02544594)
- Testing
- Extra-Corporal Life Support (ECLS)
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- LMU Klinikum
Hypovolemic Shock, Cardiogenic Shock
Renal Resistive Index in Patients With Shock
This study consists of two substudies. The first substudy: 'Renal resistive index in critically ill patients with cardiogenic and septic shock' Design: cross-sectional observational Aim of this project is: 1.
- Conditions
- Hypovolemic Shock, Cardiogenic Shock, Septic Shock, Kidney Failure, Acute
- Trial name
- NCT02558166
- Where
- Netherlands
- Volunteers
- 92 people
- Sponsor
- Amsterdam UMC, location VUmc
Sepsis, Post Cardiac Surgery Low Output Syndrome Requiring Inotropic/Vasopressor Therapy
Comparison of Central Venous Oxygen Saturation Measurements by Non-invasive Mespere Venous Oximeter and Central Venous Catheter
The intent of this study is to validate the venous blood oxygenation measurements of the Mespere VA Oximeter compared to the saturations measured by venous blood sampling through an inserted central vein catheter, which is…
- Conditions
- Sepsis, Post Cardiac Surgery Low Output Syndrome Requiring Inotropic/Vasopressor Therapy, Cardiogenic Shock Post Myocardial Infarction, Hypoxemic Respiratory Failure.
- Trial name
- NCT01788956
- Testing
- Mespere Venous Oximeter, Co-Oximeter
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Mespere Lifesciences Inc.
Coronary Disease, Coronary Artery Ectasia
Outcomes After PCI of the Aneurysmatic Right Coronary Artery
This study aims to evaluate procedural and clinical outcomes of acute coronay syndrome (ACS) patients with aneurysmatic culprit right coronary artery (RCA).
- Conditions
- Coronary Disease, Coronary Artery Ectasia, Right Coronary Artery Occlusion, Right Coronary Artery Stenosis
- Trial name
- RIGHT-MARE (NCT05713201)
- Testing
- Percutaneous Coronary Intervention
- Where
- 8 sites in Italy, Spain
- Volunteers
- 90 people
- Sponsor
- San Luigi Gonzaga Hospital
Healthy Volunteers
Study to Compare the Pharmacodynamics and Pharmacokinetics of Acetylsalicylic Acid Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Healthy Adults.
The goal of this clinical trial is to compare the pharmacodynamics (PD), pharmacokinetics (PK), safety, and tolerability of acetylsalicylic acid powder for oral inhalation (i-ASA) with non-enteric-coated chewable aspirin (C-ASA)…
- Trial name
- NCT05625334
- Testing
- ASA, non-enteric-coated chewable aspirin
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Vectura, Inc.
Atrial Fibrillation New Onset, Acute Myocardial Infarction
BurdEn of NEw Onset Atrial FIbrillation in patienTs With Acute Myocardial Infarction
To validate the prognostic importance of the burden of new-onset atrial fibrillation (NOAF) complicating acute myocardial infarction (AMI) in a prospectively designed hospital-based registry.
- Trial name
- BENEFIT-AMI (NCT04528511)
- Testing
- Continuous Electronic Monitor
- Where
- 5 sites in China
- Volunteers
- 774 people
- Sponsor
- Shanghai 10th People's Hospital
Death, Sudden, Ventricular Tachycardia
Prognosis Impact of NSVTs After an AMI (TeVeO Study).
Nowadays, Sudden Cardiac Death (SCD) due to malignant arrhythmias is an important cause of death among acute myocardial infarction (AMI) survivors.
- Conditions
- Death, Sudden, Ventricular Tachycardia, Implantable Defibrillator User, Myocardial Infarction
- Trial name
- TeVeO (NCT04765943)
- Testing
- Implantable Loop Recorder implant
- Where
- Spain
- Volunteers
- 224 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Acute Myocardial Infarction
Interest of COLchicine in the Treatment of Patients With Acute Myocardial INfarction and With Inflammatory Response
Background: Colchicine is an old well-known venerable drug routinely used in gout attacks for instance. More recnetly it is regularly use in the treatment of pericarditis.
- Trial name
- COLIN (NCT02363725)
- Testing
- Colchimax®, Conventional treatment
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Montpellier
STEMI
Efficacy and Safety on Prouk for STEMI Patients in China
The purpose of the study is to evaluate the efficacy and safety of rh-prouk as pharmacoinvasive therapy on those ST Elevated Myocardial Infarctions patients, it is designed as a multicenter, active controlled, single blinded…
- Trial name
- NCT02367976
- Testing
- rhprouk
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Suzhou RxD Biopharmaceutical Co., Ltd
Stable Angina, Unstable Angina
Prospective, Single-arm, Multicenter Study for Evaluation the Safety and Effectiveness of the ALEX Stent in a Real-world Setting of Percutaneous Coronary Interventions in Patients With Coronary Heart Disease
To evaluate the safety and effectiveness of the ALEX stent in a real-world setting of percutaneous coronary interventions in patients with coronary heart disease.
- Conditions
- Stable Angina, Unstable Angina, Myocardial Infarction
- Trial name
- ALEX OCT (NCT01637012)
- Testing
- Implantation
- Where
- 5 sites in Poland
- Volunteers
- 60 people
- Sponsor
- Balton Sp.zo.o.
Myocardial Infarction, Heart Failure
A Study of VentriGel in Post-MI Patients
This Phase I, open label, study will investigate the effects of VentriGel injection in patients who have experienced a first, large ST elevation myocardial infarction (STEMI) treated by PCI within the past 3 years and have…
- Conditions
- Myocardial Infarction, Heart Failure, Left Ventricular Remodeling
- Trial name
- NCT02305602
- Testing
- VentriGel
- Where
- 6 sites in United States
- Volunteers
- 15 people
- Sponsor
- Ventrix, Inc.
Left Ventricular Remodeling, Acute Myocardial Infarction
Danlou Tablets to Prevent Left Ventricular Remodeling
Danlou tablets are Chinese patent medicine which has been approved in China for the treatment of ischemic heart disease, but the evidence supporting its efficacy on cardiac remodeling remains unclear.
- Trial name
- NCT02675322
- Testing
- Danlou Tablets
- Volunteers
- 82 people
- Sponsor
- shuai Mao
ST Elevation Myocardial Infarction, Multi-Vessel Coronary Artery Stenosis
Quantitative Fractional Ratio-guided Revascularization in STEMI Patients With Multi-vessel Disease
About half of patients with ST-segment elevation myocardial infarction (STEMI) have multi-vessel lesions (> 50% diameter stenosis). But how to deal with the non-culprit vessels is still controversial.
- Trial name
- NCT04259853
- Testing
- PCI
- Where
- 15 sites in China
- Volunteers
- 1,016 people
- Sponsor
- Fujian Medical University
Heart Failure, Cardiogenic Shock
Ivabradine Effects in Cardiogenic Shock Requiring Inotropic Support
Data regarding the safety and efficacy of ivabradine use in severely decompensated HFrEF requiring inotropic support is limited to case series.1 This study aimed to evaluate ivabradine safety and tolerability in admitted…
- Conditions
- Heart Failure, Cardiogenic Shock, Ischemic Heart Disease
- Trial name
- IVA-CS (NCT05594342)
- Testing
- Ivabradine 7.5Mg Tab, DOBUTamine Injectable Solution
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- The Young Investigator Group of Cardiovascular Research
Acute Myocardial Infarction (AMI), Periodontal Disease
Myocardial Infarction and Periodontitis: Periodontal Health Intervention.
The aim of this study is to establish a shared database of acute myocardial infarction patients with periodontitis, to clarify the clinical benefits of periodontitis intervention on acute myocardial infarction patients through…
- Trial name
- NCT06745141
- Testing
- Periodontal surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai 10th People's Hospital
Post-Infarction Heart Rupture, Gene Polymorphism
PCSK9 Polymorphism and Risk of Cardiac Rupture
Protein convertase subtilisin/kexin type 9 (PCSK9) plays a regulatory role in cholesterol homeostasis by promoting low-density lipoprotein receptor (LDLr) degradation.
- Trial name
- NCT05503095
- Testing
- Genetic analysis for PCSK9 polymorphisms
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Maastricht University Medical Center